| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth Head, Eric Doran, Mihaela Nistor, MaryAnn Hill, Frederick A Schmitt, Richard J Haier, Ira T Lot. Plasma amyloid-β as a function of age, level of intellectual disability, and presence of dementia in Down syndrome. Journal of Alzheimer's disease : JAD. vol 23. issue 3. 2011-12-20. PMID:21116050. |
adults with down syndrome (ds) are at risk for developing alzheimer's disease (ad). |
2011-12-20 |
2023-08-12 |
human |
| Nathalie Jeanne Magioli Bravo-Valenzuela, Maria Lucia Bastos Passarelli, Maria Veronica Coates, Luiz Fernando Costa Nasciment. Weight and height recovery in children with Down syndrome and congenital heart disease. Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular. vol 26. issue 1. 2011-12-20. PMID:21881713. |
to evaluate the impact of congenital heart diseases in growth of children with down syndrome (ds) and the weight-height recovery after surgical correction. |
2011-12-20 |
2023-08-12 |
Not clear |
| Joanna Smigielska-Kuzia, Leszek Boćkowski, Wojciech Sobaniec, Krzysztof Sendrowski, Beata Olchowik, Magdalena Cholewa, Adam Lukasiewicz, Urszula Lebkowsk. A volumetric magnetic resonance imaging study of brain structures in children with Down syndrome. Neurologia i neurochirurgia polska. vol 45. issue 4. 2011-12-20. PMID:22101997. |
down syndrome (ds) is the most common genetic cause of mental retardation with deficits in language and memory. |
2011-12-20 |
2023-08-12 |
Not clear |
| Deny Menghini, Floriana Costanzo, Stefano Vicar. Relationship between brain and cognitive processes in Down syndrome. Behavior genetics. vol 41. issue 3. 2011-12-15. PMID:21279430. |
we investigated regional grey matter (gm) density in adolescents with down syndrome (ds) compared to age-matched controls and correlated mri data with neuropsychological measures in the ds group. |
2011-12-15 |
2023-08-12 |
human |
| Stamatis Agiovlasitis, Robert W Motl, Sushant M Ranadive, Christopher A Fahs, Huimin Yan, George H Echols, Lindy Rossow, Bo Fernhal. Prediction of oxygen uptake during over-ground walking in people with and without Down syndrome. European journal of applied physiology. vol 111. issue 8. 2011-12-13. PMID:21221988. |
the reduced gait stability and aerobic fitness of people with down syndrome (ds) may increase their rate of gross oxygen uptake (gross-vo(2)) during over-ground walking. |
2011-12-13 |
2023-08-12 |
human |
| J Braudeau, B Delatour, A Duchon, P Lopes Pereira, L Dauphinot, F de Chaumont, J-C Olivo-Marin, R H Dodd, Y Hérault, M-C Potie. Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice. Journal of psychopharmacology (Oxford, England). vol 25. issue 8. 2011-12-13. PMID:21693554. |
an imbalance between inhibitory and excitatory neurotransmission has been proposed to contribute to altered brain function in individuals with down syndrome (ds). |
2011-12-13 |
2023-08-12 |
mouse |
| Chunhong Liu, Masae Morishima, Tao Yu, Sei-Ichi Matsui, Li Zhang, Dawei Fu, Annie Pao, Alberto C Costa, Katheleen J Gardiner, John K Cowell, Norma J Nowak, Normal J Nowak, Michael S Parmacek, Ping Liang, Antonio Baldini, Y Eugene Y. Genetic analysis of Down syndrome-associated heart defects in mice. Human genetics. vol 130. issue 5. 2011-12-08. PMID:21442329. |
human trisomy 21, the chromosomal basis of down syndrome (ds), is the most common genetic cause of heart defects. |
2011-12-08 |
2023-08-12 |
mouse |
| Helma B M van Gameren-Oosterom, Minne Fekkes, Simone E Buitendijk, Ashna D Mohangoo, Jeanet Bruil, Jacobus P Van Wouw. Development, problem behavior, and quality of life in a population based sample of eight-year-old children with Down syndrome. PloS one. vol 6. issue 7. 2011-12-08. PMID:21814560. |
children with down syndrome (ds) have delayed psychomotor development. |
2011-12-08 |
2023-08-12 |
Not clear |
| Ana Cristina Oliveira, Saul Martins Paiva, Milene Torres Martins, Cintia Silva Torres, Isabela Almeida Pordeu. Prevalence and determinant factors of malocclusion in children with special needs. European journal of orthodontics. vol 33. issue 4. 2011-12-06. PMID:20956386. |
the present study analysed the prevalence of malocclusion in children with down syndrome (ds) and cerebral palsy (cp) as well as associations with individual, socio-economic, and behavioural factors. |
2011-12-06 |
2023-08-12 |
Not clear |
| Dale A Ulrich, Amy R Burghardt, Meghann Lloyd, Chad Tiernan, Joseph E Hornya. Physical activity benefits of learning to ride a two-wheel bicycle for children with Down syndrome: a randomized trial. Physical therapy. vol 91. issue 10. 2011-12-06. PMID:21852519. |
people with down syndrome (ds) display consistent patterns of physical inactivity. |
2011-12-06 |
2023-08-12 |
Not clear |
