| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Iseki, T Matsumura, W Marui, H Hino, T Odawara, N Sugiyama, K Suzuki, H Sawada, T Arai, K Kosak. Familial frontotemporal dementia and parkinsonism with a novel N296H mutation in exon 10 of the tau gene and a widespread tau accumulation in the glial cells. Acta neuropathologica. vol 102. issue 3. 2002-01-24. PMID:11585254. |
we report a 62-year-old japanese man with familial frontotemporal dementia and a novel missense mutation (n296h) in exon 10 of the tau gene. |
2002-01-24 |
2023-08-12 |
Not clear |
| E Iseki, T Matsumura, W Marui, H Hino, T Odawara, N Sugiyama, K Suzuki, H Sawada, T Arai, K Kosak. Familial frontotemporal dementia and parkinsonism with a novel N296H mutation in exon 10 of the tau gene and a widespread tau accumulation in the glial cells. Acta neuropathologica. vol 102. issue 3. 2002-01-24. PMID:11585254. |
these findings suggest that tau proteins are not always assembled in abnormal filaments such as twisted ribbons, paired helical filaments and straight tubules in neurons and glial cells, which have been shown in previous cases with frontotemporal dementia and parkinsonism linked to chromosome 17. |
2002-01-24 |
2023-08-12 |
Not clear |
| M Hutton, J Lewis, D Dickson, S H Yen, E McGowa. Analysis of tauopathies with transgenic mice. Trends in molecular medicine. vol 7. issue 10. 2002-01-09. PMID:11597522. |
a pivotal finding was the identification in 1998 of mutations in tau associated with frontotemporal dementia with parkinsonism linked to chromosome 17. |
2002-01-09 |
2023-08-12 |
mouse |
| R W Berry, B Quinn, N Johnson, E J Cochran, N Ghoshal, L I Binde. Pathological glial tau accumulations in neurodegenerative disease: review and case report. Neurochemistry international. vol 39. issue 5-6. 2001-12-28. PMID:11578782. |
in this report, we summarize the pattern of glial tau pathology in various neurodegenerative disorders and add original findings from a case of sporadic frontotemporal dementia that exhibits astrocytic tau pathology. |
2001-12-28 |
2023-08-12 |
Not clear |
| B Kalbfuss, S A Mabon, T Mistel. Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17. The Journal of biological chemistry. vol 276. issue 46. 2001-12-26. PMID:11560926. |
correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17. |
2001-12-26 |
2023-08-12 |
human |
| B Kalbfuss, S A Mabon, T Mistel. Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17. The Journal of biological chemistry. vol 276. issue 46. 2001-12-26. PMID:11560926. |
mutations in the human tau gene cause frontotemporal dementia and parkinsonism associated with chromosome 17 (ftdp-17). |
2001-12-26 |
2023-08-12 |
human |
| E Adamec, H T Chang, E G Stopa, J C Hedreen, J P Vonsatte. Tau protein expression in frontotemporal dementias. Neuroscience letters. vol 315. issue 1-2. 2001-12-26. PMID:11711205. |
tau protein expression in frontotemporal dementias. |
2001-12-26 |
2023-08-12 |
Not clear |
| M Goedert, M G Spillantin. Tau gene mutations and neurodegeneration. Biochemical Society symposium. issue 67. 2001-12-14. PMID:11447840. |
filamentous tau protein deposits are also the defining neuropathological characteristic of other neurodegenerative diseases, many of which are frontotemporal dementias or movement disorders, such as pick's disease, progressive supranuclear palsy and corticobasal degeneration. |
2001-12-14 |
2023-08-12 |
Not clear |
| M Goedert, M G Spillantin. Tau gene mutations and neurodegeneration. Biochemical Society symposium. issue 67. 2001-12-14. PMID:11447840. |
this has now changed with the discovery of close to 20 mutations in the tau gene in frontotemporal dementia with parkinsonism linked to chromosome 17. |
2001-12-14 |
2023-08-12 |
Not clear |
| J P Brion, B H Anderton, M Authelet, R Dayanandan, K Leroy, S Lovestone, J N Octave, L Pradier, N Touchet, G Trem. Neurofibrillary tangles and tau phosphorylation. Biochemical Society symposium. issue 67. 2001-12-14. PMID:11447842. |
in transfected cells, mutated tau forms (corresponding to tau mutations identified in familial forms of frontotemporal dementias linked to chromosome 17) were less efficient in their ability to sustain microtubule growth. |
2001-12-14 |
2023-08-12 |
mouse |
| K Miyamoto, A Kowalska, M Hasegawa, T Tabira, K Takahashi, W Araki, I Akiguchi, A Ikemot. Familial frontotemporal dementia and parkinsonism with a novel mutation at an intron 10+11-splice site in the tau gene. Annals of neurology. vol 50. issue 1. 2001-12-14. PMID:11456301. |
