| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Jadranka Vranekovi\\xc4\\x87, Ivana Babi\\xc4\\x87 Bozovi\\xc4\\x87, Nada Starcevi\\xc4\\x87 Cizmarevi\\xc4\\x87, Alena Bureti\\xc4\\x87-Tomljanovi\\xc4\\x87, Smiljana Risti\\xc4\\x87, Oleg Petrovi\\xc4\\x87, Miljenko Kapovi\\xc4\\x87, Bojana Brajenovi\\xc4\\x87-Mili\\xc4\\x8. Functional inference of methylenetetrahydrofolate reductase gene polymorphisms on enzyme stability as a potential risk factor for Down syndrome in Croatia. Disease markers. vol 28. issue 5. 2010-10-05. PMID:20592453.' |
understanding the biochemical structure and function of the methylenetetrahydrofolate reductase gene (mthfr) provides new evidence in elucidating the risk of having a child with down syndrome (ds) in association with two common mthfr polymorphisms, c677t and a1298c. |
2010-10-05 |
2023-08-12 |
Not clear |
| G Albertini, S Bonassi, V Dall'Armi, I Giachetti, S Giaquinto, M Mignan. Spectral analysis of the voice in Down Syndrome. Research in developmental disabilities. vol 31. issue 5. 2010-09-30. PMID:20488659. |
the voice quality of individuals with down syndrome (ds) is generally described as husky, monotonous and raucous. |
2010-09-30 |
2023-08-12 |
human |
| Joshua D Blazek, Cherie N Billingsley, Abby Newbauer, Randall J Rope. Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome. Developmental dynamics : an official publication of the American Association of Anatomists. vol 239. issue 6. 2010-09-30. PMID:20503361. |
trisomy 21 results in down syndrome (ds) and causes phenotypes that may result from alterations of developmental processes. |
2010-09-30 |
2023-08-12 |
mouse |
| Jisook Moon, May Chen, Shruti U Gandhy, Myla Strawderman, David A Levitsky, Kenneth N Maclean, Barbara J Strup. Perinatal choline supplementation improves cognitive functioning and emotion regulation in the Ts65Dn mouse model of Down syndrome. Behavioral neuroscience. vol 124. issue 3. 2010-09-30. PMID:20528079. |
in addition to mental retardation, individuals with down syndrome (ds) also develop the neuropathological changes typical of alzheimer's disease (ad) and the majority of these individuals exhibit dementia. |
2010-09-30 |
2023-08-12 |
mouse |
| Jamie O Edgin, Bruce F Pennington, Carolyn B Mervi. Neuropsychological components of intellectual disability: the contributions of immediate, working, and associative memory. Journal of intellectual disability research : JIDR. vol 54. issue 5. 2010-09-30. PMID:20537047. |
down syndrome (ds) and williams syndrome (ws)] allows us to test whether or not these dissociations may extend across cognitive domains, including pfc and hippocampal memory processes. |
2010-09-30 |
2023-08-12 |
Not clear |
| Sunjay Suri, Bryan D Tompson, Lynn Cornfoo. Cranial base, maxillary and mandibular morphology in Down syndrome. The Angle orthodontist. vol 80. issue 5. 2010-09-30. PMID:20578856. |
to test the null hypothesis that there is no difference between craniofacial measurements of individuals with down syndrome (ds) and normal controls. |
2010-09-30 |
2023-08-12 |
Not clear |
| Jianhua Wu, Julia Looper, Dale A Ulrich, Rosa M Angulo-Barros. Effects of various treadmill interventions on the development of joint kinematics in infants with Down syndrome. Physical therapy. vol 90. issue 9. 2010-09-30. PMID:20651010. |
infants with down syndrome (ds) have delayed walking and produce less-coordinated walking patterns. |
2010-09-30 |
2023-08-12 |
