| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Dimitrova, T Chernev, I Kremenski, V Mazneĭkova, E Mikhaĭlova, E Simeonov, R Tincheva, D Tonchev. [Second trimester Down syndrome serum screening--results from a pilot study]. Akusherstvo i ginekologiia. vol 41. issue 2. 2002-08-15. PMID:12066548. |
the results from a pilot prospective study--second trimester down syndrome [ds] serum screening between 15 and 21 w.g. |
2002-08-15 |
2023-08-12 |
Not clear |
| Seong Hwan Kim, Ki Shuk Shim, Gert Lube. Human brain nascent polypeptide-associated complex alpha subunit is decreased in patients with Alzheimer' s disease and Down syndrome. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. vol 50. issue 4. 2002-08-12. PMID:12109594. |
performing gene hunting using differential display-polymerase chain reaction, a downregulated sequence in the frontal cortex of patients with alzheimer's disease (ad) and down syndrome (ds) with ad-like neuropathology was identified as a-nac with 100% homology. |
2002-08-12 |
2023-08-12 |
human |
| Paulo Alves Junqueira, Maria Valeriana L de Moura-Ribeir. [Moyamoya and Down syndrome: study conducted by meta-analysis]. Arquivos de neuro-psiquiatria. vol 60. issue 2-A. 2002-08-09. PMID:12068359. |
we present a clinic-epidemiological study of two patients and meta-analysis (period 1977-2000 ) of the co-morbidity of the down syndrome (ds) and moyamoya syndrome (mms). |
2002-08-09 |
2023-08-12 |
Not clear |
| Ryuichi Nishigaki, Tokuyuki Shinohara, Tosifusa Toda, Akira Omori, Sachiyo Ichinose, Masayuki Itoh, Yasuaki Shirayoshi, Akihiro Kurimasa, Mitsuo Oshimur. An extra human chromosome 21 reduces mlc-2a expression in chimeric mice and Down syndrome. Biochemical and biophysical research communications. vol 295. issue 1. 2002-08-09. PMID:12083776. |
an extra copy of human chromosome 21 (chr 21) causes down syndrome (ds), which is characterized by mental retardation and congenital heart disease (chd). |
2002-08-09 |
2023-08-12 |
mouse |
| Ki Shuk Shim, Gert Lube. Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome. Neuroscience letters. vol 324. issue 3. 2002-08-07. PMID:12009525. |
although drebrin regulates the morphological changes of spines in neurodegenerative disease such as alzheimer's disease (ad), drebrin in down syndrome (ds) showing ad-like neuropathology has not been studied. |
2002-08-07 |
2023-08-12 |
Not clear |
| O Katsuse, E Iseki, K Suzuki, K Kosak. Frequency and distribution of TUNEL-positive neurons in brains of dementia with Lewy bodies: comparison with those in brains of Alzheimer's disease. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 21. issue 4. 2002-08-06. PMID:11837533. |
the present study investigated the frequency and distribution of tunel-positive neurons in brains of dementia with lewy bodies (dlb) in comparison with those in brains of alzheimer's disease (ad), down syndrome (ds) and non-demented elderly persons. |
2002-08-06 |
2023-08-12 |
Not clear |
| Wendy R Kates, Bradley S Folley, Diane C Lanham, George T Capone, Walter E Kaufman. Cerebral growth in Fragile X syndrome: review and comparison with Down syndrome. Microscopy research and technique. vol 57. issue 3. 2002-08-06. PMID:12112452. |
the present study attempted to examine cerebral and lobar-level volumetric changes in young males with frax (2-7 years), by comparing groups of subjects with full mutation (fm) and mosaicism (mos) with both age-matched controls and subjects with developmental language delay (dld) and down syndrome (ds). |
2002-08-06 |
2023-08-12 |
human |
| Yasuhiro Arai, Takeshi Ijuin, Tadanomi Takenawa, Laurence E Becker, Sachio Takashim. Excessive expression of synaptojanin in brains with Down syndrome. Brain & development. vol 24. issue 2. 2002-07-31. PMID:11891094. |
we investigated the expression of synaptojanin, which has been mapped on 21q22.2 on human chromosome, in the cerebral cortex of patients with down syndrome (ds), using immunohistochemistry and immunoblotting. |
2002-07-31 |
2023-08-12 |
human |
| S Chaushu, E Yefenof, A Becker, J Shapira, G Chaush. Severe impairment of secretory Ig production in parotid saliva of Down Syndrome individuals. Journal of dental research. vol 81. issue 5. 2002-07-25. PMID:12097442. |
infections associated with down syndrome (ds) are prevalent in the mucosal-gastrointestinal and respiratory systems, for reasons that are uncertain. |
2002-07-25 |
2023-08-12 |
human |
