| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucia Moravcikova, Roman Moravcik, Daniela Jezova, Lubica Lacinova, Eliyahu Dremenco. Delta-opioid receptor-mediated modulation of excitability of individual hippocampal neurons: mechanisms involved. Pharmacological reports : PR. vol 73. issue 1. 2021-09-08. PMID:33161533. |
delta-opioid receptor (dor)-mediated modulation of hippocampal neural networks is involved in emotions, cognition, and in pathophysiology and treatment of mood disorders. |
2021-09-08 |
2023-08-13 |
Not clear |
| Mohammed A H Alnoud, Wen Chen, Nana Liu, Wei Zhu, Jing Qiao, Shujuan Chang, Yukang Wu, Shanshan Wang, Yiwei Yang, Qiaoyi Sun, Jiuhong Kan. Sirt7-p21 Signaling Pathway Mediates Glucocorticoid-Induced Inhibition of Mouse Neural Stem Cell Proliferation. Neurotoxicity research. vol 39. issue 2. 2021-07-31. PMID:33025360. |
prenatal glucocorticoid (gc) overexposure impacts fetal hippocampal neural stem cells (nscs) and increases the risk for relative cognitive and mood disorders in offspring. |
2021-07-31 |
2023-08-13 |
mouse |
| Yong Wang, Xiao-Yu Yin, Xue He, Chen-Mao Zhou, Jin-Chun Shen, Jian-Hua Ton. Parvalbumin interneuron-mediated neural disruption in an animal model of postintensive care syndrome: prevention by fluoxetine. Aging. vol 13. issue 6. 2021-07-22. PMID:33619236. |
accumulating evidence has demonstrated that hippocampal gabaergic interneuron dysfunction is implicated in various mood disorders induced by stress. |
2021-07-22 |
2023-08-13 |
human |
| Cristian Moreno, Tamara Hermosilla, Paulina Hardy, Víctor Aballai, Patricio Rojas, Diego Varel. Ca Cells. vol 9. issue 12. 2021-07-09. PMID:33291797. |
ca functional and morphological modifications in the brain caused by major mood disorders involve many brain areas, including the hippocampus, leading to cognitive and mood alterations. |
2021-07-09 |
2023-08-13 |
Not clear |
| Lan Xiao, Vinay Kumar Sharma, Leila Toulabi, Xuyu Yang, Cheol Lee, Daniel Abebe, Areg Peltekian, Irina Arnaoutova, Hong Lou, Y Peng Lo. Neurotrophic factor-α1, a novel tropin is critical for the prevention of stress-induced hippocampal CA3 cell death and cognitive dysfunction in mice: comparison to BDNF. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33414376. |
stress leads to brain pathology including hippocampal degeneration, cognitive dysfunction, and potential mood disorders. |
2021-06-18 |
2023-08-13 |
mouse |
| Carey Wilson, Jake Rogers, Feng Chen, Shanshan Li, Paul A Adlard, Anthony J Hannan, Thibault Renoi. Exercise ameliorates aberrant synaptic plasticity without enhancing adult-born cell survival in the hippocampus of serotonin transporter knockout mice. Brain structure & function. vol 226. issue 6. 2021-06-15. PMID:34052925. |
deficits in hippocampal cellular and synaptic plasticity are frequently associated with cognitive and mood disorders, and indeed common mechanisms of antidepressants are thought to involve neuroplastic processes. |
2021-06-15 |
2023-08-13 |
mouse |
| Hansruedi Büele. Mitochondrial and Autophagic Regulation of Adult Neurogenesis in the Healthy and Diseased Brain. International journal of molecular sciences. vol 22. issue 7. 2021-06-09. PMID:33805219. |
defects of adult hippocampal neurogenesis have been linked to cognitive decline and dysfunction during natural aging and in neurodegenerative diseases, as well as psychological stress-induced mood disorders. |
2021-06-09 |
2023-08-13 |
Not clear |
