| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong-Mei Qiu, Jun-Xia Yang, Xiao-Hong Wu, Na Li, Dan Liu, Li-Jia Wang, Li-Juan Qin, Qi-Xin Zho. Antidepressive effect of paroxetine in a rat model: upregulating expression of serotonin and norepinephrine transporter. Neuroreport. vol 24. issue 10. 2014-01-10. PMID:23636256. |
paroxetine is a selective serotonin reuptake inhibitor used for the treatment of depression; this study investigated its other mechanisms by studying the expression and therefore involvement of norepinephrine transporter (net) and serotonin transporter (5-htt). |
2014-01-10 |
2023-08-12 |
rat |
| Masayuki Fujiwara, Hikaru Yamamoto, Tatsuhiro Miyagi, Takahiro Seki, Shigeru Tanaka, Izumi Hide, Norio Saka. Effects of the chemical chaperone 4-phenylbutylate on the function of the serotonin transporter (SERT) expressed in COS-7 cells. Journal of pharmacological sciences. vol 122. issue 2. 2014-01-09. PMID:23676312. |
the serotonin transporter (sert) is involved in various psychiatric disorders, including depression and autism. |
2014-01-09 |
2023-08-12 |
Not clear |
| Cristina Stasi, Massimo Rosselli, Anna Linda Zignego, Giacomo Laffi, Stefano Milan. Serotonin and its implication in the side-effects of interferon-based treatment of patients with chronic viral hepatitis: Pharmacological interventions. Hepatology research : the official journal of the Japan Society of Hepatology. vol 44. issue 1. 2014-01-06. PMID:23607322. |
emerging evidence suggests that interferon may cause depression affecting serotonin synthesis via increased activity of indoleamine 2,3-dioxygenase. |
2014-01-06 |
2023-08-12 |
Not clear |
| Cristina Stasi, Massimo Rosselli, Anna Linda Zignego, Giacomo Laffi, Stefano Milan. Serotonin and its implication in the side-effects of interferon-based treatment of patients with chronic viral hepatitis: Pharmacological interventions. Hepatology research : the official journal of the Japan Society of Hepatology. vol 44. issue 1. 2014-01-06. PMID:23607322. |
serotonin reuptake inhibitors significantly improve mood disorders, but the use of these drugs requires caution because some studies reported the emergence of mania in patients treated for depression during antiviral therapy. |
2014-01-06 |
2023-08-12 |
Not clear |
| Cristina Stasi, Massimo Rosselli, Anna Linda Zignego, Giacomo Laffi, Stefano Milan. Serotonin and its implication in the side-effects of interferon-based treatment of patients with chronic viral hepatitis: Pharmacological interventions. Hepatology research : the official journal of the Japan Society of Hepatology. vol 44. issue 1. 2014-01-06. PMID:23607322. |
therefore, this review will examine and discuss the putative role of serotonin and its metabolism in the development of depression during antiviral therapy, focusing on pharmacological interventions to reduce side-effects. |
2014-01-06 |
2023-08-12 |
Not clear |
| H Suzuki, R P A Barros, N Sugiyama, V Krishnan, B C Yaden, H-J Kim, M Warner, J-Å Gustafsso. Involvement of estrogen receptor β in maintenance of serotonergic neurons of the dorsal raphe. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:22665260. |
serotonin synthesis, release and reuptake in the dr are targets of pharmaceuticals in the treatment of depression. |
2014-01-03 |
2023-08-12 |
mouse |
| Tsuyoshi Nogami, Harumasa Takano, Ryosuke Arakawa, Tetsuya Ichimiya, Hironobu Fujiwara, Yasuyuki Kimura, Fumitoshi Kodaka, Takeshi Sasaki, Keisuke Takahata, Masayuki Suzuki, Tomohisa Nagashima, Takaaki Mori, Hitoshi Shimada, Hajime Fukuda, Mizuho Sekine, Amane Tateno, Hidehiko Takahashi, Hiroshi Ito, Yoshiro Okubo, Tetsuya Suhar. Occupancy of serotonin and norepinephrine transporter by milnacipran in patients with major depressive disorder: a positron emission tomography study with [(11)C]DASB and (S,S)-[(18)F]FMeNER-D(2). The international journal of neuropsychopharmacology. vol 16. issue 5. 2014-01-03. PMID:23067569. |