| E Engidawork, G Lube. Protein expression in Down syndrome brain. Amino acids. vol 21. issue 4. 2002-07-24. PMID:11858695. |
down syndrome (ds) is the most common chromosomal abnormality associated with early mental retardation and neurological abnormalities followed by precocious age dependent alzheimer-type neurode generation later in life. |
2002-07-24 |
2023-08-12 |
Not clear |
| Rachel Weitzdoerfer, Michael Fountoulakis, Gert Lube. Reduction of actin-related protein complex 2/3 in fetal Down syndrome brain. Biochemical and biophysical research communications. vol 293. issue 2. 2002-07-12. PMID:12054546. |
down syndrome (ds) patients present with morphological abnormalities in brain development, leading to mental retardation. |
2002-07-12 |
2023-08-12 |
Not clear |
| Erzsébet Balogh, Zsolt Lengyel, Miklós Emri, Edit Szikszai, Olga Esik, József Kollár, Judit Sikula, Lajos Trón, Eva Olá. [Cerebral glucose metabolism in Down syndrome using positron emission tomography]. Orvosi hetilap. vol 143. issue 21 Suppl 3. 2002-07-10. PMID:12077923. |
resting cerebral glucose metabolism was assessed by pet using fdg in eleven down syndrome (ds) patients. |
2002-07-10 |
2023-08-12 |
Not clear |
| N V Kovaleva, I V Butom. [Reproductive behavior and Down syndrome]. TSitologiia i genetika. vol 36. issue 1. 2002-06-27. PMID:12012598. |
coital rates and contraception practice were investigated in mothers of 160 newborns with down syndrome (ds) in comparison with the same aged (+/- 1 year) mothers of 160 healthy newborns. |
2002-06-27 |
2023-08-12 |
Not clear |
| Joan T Richtsmeier, Ann Zumwalt, Elaine J Carlson, Charles J Epstein, Roger H Reeve. Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome. American journal of medical genetics. vol 107. issue 4. 2002-06-26. PMID:11840489. |
trisomy for chromosome 21 (chr 21) has profound effects on development that result in a constellation of phenotypes known as down syndrome (ds). |
2002-06-26 |
2023-08-12 |
mouse |
| John R Atack, Mark B Schapir. Inositol monophosphatase activity in normal, Down syndrome and dementia of the Alzheimer type CSF. Neurobiology of aging. vol 23. issue 3. 2002-06-14. PMID:11959401. |
since levels of inositol have been previously reported to be elevated in down syndrome (ds) csf, impase activity was measured in csf of ds subjects to establish whether altered inositol levels may be related to changes in impase activity. |
2002-06-14 |
2023-08-12 |
human |
| Roxana Cerretini, Susana Acevedo, Christian Chena, Carolina Belli, Irene Larripa, Irma Slavutsk. Evaluation of constitutional chromosome aberrations in hematologic disorders. Cancer genetics and cytogenetics. vol 134. issue 2. 2002-06-14. PMID:12034526. |
they included four patients with robertsonian translocations, one patient with a balanced translocation, two patients with sex chromosome abnormalities, and 17 cases with down syndrome (ds). |
2002-06-14 |
2023-08-12 |
Not clear |
| S H Kim, G Lube. Decreased alpha-endosulfine, an endogenous regulator of ATP-sensitive potassium channels, in brains from adult Down syndrome patients. Journal of neural transmission. Supplementum. issue 61. 2002-06-10. PMID:11771735. |
we examined the expression levels of alpha-endosulfine protein in frontal cortex and cerebellum from patients with down syndrome (ds) showing alzheimer's disease (ad) pathology using western blotting. |
2002-06-10 |
2023-08-12 |
Not clear |
| S H Kim, M Fountoulakis, M Dierssen, G Lube. Decreased protein levels of complex I 30-kDa subunit in fetal Down syndrome brains. Journal of neural transmission. Supplementum. issue 61. 2002-06-10. PMID:11771736. |
in previous work, we reported decreased protein levels of mitochondrial electron transport enzyme subunits in adult brain with down syndrome (ds). |
2002-06-10 |
2023-08-12 |
Not clear |
| B L Shapir. Developmental instability of the cerebellum and its relevance to Down syndrome. Journal of neural transmission. Supplementum. issue 61. 2002-06-10. PMID:11771737. |
it has been recognized for many years that cerebellar abnormalities are frequently observed in association with down syndrome (ds). |
2002-06-10 |
2023-08-12 |
mouse |
| E Engidawork, J F Juranville, M Fountoulakis, M Dierssen, G Lube. Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome. Journal of neural transmission. Supplementum. issue 61. 2002-06-10. PMID:11771738. |
fetal down syndrome (ds) neurons were demonstrated to degenerate and undergo apoptosis in vitro. |
2002-06-10 |
2023-08-12 |
Not clear |