| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura A Schieve, Sheree L Boulet, Michael D Kogan, Kim Van Naarden-Braun, Coleen A Boyl. A population-based assessment of the health, functional status, and consequent family impact among children with Down syndrome. Disability and health journal. vol 4. issue 2. 2011-08-25. PMID:21419370. |
many health conditions have been described in children with down syndrome (ds). |
2011-08-25 |
2023-08-12 |
Not clear |
| Louise D Bryant, Shenaz Ahmed, Mushtaq Ahmed, Hussain Jafri, Yasmin Raashi. 'All is done by Allah'. Understandings of Down syndrome and prenatal testing in Pakistan. Social science & medicine (1982). vol 72. issue 8. 2011-08-24. PMID:21470731. |
this study carried out in 2008 used q-methodology to characterize understandings of down syndrome (ds) in pakistan in a sample of health professionals, researchers and parents of children with the condition. |
2011-08-24 |
2023-08-12 |
human |
| Egambaram Senthilvel, Jyoti Krishn. Body position and obstructive sleep apnea in children with Down syndrome. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. vol 7. issue 2. 2011-08-24. PMID:21509330. |
children with down syndrome (ds) commonly have obstructive sleep apnea syndrome (osas) and may assume a unique sleeping position not systematically described previously. |
2011-08-24 |
2023-08-12 |
Not clear |
| D S Kern, K N Maclean, H Jiang, E Y Synder, J R Sladek, K B Bjugsta. Neural stem cells reduce hippocampal tau and reelin accumulation in aged Ts65Dn Down syndrome mice. Cell transplantation. vol 20. issue 3. 2011-08-23. PMID:20875225. |
tau accumulation, in the form of neurofibrillary tangles (nft), is an early neuropathological characteristic of alzheimer's disease (ad) and early onset ad frequently seen in down syndrome (ds). |
2011-08-23 |
2023-08-12 |
mouse |
| Joanna Smigielska-Kuzia, Leszek Boćkowski, Wojciech Sobaniec, Krzysztof Sendrowski, Beata Zelazowska-Rutkowska, Magdalena Cholew. Anti-inflammatory plasma cytokines in children and adolescents with Down syndrome. Folia histochemica et cytobiologica. vol 48. issue 4. 2011-08-19. PMID:21478113. |
production of some important cytokines in children with down syndrome (ds) is depressed or increased. |
2011-08-19 |
2023-08-12 |
human |
| Cristiani Cortez Mendes, Joice Matos Biselli, Bruna Lancia Zampieri, Eny Maria Goloni-Bertollo, Marcos Nogueira Eberlin, Renato Haddad, Maria Francesca Riccio, Hélio Vannucchi, Valdemir Melechco Carvalho, Erika Cristina Pavarino-Bertell. 19-base pair deletion polymorphism of the dihydrofolate reductase (DHFR) gene: maternal risk of Down syndrome and folate metabolism. Sao Paulo medical journal = Revista paulista de medicina. vol 128. issue 4. 2011-08-12. PMID:21120433. |
polymorphisms in genes involved in folate metabolism may modulate the maternal risk of down syndrome (ds). |
2011-08-12 |
2023-08-12 |
Not clear |
| Joanna Śmigielska-Kuzia, Leszek Boćkowski, Wojciech Sobaniec, Wojciech Kułak, Krzysztof Sendrowsk. Amino acid metabolic processes in the temporal lobes assessed by proton magnetic resonance spectroscopy (1H MRS) in children with Down syndrome. Pharmacological reports : PR. vol 62. issue 6. 2011-08-10. PMID:21273664. |
down syndrome (ds), or trisomy 21, is one of the most common autosomal mutations. |
2011-08-10 |
2023-08-12 |
Not clear |
| Goncalo V Mendonca, Fernando D Pereira, Bo Fernhal. Fractal scaling properties of heart rate dynamics in persons with Down syndrome. Autonomic neuroscience : basic & clinical. vol 161. issue 1-2. 2011-08-05. PMID:21333612. |
the purpose of this study was to evaluate the fractal heart rate dynamics in adults with down syndrome (ds) under different physiological conditions (rest, exercise and post-exercise recovery) and compare their responses with those of nondisabled individuals. |
2011-08-05 |
2023-08-12 |
human |
| Lucija Lujić, Vlatka Mejaski Bosnjak, Sanja Delin, Vlasta Duranović, Goran Kraka. Infantile spasms in children with Down syndrome. Collegium antropologicum. vol 35 Suppl 1. 2011-08-02. PMID:21648336. |
down syndrome (ds) is the most common genetic cause of mental retardation. |
2011-08-02 |
2023-08-12 |
Not clear |
| Rengasamy Sureshbabu, Rashmi Kumari, Subramaniam Ranugha, Ramanathan Sathyamoorthy, Carounanidy Udayashankar, Paquirissamy Oudeacouma. Phenotypic and dermatological manifestations in Down Syndrome. Dermatology online journal. vol 17. issue 2. 2011-07-27. PMID:21382286. |
down syndrome (ds) is associated with various uncommon dermatological disorders and increased frequency of some common dermatoses. |
2011-07-27 |
2023-08-12 |
Not clear |
