| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew D Zammit, Tobey J Betthauser, Andrew K McVea, Charles M Laymon, Dana L Tudorascu, Sterling C Johnson, Sigan L Hartley, Alexander K Converse, Davneet S Minhas, Shahid H Zaman, Beau M Ances, Charles K Stone, Chester A Mathis, Annie D Cohen, William E Klunk, Benjamin L Handen, Bradley T Christia. Characterizing the emergence of amyloid and tau burden in Down syndrome. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-08-29. PMID:37641577. |
almost all individuals with down syndrome (ds) will develop neuropathological features of alzheimer's disease (ad). |
2023-08-29 |
2023-09-07 |
Not clear |
| Olfat Aboleil-Zoubi, Chen Gafni-Amsalem, Lilach Peled-Perets, Efrat Mamluk, Liron Tamir, Shadia Hakrosh, Shoshana Kurtzman, Elena Chervinsky, Ula Aalimi, Bashir Husam, Morad Khayat, Ayelet Baram-Tsabari, Stavit A Shale. The effect of a prior e-learning tool on genetic counseling outcomes in diverse ethnic couples with abnormal Down syndrome screening tests: A randomized controlled trial. Journal of genetic counseling. 2023-08-26. PMID:37632224. |
genetic counseling (gc) following abnormal down syndrome (ds) screening tests aims to ensure learning of complex medical concepts and discussion of counselees' personal desires. |
2023-08-26 |
2023-09-07 |
human |
| Maria Vitoria Gomes da Silva, Laura Resende Guimarães Pereira, Lucimar Retto da Silva de Avó, Carla Maria Ramos Germano, Débora Gusmão Mel. Enhancing understanding of SARS-CoV-2 infection among individuals with Down syndrome: An integrative review. Sao Paulo medical journal = Revista paulista de medicina. vol 142. issue 2. 2023-08-23. PMID:37610949. |
down syndrome (ds) is a non-rare genetic condition that affects approximately 1 in every 800 live births worldwide. |
2023-08-23 |
2023-09-07 |
Not clear |
| Osama Hamadelseed, Mike K S Chan, Michelle B F Wong, Thomas Skutell. Distinct neuroanatomical and neuropsychological features of Down syndrome compared to related neurodevelopmental disorders: a systematic review. Frontiers in neuroscience. vol 17. 2023-08-21. PMID:37600012. |
we critically review research findings on the unique changes in brain structure and cognitive function characteristic of down syndrome (ds) and summarize the similarities and differences with other neurodevelopmental disorders such as williams syndrome, 22q11.2 deletion syndrome, and fragile x syndrome. |
2023-08-21 |
2023-09-07 |
Not clear |
| Amr M Zaki, Sirichai Pasadhika, Jerry C Huang, Akshay S Thomas, Bryn M Burkholder, Lyndell L Lim, Stephanie M Llop, Eric B Suhler, Grazyna Adamus, James T Rosenbau. Characterization of autoimmune eye disease in association with Down's syndrome. Eye (London, England). 2023-08-19. PMID:37598261. |
autoimmunity and deficiency of the transcription factor autoimmune regulator protein (aire) are known associations with down syndrome (ds). |
2023-08-19 |
2023-09-07 |
human |
| Tiffany J Glass, Charles Lenell, Erin H Fisher, Qiuyu Yang, Nadine P Conno. Ultrasonic Vocalization Phenotypes in the Ts65Dn and Dp(16)1Yey Mouse Models of Down syndrome. Physiology & behavior. 2023-08-13. PMID:37573959. |
down syndrome (ds) is a developmental disorder associated with a high incidence of challenges in vocal communication. |
2023-08-13 |
2023-08-16 |
mouse |
