| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nagwa A Meguid, Neveen Hassan Nashaat, Hanaa Reyad Abdallah, Maha Hemimi, Ahmed Elnahry, Hazem Mohamed El-Hariri, Amal Elsaei. Influence of COVID-19 pandemic lockdown on a sample of Egyptian children with Down syndrome. The Egyptian journal of medical human genetics. vol 23. issue 1. 2023-07-31. PMID:37521827. |
down syndrome (ds) is characterized by variable degrees of intellectual disability (id). |
2023-07-31 |
2023-08-14 |
human |
| Patricia A Nadeau, Benoît Jobin, Benjamin Bolle. Diagnostic Sensitivity and Specificity of Cognitive Tests for Mild Cognitive Impairment and Alzheimer's Disease in Patients with Down Syndrome: A Systematic Review and Meta-Analysis. Journal of Alzheimer's disease : JAD. 2023-07-31. PMID:37522203. |
improved health care for people with down syndrome (ds) has resulted in an increase in their life expectancy therefore increasing comorbidities associated with age-related problems in this population, the most frequent being alzheimer's disease (ad). |
2023-07-31 |
2023-08-14 |
Not clear |
| Richard E Griffioen, Geert J M van Boxtel, Theo Verheggen, Marie-Jose Enders-Slegers, Steffie Van Der Stee. Group Changes in Cortisol and Heart Rate Variability of Children with Down Syndrome and Children with Autism Spectrum Disorder during Dog-Assisted Therapy. Children (Basel, Switzerland). vol 10. issue 7. 2023-07-29. PMID:37508697. |
dog-assisted therapy is hypothesized to lower stress in children with autism spectrum disorder (asd) and children with down syndrome (ds), which may be visible on a physiological level. |
2023-07-29 |
2023-08-14 |
Not clear |
| Yuqiu Zhou, Li Tao, Ying Zh. TempShift Reveals the Sequential Development of Human Neocortex and Skewed Developmental Timing of Down Syndrome Brains. Brain sciences. vol 13. issue 7. 2023-07-29. PMID:37509002. |
currently, the regulation of developmental timing across neocortical areas and developmental changes in down syndrome (ds) brains remain unclear. |
2023-07-29 |
2023-08-14 |
human |
| Shojiro Ichimata, Ivan Martinez-Valbuena, Seojin Lee, Jun Li, Ali M Karakani, Gabor G Kovac. Distinct Molecular Signatures of Amyloid-Beta and Tau in Alzheimer's Disease Associated with Down Syndrome. International journal of molecular sciences. vol 24. issue 14. 2023-07-29. PMID:37511361. |
limited comparative data exist on the molecular spectrum of amyloid-beta (aβ) and tau deposition in individuals with down syndrome (ds) and sporadic alzheimer's disease (sad). |
2023-07-29 |
2023-08-14 |
Not clear |
| Mohammad Khursheed Alam, Ahmed Hamoud L Alsharari, Maher A L Shayeb, Sittana Elfadil, Gabriele Cervino, Giuseppe Minervin. Prevalence of Bruxism in Down Syndrome Patients: A Systematic Review and Metanalysis. Journal of oral rehabilitation. 2023-07-28. PMID:37507203. |
bruxism is a parafunctional activity characterized by grinding or clenching of teeth and is a common oral health concern in individuals with down syndrome (ds). |
2023-07-28 |
2023-08-14 |
Not clear |
| Osama Hamadelseed, Thomas Skutell. Correlating MRI-based brain volumetry and cognitive assessment in people with Down syndrome. Brain and behavior. 2023-07-27. PMID:37496380. |
down syndrome (ds) is the most common genetic cause of intellectual disability. |
2023-07-27 |
2023-08-14 |
Not clear |
| Xu-Qiao Chen, Mariko Sawa, Ann Becker, Dmitry Karachentsev, Xinxin Zuo, Kevin D Rynearson, Rudolph E Tanzi, William C Moble. Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ-Secretase Modulator. Annals of neurology. vol 94. issue 2. 2023-07-27. PMID:37042072. |
down syndrome (ds) shares neuropathological features with ad. |
2023-07-27 |
2023-11-08 |
Not clear |
| Eunju Im, Ying Jiang, Philip H Stavrides, Sandipkumar Darji, Hediye Erdjument-Bromage, Thomas A Neubert, Jun Yong Choi, Jerzy Wegiel, Ju-Hyun Lee, Ralph A Nixo. Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr Science advances. vol 9. issue 30. 2023-07-26. PMID:37494443. |
herein, we show that amyloid precursor protein (app), linked to early-onset ad in down syndrome (ds), acts directly via its β-c-terminal fragment (βctf) to disrupt lysosomal vacuolar (h |
2023-07-26 |
2023-08-14 |
mouse |
| Bianca Rusu, Bharti Kukreja, Taiyi Wu, Sophie J Dan, Min Yi Feng, Brian T Kalis. Single-nucleus profiling identifies accelerated oligodendrocyte precursor cell senescence in a mouse model of Down Syndrome. eNeuro. 2023-07-25. PMID:37491366. |
down syndrome (ds), the most common genetic cause of intellectual disability, is associated with lifelong cognitive deficits. |
2023-07-25 |
2023-08-14 |
mouse |
| Sigan L Hartley, Victoria Fleming, Emily K Schworer, Jamie Peven, Benjamin L Handen, Sharon Krinsky-McHale, Christy Hom, Laisze Lee, Dana L Tudorascu, Charles Laymon, Davneet Minhas, Weiquan Luo, Annie Cohen, Shahid Zaman, Beau M Ances, Mark Mapstone, Elizabeth Head, Florence Lai, H Diana Rosas, William Klunk, Bradley Christia. Timing of Alzheimer's Disease by Intellectual Disability Level in Down Syndrome. Journal of Alzheimer's disease : JAD. 2023-07-24. PMID:37482997. |