familial frontotemporal dementia and parkinsonism with a novel mutation at an intron 10+11-splice site in the tau gene. |
2001-12-14 |
2023-08-12 |
Not clear |
| P Poorkaj, D Tsuang, E Wijsman, E Steinbart, R M Garruto, U K Craig, N H Chapman, L Anderson, T D Bird, C C Plato, D P Perl, W Weiderholt, D Galasko, G D Schellenber. TAU as a susceptibility gene for amyotropic lateral sclerosis-parkinsonism dementia complex of Guam. Archives of neurology. vol 58. issue 11. 2001-12-07. PMID:11708997. |
because neurofibrillary tangles containing tau protein are present in als-g-pdc-g, and because mutations in the tau gene (tau) cause autosomal dominant frontotemporal dementia, tau was examined as a candidate gene for als-g-pdc-g. |
2001-12-07 |
2023-08-12 |
Not clear |
| A Kowalska, T Asada, K Arima, C Kumakiri, W Kozubski, K Takahashi, T Tabir. Genetic analysis in patients with familial and sporadic frontotemporal dementia: two tau mutations in only familial cases and no association with apolipoprotein epsilon4. Dementia and geriatric cognitive disorders. vol 12. issue 6. 2001-12-05. PMID:11598310. |
genetic analysis in patients with familial and sporadic frontotemporal dementia: two tau mutations in only familial cases and no association with apolipoprotein epsilon4. |
2001-12-05 |
2023-08-12 |
human |
| A Kowalska, T Asada, K Arima, C Kumakiri, W Kozubski, K Takahashi, T Tabir. Genetic analysis in patients with familial and sporadic frontotemporal dementia: two tau mutations in only familial cases and no association with apolipoprotein epsilon4. Dementia and geriatric cognitive disorders. vol 12. issue 6. 2001-12-05. PMID:11598310. |
we screened for tau gene mutations among 24 japanese (6 familial and 18 sporadic cases) and 4 polish patients with frontotemporal dementia (ftd) using pcr-sscp analysis followed by dna sequencing. |
2001-12-05 |
2023-08-12 |
human |
| R de Silva, M Weiler, H R Morris, E R Martin, N W Wood, A J Lee. Strong association of a novel Tau promoter haplotype in progressive supranuclear palsy. Neuroscience letters. vol 311. issue 3. 2001-12-04. PMID:11578815. |
mutations in the tau gene in frontotemporal dementia with parkinsonism linked to chromosome 17 (ftdp-17) and genetic association of the h1 haplotype of the tau gene with psp has firmly established a direct role for tau in disease pathogenesis. |
2001-12-04 |
2023-08-12 |
Not clear |
| M Goeder. The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases. Current opinion in genetics & development. vol 11. issue 3. 2001-11-01. PMID:11377973. |
mutations in the tau gene in familial forms of frontotemporal dementia and in the alpha-synuclein gene in familial cases of parkinson's disease have provided causal links between the dysfunction of these proteins and neurodegeneration. |
2001-11-01 |
2023-08-12 |
Not clear |
| M Goeder. The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases. Current opinion in genetics & development. vol 11. issue 3. 2001-11-01. PMID:11377973. |
over the past year, several novel tau gene mutations have been identified and more has been learned about possible mechanisms by which tau gene mutations lead to frontotemporal dementia. |
2001-11-01 |
2023-08-12 |
Not clear |
| S M Rosso, W Kamphorst, B de Graaf, R Willemsen, R Ravid, M F Niermeijer, M G Spillantini, P Heutink, J C van Swiete. Familial frontotemporal dementia with ubiquitin-positive inclusions is linked to chromosome 17q21-22. Brain : a journal of neurology. vol 124. issue Pt 10. 2001-11-01. PMID:11571213. |
hereditary frontotemporal dementia (ftd) is an autosomal dominant neurodegenerative disorder that is associated with mutations in the tau gene and with the pathological accumulation of hyperphosphorylated tau protein in affected brain cells in about a quarter of cases. |
2001-11-01 |
2023-08-12 |
Not clear |
| M Neumann, W Schulz-Schaeffer, R A Crowther, M J Smith, M G Spillantini, M Goedert, H A Kretzschma. Pick's disease associated with the novel Tau gene mutation K369I. Annals of neurology. vol 50. issue 4. 2001-11-01. PMID:11601501. |
exonic and intronic mutations in tau cause neurodegenerative syndromes characterized by frontotemporal dementia and filamentous tau protein deposits. |
2001-11-01 |
2023-08-12 |
Not clear |
| M G Spillantini, M Goeder. Tau gene mutations and tau pathology in frontotemporal dementia and parkinsonism linked to chromosome 17. Advances in experimental medicine and biology. vol 487. 2001-10-25. PMID:11403160. |
tau gene mutations and tau pathology in frontotemporal dementia and parkinsonism linked to chromosome 17. |
2001-10-25 |
2023-08-12 |
Not clear |