| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C van Swieten, M Stevens, S M Rosso, P Rizzu, M Joosse, I de Koning, W Kamphorst, R Ravid, M G Spillantini, Niermeijer, P Heutin. Phenotypic variation in hereditary frontotemporal dementia with tau mutations. Annals of neurology. vol 46. issue 4. 1999-12-03. PMID:10514099. |
phenotypic variation in hereditary frontotemporal dementia with tau mutations. |
1999-12-03 |
2023-08-12 |
Not clear |
| J C van Swieten, M Stevens, S M Rosso, P Rizzu, M Joosse, I de Koning, W Kamphorst, R Ravid, M G Spillantini, Niermeijer, P Heutin. Phenotypic variation in hereditary frontotemporal dementia with tau mutations. Annals of neurology. vol 46. issue 4. 1999-12-03. PMID:10514099. |
several mutations in the tau gene have been found in families with hereditary frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (ftdp-17). |
1999-12-03 |
2023-08-12 |
Not clear |
| S Zareparsi, K Wirdefeldt, C E Burgess, J Nutt, P Kramer, M Schalling, H Payam. Exclusion of dominant mutations within the FTDP-17 locus on chromosome 17 for Parkinson's disease. Neuroscience letters. vol 272. issue 2. 1999-11-24. PMID:10507561. |
several neurodegenerative disorders which are collectively called frontotemporal dementia and parkinsonism have been mapped to chromosome 17q and mutations in tau have been identified. |
1999-11-24 |
2023-08-12 |
Not clear |
| A D Sperfeld, M B Collatz, H Baier, M Palmbach, A Storch, J Schwarz, K Tatsch, S Reske, M Joosse, P Heutink, A C Ludolp. FTDP-17: an early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation. Annals of neurology. vol 46. issue 5. 1999-11-24. PMID:10553987. |
recently, mutations in the tau gene on chromosome 17 were found causative for autosomal dominantly inherited frontotemporal dementia and parkinsonism (ftdp-17). |
1999-11-24 |
2023-08-12 |
Not clear |
| A D Sperfeld, M B Collatz, H Baier, M Palmbach, A Storch, J Schwarz, K Tatsch, S Reske, M Joosse, P Heutink, A C Ludolp. FTDP-17: an early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation. Annals of neurology. vol 46. issue 5. 1999-11-24. PMID:10553987. |
the association of this early-onset phenotype with p301s mutation is not entirely consistent with current criteria for the diagnosis of frontotemporal dementias and may encourage the search for tau mutations in diseases similar but not identical to ftdp-17. |
1999-11-24 |
2023-08-12 |
Not clear |
| S H Yen, M Hutton, M DeTure, L W Ko, P Nacharaj. Fibrillogenesis of tau: insights from tau missense mutations in FTDP-17. Brain pathology (Zurich, Switzerland). vol 9. issue 4. 1999-11-16. PMID:10517508. |
frontotemporal dementia and parkinsonism linked to chromosome 17 (ftdp-17) is a neurological disorder associated with tau pathology.tau deposits in ftdp-17 brains consist of polymerized filaments of hyperphosphorylated tau, the morphology of which is determined by the nature of the tau gene mutation observed in each case. |
1999-11-16 |
2023-08-12 |
Not clear |
| H R Morris, A J Lees, N W Woo. Neurofibrillary tangle parkinsonian disorders--tau pathology and tau genetics. Movement disorders : official journal of the Movement Disorder Society. vol 14. issue 5. 1999-11-10. PMID:10495033. |
the recent description of mutation in tau in frontotemporal dementia, and a common variant of tau that predisposes to psp, and the relationship of these changes to the tau protein subgroups offers new insights into the pathogenesis of these disorders. |
1999-11-10 |
2023-08-12 |
Not clear |
| C B Chambers, J M Lee, J C Troncoso, S Reich, N A Mum. Overexpression of four-repeat tau mRNA isoforms in progressive supranuclear palsy but not in Alzheimer's disease. Annals of neurology. vol 46. issue 3. 1999-10-20. PMID:10482263. |
a similar increase in four-repeat tau mrna has been reported for mutations associated with frontotemporal dementia and parkinsonism linked to chromosome 17. |
1999-10-20 |
2023-08-12 |
human |
| A Delacourt. Biochemical and molecular characterization of neurofibrillary degeneration in frontotemporal dementias. Dementia and geriatric cognitive disorders. vol 10 Suppl 1. 1999-10-01. PMID:10436346. |
pathological tau proteins have been analyzed qualitatively and quantitatively in all diseases that may present the clinical symptoms of frontotemporal dementias. |
1999-10-01 |
2023-08-12 |
Not clear |
| A Delacourt. Biochemical and molecular characterization of neurofibrillary degeneration in frontotemporal dementias. Dementia and geriatric cognitive disorders. vol 10 Suppl 1. 1999-10-01. PMID:10436346. |
in frontotemporal dementias non-alzheimer, non-pick (lund and manchester criteria), we did not observe the presence of pathological tau proteins in 2 cases, but a third one presented a particular pattern of tau, with soluble pathological tau in frontotemporal areas. |
