| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicole T Baumer, Margaret A Hojlo, Katherine G Pawlowski, Anna L Milliken, Angela M Lombardo, Sabrina Sargado, Cara Soccorso, Emily J Davidson, William J Barbares. Co-occurring conditions in Down syndrome: Findings from a clinical database. American journal of medical genetics. Part C, Seminars in medical genetics. 2023-10-24. PMID:37873945. |
individuals with down syndrome (ds) experience a range of medical and neurodevelopmental conditions, necessitating systematic study of their occurrence and impact on neurodevelopmental outcomes. |
2023-10-24 |
2023-11-08 |
Not clear |
| Nicole T Baumer, Margaret A Hojlo, Katherine G Pawlowski, Anna L Milliken, Angela M Lombardo, Sabrina Sargado, Cara Soccorso, Emily J Davidson, William J Barbares. Co-occurring conditions in Down syndrome: Findings from a clinical database. American journal of medical genetics. Part C, Seminars in medical genetics. 2023-10-24. PMID:37873945. |
we created a prospective clinical database of individuals with ds, integrated into the workflow of a specialty down syndrome program at a specialty pediatric referral hospital. |
2023-10-24 |
2023-11-08 |
Not clear |
| Kelly J Gardner, Wei Wang, Elizabeth B Klerma. Altered sleep architecture in children and adolescents with Down syndrome. American journal of medical genetics. Part C, Seminars in medical genetics. 2023-10-23. PMID:37870492. |
children with down syndrome (ds) may experience changes in sleep architecture (i.e., different sleep stages) that then affect waketime functioning, including learning, mood, and disruptive behavior. |
2023-10-23 |
2023-11-08 |
Not clear |
| Nicole T Baumer, George Capon. Psychopharmacological treatments in Down syndrome and autism spectrum disorder: State of the research and practical considerations. American journal of medical genetics. Part C, Seminars in medical genetics. 2023-10-23. PMID:37870763. |
individuals with down syndrome (ds) or autism spectrum disorder (asd), and especially those with both ds and co-occurring asd (ds + asd) commonly display behavioral and psychiatric symptoms that can impact quality of life and places increased burden on caregivers. |
2023-10-23 |
2023-11-08 |
Not clear |
| Stephanie L Santoro, Carolyn H Baloh, Sarah J Hart, Nora Horick, Priya S Kishnani, Kavita Krell, Nicolas M Oreskovic, Mikayla Shaffer, Nasreen Talib, Amy Torres, Gail A Spiridigliozzi, Brian G Skotk. Pneumonia vaccine response in individuals with Down syndrome at three specialty clinics. American journal of medical genetics. Part C, Seminars in medical genetics. 2023-10-21. PMID:37864360. |
individuals with down syndrome (ds) have been particularly impacted by respiratory conditions, such as pneumonia. |
2023-10-21 |
2023-11-08 |
Not clear |
| Carolyn A Chabuz, Taylor G Lackey, Kaci L Pickett, Norman R Friedma. Accuracy of parental perception of nighttime breathing in children with Down syndrome after adenotonsillectomy. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 2023-10-20. PMID:37858282. |
clinical practice guidelines recommend screening all children with down syndrome (ds) for obstructive sleep apnea (osa) with polysomnography (psg) by age 4 years. |
2023-10-20 |
2023-11-08 |
Not clear |
| Atefeh Karimi, Eliza L Nelso. Motor-language links in children with Down syndrome: a scoping review to revisit the literature with a developmental cascades lens. Frontiers in psychology. vol 14. 2023-10-18. PMID:37849475. |
children with down syndrome (ds) typically have motor and language needs. |
2023-10-18 |
2023-11-08 |
Not clear |
| Aurore Thomazeau, Olivier Lassalle, Olivier J Manzon. Glutamatergic synaptic deficits in the prefrontal cortex of the Ts65Dn mouse model for Down syndrome. Frontiers in neuroscience. vol 17. 2023-10-16. PMID:37841687. |
down syndrome (ds), the most prevalent cause of intellectual disability, stems from a chromosomal anomaly resulting in an entire or partial extra copy of chromosome 21. |
2023-10-16 |
2023-11-08 |
mouse |
| Mara Dierssen, Cesar Sierra, Miguel Sabariego, Alvaro Fernández-Blanco, Sonia Cruciani, Alfonsa Zamora-Moratalla, Eva Maria Novo. The lncRNA Snhg11, a new candidate contributing to neurogenesis, plasticity and memory deficits in Down syndrome. Research square. 2023-10-16. PMID:37841843. |
down syndrome (ds) stands as the prevalent genetic cause of intellectual disability, yet comprehensive understanding of its cellular and molecular underpinnings remains limited. |
2023-10-16 |
2023-11-08 |
mouse |
| Mara Dierssen, Cesar Sierra, Miguel Sabariego, Alvaro Fernández-Blanco, Sonia Cruciani, Alfonsa Zamora-Moratalla, Eva Maria Novo. The lncRNA Snhg11, a new candidate contributing to neurogenesis, plasticity and memory deficits in Down syndrome. Research square. 2023-10-16. PMID:37841843. |
notably, reduced levels of snhg11 in this region were also observed in a distinct ds mouse model, the dp(16)1yey, as well as in human postmortem tissue, indicating its relevance in down syndrome. |
