| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anne Ronan, Kerry Fagan, Louise Christie, Jeffrey Conroy, Norma J Nowak, Gillian Turne. Familial 4.3 Mb duplication of 21q22 sheds new light on the Down syndrome critical region. BMJ case reports. vol 2009. 2011-11-10. PMID:21686961. |
all had the facial gestalt of down syndrome (ds). |
2011-11-10 |
2023-08-12 |
Not clear |
| Wendy E Heywood, Tracey E Madgett, Darrell Wang, Amanda Wallington, Julie Hogg, Kevin Mills, Neil D Aven. 2D DIGE analysis of maternal plasma for potential biomarkers of Down Syndrome. Proteome science. vol 9. 2011-11-10. PMID:21929753. |
prenatal screening for down syndrome (ds) would benefit from an increased number of biomarkers to improve sensitivity and specificity. |
2011-11-10 |
2023-08-12 |
Not clear |
| Suttur S Malini, Nallur B Ramachandr. Possible risk factors for Down syndrome and sex chromosomal aneuploidy in Mysore, South India. Indian journal of human genetics. vol 13. issue 3. 2011-11-10. PMID:21957357. |
down syndrome (ds) and sex chromosomal aneuploidy (sa) are common chromosomal anomalies causing congenital malformations and mental retardation in humans. |
2011-11-10 |
2023-08-12 |
Not clear |
| Daniela Neagos, Ruxandra Cretu, Andreea Tutulan-Cunita, Veronica Stoian, Laurentiu Camil Bohilte. RFC - 1 Gene Polymorphism and the Risk of Down Syndrome in Romanian Population. Maedica. vol 5. issue 4. 2011-11-10. PMID:21977171. |
there is evidence that the polymorphisms of the genes involved in folate metabolism may be associated with higher risk of down syndrome (ds) pregnancy. |
2011-11-10 |
2023-08-12 |
Not clear |
| D-W Kim, H-R Kim, M-G Shin, H-J Baek, H Kook, T-J Hwang, J-H Shin, S-P Suh, D-W Ryan. Distinctive hematological abnormalities in East Asian neonates and children with Down syndrome. International journal of laboratory hematology. vol 33. issue 4. 2011-11-09. PMID:21692995. |
neonates with down syndrome (ds) are predisposed to developing transient abnormal myelopoiesis (tam) and acute myeloid leukemia (aml) associated with ds. |
2011-11-09 |
2023-08-12 |
Not clear |
| Flavia A Lima, Carlos A Moreira-Filho, Patrícia L Ramos, Helena Brentani, Leandro de A Lima, Magaly Arrais, Luiz C Bento-de-Souza, Luciana Bento-de-Souza, Maria I Duarte, Antonio Coutinho, Magda Carneiro-Sampai. Decreased AIRE expression and global thymic hypofunction in Down syndrome. Journal of immunology (Baltimore, Md. : 1950). vol 187. issue 6. 2011-11-09. PMID:21856934. |
the down syndrome (ds) immune phenotype is characterized by thymus hypotrophy, higher propensity to organ-specific autoimmune disorders, and higher susceptibility to infections, among other features. |
2011-11-09 |
2023-08-12 |
Not clear |
| Ashok Patel, Simon D Rees, M Ann Kelly, Steven C Bain, Anthony H Barnett, Deepak Thalitaya, Vee P Prashe. Association of variants within APOE, SORL1, RUNX1, BACE1 and ALDH18A1 with dementia in Alzheimer's disease in subjects with Down syndrome. Neuroscience letters. vol 487. issue 2. 2011-11-08. PMID:20946940. |
down syndrome (ds) is caused by either complete or partial triplication of chromosome 21, affecting approximately 1/1000 live births, and it is widely accepted that individuals with ds are more likely to develop dementia of alzheimer's disease (dad) compared with the general population. |
2011-11-08 |
2023-08-12 |
human |
| Candice G Lorandeau, Lauren A Hakkinen, Clara S Moor. Cardiovascular development and survival during gestation in the Ts65Dn mouse model for Down syndrome. Anatomical record (Hoboken, N.J. : 2007). vol 294. issue 1. 2011-11-07. PMID:21157920. |
the ts65dn mouse model for down syndrome (ds) exhibits many phenotypes seen in human ds. |
2011-11-07 |
2023-08-12 |
mouse |
| Ahmed Khocht, Kevin Heaney, Malvin Janal, Bobby Turne. Association of interleukin-1 polymorphisms with periodontitis in Down syndrome. Journal of oral science. vol 53. issue 2. 2011-11-03. PMID:21712624. |
this study examined the association of il1 genetic polymorphisms (il-1a +4845, il-1b +3954 & il-1rn +2018) with periodontal disease status of down syndrome (ds) individuals. |
2011-11-03 |
2023-08-12 |
human |
| Hong-Ning Xie, Yun-Xiao Zhu, Li-Juan Li, Hua H. [Ultrasonographic fetal nasal bone assessment in prenatal screening for Down syndrome]. Zhonghua fu chan ke za zhi. vol 43. issue 3. 2011-10-28. PMID:18788563. |
to investigate the clinic value of ultrasonographic fetal nasal bone examination as a screening marker for down syndrome (ds). |
2011-10-28 |
2023-08-12 |
Not clear |
| Stamatis Agiovlasitis, Robert W Motl, Christopher A Fahs, Sushant M Ranadive, Huimin Yan, George H Echols, Lindy Rossow, Bo Fernhal. Metabolic rate and accelerometer output during walking in people with Down syndrome. Medicine and science in sports and exercise. vol 43. issue 7. 2011-10-28. PMID:21200346. |
people with down syndrome (ds) have reduced gait stability and aerobic fitness that increase the metabolic rate during walking, potentially altering the relationship between metabolic rate and accelerometer output and lowering predictability of energy expenditure from accelerometry. |
