| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emma L Jones, Clive G Ballard, Vee P Prasher, Matthew Arno, Stephen Tyrer, Brian Moore, Maria Luisa Hanne. An Intron 7 Polymorphism in APP Affects the Age of Onset of Dementia in Down Syndrome. International journal of Alzheimer's disease. vol 2011. 2011-07-14. PMID:21197396. |
people with down syndrome (ds) develop alzheimer's disease (ad) with an early age of onset. |
2011-07-14 |
2023-08-12 |
Not clear |
| Goncalo V Mendonca, Fernando D Pereira, Bo Fernhal. Reduced exercise capacity in persons with Down syndrome: cause, effect, and management. Therapeutics and clinical risk management. vol 6. 2011-07-14. PMID:21206759. |
persons with down syndrome (ds) have reduced peak and submaximal exercise capacity. |
2011-07-14 |
2023-08-12 |
Not clear |
| Maria Bf Trotta, João B Serro Azul, Mauricio Wajngarten, Simone G Fonseca, Anna C Goldberg, Jorge E Kali. Inflammatory and Immunological parameters in adults with Down syndrome. Immunity & ageing : I & A. vol 8. issue 1. 2011-07-14. PMID:21496308. |
the increase in life expectancy within the general population has resulted in an increasing number of elderly adults, including patients with down syndrome (ds), with a current life expectancy of about 50 years. |
2011-07-14 |
2023-08-12 |
Not clear |
| Maria Bf Trotta, João B Serro Azul, Mauricio Wajngarten, Simone G Fonseca, Anna C Goldberg, Jorge E Kali. Inflammatory and Immunological parameters in adults with Down syndrome. Immunity & ageing : I & A. vol 8. issue 1. 2011-07-14. PMID:21496308. |
the study group consisted of adults ds (n = 24) and a control group with intellectual disability without down syndrome (id) (n = 21) and living in a similar environmental background. |
2011-07-14 |
2023-08-12 |
Not clear |
| b' Francesco Macchini, Ernesto Leva, Maurizio Torricelli, Alberto Valad\\xc3\\xa. Treating acid reflux disease in patients with Down syndrome: pharmacological and physiological approaches. Clinical and experimental gastroenterology. vol 4. 2011-07-14. PMID:21694868.' |
down syndrome (ds) is often accompanied by gastrointestinal disease, occurring mainly in early infancy and frequently requiring therapy. |
2011-07-14 |
2023-08-12 |
Not clear |
| Carlos Campos, Rodrigo Guzmán, Encarnación López-Fernández, Angela Casad. Evaluation of urinary biomarkers of oxidative/nitrosative stress in adolescents and adults with Down syndrome. Biochimica et biophysica acta. vol 1812. issue 7. 2011-07-12. PMID:21447387. |
urinary biomarkers of oxidative stress have been little studied in adults with down syndrome (ds), usually no more than two biomarkers have been measured in the population studied and controversial results are reported in literature. |
2011-07-12 |
2023-08-12 |
Not clear |
| Ravindra Arya, Madhulika Kabra, Sheffali Gulat. Epilepsy in children with Down syndrome. Epileptic disorders : international epilepsy journal with videotape. vol 13. issue 1. 2011-07-08. PMID:21398208. |
this review discusses the various aspects of epilepsy in down syndrome (ds) from the perspective of paediatric neurology. |
2011-07-08 |
2023-08-12 |
Not clear |
| Yong-Lin Jia, Li-Jun Jing, Jin-Yi Li, Jing-Jing Lu, Rui Han, Shu-Yang Wang, Tao Peng, Yan-Jie Ji. Expression and significance of DSCAM in the cerebral cortex of APP transgenic mice. Neuroscience letters. vol 491. issue 2. 2011-07-05. PMID:21241773. |
overexpression of dscam in down syndrome (ds) may be involved in the pathogenesis of mental retardation through an inhibitory action on synaptogenesis/neurite outgrowth, and in the precocious dementia associated with an amyloid precursor protein (app) dosage effect with enhanced plaque formation. |
2011-07-05 |
2023-08-12 |
mouse |
| Victor I Popov, Alexander M Kleschevnikov, Oleg A Klimenko, Michael G Stewart, Pavel V Belichenk. Three-dimensional synaptic ultrastructure in the dentate gyrus and hippocampal area CA3 in the Ts65Dn mouse model of Down syndrome. The Journal of comparative neurology. vol 519. issue 7. 2011-07-01. PMID:21452200. |
down syndrome (ds) results from trisomy of human chromosome 21. |
2011-07-01 |
2023-08-12 |
mouse |
| J O Edgin, A Kumar, G Spanò, L Nade. Neuropsychological effects of second language exposure in Down syndrome. Journal of intellectual disability research : JIDR. vol 55. issue 3. 2011-06-28. PMID:21320223. |
past studies have not found differences on language tasks in children with down syndrome (ds) and sle. |
2011-06-28 |
2023-08-12 |
Not clear |