1999-10-01 |
2023-08-12 |
Not clear |
| A Delacourt. Biochemical and molecular characterization of neurofibrillary degeneration in frontotemporal dementias. Dementia and geriatric cognitive disorders. vol 10 Suppl 1. 1999-10-01. PMID:10436346. |
in conclusion, the biochemical signature of tau distinguishes four classes of frontotemporal dementia. |
1999-10-01 |
2023-08-12 |
Not clear |
| K C Wilhelmsen, L N Clark, B L Miller, D H Geschwin. Tau mutations in frontotemporal dementia. Dementia and geriatric cognitive disorders. vol 10 Suppl 1. 1999-10-01. PMID:10436349. |
tau mutations in frontotemporal dementia. |
1999-10-01 |
2023-08-12 |
Not clear |
| M B Delisle, J R Murrell, R Richardson, J A Trofatter, O Rascol, X Soulages, M Mohr, P Calvas, B Ghett. A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy. Acta neuropathologica. vol 98. issue 1. 1999-09-24. PMID:10412802. |
recently intronic and exonic mutations in the tau gene have been found to be associated with familial neurodegenerative syndromes characterized not only by a predominantly frontotemporal dementia but also by the presence of neurological signs consistent with the dysfunction of multiple subcortical neuronal circuitries. |
1999-09-24 |
2023-08-12 |
Not clear |
| J Pérez-Tur, L Buée, H R Morris, S C Waring, L Onstead, F Wavrant-De Vrièze, R Crook, V Buée-Scherrer, P R Hof, R C Petersen, P L McGeer, A Delacourte, M Hutton, T Siddique, J E Ahlskog, J Hardy, J C Steel. Neurodegenerative diseases of Guam: analysis of TAU. Neurology. vol 53. issue 2. 1999-09-21. PMID:10430438. |
mutations in the tau gene have been described in families affected by frontotemporal dementia with parkinsonism linked to chromosome 17. |
1999-09-21 |
2023-08-12 |
Not clear |
| N Nukin. [Neuronal cell death--what we can see and what we cannot]. Rinsho shinkeigaku = Clinical neurology. vol 39. issue 1. 1999-09-15. PMID:10377783. |
more recently alpha synuclein accumulates in lewy bodies in parkinson disease and tau protein accumulates in nft of hereditary frontotemporal dementia with tau mutation. |
1999-09-15 |
2023-08-12 |
Not clear |
| H Houlden, M Baker, J Adamson, A Grover, S Waring, D Dickson, T Lynch, B Boeve, R C Petersen, S Pickering-Brown, F Owen, D Neary, D Craufurd, J Snowden, D Mann, M Hutto. Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia. Annals of neurology. vol 46. issue 2. 1999-08-31. PMID:10443890. |
splice-site and missense mutations have been identified in tau associated with frontotemporal dementia with parkinsonism linked to chromosome 17. |
1999-08-31 |
2023-08-12 |
Not clear |
| H Houlden, M Baker, J Adamson, A Grover, S Waring, D Dickson, T Lynch, B Boeve, R C Petersen, S Pickering-Brown, F Owen, D Neary, D Craufurd, J Snowden, D Mann, M Hutto. Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia. Annals of neurology. vol 46. issue 2. 1999-08-31. PMID:10443890. |
comparing the three clinical series: in the stringently diagnosed manchester frontotemporal dementia series, tau mutations were present in 13.6% of cases (three splice-site mutations); in the clinicopathological referral series that used more general inclusion criteria, 3 cases with p301l mutations were observed, which represents a lower mutation frequency of 3.6% (9.4% in familial cases); in contrast, tau mutations were not detected in the minnesota community-based dementia series, suggesting the occurrence of these mutations in dementia generally is rare (<0.2%). |
1999-08-31 |
2023-08-12 |
Not clear |
| L Varani, M Hasegawa, M G Spillantini, M J Smith, J R Murrell, B Ghetti, A Klug, M Goedert, G Varan. Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 14. 1999-08-26. PMID:10393977. |
structure of tau exon 10 splicing regulatory element rna and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. |
1999-08-26 |
2023-08-12 |
Not clear |
| L Varani, M Hasegawa, M G Spillantini, M J Smith, J R Murrell, B Ghetti, A Klug, M Goedert, G Varan. Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 14. 1999-08-26. PMID:10393977. |
coding region and intronic mutations in the tau gene cause frontotemporal dementia and parkinsonism linked to chromosome 17. |
1999-08-26 |
2023-08-12 |
Not clear |
| M Tolnay, A Probs. REVIEW: tau protein pathology in Alzheimer's disease and related disorders. Neuropathology and applied neurobiology. vol 25. issue 3. 1999-08-26. PMID:10417659. |
the impact of the recent finding of tau gene mutations in familial frontotemporal dementia and parkinsonism linked to chromosome 17 on other tauopathies is discussed in the second part. |
1999-08-26 |
2023-08-12 |
Not clear |