| Saroja Devi Geetha, Ram Singh, Meira Shaham, Ninette Cohen, Kristin Sticc. Transient abnormal myelopoiesis with extramedullary involvement in a down syndrome preemie leading to an unresponsive course despite chemotherapy. Leukemia research reports. vol 20. 2023-08-10. PMID:37560406. |
transient abnormal myelopoiesis (tam) is a transient, clonal myeloproliferative disorder unique to down syndrome (ds) babies. |
2023-08-10 |
2023-08-16 |
Not clear |
| Yara Abukhaled, Kenana Hatab, Mohammad Awadhalla, Hamdan Hamda. Understanding the genetic mechanisms and cognitive impairments in Down syndrome: towards a holistic approach. Journal of neurology. 2023-08-10. PMID:37561187. |
the most common genetic cause of intellectual disability is down syndrome (ds), trisomy 21. |
2023-08-10 |
2023-08-16 |
human |
| Egambaram Senthilvel, Kahir Jawad, Bakeerathan Gunaratnam, Juhee N Mian, Karim El-Kers. Prevalence, associated risk factors, and respiratory event distribution of obstructive sleep apnea in children with Down syndrome. Sleep & breathing = Schlaf & Atmung. 2023-08-10. PMID:37563524. |
children with down syndrome (ds) have a high prevalence of obstructive sleep apnea (osa). |
2023-08-10 |
2023-08-16 |
Not clear |
| Samantha N Thomas, Brian F Niemeyer, Rocio J Jimenez-Valdes, Alexander J Kaiser, Joaquin M Espinosa, Kelly D Sullivan, Andrew Goodspeed, James C Costello, Jonathan K Alder, Rodrigo Cañas-Arranz, Adolfo García-Sastre, Kambez H Bena. Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection. iScience. vol 26. issue 8. 2023-08-09. PMID:37554445. |
individuals with down syndrome (ds) clinically manifest severe respiratory illnesses; however, there is a paucity of data on how ds influences homeostatic physiology of lung airway, and its reactive responses to pulmonary pathogens. |
2023-08-09 |
2023-08-16 |
mouse |
| Deborah J Fidler, Kaylyn Van Deusen, Mark A Prince, Emily K Schworer, Nancy R Lee, Jamie O Edgin, Lina R Patel, Lisa A Daunhaue. Longitudinal Predictors of Neurodevelopmental Outcomes in Children with Down Syndrome. Developmental neuropsychology. 2023-08-09. PMID:37555433. |
this study examined longitudinal predictors of neurodevelopmental outcomes in children with down syndrome (ds). |
2023-08-09 |
2023-08-16 |
human |
| Daniel Combs, Jamie Edgin, Chiu-Hsieh Hsu, Kenneth Bottrill, Hailey Van Vorce, Blake Gerken, Daniel Matloff, Sicily La Rue, Sairam Parthasarath. The combination of atomoxetine and oxybutynin for the treatment of obstructive sleep apnea in children with Down syndrome. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2023-08-09. PMID:37555595. |
children with down syndrome (ds) are at very high risk for obstructive sleep apnea (osa). |
2023-08-09 |
2023-08-16 |
Not clear |
| Emily Miyoshi, Samuel Morabito, Caden M Henningfield, Negin Rahimzadeh, Sepideh Kiani Shabestari, Sudeshna Das, Neethu Michael, Fairlie Reese, Zechuan Shi, Zhenkun Cao, Vanessa Scarfone, Miguel A Arreola, Jackie Lu, Sierra Wright, Justine Silva, Kelsey Leavy, Ira T Lott, Eric Doran, William H Yong, Saba Shahin, Mari Perez-Rosendahl, Elizabeth Head, Kim N Green, Vivek Swaru. Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease. bioRxiv : the preprint server for biology. 2023-08-07. PMID:37546983. |
here we present a transcriptomic survey of ad using spatial transcriptomics (st) and single-nucleus rna-seq in cortical samples from early-stage ad, late-stage ad, and ad in down syndrome (ad in ds) donors. |
2023-08-07 |
2023-08-14 |
