| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patrick M Cowley, Lori L Ploutz-Snyder, Tracy Baynard, Kevin Heffernan, Sae Young Jae, Sharon Hsu, Miyoung Lee, Kenneth H Pitetti, Michael P Reiman, Bo Fernhal. Physical fitness predicts functional tasks in individuals with Down syndrome. Medicine and science in sports and exercise. vol 42. issue 2. 2010-04-29. PMID:19927019. |
individuals with down syndrome (ds) exhibit reduced strength and aerobic capacity, which may limit their ability to perform functional tasks of daily living. |
2010-04-29 |
2023-08-12 |
Not clear |
| Kate A Alford, Amy Slender, Lesley Vanes, Zhe Li, Elizabeth M C Fisher, Dean Nizetic, Stuart H Orkin, Irene Roberts, Victor L J Tybulewic. Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome. Blood. vol 115. issue 14. 2010-04-27. PMID:20154221. |
trisomy of human chromosome 21 (hsa21) results in down syndrome (ds), a disorder that affects many aspects of physiology, including hematopoiesis. |
2010-04-27 |
2023-08-12 |
mouse |
| P S Hans, R England, S Prowse, E Young, P Z Sheeha. UK and Ireland experience of cochlear implants in children with Down syndrome. International journal of pediatric otorhinolaryngology. vol 74. issue 3. 2010-04-26. PMID:20036016. |
down syndrome (ds) is associated with a high incidence of hearing loss. |
2010-04-26 |
2023-08-12 |
Not clear |
| Mona M Shete, Rose Mary S Stocks, Merry E Sebelik, Robert A Schoumache. Effects of adeno-tonsillectomy on polysomnography patterns in Down syndrome children with obstructive sleep apnea: a comparative study with children without Down syndrome. International journal of pediatric otorhinolaryngology. vol 74. issue 3. 2010-04-26. PMID:20097432. |
to determine if adeno-tonsillectomy (t&a) in children with down syndrome (ds) improves breathing, measured by apnea hypopnea index (ahi), rapid eye movement ahi (rem-ahi) and the lowest oxygen desaturation (sao2), and sleep disruption, measured by arousal index (ari) and time spent in stages 1-4 and rapid eye movement (rem) sleep and compare these results with a group of non-ds children with obstructive sleep apnea (osa). |
2010-04-26 |
2023-08-12 |
Not clear |
| Babu Rao Vundinti, Seema Korgaonkar, Kanjaksha Ghos. Familial small supernumerary marker chromosome (sSMC) (14)(:p11-q11:) [corrected] in a child with translocation Down syndrome. Indian journal of pediatrics. vol 76. issue 12. 2010-04-21. PMID:20012787. |
we report a case of familial small supernumerary marker chromosome (ssmc)in a child with translocation down syndrome (ds)and mother. |
2010-04-21 |
2023-08-12 |
Not clear |
| Beth A Smith, Nick Stergiou, Beverly D Ulric. Lyapunov exponent and surrogation analysis of patterns of variability: profiles in new walkers with and without down syndrome. Motor control. vol 14. issue 1. 2010-04-15. PMID:20237407. |
in previous studies we found that preadolescents with down syndrome (ds) produce higher amounts of variability (smith et al., 2007) and larger lyapunov exponent (lye) values (indicating more instability) during walking than their peers with typical development (td) (buzzi & ulrich, 2004). |
2010-04-15 |
2023-08-12 |
Not clear |
| Adriana S Lima, Bárbara R Cardoso, Silvia F Cozzolin. Nutritional status of zinc in children with Down syndrome. Biological trace element research. vol 133. issue 1. 2010-04-08. PMID:19468695. |
experimental and clinical studies have established that zinc metabolism is altered in individuals with down syndrome (ds). |
2010-04-08 |
2023-08-12 |
Not clear |
| Katheleen J Gardine. Molecular basis of pharmacotherapies for cognition in Down syndrome. Trends in pharmacological sciences. vol 31. issue 2. 2010-04-07. PMID:19963286. |
intellectual disability in down syndrome (ds) ranges from low normal to severely impaired and has a significant impact on the quality-of-life of the individuals affected and their families. |
2010-04-07 |
2023-08-12 |
mouse |
| Christian Arriagada, Miguel Bustamante, Illani Atwater, Eduardo Rojas, Raúl Caviedes, Pablo Caviede. Apoptosis is directly related to intracellular amyloid accumulation in a cell line derived from the cerebral cortex of a trisomy 16 mouse, an animal model of Down syndrome. Neuroscience letters. vol 470. issue 1. 2010-04-06. PMID:20043975. |
human down syndrome (ds) represents the most frequent cause of mental retardation associated to a genetic condition. |
2010-04-06 |
2023-08-12 |
mouse |
| Thomas Eggermann, Nadine Schönherr, Sabrina Spengler, Susanne Jäger, Bernd Denecke, Gerhard Binder, Michael Baudi. Identification of a 21q22 duplication in a Silver-Russell syndrome patient further narrows down the Down syndrome critical region. American journal of medical genetics. Part A. vol 152A. issue 2. 2010-04-02. PMID:20101688. |
several duplications of chromosome 21q helped to narrow down the down syndrome (ds) critical region (dscr) to chromosomal band 21q22 with an approximate length of 5.4 mb. |