2023-10-16 |
2023-11-08 |
mouse |
| Marisha Shetty, Margot J Davey, Gillian M Nixon, Lisa M Walter, Rosemary S C Horn. Sleep spindles are reduced in children with Down syndrome and sleep-disordered breathing. Pediatric research. 2023-10-16. PMID:37845520. |
children with down syndrome (ds) are at increased risk of sleep-disordered breathing (sdb). |
2023-10-16 |
2023-11-08 |
Not clear |
| Afsary Jahan Khan, Tasin Afrose, Fowjia Ayesha Nuha, Muhammad Asiful Islam, Mas Suryalis Binti Ahma. Bruxism management in individuals with autism spectrum disorder and down syndrome - A systematic review. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. 2023-10-11. PMID:37817388. |
in dentistry, association between bruxism and individuals with autism spectrum disorders (asd) and down syndrome (ds) is high. |
2023-10-11 |
2023-10-15 |
Not clear |
| Macarena Jofré Urrutia, Paula Bedregal, Macarena Lizam. Adapting a quality of life scale for children and young people with Down syndrome in Chile. American journal of medical genetics. Part A. 2023-10-09. PMID:37807345. |
in chile, there are no validated instruments for the evaluation of quality of life (qol) of people with down syndrome (ds). |
2023-10-09 |
2023-10-15 |
Not clear |
| Federico Baldo, Allison Piovesan, Marijana Rakvin, Giuseppe Ramacieri, Chiara Locatelli, Silvia Lanfranchi, Sara Onnivello, Francesca Pulina, Maria Caracausi, Francesca Antonaros, Michele Lombardi, Maria Chiara Peller. Machine learning based analysis for intellectual disability in Down syndrome. Heliyon. vol 9. issue 9. 2023-10-09. PMID:37810082. |
down syndrome (ds) or trisomy 21 is the most common genetic cause of intellectual disability (id), but a pathogenic mechanism has not been identified yet. |
2023-10-09 |
2023-10-15 |
human |
| Julia S Mouat, Shaobo Li, Swe Swe Myint, Benjamin I Laufer, Philip J Lupo, Jeremy M Schraw, John P Woodhouse, Adam J de Smith, Janine M LaSall. Epigenomic signature of major congenital heart defects in newborns with Down syndrome. Human genomics. vol 17. issue 1. 2023-10-06. PMID:37803336. |
congenital heart defects (chds) affect approximately half of individuals with down syndrome (ds), but the molecular reasons for incomplete penetrance are unknown. |
2023-10-06 |
2023-10-15 |
Not clear |
| Hidehiro Suginobe, Hidekazu Ishida, Yoichiro Ishii, Kazutoshi Ueda, Chika Yoshihara, Atsuko Ueyama, Renjie Wang, Hirofumi Tsuru, Kazuhisa Hashimoto, Masaki Hirose, Ryo Ishii, Jun Narita, Yasuji Kitabatake, Keiichi Ozon. Isogenic pairs of induced-pluripotent stem-derived endothelial cells identify DYRK1A/PPARG/EGR1 pathway is responsible for Down syndrome-associated pulmonary hypertension. Human molecular genetics. 2023-10-04. PMID:37792788. |
down syndrome (ds) is the most prevalent chromosomal disorder associated with a higher incidence of pulmonary arterial hypertension (pah). |
2023-10-04 |
2023-10-07 |
human |
| Aline S G G Conceição, Lívea F G Sant Ana, Guilherme P Mattar, Maria de Fátima R Silva, Andressa R Ramos, Alexandra M Oliveira, Claudia L Carvalho, Octavio R Gonçalves, Bruna L R Varotto, Luana D Martinez, Vinícius Leduc, Luciana M Fonseca, Orestes V Forlenz. Balance and Gait: Associations With Cognitive Impairment and Dementia in Individuals With Down Syndrome. Alzheimer disease and associated disorders. 2023-10-03. PMID:37788381. |
atypical aging in down syndrome (ds) is associated with neuropathological characteristics consistent with alzheimer disease. |
2023-10-03 |
2023-10-07 |
Not clear |
| Beatriz Sánchez Moreno, Laura Adán-Lirola, Javier Rubio-Serrano, Diego Real de Asú. Causes of mortality among adults with Down syndrome before and after the COVID-19 pandemic in Spain. Journal of intellectual disability research : JIDR. 2023-10-02. PMID:37779228. |
the life expectancy of people with down syndrome (ds) is limited by alzheimer's disease (ad)-related deaths, mainly due to respiratory infections. |
2023-10-02 |
2023-10-07 |
Not clear |
| Ayesha Harisinghani, Gabriella Raffaele, Carrie Blout Zawatsky, Stephanie L Santor. Beyond chromosome analysis: Additional genetic testing practice in a Down syndrome clinic. American journal of medical genetics. Part C, Seminars in medical genetics. 2023-09-29. PMID:37774106. |
down syndrome (ds) and other genetic conditions have been reported to co-occur in the same person. |
2023-09-29 |
2023-10-07 |
Not clear |
| Kelley L Colvin, Kathleen Nguyen, Katie L Boncella, Desiree M Goodman, Robert J Elliott, Julie W Harral, Jill Bilodeaux, Bradford J Smith, Michael E Yeage. Lung and Heart Biology of the Dp16 Mouse Model of down Syndrome: Implications for Studying Cardiopulmonary Disease. Genes. vol 14. issue 9. 2023-09-28. PMID:37761959. |
(1) background: we sought to investigate the baseline lung and heart biology of the dp16 mouse model of down syndrome (ds) as a prelude to the investigation of recurrent respiratory tract infection. |
2023-09-28 |
2023-10-07 |
mouse |