2011-10-28 |
2023-08-12 |
Not clear |
| Marzia Perluigi, Fabio di Domenico, Ada Fiorini, Annalisa Cocciolo, Alessandra Giorgi, Cesira Foppoli, D Allan Butterfield, Maurizio Giorlandino, Claudio Giorlandino, M Eugenia Schininà, Raffaella Cocci. Oxidative stress occurs early in Down syndrome pregnancy: A redox proteomics analysis of amniotic fluid. Proteomics. Clinical applications. vol 5. issue 3-4. 2011-10-25. PMID:21360684. |
the present study aims to evaluate a set of oxidative stress biomarkers in the amniotic fluid (af) of women carrying down syndrome (ds) fetuses that could prove in vivo the early occurrence of oxidative damage in ds. |
2011-10-25 |
2023-08-12 |
Not clear |
| Alina V Dumitrescu, Daniela C Moga, Susannah Q Longmuir, Richard J Olson, Arlene V Drac. Prevalence and characteristics of abnormal head posture in children with Down syndrome: a 20-year retrospective, descriptive review. Ophthalmology. vol 118. issue 9. 2011-10-24. PMID:21665280. |
to characterize the abnormal head posture (ahp) in children with down syndrome (ds). |
2011-10-24 |
2023-08-12 |
Not clear |
| Kate A Alford, Katarina Reinhardt, Catherine Garnett, Alice Norton, Katarina Böhmer, Christine von Neuhoff, Alexandra Kolenova, Emanuele Marchi, Jan-Henning Klusmann, Irene Roberts, Henrik Hasle, Dirk Reinhardt, Paresh Vya. Analysis of GATA1 mutations in Down syndrome transient myeloproliferative disorder and myeloid leukemia. Blood. vol 118. issue 8. 2011-10-24. PMID:21715302. |
children with down syndrome (ds) up to the age of 4 years are at a 150-fold excess risk of developing myeloid leukemia (ml-ds). |
2011-10-24 |
2023-08-12 |
Not clear |
| Yan Wang, Junning Wang, Lei Gao, Stefan Stamm, Athena Andreadi. An SRp75/hnRNPG complex interacting with hnRNPE2 regulates the 5' splice site of tau exon 10, whose misregulation causes frontotemporal dementia. Gene. vol 485. issue 2. 2011-10-24. PMID:21723381. |
tauopathies include alzheimer's disease (ad), frontotemporal dementia with parkinsonism (ftdp-17), the early onset dementia observed in down syndrome (ds; trisomy 21) and the dementia component of myotonic dystrophy type 1 (dm1). |
2011-10-24 |
2023-08-12 |
Not clear |
| Zh M Shagirova, L A Kurbatova, L V Shulenina, A N Semiachkina, V F Mikhaĭlov, G D Zasukhin. [The peculiarities of polymorphism of XPD and XRCC1 repair genes in cells of Down and Ehlers-Danlo syndrome patients characterized by increased radiosensitivity]. Radiatsionnaia biologiia, radioecologiia. vol 51. issue 4. 2011-10-24. PMID:21950097. |
codon 312 and 751 polymorphisms ofxpd gene and codon 399 polymorphism of xrcc1 gene of peripheral blood lymphocytes in patients with down syndrome (ds) (46 individuals), ehlers-danlo syndrome (eds) (47 individuals) and in a group of healthy donors (control) (40 individuals) have been studied. |
2011-10-24 |
2023-08-12 |
Not clear |
| Ragaa R Hamed, Tahany M Maharem, Nagwa Abdel-Meguid, Gilane M Sabry, Abdel-Monem Abdalla, Rasha A Guneid. Purification and biochemical characterization of glutathione S-transferase from Down syndrome and normal children erythrocytes: a comparative study. Research in developmental disabilities. vol 32. issue 5. 2011-10-19. PMID:21377322. |
down syndrome (ds) is the phenotypic manifestation of trisomy 21. |
2011-10-19 |
2023-08-12 |
Not clear |
| Ragaa R Hamed, Tahany M Maharem, Nagwa Abdel-Meguid, Gilane M Sabry, Abdel-Monem Abdalla, Rasha A Guneid. Purification and biochemical characterization of glutathione S-transferase from Down syndrome and normal children erythrocytes: a comparative study. Research in developmental disabilities. vol 32. issue 5. 2011-10-19. PMID:21377322. |
our study was concerned with the characterization and purification of glutathione s-transferase enzyme (gst) from normal and down syndrome (ds) erythrocytes to illustrate the difference in the role of this enzyme in the cell. |
2011-10-19 |
2023-08-12 |
Not clear |
| J C Walker, A Dosen, J K Buitelaar, J G E Janzin. Depression in Down syndrome: a review of the literature. Research in developmental disabilities. vol 32. issue 5. 2011-10-19. PMID:21392935. |
depression has been frequently reported in individuals with down syndrome (ds). |
2011-10-19 |
2023-08-12 |
Not clear |
| R L Carvalho, G L Almeid. The effect of galvanic vestibular stimulation on postural response of Down syndrome individuals on the seesaw. Research in developmental disabilities. vol 32. issue 5. 2011-10-19. PMID:21420275. |
in order to better understand the role of the vestibular system in postural adjustments on unstable surfaces, we analyzed the effects of galvanic vestibular stimulation (gvs) on the pattern of muscle activity and joint displacements (ankle knee and hip) of eight intellectually normal participants (control group--cg) and eight control group individuals with down syndrome (ds) while balancing on seesaws of different heights. |
2011-10-19 |
2023-08-12 |
human |