| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aurora Blanco-Montaño, Monserrat Ramos-Arenas, Bryssia Adilene Yerena-Echevarría, Laura Daniela Miranda-Santizo, Ana Luisa Ríos-Celis, Ammi Tzahala Dorantes-Gómez, Alondra Jackeline Morato-Rangel, Jessica Alejandra Meza-Hernández, Elisa Daniela Acosta-Saldívar, Carlos Diego Aguilar-Castillo, Alan Cárdenas-Conej. [Risk factors in the origin of Down syndrome]. Revista medica del Instituto Mexicano del Seguro Social. vol 61. issue 5. 2023-09-28. PMID:37769135. |
down syndrome (ds) is the most common autosomal aneuploidy and the leading cause of intellectual disability of genetic origin worldwide. |
2023-09-28 |
2023-10-07 |
Not clear |
| Michele Lacerda de Andrade, Soraia Micaela Silva, Janaina Ferreira de Moraes, Stephanie Cardoso de Jesus, Emily Dos Santos Pedro, João Carlos Ferrari Corrêa, Fernanda Ishida Corrê. Predictors of the social participation of adults with Down syndrome: an analysis based on the biopsychosocial model of the International Classification of Functioning, Disability, and Health. American journal of physical medicine & rehabilitation. 2023-09-27. PMID:37752638. |
identify the predictors of social participation in down syndrome (ds) adults from the biopsychosocial model of the international classification of functioning, disability, and health (icf). |
2023-09-27 |
2023-10-07 |
Not clear |
| Luca Pecoraro, Elena Ferron, Martina Solfa, Massimo Mirandola, Silvana Lauriola, Giorgio Piacentini, Angelo Pietrobell. Body composition and laboratory parameters in children with down syndrome: The DONUT study. Clinical nutrition ESPEN. vol 57. 2023-09-22. PMID:37739665. |
children affected by down syndrome (ds) have a higher prevalence of obesity, dyslipidemia, and altered liver enzymes. |
2023-09-22 |
2023-10-07 |
Not clear |
| Salvatore Vaiasicca, Gianmarco Melone, David W James, Marcos Quintela, Alessandra Preziuso, Richard H Finnell, Robert Steven Conlan, Lewis W Francis, Bruna Corradett. Transcriptomic analysis of stem cells from chorionic villi uncovers the impact of chromosomes 2, 6 and 22 in the clinical manifestations of Down syndrome. Stem cell research & therapy. vol 14. issue 1. 2023-09-22. PMID:37740230. |
down syndrome (ds) clinical multisystem condition is generally considered the result of a genetic imbalance generated by the extra copy of chromosome 21. |
2023-09-22 |
2023-10-07 |
Not clear |
| T Siyah, M Saglam, N V Yagli, I Ertugrul, H H Aykan, T Karago. Investigation of cardiopulmonary parameters, motor development and muscle strength in children with Down syndrome with and without congenital heart disease. Journal of intellectual disability research : JIDR. 2023-09-21. PMID:37731317. |
children with down syndrome (ds) frequently have concomitant clinical problems. |
2023-09-21 |
2023-10-07 |
Not clear |
| Wenjuan Zhu, Wenqiang Liu, Rebecca Yu, Melanie Manning, Anitra Waran Romfh, Joseph C W. Generation of two induced pluripotent stem cell lines from patients with Down syndrome. Stem cell research. vol 72. 2023-09-21. PMID:37734318. |
down syndrome (ds) is caused by trisomy of homo sapiens chromosome 21 (hsa21) and is by far the most common chromosomal disorder accompanied by neurodevelopmental disorders and congenital heart disease. |
2023-09-21 |
2023-10-07 |
Not clear |
| Lauren V Schneider, G Lynn Mitchell, Jason D Marsack, Heather A Anderso. Visual Acuity Prediction Based on Different Refraction Types For Patients With Down Syndrome. Translational vision science & technology. vol 12. issue 9. 2023-09-19. PMID:37725391. |
the purpose of this study was to determine if control observers can be used as surrogates to predict visual acuity (va) of patients with down syndrome (ds). |
2023-09-19 |
2023-10-07 |
Not clear |
| Eman Eissa, Hanan H Afifi, Assem M Abo-Shanab, Manal M Thomas, Mohamed B Taher, Rania Kandil, Naglaa M Kholouss. Importance of TREC and KREC as molecular markers for immunological evaluation of down syndrome children. Scientific reports. vol 13. issue 1. 2023-09-18. PMID:37723211. |
recurrent and severe infections occurred in children with down syndrome (ds) due to immunological parameter defects have been reported. |
2023-09-18 |
2023-10-07 |
Not clear |
| Athanasios Oikonomou, Luigia Valsecchi, Manuel Quadri, Titus Watrin, Katerina Scharov, Simona Procopio, Jia-Wey Tu, Melina Vogt, Angela Maria Savino, Daniela Silvestri, Maria Grazia Valsecchi, Andrea Biondi, Arndt Borkhardt, Sanil Bhatia, Giovanni Cazzaniga, Grazia Fazio, Michela Bardini, Chiara Palm. High-throughput screening as a drug repurposing strategy for poor outcome subgroups of pediatric B-cell precursor Acute Lymphoblastic Leukemia. Biochemical pharmacology. 2023-09-17. PMID:37717691. |
the aim of this study was to apply htp drug screening to identify potentially effective compounds for the treatment of pediatric bcp-all patients with poor prognosis, such as patients with down syndrome (ds) or carrying rearrangements involving pax5 or kmt2a/mll genes. |
2023-09-17 |
2023-10-07 |
human |
