| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Heutin. Untangling tau-related dementia. Human molecular genetics. vol 9. issue 6. 2000-05-31. PMID:10767321. |
the recent finding that mutations in the tau gene are responsible for frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) has provided convincing evidence that tau protein plays a key role in neurodegeneration. |
2000-05-31 |
2023-08-12 |
Not clear |
| K Arima, A Kowalska, M Hasegawa, M Mukoyama, R Watanabe, M Kawai, K Takahashi, T Iwatsubo, T Tabira, N Sunohar. Two brothers with frontotemporal dementia and parkinsonism with an N279K mutation of the tau gene. Neurology. vol 54. issue 9. 2000-05-30. PMID:10802785. |
two brothers with frontotemporal dementia and parkinsonism with an n279k mutation of the tau gene. |
2000-05-30 |
2023-08-12 |
Not clear |
| R Oliv. [Genetics of frontotemporal dementia and alterations of the tau gene]. Neurologia (Barcelona, Spain). vol 15 Suppl 1. 2000-04-21. PMID:10723173. |
[genetics of frontotemporal dementia and alterations of the tau gene]. |
2000-04-21 |
2023-08-12 |
Not clear |
| M Yasuda, J Takamatsu, I D'Souza, R A Crowther, T Kawamata, M Hasegawa, H Hasegawa, M G Spillantini, S Tanimukai, P Poorkaj, L Varani, G Varani, T Iwatsubo, M Goedert, D G Schellenberg, C Tanak. A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto) Annals of neurology. vol 47. issue 4. 2000-04-21. PMID:10762152. |
a novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (ftd-kumamoto) exonic and intronic mutations in the tau gene cause familial frontotemporal dementia and parkinsonism linked to chromosome 17. |
2000-04-21 |
2023-08-12 |
Not clear |
| M Yasuda, J Takamatsu, I D'Souza, R A Crowther, T Kawamata, M Hasegawa, H Hasegawa, M G Spillantini, S Tanimukai, P Poorkaj, L Varani, G Varani, T Iwatsubo, M Goedert, D G Schellenberg, C Tanak. A novel mutation at position +12 in the intron following exon 10 of the tau gene in familial frontotemporal dementia (FTD-Kumamoto) Annals of neurology. vol 47. issue 4. 2000-04-21. PMID:10762152. |
here, we describe a new mutation, consisting of a c-to-t transition at position +12 of the intron following exon 10 of the tau gene in the kumamoto pedigree, showing frontotemporal dementia. |
2000-04-21 |
2023-08-12 |
Not clear |
| A Savioz, E Kövari, R Anastasiu, C Rossier, K Saini, C Bouras, G Leub. Search for a mutation in the tau gene in a Swiss family with frontotemporal dementia. Experimental neurology. vol 161. issue 1. 2000-03-23. PMID:10683298. |
search for a mutation in the tau gene in a swiss family with frontotemporal dementia. |
2000-03-23 |
2023-08-12 |
Not clear |
| S Ikegami, A Harada, N Hirokaw. Muscle weakness, hyperactivity, and impairment in fear conditioning in tau-deficient mice. Neuroscience letters. vol 279. issue 3. 2000-03-17. PMID:10688046. |
recently, mutations in the tau gene were found in a hereditary neurodegenerative disease called frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) which exhibits various neurological and neuropathological characteristics including phf-like intracellular tau deposit formation. |
2000-03-17 |
2023-08-12 |
mouse |
| K Furukawa, I D'Souza, C H Crudder, H Onodera, Y Itoyama, P Poorkaj, T D Bird, G D Schellenber. Pro-apoptotic effects of tau mutations in chromosome 17 frontotemporal dementia and parkinsonism. Neuroreport. vol 11. issue 1. 2000-03-16. PMID:10683829. |
pro-apoptotic effects of tau mutations in chromosome 17 frontotemporal dementia and parkinsonism. |
2000-03-16 |
2023-08-12 |
human |
| K Furukawa, I D'Souza, C H Crudder, H Onodera, Y Itoyama, P Poorkaj, T D Bird, G D Schellenber. Pro-apoptotic effects of tau mutations in chromosome 17 frontotemporal dementia and parkinsonism. Neuroreport. vol 11. issue 1. 2000-03-16. PMID:10683829. |
it was recently discovered that mutations of tau cause hereditary frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17). |
2000-03-16 |
2023-08-12 |
human |
| M DeTure, L W Ko, S Yen, P Nacharaju, C Easson, J Lewis, M van Slegtenhorst, M Hutton, S H Ye. Missense tau mutations identified in FTDP-17 have a small effect on tau-microtubule interactions. Brain research. vol 853. issue 1. 2000-03-07. PMID:10627302. |
frontotemporal dementia with parkinsonism linked to chromosome 17 (ftdp-17) is a group of related disorders frequently characterized by the formation of tau inclusions in neurons and glial cells. |
2000-03-07 |
2023-08-12 |
Not clear |