antidepressants used for treatment of depression exert their efficacy by blocking reuptake at serotonin transporters (5-htt) and/or norepinephrine transporters (net). |
2014-01-03 |
2023-08-12 |
Not clear |
| C B P Martin, F Ramond, D T Farrington, A S Aguiar, C Chevarin, A-S Berthiau, S Caussanel, L Lanfumey, K Herrick-Davis, M Hamon, J J Madjar, R Mongea. RNA splicing and editing modulation of 5-HT(2C) receptor function: relevance to anxiety and aggression in VGV mice. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:23247076. |
changes in serotonin(2c) receptor (5-htr2c) editing, splicing and density were found in conditions such as depression and suicide, but mechanisms explaining the changes in 5-htr2c function are unknown. |
2014-01-03 |
2023-08-12 |
mouse |
| Yi Liu, Yong-Hua Zhang, Man Jin, Wen-Juan Li. [Study on clinical effect enhancement of acupuncture for depression with chronic pain treated with SSRI antidepressants]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 33. issue 8. 2014-01-02. PMID:24195207. |
to compare the difference in the clinical efficacy on depression with chronic pain between the simple medication of selective serotonin uptake inhibition antidepressants (ssris) and the combined therapy of acupuncture and ssris. |
2014-01-02 |
2023-08-12 |
Not clear |
| Pei-Shen Ho, Kellen Kai-Jen Ho, Wen-Sheng Huang, Che-Hung Yen, Mei-Chen Shih, Lie-Hang Shen, Kuo-Hsing Ma, San-Yuan Huan. Association study of serotonin transporter availability and SLC6A4 gene polymorphisms in patients with major depression. Psychiatry research. vol 212. issue 3. 2013-12-30. PMID:23149035. |
association study of serotonin transporter availability and slc6a4 gene polymorphisms in patients with major depression. |
2013-12-30 |
2023-08-12 |
Not clear |
| Pei-Shen Ho, Kellen Kai-Jen Ho, Wen-Sheng Huang, Che-Hung Yen, Mei-Chen Shih, Lie-Hang Shen, Kuo-Hsing Ma, San-Yuan Huan. Association study of serotonin transporter availability and SLC6A4 gene polymorphisms in patients with major depression. Psychiatry research. vol 212. issue 3. 2013-12-30. PMID:23149035. |
the serotonin transporter (sert) is hypothesized to be an important component of the pathophysiology of major depression (md). |
2013-12-30 |
2023-08-12 |
Not clear |
| Michelle D Failla, Josh N Burkhardt, Megan A Miller, Joelle M Scanlon, Yvette P Conley, Robert E Ferrell, Amy K Wagne. Variants of SLC6A4 in depression risk following severe TBI. Brain injury. vol 27. issue 6. 2013-12-30. PMID:23672445. |
while the role of serotonin in the pathology and treatment of idiopathic major depression may be somewhat controversial, it is unclear what role serotonin may play in ptd following a tbi. |
2013-12-30 |
2023-08-12 |
Not clear |
| Dan J Stein, Francoise Picarel-Blanchot, Sidney H Kenned. Efficacy of the novel antidepressant agomelatine for anxiety symptoms in major depression. Human psychopharmacology. vol 28. issue 2. 2013-12-27. PMID:23532747. |
the antidepressant, agomelatine, which acts as an agonist at melatonin mt(1) and mt(2) receptors and as an antagonist at serotonin 5-ht(2c) receptors, has demonstrated efficacy and safety in both major depression and generalized anxiety disorder. |
2013-12-27 |
2023-08-12 |
Not clear |
| Chittaranjan Andrade, Chethan B Kumar, Sandarsh Sury. Cardiovascular mechanisms of SSRI drugs and their benefits and risks in ischemic heart disease and heart failure. International clinical psychopharmacology. vol 28. issue 3. 2013-12-23. PMID:23325305. |
