| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Angela E John, Carolyn B Mervi. Comprehension of the communicative intent behind pointing and gazing gestures by young children with Williams syndrome or Down syndrome. Journal of speech, language, and hearing research : JSLHR. vol 53. issue 4. 2010-11-15. PMID:20605941. |
in this study, the authors examined the ability of preschoolers with williams syndrome (ws) or down syndrome (ds) to infer communicative intent as expressed through gestures (pointing and eye-gaze shift). |
2010-11-15 |
2023-08-12 |
Not clear |
| Cristina Fillat, Mara Dierssen, María Martínez de Lagrán, Xavier Altafa. Insights from mouse models to understand neurodegeneration in Down syndrome. CNS & neurological disorders drug targets. vol 9. issue 4. 2010-11-09. PMID:20522013. |
individuals with trisomy 21, also known as down syndrome (ds), develop a clinical syndrome including almost identical neuropathological characteristics of alzheimer's disease (ad) observed in non-ds individuals. |
2010-11-09 |
2023-08-12 |
mouse |
| Aaron B Caughey, Anjali J Kaimal, Anthony O Odib. Cost-effectiveness of Down syndrome screening paradigms. Clinics in laboratory medicine. vol 30. issue 3. 2010-11-08. PMID:20638577. |
several studies have examined the cost-effectiveness of screening for down syndrome (ds). |
2010-11-08 |
2023-08-12 |
Not clear |
| Tsz Kin Lo, Fung King Lai, Wing Cheong Leung, Wai Lam Lau, Lawrence Chang Hung Tang, Robert Kien Howe Chi. A new policy for prenatal screening and diagnosis of Down syndrome for pregnant women with advanced maternal age in a public hospital. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. vol 23. issue 8. 2010-11-04. PMID:19883260. |
before april 2006, women with singleton pregnancy and advanced maternal age (ama, 35 years and older) were offered either direct invasive tests or a variety of screening tests for down syndrome (ds) with routine anomaly scan at 18-20 weeks. |
2010-11-04 |
2023-08-12 |
Not clear |
| Joongkyu Park, Yohan Oh, Lang Yoo, Min-Su Jung, Woo-Joo Song, Sang-Hun Lee, Hyemyung Seo, Kwang Chul Chun. Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells. The Journal of biological chemistry. vol 285. issue 41. 2010-11-04. PMID:20696760. |
down syndrome (ds) is associated with many neural defects, including reduced brain size and impaired neuronal proliferation, highly contributing to the mental retardation. |
2010-11-04 |
2023-08-12 |
mouse |
| Joongkyu Park, Yohan Oh, Lang Yoo, Min-Su Jung, Woo-Joo Song, Sang-Hun Lee, Hyemyung Seo, Kwang Chul Chun. Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells. The Journal of biological chemistry. vol 285. issue 41. 2010-11-04. PMID:20696760. |
those typical characteristics of ds are closely associated with a specific gene group "down syndrome critical region" (dscr) on human chromosome 21. |
2010-11-04 |
2023-08-12 |
mouse |
| Monica Sood, Burton Rochelson, David Krantz, Rachel Ravens, Hima Tam Tam, Nidhi Vohra, Dawnette Lewis, Bidisha Ra. Are second-trimester minor sonographic markers for Down syndrome useful in patients who have undergone first-trimester combined screening? American journal of obstetrics and gynecology. vol 203. issue 4. 2010-11-01. PMID:20633867. |
we sought to determine efficacy of minor markers for detection of down syndrome (ds) in a population prescreened with first-trimester combined screening (fts). |
2010-11-01 |
2023-08-12 |
Not clear |
| Nathan P Cramer, Tyler K Best, Marcus Stoffel, Richard J Siarey, Zygmunt Galdzick. GABAB-GIRK2-mediated signaling in Down syndrome. Advances in pharmacology (San Diego, Calif.). vol 58. 2010-11-01. PMID:20655490. |
down syndrome (ds) results from the presence of an extra copy of genes on the long-arm of chromosome 21. |
2010-11-01 |
2023-08-12 |
Not clear |
| Chelsee A Hewitt, King-Hwa Ling, Tobias D Merson, Ken M Simpson, Matthew E Ritchie, Sarah L King, Melanie A Pritchard, Gordon K Smyth, Tim Thomas, Hamish S Scott, Anne K Vos. Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome. PloS one. vol 5. issue 7. 2010-10-28. PMID:20661276. |
down syndrome (ds) individuals suffer mental retardation with further cognitive decline and early onset alzheimer's disease. |
2010-10-28 |
2023-08-12 |
mouse |
| L Hippolyte, K Iglesias, M Van der Linden, K Barisniko. Social reasoning skills in adults with Down syndrome: the role of language, executive functions and socio-emotional behaviour. Journal of intellectual disability research : JIDR. vol 54. issue 8. 2010-10-20. PMID:20590998. |
although the prevalence of mental illness and behaviour problems is lower in adults with down syndrome (ds) than in other populations with intellectual disabilities, they do present emotional and relational problems, as well as social integration difficulties. |
2010-10-20 |
2023-08-12 |
Not clear |
| Cara J Westmark, Pamela R Westmark, James S Malte. Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures. Journal of Alzheimer's disease : JAD. vol 20. issue 4. 2010-10-12. PMID:20413855. |