| M Elizabeth N Lewis, Michael W L Gauderer, Dawn W Blackhurst, R Curtis Rogers, Wendy R Cornet. Do patients with Down syndrome develop appendicitis? Journal of pediatric surgery. vol 46. issue 1. 2011-06-27. PMID:21238666. |
given the number of individuals with down syndrome (ds) and the high incidence of acute appendicitis (aa) in the general population, one would expect a certain number of patients with ds to develop aa. |
2011-06-27 |
2023-08-12 |
Not clear |
| Yanwei Sun, Mara Dierssen, Nuria Toran, Daniela D Pollak, Wei-Qiang Chen, Gert Lube. A gel-based proteomic method reveals several protein pathway abnormalities in fetal Down syndrome brain. Journal of proteomics. vol 74. issue 4. 2011-06-21. PMID:21262400. |
a large series of protein pathway components have been shown to be dysregulated in down syndrome (ds) brain. |
2011-06-21 |
2023-08-12 |
Not clear |
| Darren R Hocking, Nicole J Rinehart, Jennifer L McGinley, Simon A Moss, John L Bradsha. A kinematic analysis of visually-guided movement in Williams syndrome. Journal of the neurological sciences. vol 301. issue 1-2. 2011-06-17. PMID:21095618. |
we used a variant of the fitts' reciprocal aiming task on a computerized touchscreen in adults with ws, iq-matched individuals with down syndrome (ds), and typically developing controls. |
2011-06-17 |
2023-08-12 |
Not clear |
| Dennis Rosen, Angela Lombardo, Brian Skotko, Emily Jean Davidso. Parental perceptions of sleep disturbances and sleep-disordered breathing in children with Down syndrome. Clinical pediatrics. vol 50. issue 2. 2011-06-16. PMID:21098528. |
children with down syndrome (ds) have increased difficulty initiating and maintaining sleep (dims), excessive daytime sleepiness (eds), and obstructive sleep apnea (osa). |
2011-06-16 |
2023-08-12 |
Not clear |
| Beatrijs L P Bloemers, Louis Bont, Roel A de Weger, Sigrid A Otto, Jose A Borghans, Kiki Tesselaa. Decreased thymic output accounts for decreased naive T cell numbers in children with Down syndrome. Journal of immunology (Baltimore, Md. : 1950). vol 186. issue 7. 2011-06-16. PMID:21346234. |
children with down syndrome (ds) have low numbers of naive t cells and abnormal thymus development and function. |
2011-06-16 |
2023-08-12 |
Not clear |
| Goncalo V Mendonca, Fernando D Pereira, Bo Fernhal. Cardiac autonomic function during submaximal treadmill exercise in adults with Down syndrome. Research in developmental disabilities. vol 32. issue 2. 2011-06-14. PMID:21236635. |
this study determined whether the cardiac autonomic function of adults with down syndrome (ds) differs from that of nondisabled persons during submaximal dynamic exercise. |
2011-06-14 |
2023-08-12 |
human |
| G Ram, J Chine. Infections and immunodeficiency in Down syndrome. Clinical and experimental immunology. vol 164. issue 1. 2011-06-14. PMID:21352207. |
down syndrome (ds) is the most common genetic disease and presents with cognitive impairment, cardiac and gastrointestinal abnormalities, in addition to other miscellaneous clinical conditions. |
2011-06-14 |
2023-08-12 |
human |
| Ana Paula Carneiro Brandalize, Eliane Bandinelli, Pollyanna Almeida Dos Santos, Lavínia Schüler-Faccin. Maternal gene polymorphisms involved in folate metabolism as risk factors for Down syndrome offspring in Southern Brazil. Disease markers. vol 29. issue 2. 2011-06-13. PMID:21045269. |
this study aimed to investigate the role of maternal polymorphisms, as well as their risk genotypes combinations of mtr a2756g, mtrr a66g, cbs 844ins68, and rfc a80g, involved in folate/homocysteine metabolism, as possible risk factors for down syndrome (ds) in southern brazil. |
2011-06-13 |
2023-08-12 |
Not clear |
| Martina Blank, Peter G Fuerst, Beth Stevens, Navid Nouri, Lowry Kirkby, Deepti Warrier, Ben A Barres, Marla B Feller, Andrew D Huberman, Robert W Burgess, Craig C Garne. The Down syndrome critical region regulates retinogeniculate refinement. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490218. |
down syndrome (ds) is a developmental disorder caused by a third chromosome 21 in humans (trisomy 21), leading to neurological deficits and cognitive impairment. |
2011-06-13 |
2023-08-12 |
mouse |
| M F Urban, C Stewart, T Ruppelt, L Geert. Effectiveness of prenatal screening for Down syndrome on the basis of maternal age in Cape Town. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. vol 101. issue 1. 2011-06-09. PMID:21626982. |
the prenatal screening programme for down syndrome (ds) in the south african public health sector remains primarily based on advanced maternal age (ama). |
2011-06-09 |
2023-08-12 |
Not clear |