| Sarah Pizzano, Gabriella R Sterne, Macy W Veling, L Amanda Xu, Ty Hergenreder, Bing Y. The Drosophila homolog of APP promotes Dscam expression to drive axon terminal growth, revealing interaction between Down syndrome genes. Disease models & mechanisms. vol 16. issue 9. 2023-09-15. PMID:37712356. |
down syndrome (ds) is caused by triplication of human chromosome 21 (hsa21). |
2023-09-15 |
2023-10-07 |
human |
| Sarah Pizzano, Gabriella R Sterne, Macy W Veling, L Amanda Xu, Ty Hergenreder, Bing Y. The Drosophila homolog of APP promotes Dscam expression to drive axon terminal growth, revealing interaction between Down syndrome genes. Disease models & mechanisms. vol 16. issue 9. 2023-09-15. PMID:37712356. |
previous studies have indicated that amyloid precursor protein (app) and down syndrome cell adhesion molecule (dscam) regulate neuronal morphology and contribute to neuronal aberrations in ds. |
2023-09-15 |
2023-10-07 |
human |
| Maomiao Peng, Annalysa Lovos, Kenneth Bottrill, Katharine Hughes, Miranda Sampsel, Nancy Raitano Lee, Leonard Abbeduto, Angela John Thurman, Jamie Edgi. Extended trajectory of spatial memory errors in typical and atypical development: The role of binding and precision. Hippocampus. 2023-09-14. PMID:37706613. |
we examined these errors in children aged 3-18 years, making comparisons between children with typical development (td) and children with down syndrome (ds), a population with known memory challenges. |
2023-09-14 |
2023-10-07 |
Not clear |
| Rie Kitano, Neel Madan, Takahisa Mikami, Rajeevi Madankumar, Brian G Skotko, Stephanie Santoro, Steven J Ralston, Diana W Bianchi, Tomo Taru. Biometric magnetic resonance imaging analysis of fetal brain development in down syndrome. Prenatal diagnosis. 2023-09-12. PMID:37698481. |
to assess brain development in living fetuses with down syndrome (ds) by biometric measurements on fetal brain magnetic resonance images (mri). |
2023-09-12 |
2023-10-07 |
Not clear |
| Abdullah Alnoman, Haitham A Baghlaf, Ahmad M Badeghiesh, Magdalena Peeva, Michael H Daha. Pregnancy, delivery, and neonatal outcomes among women living with Down syndrome: a matched cohort study, utilizing a population database. Archives of gynecology and obstetrics. 2023-09-12. PMID:37698605. |
we utilized a population database to address the paucity of data around pregnancy outcomes in women with down syndrome (ds). |
2023-09-12 |
2023-10-07 |
Not clear |
| Carla Talita Azevedo Ginani, Jefferson Romáryo Duarte da Luz, Kleyton Santos de Medeiros, Ayane Cristine Alves Sarmento, Fabio Coppedè, Maria das Graças Almeid. Association of C677T and A1298C polymorphisms of the MTHFR gene with maternal risk for Down syndrome: a meta-analysis of case-control studies. Mutation research. Reviews in mutation research. 2023-09-09. PMID:37689109. |
several studies around the world support the hypothesis that genetic polymorphisms involved in folate metabolism could be related to the maternal risk for down syndrome (ds). |
2023-09-09 |
2023-10-07 |
Not clear |
| H Sawatari, A Chishaki, A Rahmawati, S And. Growth-related changes in the influence of obesity on signs suggesting sleep-disordered breathing and sleepiness in young individuals with Down syndrome. Journal of intellectual disability research : JIDR. 2023-09-06. PMID:37671733. |
sleep-disordered breathing (sdb) is highly prevalent in individuals with down syndrome (ds), who cease growing earlier than individuals without ds. |
2023-09-06 |
2023-10-07 |
Not clear |
| Keiichi Ishihara, Eri Kawashita, Satoshi Akib. Bio-Metal Dyshomeostasis-Associated Acceleration of Aging and Cognitive Decline in Down Syndrome. Biological & pharmaceutical bulletin. vol 46. issue 9. 2023-09-04. PMID:37661395. |
down syndrome (ds), which is caused by triplication of human chromosome 21 (hsa21), exhibits some physical signs of accelerated aging, such as graying hair, wrinkles and menopause at an unusually young age. |
2023-09-04 |
2023-09-07 |
human |
| Caoimhe McKenna, Anne Schilder, Rachel Xue Ning Lee, Logan Manikam, Roderick Venekamp, Monica Lakhanpau. Mapping Two Decades of Paediatric Down Syndrome Research Literature. The Ulster medical journal. vol 92. issue 2. 2023-08-31. PMID:37649911. |
while research has led to significant advancements in the health and life expectancy of children with down syndrome (ds), there remains a significant burden of disease and health inequity. |
2023-08-31 |
2023-09-07 |
Not clear |
| Başak Erdemli Gürsel, İlker Ercan, İbrahim Şahin, Gökhan Önge. Morphometric Shape Analysis of Corpus Callosum in Children With Down Syndrome. Clinical pediatrics. 2023-08-31. PMID:37650518. |
down syndrome (ds) is characterized by varying degrees of mental retardation and delay in neurocognitive functions. |
2023-08-31 |
2023-09-07 |
Not clear |
| Sigan L Hartley, Benjamin Handen, Dana Tudorascu, Laisze Lee, Annie Cohen, Emily K Schworer, Jamie C Peven, Matthew Zammit, William Klunk, Charles Laymon, Davneet Minhas, Weiquan Luo, Shahid Zaman, Beau Ances, Gregory Preboske, Bradley T Christia. AT(N) biomarker profiles and Alzheimer's disease symptomology in Down syndrome. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-08-29. PMID:37641428. |
down syndrome (ds) is a genetic cause of early-onset alzheimer's disease (ad). |
2023-08-29 |
2023-09-07 |
Not clear |