amyloid-beta protein precursor (abetapp) is overexpressed in alzheimer's disease (ad), down syndrome (ds), autism, and fragile x syndrome. |
2010-10-12 |
2023-08-12 |
mouse |
| Jisook Park, Dong-Hyun Cha, Jin Woo Jung, Young Hwan Kim, Sook Hwan Lee, Youngjun Kim, Kwang Pyo Ki. Comparative proteomic analysis of human amniotic fluid supernatants with Down syndrome using mass spectrometry. Journal of microbiology and biotechnology. vol 20. issue 6. 2010-10-12. PMID:20622492. |
down syndrome (ds) is an abnormality of the 21st chromosome that commonly occurs in children born to advanced age women. |
2010-10-12 |
2023-08-12 |
human |
| Nagwa A Meguid, Ahmed A Dardir, Eman M El-Sayed, Hanaa H Ahmed, Adel F Hashish, Afaf Ezza. Homocysteine and oxidative stress in Egyptian children with Down syndrome. Clinical biochemistry. vol 43. issue 12. 2010-10-08. PMID:20450901. |
to assess homocysteine, folic acid and vitamin b12, trace element levels and oxidant/antioxidant status in down syndrome (ds) mothers and children. |
2010-10-08 |
2023-08-12 |
Not clear |
| Chan-Kyung J Cho, Christopher R Smith, Eleftherios P Diamandi. Amniotic fluid proteome analysis from Down syndrome pregnancies for biomarker discovery. Journal of proteome research. vol 9. issue 7. 2010-10-07. PMID:20459121. |
down syndrome (ds) is an anomaly caused by an extra chromosome 21, and it affects 1 in 750 live births. |
2010-10-07 |
2023-08-12 |
human |
| Veronica Cimolin, Manuela Galli, Graziano Grugni, Luca Vismara, Giorgio Albertini, Chiara Rigoldi, Paolo Capodagli. Gait patterns in Prader-Willi and Down syndrome patients. Journal of neuroengineering and rehabilitation. vol 7. 2010-10-07. PMID:20565926. |
prader-willi (pws) and down syndrome (ds) are two genetic disorders characterised by some common clinical and functional features. |
2010-10-07 |
2023-08-12 |
Not clear |
| Federico V Pallardó, Ana Lloret, Michel Lebel, Marco d'Ischia, Victoria C Cogger, David G Le Couteur, Maria Nicola Gadaleta, Giuseppe Castello, Giovanni Pagan. Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down Syndrome, Fanconi Anaemia and Werner Syndrome. Biogerontology. vol 11. issue 4. 2010-10-05. PMID:20237955. |
here we review the published evidence for the involvement of oxidative stress in the phenotypes of ataxia-telangiectasia (a-t), down syndrome (ds), fanconi anaemia (fa), and werner syndrome (ws), from the viewpoint of mitochondrial dysfunction. |
2010-10-05 |
2023-08-12 |
human |
| Guido Cocchi, Silvia Gualdi, Caroline Bower, Jane Halliday, Björn Jonsson, Asa Myrelid, Pierpaolo Mastroiacovo, Emmanuelle Amar, Marian K Bakker, Andrea Correa, Berenice Doray, Kari Klungsør Melve, Babak Koshnood, Daniella Landau, Osvaldo M Mutchinick, Anna Pierini, Anukka Ritvanen, Vera Ruddock, Giocchino Scarano, Barbara Sibbald, Antonin Sípek, Romano Tenconi, Dave Tucker, Göran Anneré. International trends of Down syndrome 1993-2004: Births in relation to maternal age and terminations of pregnancies. Birth defects research. Part A, Clinical and molecular teratology. vol 88. issue 6. 2010-10-05. PMID:20589916. |
the aim of this study was to examine trends of down syndrome (ds) in relation to maternal age and termination of pregnancies (top) in 20 registries of the international clearinghouse for birth defects surveillance and research (icbdsr). |
2010-10-05 |
2023-08-12 |
Not clear |
| b' Jadranka Vranekovi\\xc4\\x87, Ivana Babi\\xc4\\x87 Bozovi\\xc4\\x87, Nada Starcevi\\xc4\\x87 Cizmarevi\\xc4\\x87, Alena Bureti\\xc4\\x87-Tomljanovi\\xc4\\x87, Smiljana Risti\\xc4\\x87, Oleg Petrovi\\xc4\\x87, Miljenko Kapovi\\xc4\\x87, Bojana Brajenovi\\xc4\\x87-Mili\\xc4\\x8. Functional inference of methylenetetrahydrofolate reductase gene polymorphisms on enzyme stability as a potential risk factor for Down syndrome in Croatia. Disease markers. vol 28. issue 5. 2010-10-05. PMID:20592453.' |
understanding the biochemical structure and function of the methylenetetrahydrofolate reductase gene (mthfr) provides new evidence in elucidating the risk of having a child with down syndrome (ds) in association with two common mthfr polymorphisms, c677t and a1298c. |
2010-10-05 |
2023-08-12 |
Not clear |
| G Albertini, S Bonassi, V Dall'Armi, I Giachetti, S Giaquinto, M Mignan. Spectral analysis of the voice in Down Syndrome. Research in developmental disabilities. vol 31. issue 5. 2010-09-30. PMID:20488659. |
the voice quality of individuals with down syndrome (ds) is generally described as husky, monotonous and raucous. |
2010-09-30 |
2023-08-12 |
human |
| Joshua D Blazek, Cherie N Billingsley, Abby Newbauer, Randall J Rope. Embryonic and not maternal trisomy causes developmental attenuation in the Ts65Dn mouse model for Down syndrome. Developmental dynamics : an official publication of the American Association of Anatomists. vol 239. issue 6. 2010-09-30. PMID:20503361. |
trisomy 21 results in down syndrome (ds) and causes phenotypes that may result from alterations of developmental processes. |
2010-09-30 |
2023-08-12 |
mouse |