| Stefania Trazzi, Valentina Maria Mitrugno, Emanuele Valli, Claudia Fuchs, Simona Rizzi, Sandra Guidi, Giovanni Perini, Renata Bartesaghi, Elisabetta Cian. APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. Human molecular genetics. vol 20. issue 8. 2011-07-21. PMID:21266456. |
mental retardation in down syndrome (ds) appears to be related to severe neurogenesis impairment during critical phases of brain development. |
2011-07-21 |
2023-08-12 |
mouse |
| May F Sadiq, Ekhlas A Al-Refai, Amjad Al-Nasser, Mohammad Khassawneh, Qasem Al-Batayne. Methylenetetrahydrofolate reductase polymorphisms C677T and A1298C as maternal risk factors for Down syndrome in Jordan. Genetic testing and molecular biomarkers. vol 15. issue 1-2. 2011-07-19. PMID:21198396. |
these polymorphisms are suggested to be risk factors for down syndrome (ds) in some populations. |
2011-07-19 |
2023-08-12 |
Not clear |
| Takashi Taga, Yasuto Shimomura, Yasuo Horikoshi, Atsushi Ogawa, Masaki Itoh, Masahiko Okada, Junichi Ueyama, Takeshi Higa, Arata Watanabe, Hirokazu Kanegane, Asayuki Iwai, Yutaka Saiwakawa, Kazuhiro Kogawa, Junko Yamanaka, Masahito Tsurusaw. Continuous and high-dose cytarabine combined chemotherapy in children with down syndrome and acute myeloid leukemia: Report from the Japanese children's cancer and leukemia study group (JCCLSG) AML 9805 down study. Pediatric blood & cancer. vol 57. issue 1. 2011-07-18. PMID:21557456. |
the aim of the jcclsg aml 9805 down study was to evaluate the effect of continuous and high-dose cytarabine combined chemotherapy on the survival outcome of acute myeloid leukemia (aml) with down syndrome (ds). |
2011-07-18 |
2023-08-12 |
Not clear |
| Deepali Jain, Tejinder Singh, Prerna Aror. Down syndrome with microgranular variant of acute promyelocytic leukemia in a child: a case report. Journal of medical case reports. vol 1. 2011-07-14. PMID:18036234. |
cases of apl in down syndrome (ds) have been described in the literature rarely and it is rarer still to find the microgranular variant (m3v) of apl in trisomy 21 patients. |
2011-07-14 |
2023-08-12 |
Not clear |
| Maria Luiza Macedo Silva, Maria do Socorro Pombo-de-Oliveira, Susana C Raimondi, Hasmik Mkrtchyan, Eliana Abdelhay, Amanda Faria de Figueiredo, Mariana Tavares de Souza, Daniela Ribeiro Ney Garcia, Eliane Maria Soares de Ventura, Adriana Martins de Sousa, Thomas Lieh. Unbalanced chromosome 1 abnormalities leading to partial trisomy 1q in four infants with Down syndrome and acute megakaryocytic leukemia. Molecular cytogenetics. vol 2. 2011-07-14. PMID:19228396. |
children with down syndrome (ds) have an increased risk of childhood acute leukemia, especially acute megakaryoblastic leukemia (amkl) also called acute myeloid leukemia (aml) type m7. |
2011-07-14 |
2023-08-12 |
Not clear |
| Maj A Hultén, Suketu D Patel, Magnus Westgren, Nikos Papadogiannakis, Anna Maria Jonsson, Jon Jonasson, Erik Iwarsso. On the paternal origin of trisomy 21 Down syndrome. Molecular cytogenetics. vol 3. 2011-07-14. PMID:20178584. |
down syndrome (ds), characterized by an extra free chromosome 21 is the most common genetic cause for congenital malformations and learning disability. |
2011-07-14 |
2023-08-12 |
Not clear |
| Natalia V Kovalev. Germ-line transmission of trisomy 21: Data from 80 families suggest an implication of grandmaternal age and a high frequency of female-specific trisomy rescue. Molecular cytogenetics. vol 3. 2011-07-14. PMID:20298592. |
trisomy of chromosome 21 (t21; down syndrome, ds) is the most common aneuploidy in live births. |
2011-07-14 |
2023-08-12 |
Not clear |
| Cyrus Cyril, Padmalatha Rai, N Chandra, P M Gopinath, K Satyamoorth. MTHFR Gene variants C677T, A1298C and association with Down syndrome: A Case-control study from South India. Indian journal of human genetics. vol 15. issue 2. 2011-07-14. PMID:20680153. |
trisomy 21 or down syndrome (ds) is the most common genetic cause of mental retardation. |
2011-07-14 |
2023-08-12 |
Not clear |
| Lee A Shapiro, Lynn A Bialowas-McGoey, Patricia M Whitaker-Azmiti. Effects of S100B on Serotonergic Plasticity and Neuroinflammation in the Hippocampus in Down Syndrome and Alzheimer's Disease: Studies in an S100B Overexpressing Mouse Model. Cardiovascular psychiatry and neurology. vol 2010. 2011-07-14. PMID:20827311. |
both of these processes are therefore accelerated towards degeneration in disease processes wherein s100b is increased, notably, alzheimer's disease (ad) and down syndrome (ds). |
2011-07-14 |
2023-08-12 |
mouse |
| Abhay Sharm. Transcriptome bioinformatic analysis identifies potential therapeutic mechanism of pentylenetetrazole in down syndrome. BioData mining. vol 3. issue 1. 2011-07-14. PMID:21029440. |
pentylenetetrazole (ptz) has recently been found to ameliorate cognitive impairment in rodent models of down syndrome (ds). |
2011-07-14 |
2023-08-12 |
drosophila_melanogaster |