trisomy 21 causes down syndrome (ds) and is a recognized cause of early-onset alzheimer's disease (ad). |
2023-07-24 |
2023-08-14 |
Not clear |
| Elyse C Page, Susan L Heatley, Jacqueline Rehn, Paul Q Thomas, David T Yeung, Deborah L Whit. Gain of chromosome 21 increases the propensity for Frontiers in oncology. vol 13. 2023-07-24. PMID:37483494. |
gain of chromosome 21 increases the propensity for acute lymphoblastic leukemia (all) patients with a gain of chromosome 21, intrachromosomal amplification of chromosome 21 (iamp21), or down syndrome (ds), have increased expression of genes in the ds critical region (dscr) of chromosome 21, including the high-mobility group nucleosome-binding protein 1, |
2023-07-24 |
2023-08-14 |
Not clear |
| Gustavo Wandresen, Fernanda Sgarbi, Lais Tomiura, Nancy Palmieri de Oliveira, Renato Nisihar. Concerns Regarding Gynecological Aspects of Brazilian Girls and Women With Down Syndrome: A Cross-Sectional Study of Caregivers' Opinions. Annals of family medicine. vol 21. issue 4. 2023-07-24. PMID:37487717. |
girls and women with down syndrome (ds) and their caregivers may have more difficulties in dealing with puberty, menstruation, and sexuality than those without ds. |
2023-07-24 |
2023-08-14 |
Not clear |
| Eric Rubenstein, Nichole Kyprianou, Prisha Sujin Kumar, Anna-Mariya Kriova, Alexis Sokoloff, Hampus Hillerstrom, James Hendri. Healthcare and Behavior Changes for Adults With Down Syndrome 1-Year Into COVID-19. American journal on intellectual and developmental disabilities. vol 128. issue 4. 2023-07-20. PMID:37470258. |
individuals with down syndrome (ds) have been disproportionately harmed by the covid-19 pandemic and may have been more likely to have sacrificed opportunity and activity to avoid potential exposures. |
2023-07-20 |
2023-08-14 |
Not clear |
| Yao Chen, Yanyu Xiao, Yanye Zhang, Renying Wang, Feixia Wang, Huajing Gao, Yifeng Liu, Runju Zhang, Huiyu Sun, Ziming Zhou, Siwen Wang, Kai Chen, Yixi Sun, Mixue Tu, Jingyi Li, Qiong Luo, Yiqing Wu, Linling Zhu, Yun Huang, Xiao Sun, Guoji Guo, Dan Zhan. Single-cell landscape analysis reveals systematic senescence in mammalian Down syndrome. Clinical and translational medicine. vol 13. issue 7. 2023-07-18. PMID:37461266. |
down syndrome (ds), which is characterized by various malfunctions, is the most common chromosomal disorder. |
2023-07-18 |
2023-08-14 |
Not clear |
| Kira Cozzolino, Lynn Sanford, Samuel Hunter, Kayla Molison, Benjamin Erickson, Taylor Jones, Deepa Ajit, Matthew D Galbraith, Joaquin M Espinosa, David L Bentley, Mary A Allen, Robin D Dowell, Dylan J Taatje. Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome. bioRxiv : the preprint server for biology. 2023-07-18. PMID:37461585. |
hyperactive interferon (ifn) signaling is a hallmark of down syndrome (ds), a condition caused by trisomy 21 (t21); strategies that normalize ifn signaling could benefit this population. |
2023-07-18 |
2023-08-14 |
Not clear |
| Shintaro Takenoshita, Seishi Terada, Tomokazu Inoue, Taku Kurozumi, Norihito Yamada, Ryozo Kuwano, Shigeru Suemits. Prevalence and modifiable risk factors for dementia in persons with intellectual disabilities. Alzheimer's research & therapy. vol 15. issue 1. 2023-07-18. PMID:37464412. |
people with intellectual disability (id) without down syndrome (ds) are presumed to be at higher risk of developing dementia due to their lower baseline cognitive reserve. |
2023-07-18 |
2023-08-14 |
Not clear |
| Madison S Dulin, Susan J Loveall, Laura J Matti. Home-literacy environments and language development in toddlers with Down syndrome. Frontiers in psychology. vol 14. 2023-07-17. PMID:37457096. |
the present study aimed to (1) characterize the home-literacy environments (hle) of toddlers with down syndrome (ds) and (2) examine if richness of the hle, child engagement during shared storybook reading activities, quality of a caregiver-child shared storybook reading activity, and exposure to language in the home environment predicted child receptive vocabulary concurrently (time 1) and 6 months later (time 2). |
2023-07-17 |
2023-08-14 |
Not clear |
| Sarah Tanner, Andrew Collaro, Jasneek Chawl. The management of residual OSA post-adenotonsillectomy in children with down syndrome: The experience of a large tertiary sleep service. Sleep medicine. vol 109. 2023-07-16. PMID:37454605. |
obstructive sleep apnoea (osa) is common in children with down syndrome (ds). |
2023-07-16 |
2023-08-14 |
Not clear |
| Arielle Hershkovich, Daria Lasc, Lauren Grove, Daniel Sullivan, Yingying Yan. Visuospatial perspective taking in people with Down syndrome. Research in developmental disabilities. vol 139. 2023-07-15. PMID:37453151. |
despite research advances in spatial cognition, little is known about vpt in people with down syndrome (ds). |
2023-07-15 |
2023-08-14 |
dog |