| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Dierssen, C Fillat, L Crnic, M Arbonés, J Flórez, X Estivil. Murine models for Down syndrome. Physiology & behavior. vol 73. issue 5. 2001-12-04. PMID:11566219. |
the availability of the recently published dna sequence of human chromosome 21 (hsa21) is a landmark contribution that will have an immediate impact on the study of the role of specific genes to down syndrome (ds). |
2001-12-04 |
2023-08-12 |
mouse |
| E Sanij, T Hatzistavrou, P Hertzog, I Kola, E J Wolvetan. Ets-2 is induced by oxidative stress and sensitizes cells to H(2)O(2)-induced apoptosis: implications for Down's syndrome. Biochemical and biophysical research communications. vol 287. issue 4. 2001-12-04. PMID:11573964. |
here we show that ets-2, a transcription factor located on human chromosome 21 and already overexpressed in multiple tissues in down syndrome (ds, trisomy 21), is induced by low concentrations of hydrogen peroxide. |
2001-12-04 |
2023-08-12 |
human |
| B Fernhall, J A McCubbin, K H Pitetti, P Rintala, J H Rimmer, A L Millar, A De Silv. Prediction of maximal heart rate in individuals with mental retardation. Medicine and science in sports and exercise. vol 33. issue 10. 2001-12-04. PMID:11581548. |
it is well known that individuals with mental retardation (mr), especially those with down syndrome (ds), have low maximal heart rates (mhr). |
2001-12-04 |
2023-08-12 |
Not clear |
| L D Nelson, D Orme, K Osann, I T Lot. Neurological changes and emotional functioning in adults with Down Syndrome. Journal of intellectual disability research : JIDR. vol 45. issue Pt 5. 2001-12-04. PMID:11679050. |
this study was designed to examine emotional changes in adults with down syndrome (ds) over time and whether changes in these psychological variables were associated with brain atrophy on mri scan and the presence of pathological reflexes on the neurological examination. |
2001-12-04 |
2023-08-12 |
human |
| A G Durmowic. Pulmonary edema in 6 children with Down syndrome during travel to moderate altitudes. Pediatrics. vol 108. issue 2. 2001-10-25. PMID:11483813. |
children with down syndrome (ds) are living longer and are increasingly participating in recreational activities. |
2001-10-25 |
2023-08-12 |
Not clear |
| S O Larsen, J Hansen, B N Pederse. Expected, prenatally discovered, and born cases of Down syndrome in Denmark during the period 1980-1998. Prenatal diagnosis. vol 21. issue 8. 2001-10-25. PMID:11536260. |
in order to elucidate the consistency between generally used age-dependent risk values for down syndrome (ds) and estimates of the probability of miscarriage in down pregnancies we have compared expected numbers with estimated numbers of births with ds in denmark had no intervention at all been carried out. |
2001-10-25 |
2023-08-12 |
Not clear |
| L S Barenfel'd, S G Nergadze, V M Mikhel'so. [Decreased frequency of activation of replicon clusters in Down syndrome lymphocytes]. Tsitologiia. vol 43. issue 7. 2001-10-25. PMID:11552652. |
human blood lymphocytes from two normal and seven down syndrome (ds) subjects were examined to determine rates of synthesis of individual replicon and adjacent clusters of replicons, using dna fiber autoradiography. |
2001-10-25 |
2023-08-12 |
human |
| A D Carothers, E E Castilla, M G Dutra, E B Hoo. Search for ethnic, geographic, and other factors in the epidemiology of Down syndrome in South America: analysis of data from the ECLAMC project, 1967-1997. American journal of medical genetics. vol 103. issue 2. 2001-10-25. PMID:11568922. |
we have analyzed data on 3,157 cases of down syndrome (ds) from nine south american countries in consecutive series of hospital live births over a 30-year period, with particular emphasis on possible ethnic or geographic variations in maternal age-adjusted incidence. |
2001-10-25 |
2023-08-12 |
human |
| N Schupf, D Kapell, B Nightingale, J H Lee, J Mohlenhoff, S Bewley, R Ottman, R Mayeu. Specificity of the fivefold increase in AD in mothers of adults with Down syndrome. Neurology. vol 57. issue 6. 2001-10-18. PMID:11571320. |
in a previous study, the authors found that the risk of ad among mothers who were 35 years or younger when their children with down syndrome (ds) were born was five times that of mothers of children with other forms of mental retardation. |
2001-10-18 |
2023-08-12 |
Not clear |
| J Mackey, W R Treem, G Worley, A Boney, P Hart, P S Kishnan. Frequency of celiac disease in individuals with Down syndrome in the United States. Clinical pediatrics. vol 40. issue 5. 2001-10-11. PMID:11388673. |
ninety-three individuals with down syndrome (ds) were screened to investigate the prevalence of celiac disease (cd) in the united states. |
2001-10-11 |
2023-08-12 |
Not clear |