| Silvia Vincentiis, Juliana A Alcantara, Patricia Rzezak, Daniel S Kerr, Wagner F Gattaz, Helio van der Linden, Bernardo Dos Santos, Francisco Arruda, Tiffany Chaim-Avancini, Mauricio H Serpa, Fernando Fernandes, Ricardo A Moreno, Geraldo F Busatto, Ruda Alessi, Renata Demarque, Kette D Valent. Genetic polymorphisms of the serotonin transporter are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. Epilepsy & behavior : E&B. vol 117. 2021-04-20. PMID:33639436. |
mood disorders are the most frequent psychiatric disorders in patients with temporal lobe epilepsy caused by hippocampal sclerosis (tle-hs). |
2021-04-20 |
2023-08-13 |
Not clear |
| Francis M Hughes, Nathan A Hirshman, Hamza A Malick, Simon W White, Huixia Jin, Shelby N Harper, J Todd Purve. A possible mechanism underlying mood disorders associated with LUTS: Chronic bladder outlet obstruction causes NLRP3-dependent inflammation in the hippocampus and depressive behavior in rats. Neurourology and urodynamics. vol 39. issue 6. 2021-03-25. PMID:32602164. |
a possible mechanism underlying mood disorders associated with luts: chronic bladder outlet obstruction causes nlrp3-dependent inflammation in the hippocampus and depressive behavior in rats. |
2021-03-25 |
2023-08-13 |
rat |
| Bruce S McEwe. Hormones and behavior and the integration of brain-body science. Hormones and behavior. vol 119. 2020-12-01. PMID:31790663. |
hormone actions in hippocampus have revealed its capacity, and that of other brain regions, for adaptive plasticity, loss of which needs external intervention in, for example, mood disorders. |
2020-12-01 |
2023-08-13 |
Not clear |
| Swati Maitra, Nitin Khandelwal, Scherazad Kootar, Pooja Sant, Salil S Pathak, Sujatha Reddy, Annapoorna P K, Upadhyayula Suryanarayana Murty, Sumana Chakravarty, Arvind Kuma. Histone Lysine Demethylase JMJD2D/KDM4D and Family Members Mediate Effects of Chronic Social Defeat Stress on Mouse Hippocampal Neurogenesis and Mood Disorders. Brain sciences. vol 10. issue 11. 2020-12-01. PMID:33182385. |
histone lysine demethylase jmjd2d/kdm4d and family members mediate effects of chronic social defeat stress on mouse hippocampal neurogenesis and mood disorders. |
2020-12-01 |
2023-08-13 |
mouse |
| Michael Popiolek, Yukitoshi Izumi, Allen T Hopper, Jing Dai, Silke Miller, Hong-Jin Shu, Charles F Zorumski, Steven Menneric. Effects of CYP46A1 Inhibition on Long-Term-Depression in Hippocampal Slices Frontiers in molecular neuroscience. vol 13. 2020-11-17. PMID:33192294. |
effects of cyp46a1 inhibition on long-term-depression in hippocampal slices the manipulation of cholesterol and its metabolites has been hypothesized to be therapeutically beneficial for mood disorders, neurodegenerative disorders, and epilepsies. |
2020-11-17 |
2023-08-13 |
mouse |
| John Afees Olanrewaju, Joshua Oladele Owolabi, Ifedamola Patience Awodein, Joseph Igbo Enya, Stephen Taiye Adelodun, Sunday Yinka Olatunji, Sunday Oluwaseyi Fabiy. Journal of experimental pharmacology. vol 12. 2020-11-13. PMID:33173355. |
repeated and regimented treatment with reserpine causes depression-like condition characterized by persistent mood disorder, feelings of severe despondency and dejection, thus altering the hippocampal morphology. |
2020-11-13 |
2023-08-13 |
Not clear |
| Yuan Zhou, Hao-Kang Zhang, Fei Liu, Gang Lei, Peng Liu, Tong Jiao, Yong-Hui Dan. Altered Light Conditions Contribute to Abnormalities in Emotion and Cognition Through HINT1 Dysfunction in C57BL/6 Mice. Frontiers in behavioral neuroscience. vol 12. 2020-09-29. PMID:29937721. |