| P N A C M van Heesch, Y B de Rijke, J A M Laudy, H I J Wildschu. Erroneous production of PAPP-A kits: the impact of a downward shift in PAPP-A concentration on the test performance of first-trimester combined screening for Down syndrome. Prenatal diagnosis. vol 31. issue 8. 2011-12-01. PMID:21692091. |
to evaluate a 20% downward shift in the pregnancy-associated plasma protein a (papp-a) concentration on the test performance of first-trimester combined screening (fts) for down syndrome (ds) following a flaw in the production of papp-a kits on fts for ds. |
2011-12-01 |
2023-08-12 |
Not clear |
| Osman Demirhan, Deniz Taştemir, Ramazan Güneşaçar, Ali İrfan Güzel, Davut Alpteki. The first report described as an important study: The association of mannose-binding lectin gene 2 polymorphisms in children with Down syndrome. Indian journal of human genetics. vol 17. issue 2. 2011-11-23. PMID:22090714. |
mannose-binding lectin gene 2 (mbl2) plays a very important role in the first line of host immune response in down syndrome (ds). |
2011-11-23 |
2023-08-12 |
Not clear |
| A González-Agüero, G Vicente-Rodríguez, L A Moreno, J A Casajú. Bone mass in male and female children and adolescents with Down syndrome. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. vol 22. issue 7. 2011-11-22. PMID:20967423. |
children and adolescents with down syndrome (ds) have lower levels of bone mass compared with youths without ds. |
2011-11-22 |
2023-08-12 |
Not clear |
| Carlos Campos, Rodrigo Guzmán, Encarnación López-Fernández, Angela Casad. Evaluation of urinary biomarkers of oxidative/nitrosative stress in children with Down syndrome. Life sciences. vol 89. issue 17-18. 2011-11-22. PMID:21871905. |
it has been suggested that oxidative stress plays a key role in the pathogenesis of down syndrome (ds). |
2011-11-22 |
2023-08-12 |
Not clear |
| M G Loudin, J Wang, H-C Eastwood Leung, S Gurusiddappa, J Meyer, G Condos, D Morrison, A Tsimelzon, M Devidas, N A Heerema, A J Carroll, S E Plon, S P Hunger, G Basso, A Pession, D Bhojwani, W L Carroll, K R Rabi. Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles. Leukemia. vol 25. issue 10. 2011-11-21. PMID:21647151. |
patients with down syndrome (ds) and acute lymphoblastic leukemia (all) have distinct clinical and biological features. |
2011-11-21 |
2023-08-12 |
Not clear |
| Stamatis Agiovlasitis, Kenneth H Pitetti, Myriam Guerra, Bo Fernhal. Prediction of VO2peak from the 20-m shuttle-run test in youth with Down syndrome. Adapted physical activity quarterly : APAQ. vol 28. issue 2. 2011-11-18. PMID:21757786. |
this study examined whether 20-m shuttle-run performance, sex, body mass index (bmi), age, height, and weight are associated with peak oxygen uptake (vo2peak) in youth with down syndrome (ds; n = 53; 25 women, age 8-20 years) and whether these variables can be used to develop an equation to predict vo2peak. |
2011-11-18 |
2023-08-12 |
Not clear |
| François Mouton-Liger, Sophie Thomas, Revital Rattenbach, Laetitia Magnol, Vanessa Larigaldie, Aurelie Ledru, Yann Herault, Catherine Verney, Nicole Créa. PCP4 (PEP19) overexpression induces premature neuronal differentiation associated with Ca(2+) /calmodulin-dependent kinase II-δ activation in mouse models of Down syndrome. The Journal of comparative neurology. vol 519. issue 14. 2011-11-15. PMID:21491429. |
the pcp4 gene is located on human chromosome 21 and is present in three copies in down syndrome (ds). |
2011-11-15 |
2023-08-12 |
mouse |
| b' M Bertoli, G Biasini, M T Calignano, G Celani, G De Grossi, M C Digilio, C C Fermariello, G Loffredo, F Luchino, A Marchese, S Mazotti, B Menghi, C Razzano, C Tiano, A Zambon Hobart, G Zampino, G Zuccal\\xc3\\xa. Needs and challenges of daily life for people with Down syndrome residing in the city of Rome, Italy. Journal of intellectual disability research : JIDR. vol 55. issue 8. 2011-11-15. PMID:21668802.' |
population-based surveys on the quality of life of people with down syndrome (ds) are difficult to perform because of ethical and legal policies regarding privacy and confidential information, but they are essential for service planning. |
2011-11-15 |
2023-08-12 |
Not clear |
| Jie Lu, Giuseppe Esposito, Caterina Scuderi, Luca Steardo, Laurent C Delli-Bovi, Jonathan L Hecht, Bryan C Dickinson, Christopher J Chang, Takashi Mori, Volney Shee. S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors. PloS one. vol 6. issue 7. 2011-11-15. PMID:21779383. |
down syndrome (ds) is a developmental disorder associated with mental retardation (mr) and early onset alzheimer's disease (ad). |
2011-11-15 |
2023-08-12 |
human |
| Renata Bartesaghi, Sandra Guidi, Elisabetta Cian. Is it possible to improve neurodevelopmental abnormalities in Down syndrome? Reviews in the neurosciences. vol 22. issue 4. 2011-11-15. PMID:21819263. |
down syndrome (ds) is a genetic pathology caused by the triplication of human chromosome 21. |
2011-11-15 |
2023-08-12 |
mouse |