| E Bell, G Townsend, D Wilson, J Kieser, T Hughe. Effect of Down syndrome on the dimensions of dental crowns and tissues. American journal of human biology : the official journal of the Human Biology Council. vol 13. issue 5. 2001-10-11. PMID:11505477. |
abnormal growth in down syndrome (ds) is reflected by variable reduction in size and simplification in form of many physical traits. |
2001-10-11 |
2023-08-12 |
Not clear |
| B Lubec, R Weitzdoerfer, M Fountoulaki. Manifold reduction of moesin in fetal Down syndrome brain. Biochemical and biophysical research communications. vol 286. issue 5. 2001-10-11. PMID:11527426. |
because moesin was shown to be highly expressed in growth cones and moesin/radixin suppression led to impaired structure and function of this key element in brain development, we tested the erm family, ezrin, radixin, and moesin, in fetal down syndrome (ds) cortex at the early second trimester. |
2001-10-11 |
2023-08-12 |
Not clear |
| C J Forster-Gibson, J Davies, J J MacKenzie, K Harriso. Cryptic duplication of 21q in an individual with a clinical diagnosis of Down syndrome. Clinical genetics. vol 59. issue 6. 2001-10-04. PMID:11453976. |
we describe an adult male who was diagnosed with down syndrome (ds) at 9 months of age, but had repeatedly normal karyotypes until recent mid-resolution chromosome studies showed a possible duplication of 21q22.13 to 21q22.3. |
2001-10-04 |
2023-08-12 |
Not clear |
| Y Ochshorn, M J Kupferminc, I Wolman, A Orr-Urtreger, A J Jaffa, Y Yaro. First trimester PAPP-A in the detection of non-Down syndrome aneuploidy. Prenatal diagnosis. vol 21. issue 7. 2001-10-04. PMID:11494288. |
combined first trimester screening using pregnancy associated plasma protein-a (papp-a), free beta-human chorionic gonadotrophin, and nuchal translucency (nt), is currently accepted as probably the best combination for the detection of down syndrome (ds). |
2001-10-04 |
2023-08-12 |
Not clear |
| K R Wøjdemann, S O Larsen, A Shalmi, K Sundberg, M Christiansen, A Tabo. First trimester screening for Down syndrome and assisted reproduction: no basis for concern. Prenatal diagnosis. vol 21. issue 7. 2001-10-04. PMID:11494292. |
in pregnancies obtained after assisted reproduction the false-positive rate of second trimester down syndrome (ds) screening is increased by 1.5-3-fold. |
2001-10-04 |
2023-08-12 |
Not clear |
| A Panchón-Ruiz, V Jornet-Carrillo, F Sanchez del Camp. Palate vault morphology in Down syndrome. Journal of craniofacial genetics and developmental biology. vol 20. issue 4. 2001-09-27. PMID:11354516. |
moire topography was used to quantitatively determine the shape of the palatal vault in 57 spanish patients with down syndrome (ds) (38 males and 19 females; age range 18-36 years) and in 100 normal controls (n) (76 males and 24 females; age range 20-29 years). |
2001-09-27 |
2023-08-12 |
human |
| K Carlstedt, G Henningsson, A McAllister, G Dahllö. Long-term effects of palatal plate therapy on oral motor function in children with Down syndrome evaluated by video registration. Acta odontologica Scandinavica. vol 59. issue 2. 2001-09-27. PMID:11370751. |
oral motor function was evaluated after 4 years of palatal plate therapy in nine children with down syndrome (ds); 11 children with ds constituted the control group. |
2001-09-27 |
2023-08-12 |
Not clear |
| M S Cheon, M Bajo, T Gulesserian, N Cairns, G Lube. Evidence for the relation of herpes simplex virus type 1 to Down syndrome and Alzheimer's disease. Electrophoresis. vol 22. issue 3. 2001-09-13. PMID:11258753. |
we tested whether the hsv-1 genome is found indeed in the brain of controls, patients with ad and down syndrome (ds) and whether hsv-1 infectious proteins in brain were induced. |
2001-09-13 |
2023-08-12 |
human |
| D K Choi, Y Suzuki, S Yoshimura, T Togashi, M Hida, T D Taylor, Y Wang, S Sugano, M Hattori, Y Sakak. Molecular cloning and characterization of a gene expressed in mouse developing tongue, mDscr5 gene, a homolog of human DSCR5 (Down syndrome Critical Region gene 5). Mammalian genome : official journal of the International Mammalian Genome Society. vol 12. issue 5. 2001-09-06. PMID:11331941. |
for understanding the pathogenesis of down syndrome (ds), it is important to identify and characterize the genes on chromosome (chr) 21, especially those in the down syndrome critical region (dscr) on chr 21q22.2. |
2001-09-06 |
2023-08-12 |
mouse |
| R Vlkolinský, N Cairns, M Fountoulakis, G Lube. Decreased brain levels of 2',3'-cyclic nucleotide-3'-phosphodiesterase in Down syndrome and Alzheimer's disease. Neurobiology of aging. vol 22. issue 4. 2001-08-30. PMID:11445254. |
in down syndrome (ds) as well as in alzheimer's disease (ad) oligodendroglial and myelin alterations have been reported. |
2001-08-30 |
2023-08-12 |
Not clear |