selective serotonin reuptake inhibitors (ssris) are commonly used to treat depression. |
2013-12-23 |
2023-08-12 |
Not clear |
| Dustin W Wooten, Ansel T Hillmer, Jeffrey M Moirano, Dana L Tudorascu, Elizabeth O Ahlers, Maxim S Slesarev, Todd E Barnhart, Jogeshwar Mukherjee, Mary L Schneider, Bradley T Christia. 5-HT1A sex based differences in Bmax, in vivo KD, and BPND in the nonhuman primate. NeuroImage. vol 77. 2013-12-23. PMID:23537936. |
serotonin (5-ht) dysfunction has been implicated in neuropsychiatric illnesses and may play a pivotal role in the differential prevalence of depression between the sexes. |
2013-12-23 |
2023-08-12 |
monkey |
| John V Lavigne, Laura B K Herzing, Edwin H Cook, Susan A Lebailly, Karen R Gouze, Joyce Hopkins, Fred B Bryan. Gene × environment effects of serotonin transporter, dopamine receptor D4, and monoamine oxidase A genes with contextual and parenting risk factors on symptoms of oppositional defiant disorder, anxiety, and depression in a community sample of 4-year-old children. Development and psychopathology. vol 25. issue 2. 2013-12-17. PMID:23627963. |
gene × environment effects of serotonin transporter, dopamine receptor d4, and monoamine oxidase a genes with contextual and parenting risk factors on symptoms of oppositional defiant disorder, anxiety, and depression in a community sample of 4-year-old children. |
2013-12-17 |
2023-08-12 |
Not clear |
| John V Lavigne, Laura B K Herzing, Edwin H Cook, Susan A Lebailly, Karen R Gouze, Joyce Hopkins, Fred B Bryan. Gene × environment effects of serotonin transporter, dopamine receptor D4, and monoamine oxidase A genes with contextual and parenting risk factors on symptoms of oppositional defiant disorder, anxiety, and depression in a community sample of 4-year-old children. Development and psychopathology. vol 25. issue 2. 2013-12-17. PMID:23627963. |
in comparison with the short forms (s/s, s/l) of the serotonin transporter linked polymorphic repeat, the long form (l/l) was associated with greater increases in symptoms of oppositional defiant disorder in interaction with family stress and with greater increases in symptoms of child depression and anxiety in interaction with caretaker depression, family conflict, and socioeconomic status. |
2013-12-17 |
2023-08-12 |
Not clear |
| b' Rune Jonassen, Kari B Foss Haug, Tor Endestad, H\\xc3\\xa5vard Bentsen, Runa M Grimholt, Nils I Landr\\xc3\\xb. Associations between serotonin transporter polymorphisms and cognitive processing applying the Emo 1-back task. Cognition & emotion. vol 27. issue 3. 2013-12-16. PMID:23017007.' |
down regulation of serotonin transporter (5-htt) expression has been associated with brain function and major depression. |
2013-12-16 |
2023-08-12 |
human |
| J J Cutuli, K Lee Raby, Dante Cicchetti, Michelle M Englund, Byron Egelan. Contributions of maltreatment and serotonin transporter genotype to depression in childhood, adolescence, and early adulthood. Journal of affective disorders. vol 149. issue 1-3. 2013-12-12. PMID:22951355. |
contributions of maltreatment and serotonin transporter genotype to depression in childhood, adolescence, and early adulthood. |
2013-12-12 |
2023-08-12 |
Not clear |
| Jose A Franco-Chaves, Camilo F Mateus, David A Luckenbaugh, Pedro E Martinez, Alan G Mallinger, Carlos A Zarat. Combining a dopamine agonist and selective serotonin reuptake inhibitor for the treatment of depression: a double-blind, randomized pilot study. Journal of affective disorders. vol 149. issue 1-3. 2013-12-12. PMID:23517885. |
combining a dopamine agonist and selective serotonin reuptake inhibitor for the treatment of depression: a double-blind, randomized pilot study. |
2013-12-12 |
2023-08-12 |
Not clear |