2010-04-02 |
2023-08-12 |
Not clear |
| Michael Christiansen, Kasper Pihl, Paula L Hedley, Anne-Cathrine Gjerris, Pia Ø Lind, Severin Olesen Larsen, Lone Krebs, Torben Larse. ADAM 12 may be used to reduce the false positive rate of first trimester combined screening for Down syndrome. Prenatal diagnosis. vol 30. issue 2. 2010-04-01. PMID:20013872. |
adam12 has been shown to be an efficient maternal serum marker for down syndrome (ds) in the first trimester; but recent studies, using a second generation assay, have not confirmed these findings. |
2010-04-01 |
2023-08-12 |
Not clear |
| Haris Kokotas, Maria Grigoriadou, Margareta Mikkelsen, Aglaia Giannoulia-Karantana, Michael B Peterse. Investigating the impact of the Down syndrome related common MTHFR 677C>T polymorphism in the Danish population. Disease markers. vol 27. issue 6. 2010-03-31. PMID:20075510. |
to investigate the relationship between folate metabolism and down syndrome (ds) in a danish population, we analyzed the common 677c>t genetic polymorphism in the methylenetetrahydrofolate reductase (mthfr) gene. |
2010-03-31 |
2023-08-12 |
Not clear |
| Carlos Campos, Rodrigo Guzmán, Encarnación López-Fernández, Angela Casad. Urinary uric acid and antioxidant capacity in children and adults with Down syndrome. Clinical biochemistry. vol 43. issue 3. 2010-03-30. PMID:19786004. |
to evaluate the urinary levels of uric acid (ua) and total antioxidant capacity (tac) with and without ua relative contribution (tac(-ua)) in children and adults with down syndrome (ds) and to prove the clinical use of tac. |
2010-03-30 |
2023-08-12 |
Not clear |
| Julia Looper, Dale A Ulric. Effect of treadmill training and supramalleolar orthosis use on motor skill development in infants with Down syndrome: a randomized clinical trial. Physical therapy. vol 90. issue 3. 2010-03-23. PMID:20075148. |
children with down syndrome (ds) often display delayed onset of independent walking. |
2010-03-23 |
2023-08-12 |
Not clear |
| G V Mendonca, F D Pereira, P P Morato, B Fernhal. Walking economy of adults with Down syndrome. International journal of sports medicine. vol 31. issue 1. 2010-03-17. PMID:20029734. |
this study intended to investigate walking economy (we) in response to different treadmill speeds and grades in adults with down syndrome (ds) and in non-disabled controls. |
2010-03-17 |
2023-08-12 |
human |
| Judith Harriet Tiga. A comparison of acute lymphoblastic leukemia in Down syndrome and non-Down syndrome children: the role of trisomy 21. Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses. vol 26. issue 6. 2010-03-16. PMID:20032297. |
down syndrome (ds), which occurs once in every 800 births, is associated with a trisomy on locus 21. |
2010-03-16 |
2023-08-12 |
Not clear |
| Michael Christianse. Placental growth hormone and growth hormone binding protein are first trimester maternal serum markers of Down syndrome. Prenatal diagnosis. vol 29. issue 13. 2010-03-10. PMID:19844941. |
the potential of pgh and ghbp as maternal serum screening markers for down syndrome (ds) was examined. |
2010-03-10 |
2023-08-12 |
Not clear |
| Maj A Hultén, Suketu Patel, Jon Jonasson, Erik Iwarsso. On the origin of the maternal age effect in trisomy 21 Down syndrome: the Oocyte Mosaicism Selection model. Reproduction (Cambridge, England). vol 139. issue 1. 2010-03-09. PMID:19755486. |
on the basis of this observation we propose that the maternal age effect in down syndrome (ds) is caused by the differential behaviour of trisomy 21 in relation to disomy 21 oocytes during development from foetal life until ovulation in adulthood. |
2010-03-09 |
2023-08-12 |
human |
| Zhenwei Xie, Shiming Lu, Hui L. Contingent triple-screening for Down syndrome in the second trimester: a feasibility study in Mainland Chinese population. Prenatal diagnosis. vol 30. issue 1. 2010-03-09. PMID:19967750. |
to explore the efficacy of contingent triple-screening for down syndrome (ds), that is, performing triple-screening in pregnant women with ds risks between 1/270 and 1/1000 at routine double-screening, in a mainland chinese population. |
2010-03-09 |
2023-08-12 |
Not clear |
| Libi Hertzberg, Elena Vendramini, Ithamar Ganmore, Gianni Cazzaniga, Maike Schmitz, Jane Chalker, Ruth Shiloh, Ilaria Iacobucci, Chen Shochat, Sharon Zeligson, Gunnar Cario, Martin Stanulla, Sabine Strehl, Lisa J Russell, Christine J Harrison, Beat Bornhauser, Akinori Yoda, Gideon Rechavi, Dani Bercovich, Arndt Borkhardt, Helena Kempski, Geertruy te Kronnie, Jean-Pierre Bourquin, Eytan Domany, Shai Izrael. Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. Blood. vol 115. issue 5. 2010-03-05. PMID:19965641. |
we report gene expression and other analyses to elucidate the molecular characteristics of acute lymphoblastic leukemia (all) in children with down syndrome (ds). |
2010-03-05 |
2023-08-12 |
Not clear |