based on the potential links between histidine triad nucleotide binding protein 1 (hint1) and mood disorders, we also examined the expression of hint1 and related apoptosis factors in the suprachiasmatic nucleus (scn), prefrontal cortex (pfc), nucleus accumbens (nac) and hippocampus (hip). |
2020-09-29 |
2023-08-13 |
mouse |
| Peter Illes, Alexei Verkhratsky, Yong Tan. Pathological ATPergic Signaling in Major Depression and Bipolar Disorder. Frontiers in molecular neuroscience. vol 12. 2020-09-28. PMID:32076399. |
more recent studies showed that a decrease in the astrocytic release of atp in the prefrontal cortex and hippocampus is a major cause of mood disorders. |
2020-09-28 |
2023-08-13 |
mouse |
| Deblina Dey, Vipan K Parihar, Gergely G Szabo, Peter M Klein, Jenny Tran, Jonathan Moayyad, Faizy Ahmed, Quynh-Anh Nguyen, Alexandria Murry, David Merriott, Brandon Nguyen, Jodi Goldman, Maria C Angulo, Daniele Piomelli, Ivan Soltesz, Janet E Baulch, Charles L Limol. Neurological Impairments in Mice Subjected to Irradiation and Chemotherapy. Radiation research. vol 193. issue 5. 2020-09-14. PMID:32134362. |
relevant to the known roles of the serotonin axis in mood disorders, we found that 5ht1a serotonin receptor levels were decreased by ∼50% in the hippocampus at both early and late time points, and a 37% decrease in serotonin levels was observed at 15 weeks postirradiation. |
2020-09-14 |
2023-08-13 |
mouse |
| P Bielefeld, I Durá, J Danielewicz, P J Lucassen, V Baekelandt, D N Abrous, J M Encinas, C P Fitzsimon. Insult-induced aberrant hippocampal neurogenesis: Functional consequences and possible therapeutic strategies. Behavioural brain research. vol 372. 2020-09-10. PMID:31199935. |
brain pathologies that involve the hippocampus like epilepsy, stroke, and traumatic brain injury, are commonly associated with cognitive impairments and mood disorders. |
2020-09-10 |
2023-08-13 |
Not clear |
| Gin S Malhi, Pritha Das, Tim Outhred, Lauren Irwin, Danielle Gessler, Zina Bwabi, Richard Bryant, Zola Manni. The effects of childhood trauma on adolescent hippocampal subfields. The Australian and New Zealand journal of psychiatry. vol 53. issue 5. 2020-06-15. PMID:30712362. |
the hippocampus is a complex structure comprised of subfields that develop differentially and respond variably to stress and childhood adversity, both of which are risk factors for mood disorders. |
2020-06-15 |
2023-08-13 |
Not clear |
| Gin S Malhi, Pritha Das, Tim Outhred, Lauren Irwin, Danielle Gessler, Zina Bwabi, Richard Bryant, Zola Manni. The effects of childhood trauma on adolescent hippocampal subfields. The Australian and New Zealand journal of psychiatry. vol 53. issue 5. 2020-06-15. PMID:30712362. |
to better understand vulnerability to mood disorders, we investigated a cohort of adolescent girls and determined volumetric changes in their hippocampal subfields to elucidate the potential effects of childhood trauma. |
2020-06-15 |
2023-08-13 |
Not clear |
| Gin S Malhi, Pritha Das, Tim Outhred, Carol Dobson-Stone, Lauren Irwin, Danielle Gessler, Richard Bryant, Zola Manni. Effect of stress gene-by-environment interactions on hippocampal volumes and cortisol secretion in adolescent girls. The Australian and New Zealand journal of psychiatry. vol 53. issue 4. 2020-05-19. PMID:30754992. |
genes interacting with the environment (g × e) are implicated in hypothalamic-pituitary-adrenal axis dysregulation, hippocampal volume changes and risk or resilience to mood disorders. |
2020-05-19 |
2023-08-13 |
Not clear |