| B Ghetti, J Murrell, M G Spillantin. Mutations in the Tau gene cause frontotemporal dementia. Brain research bulletin. vol 50. issue 5-6. 2000-02-11. PMID:10643489. |
mutations in the tau gene cause frontotemporal dementia. |
2000-02-11 |
2023-08-12 |
Not clear |
| Q S Gao, J Memmott, R Lafyatis, S Stamm, G Screaton, A Andreadi. Complex regulation of tau exon 10, whose missplicing causes frontotemporal dementia. Journal of neurochemistry. vol 74. issue 2. 2000-02-10. PMID:10646499. |
complex regulation of tau exon 10, whose missplicing causes frontotemporal dementia. |
2000-02-10 |
2023-08-12 |
human |
| G Roks, B Dermaut, P Heutink, A Julliams, H Backhovens, M Van de Broeck, S Serneels, A Hofman, C Van Broeckhoven, C M van Duijn, M Crut. Mutation screening of the tau gene in patients with early-onset Alzheimer's disease. Neuroscience letters. vol 277. issue 2. 2000-02-08. PMID:10624829. |
the gene encoding tau (mapt) was recently found mutated in frontotemporal dementia (ftd) and other tauopathies. |
2000-02-08 |
2023-08-12 |
Not clear |
| V Bonifati, M Joosse, D J Nicholl, N Vanacore, P Bennett, P Rizzu, G Fabbrini, R Marconi, C Colosimo, N Locuratolo, F Stocchi, U Bonuccelli, M De Mari, G Wenning, P Vieregge, B Oostra, G Meco, P Heutin. The tau gene in progressive supranuclear palsy: exclusion of mutations in coding exons and exon 10 splice sites, and identification of a new intronic variant of the disease-associated H1 haplotype in Italian cases. Neuroscience letters. vol 274. issue 1. 2000-02-04. PMID:10530520. |
mutations in coding exons or exon 10 5'-splice-site of the gene for microtubule-associated protein tau can cause chromosome 17-linked frontotemporal dementia and parkinsonism (ftdp-17). |
2000-02-04 |
2023-08-12 |
Not clear |
| L Molina, J Touchon, M Herpé, D Lefranc, L Duplan, J P Cristol, R Sabatier, P Vermersch, B Pau, C Mourton-Gille. Tau and apo E in CSF: potential aid for discriminating Alzheimer's disease from other dementias. Neuroreport. vol 10. issue 17. 2000-01-19. PMID:10619631. |
interestingly, a significative decrease of csf tau in patients with frontotemporal dementia was found. |
2000-01-19 |
2023-08-12 |
Not clear |
| M Ingelson, M Blomberg, E Benedikz, L O Wahlund, E Karlsson, E Vanmechelen, L Lannfel. Tau immunoreactivity detected in human plasma, but no obvious increase in dementia. Dementia and geriatric cognitive disorders. vol 10. issue 6. 2000-01-11. PMID:10559557. |
in this study, we investigated the presence of tau in plasma from subjects with alzheimer's disease (n = 16), frontotemporal dementia (n = 10), vascular dementia (n = 16) and from healthy controls (n = 15). |
2000-01-11 |
2023-08-12 |
human |
| T Ishihara, M Hong, B Zhang, Y Nakagawa, M K Lee, J Q Trojanowski, V M Le. Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron. vol 24. issue 3. 2000-01-04. PMID:10595524. |
filamentous tau aggregates are hallmarks of tauopathies, e.g., frontotemporal dementia with parkinsonism linked to chromosome 17 (ftdp-17) and amyotrophic lateral sclerosis/parkinsonism-dementia complex (als/pdc). |
2000-01-04 |
2023-08-12 |
mouse |
| J R Murrell, M G Spillantini, P Zolo, M Guazzelli, M J Smith, M Hasegawa, F Redi, R A Crowther, P Pietrini, B Ghetti, M Goeder. Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits. Journal of neuropathology and experimental neurology. vol 58. issue 12. 1999-12-29. PMID:10604746. |
exonic and intronic mutations in tau cause familial neurodegenerative syndromes characterized by frontotemporal dementia and dysfunction of multiple cortical and subcortical circuits. |
1999-12-29 |
2023-08-12 |
Not clear |
| J R Murrell, M G Spillantini, P Zolo, M Guazzelli, M J Smith, M Hasegawa, F Redi, R A Crowther, P Pietrini, B Ghetti, M Goeder. Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits. Journal of neuropathology and experimental neurology. vol 58. issue 12. 1999-12-29. PMID:10604746. |
most isolated tau filaments were straight and resembled filaments found in alzheimer disease and some frontotemporal dementias with tau mutations. |
1999-12-29 |
2023-08-12 |
Not clear |
| K Spittaels, C Van den Haute, J Van Dorpe, K Bruynseels, K Vandezande, I Laenen, H Geerts, M Mercken, R Sciot, A Van Lommel, R Loos, F Van Leuve. Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. The American journal of pathology. vol 155. issue 6. 1999-12-28. PMID:10595944. |
mutations in the human tau gene cause frontotemporal dementia and parkinsonism linked to chromosome 17. |
1999-12-28 |
2023-08-12 |
mouse |