Not clear |
| Emanuele Leoncini, Lorenzo D Botto, Guido Cocchi, Goran Annerén, Carol Bower, Jane Halliday, Emmanuelle Amar, Marian K Bakker, Sebastiano Bianca, Maria Aurora Canessa Tapia, Eduardo E Castilla, Melinda Csáky-Szunyogh, Saeed Dastgiri, Marcia L Feldkamp, Miriam Gatt, Fumiki Hirahara, Danielle Landau, R Brian Lowry, Lisa Marengo, Robert McDonnell, Triphti M Mathew, Margery Morgan, Osvaldo M Mutchinick, Anna Pierini, Simone Poetzsch, Annukka Ritvanen, Gioacchino Scarano, Csaba Siffel, Antonin Sípek, Elena Szabova, Giovanna Tagliabue, Stein Emil Vollset, Wladimir Wertelecki, Ludmila Zhuchenko, Pierpaolo Mastroiacov. How valid are the rates of Down syndrome internationally? Findings from the International Clearinghouse for Birth Defects Surveillance and Research. American journal of medical genetics. Part A. vol 152A. issue 7. 2010-09-29. PMID:20578135. |
rates of down syndrome (ds) show considerable international variation, but a systematic assessment of this variation is lacking. |
2010-09-29 |
2023-08-12 |
Not clear |
| Tao Yu, Zhongyou Li, Zhengping Jia, Steven J Clapcote, Chunhong Liu, Shaomin Li, Suhail Asrar, Annie Pao, Rongqing Chen, Ni Fan, Sandra Carattini-Rivera, Allison R Bechard, Shoshana Spring, R Mark Henkelman, George Stoica, Sei-Ichi Matsui, Norma J Nowak, John C Roder, Chu Chen, Allan Bradley, Y Eugene Y. A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions. Human molecular genetics. vol 19. issue 14. 2010-09-28. PMID:20442137. |
down syndrome (ds) is caused by the presence of an extra copy of human chromosome 21 (hsa21) and is the most common genetic cause for developmental cognitive disability. |
2010-09-28 |
2023-08-12 |
mouse |
| Kelly W Maloney, William L Carroll, Andrew J Carroll, Meenakshi Devidas, Michael J Borowitz, Paul L Martin, Jeanette Pullen, James A Whitlock, Cheryl L Willman, Naomi J Winick, Bruce M Camitta, Stephen P Hunge. Down syndrome childhood acute lymphoblastic leukemia has a unique spectrum of sentinel cytogenetic lesions that influences treatment outcome: a report from the Children's Oncology Group. Blood. vol 116. issue 7. 2010-09-28. PMID:20442364. |
children with down syndrome (ds) have an increased risk of acute lymphoblastic leukemia (all) and an inferior outcome. |
2010-09-28 |
2023-08-12 |
Not clear |
| Ahmed Khocht, Malvin Janal, Bobby Turne. Periodontal health in Down syndrome: contributions of mental disability, personal, and professional dental care. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. vol 30. issue 3. 2010-09-28. PMID:20500707. |
fifty-five dentate patients with down syndrome (ds) and 74 with mental disability non-down (mr) were compared to 88 control subjects. |
2010-09-28 |
2023-08-12 |
human |
| Esti Davidovich, Doron Jaacob Aframian, Josef Shapira, Benjamin Peret. A comparison of the sialochemistry, oral pH, and oral health status of Down syndrome children to healthy children. International journal of paediatric dentistry. vol 20. issue 4. 2010-09-28. PMID:20536584. |
the aetiology of low caries incidence in down syndrome (ds) children is not entirely clear. |
2010-09-28 |
2023-08-12 |
Not clear |
| Orli Megged, Yechiel Schlesinge. Down syndrome and respiratory syncytial virus infection. The Pediatric infectious disease journal. vol 29. issue 7. 2010-09-24. PMID:20228692. |
we reviewed the medical records of all children with down syndrome (ds), hospitalized in our medical center due to infection with respiratory syncytial virus. |