mouse |
| Michele Polfuss, Linda G Bandini, Michele N Ravelli, Zijian Huang, Andrea Moosreiner, Dale A Schoeller, Chiang-Ching Huang, Dan Ding, Cristen Berry, Emma Marston, Azeem Hussain, Timothy C Shriver, Kathleen J Sawi. Energy expenditure and weight-related behaviors in youth with Down syndrome: a protocol. Frontiers in pediatrics. vol 11. 2023-08-07. PMID:37547107. |
the consequences of obesity are ominous, yet healthcare professionals are not adequately preventing or treating obesity in youth with down syndrome (ds). |
2023-08-07 |
2023-08-14 |
Not clear |
| Zuolin Zhou, Chunchun Zhi, Die Chen, Zhaowei Cai, Xiaoling Jian. Single-nucleus RNA sequencing reveals cell type-specific transcriptome alterations of Down syndrome hippocampus using the Dp16 mouse model. Genes & genomics. 2023-08-07. PMID:37548883. |
down syndrome (ds), the most frequently occurring human chromosomal disorder, is caused by trisomy 21. |
2023-08-07 |
2023-08-14 |
mouse |
| April D Adams, Jielu Lin, Diana W Bianchi, Lauren Bishop, Taisuke Sato, Laura L Baxter, Victoria Hoffmann, Laura Koehly, Faycal Gued. Embryonic Statistical Analyses Reveal Two Growth Phenotypes in Mouse Models of Down Syndrome. American journal of obstetrics and gynecology. 2023-08-06. PMID:37544351. |
down syndrome (ds) is associated with several comorbidities, including intellectual disability, growth restriction and congenital heart defects. |
2023-08-06 |
2023-08-14 |
mouse |
| Yosra Bejaoui, Sara Alresheq, Sophie Durand, Marie Vilaire-Meunier, Louise Maillebouis, Ayman Al Haj Zen, André Mégarbané, Nady El Haj. DNA methylation profiling in Trisomy 21 females with and without breast cancer. Frontiers in oncology. vol 13. 2023-08-04. PMID:37538118. |
down syndrome (ds) is the most common chromosome anomaly in humans and occurs due to an extra copy of chromosome 21. |
2023-08-04 |
2023-08-14 |
Not clear |
| Lara de Almeida Rodrigues, Aline de Melo, Náguia de Medeiros, Ana Resende Camargo. Family-professional collaborative intervention via telehealth with an infant with Down syndrome and visual impairment: a case report. Physiotherapy theory and practice. 2023-08-04. PMID:37540216. |
however, no study was found that used a physiotherapy intervention via telehealth for infants with down syndrome (ds). |
2023-08-04 |
2023-08-14 |
Not clear |
| Hurlihal Sharath Chandra, Jency Samuel Johnson, Lakshmi Sagar, Makam Naveen, Shaik Ziauddin, Frankantony Britto, Krishnamoorthy Shankar Havaldar, Hurlihal Shalin. A Comparative Evaluation of Physical Parameters of Saliva and Correlation with Periodontal Condition in Down Syndrome Children and Healthy Controls. The journal of contemporary dental practice. vol 24. issue 6. 2023-08-03. PMID:37534503. |
the aim of this study was to assess the significance and role of physical parameters of saliva on periodontal health in children with down syndrome (ds). |
2023-08-03 |
2023-08-14 |
Not clear |
| Luyao Liu, Yuxin Sun, Ping Xu, Ying Wan. Clinical Value of Serum miR-124 and miR-200C Combined with Ultrasound NT in Screening Down Syndrome in Elderly Puerperae in the Second Trimester. Alternative therapies in health and medicine. 2023-08-03. PMID:37535911. |
to evaluate the clinical value of serum mir-124 and mir-200c combined with ultrasound nt in screening down syndrome (ds) in elderly puerperae during the second trimester. |
2023-08-03 |
2023-08-14 |
Not clear |