2010-09-24 |
2023-08-12 |
Not clear |
| Rute M Cerqueira, Cristina M Rocha, Carolina D Fernandes, Manuel R Correi. Celiac disease in Portuguese children and adults with Down syndrome. European journal of gastroenterology & hepatology. vol 22. issue 7. 2010-09-20. PMID:20545028. |
studies from several countries reported higher prevalence rates in down syndrome (ds) patients. |
2010-09-20 |
2023-08-12 |
Not clear |
| Dennis Rose. Severe hypothyroidism presenting as obstructive sleep apnea. Clinical pediatrics. vol 49. issue 4. 2010-09-17. PMID:20118082. |
a 5-year-old child with down syndrome (ds) diagnosed with mild to moderate obstructive sleep apnea (osa) and subsequently found to have severe hypothyroidism is presented. |
2010-09-17 |
2023-08-12 |
Not clear |
| Erika Cristina Pavarino Bertelli, Joice Matos Biselli, Daiana Bonfim, Eny Maria Goloni-Bertoll. Clinical profile of children with Down syndrome treated in a genetics outpatient service in the southeast of Brazil. Revista da Associacao Medica Brasileira (1992). vol 55. issue 5. 2010-09-16. PMID:19918654. |
considering that studies about the frequencies of phenotypic features of down syndrome (ds) in the brazilian population with large ethnic variability are scarce in literature, this study analyzed clinical and demographic characteristics of ds children from the southeastern region of brazil. |
2010-09-16 |
2023-08-12 |
Not clear |
| Pinar E Coskun, Joanne Wyrembak, Olga Derbereva, Goar Melkonian, Eric Doran, Ira T Lott, Elizabeth Head, Carl W Cotman, Douglas C Wallac. Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia. Journal of Alzheimer's disease : JAD. vol 20 Suppl 2. 2010-09-13. PMID:20463402. |
an ad-like dementia is also common in older individuals with down syndrome (ds), though with a much earlier onset. |
2010-09-13 |
2023-08-12 |
Not clear |
| Juliet A Moncaster, Roberto Pineda, Robert D Moir, Suqian Lu, Mark A Burton, Joy G Ghosh, Maria Ericsson, Stephanie J Soscia, Anca Mocofanescu, Rebecca D Folkerth, Richard M Robb, Jer R Kuszak, John I Clark, Rudolph E Tanzi, David G Hunter, Lee E Goldstei. Alzheimer's disease amyloid-beta links lens and brain pathology in Down syndrome. PloS one. vol 5. issue 5. 2010-09-07. PMID:20502642. |
down syndrome (ds, trisomy 21) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans. |
2010-09-07 |
2023-08-12 |
human |
| William J Netzer, Craig Powell, Yi Nong, Jacqueline Blundell, Lili Wong, Karen Duff, Marc Flajolet, Paul Greengar. Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model. PloS one. vol 5. issue 6. 2010-09-01. PMID:20532168. |
beta-amyloid levels are elevated in down syndrome (ds) patients throughout life and are believed to cause alzheimer's disease (ad) in adult members of this population. |
2010-09-01 |
2023-08-12 |
mouse |
| Kazuko Kudo, Asahito Hama, Seiji Kojima, Ruriko Ishii, Akira Morimoto, Fumio Bessho, Shosuke Sunami, Naoyuki Kobayashi, Akitoshi Kinoshita, Yuri Okimoto, Akio Tawa, Ichiro Tsukimot. Mosaic Down syndrome-associated acute myeloid leukemia does not require high-dose cytarabine treatment for induction and consolidation therapy. International journal of hematology. vol 91. issue 4. 2010-08-13. PMID:20237876. |
the present study aimed to identify optimal treatment intensity in children with mosaic down syndrome (ds) and acute megakaryoblastic leukemia (amkl). |
2010-08-13 |
2023-08-12 |
Not clear |