| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Donatella Marazziti, Paola Landi, Stefano Baroni, Federica Vanelli, Natalia Bartolommei, Michela Picchetti, Liliana Dell'Oss. The role of platelet/lymphocyte serotonin transporter in depression and beyond. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23514378. |
a large amount of the data gathered in the last 50 years support the hypothesis that alterations of the serotonin (5-ht) neurotransmission play a crucial role in the pathophysiology of not only major depression (md), but also of different neuropsychiatric disorders. |
2013-10-29 |
2023-08-12 |
Not clear |
| Donatella Marazziti, Paola Landi, Stefano Baroni, Federica Vanelli, Natalia Bartolommei, Michela Picchetti, Liliana Dell'Oss. The role of platelet/lymphocyte serotonin transporter in depression and beyond. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23514378. |
this paper aims to review briefly the literature on the 5-ht hypothesis of depression with a major focus on the possible role of sert in this disorder, while highlighting how recent data are more oriented on dimensional rather than nosological involvement of this structure in different conditions spanning from normality to pathology. |
2013-10-29 |
2023-08-12 |
Not clear |
| Gregory Oxenkru. Serotonin-kynurenine hypothesis of depression: historical overview and recent developments. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23514379. |
the cause of serotonin deficiency in depression was attributed to the shunt of trp "metabolism away from serotonin production towards kyn production" due to cortisol-induced activation of liver enzyme, tryptophan 2,3- dioxygenase, the rate-limiting enzyme of trp - kyn pathway. |
2013-10-29 |
2023-08-12 |
Not clear |
| Mario Catena-Dell'Osso, Francesco Rotella, Adriana Dell'Osso, Andrea Fagiolini, Donatella Marazzit. Inflammation, serotonin and major depression. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23531160. |
inflammation, serotonin and major depression. |
2013-10-29 |
2023-08-12 |
Not clear |
| Donatella Marazzit. Depression and serotonin: a never ending story. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23547753. |
depression and serotonin: a never ending story. |
2013-10-29 |
2023-08-12 |
Not clear |
| Chiara Fabbri, Agnese Marsano, Alessandro Serrett. Genetics of serotonin receptors and depression: state of the art. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23547754. |
genetics of serotonin receptors and depression: state of the art. |
2013-10-29 |
2023-08-12 |
Not clear |
| Naozumi Araragi, Klaus-Peter Lesc. Serotonin (5-HT) in the regulation of depression-related emotionality: insight from 5-HT transporter and tryptophan hydroxylase-2 knockout mouse models. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23547810. |
over the last decade, research on mice with a targeted inactivation of the 5-ht transporter (5-htt, sert, slc6a4) has considerably advanced our knowledge about functions that the 5-htt plays in the context of emotion related to depression. |
2013-10-29 |
2023-08-12 |
mouse |
| Mitra Safa, Saeed Fallah Tafti, Fatemeh Ghassem Boroujerdi, Firouzeh Talisch. Clinical trial in the treatment of 80 Iranian patients with major depression disorder by the combination of omega 3 fatty acid and a selective serotonin reuptake inhibitor. Therapeutic advances in psychopharmacology. vol 3. issue 4. 2013-10-29. PMID:24167691. |
clinical trial in the treatment of 80 iranian patients with major depression disorder by the combination of omega 3 fatty acid and a selective serotonin reuptake inhibitor. |
2013-10-29 |
2023-08-12 |
Not clear |
| Susan K Wood, Xiao-Yan Zhang, Beverly A S Reyes, Catherine S Lee, Elisabeth J Van Bockstaele, Rita J Valentin. Cellular adaptations of dorsal raphe serotonin neurons associated with the development of active coping in response to social stress. Biological psychiatry. vol 73. issue 11. 2013-10-28. PMID:23452664. |
stress and depression are linked in part through regulation of the dorsal raphe (dr)-serotonin (5-ht) system by the stress-related neuropeptide, corticotropin-releasing factor (crf). |
2013-10-28 |
2023-08-12 |
rat |
| Angela Amancio-Dos-Santos, Luciana Maria Silva de Seixas Maia, Paula Catirina Pereira da Silva Germano, Yleana Danielle Dos Santos Negrão, Rubem Carlos Araújo Guede. Tianeptine facilitates spreading depression in well-nourished and early-malnourished adult rats. European journal of pharmacology. vol 706. issue 1-3. 2013-10-28. PMID:23499681. |
here we used cortical spreading depression (csd) in the rat as a neurophysiological parameter to investigate the interaction between nutritional status and treatment with tianeptine, a serotonin uptake enhancer. |
2013-10-28 |
2023-08-12 |
rat |
| C Rob Marku. Interaction between the 5-HTTLPR genotype, impact of stressful life events, and trait neuroticism on depressive symptoms in healthy volunteers. Psychiatric genetics. vol 23. issue 3. 2013-10-23. PMID:23492930. |
recent biopsychological research on stress-related psychopathology shows promising evidence for the 5-hydroxytryptamine (5-ht) transporter linked polymorphic region (5-httlpr) genotype by life event interaction on depression. |
2013-10-23 |
2023-08-12 |
human |
| Kevin M Wood, Parastoo Hashem. Fast-scan cyclic voltammetry analysis of dynamic serotonin reponses to acute escitalopram. ACS chemical neuroscience. vol 4. issue 5. 2013-10-22. PMID:23597074. |
the treatment of depression with selective serotonin reuptake inhibitors, ssris, is important to study on a neurochemical level because of the therapeutic variability experienced by many depressed patients. |
2013-10-22 |
2023-08-12 |
mouse |
| Maki Egami, Yoshiomi Imamura, Hiromi Nabeta, Yoshito Mizoguchi, Shigeto Yamad. Saliva levels of 3-methoxy-4-hydroxyphenylglycol and clinical efficacy of mirtazapine or selective serotonin reuptake inhibitors in patients with major depression. Human psychopharmacology. vol 28. issue 1. 2013-10-21. PMID:23124792. |
saliva levels of 3-methoxy-4-hydroxyphenylglycol and clinical efficacy of mirtazapine or selective serotonin reuptake inhibitors in patients with major depression. |
2013-10-21 |
2023-08-12 |
Not clear |
| R Bravo, S Matito, J Cubero, S D Paredes, L Franco, M Rivero, A B Rodríguez, C Barrig. Tryptophan-enriched cereal intake improves nocturnal sleep, melatonin, serotonin, and total antioxidant capacity levels and mood in elderly humans. Age (Dordrecht, Netherlands). vol 35. issue 4. 2013-10-17. PMID:22622709. |
our aim was to analyze whether the consumption of cereals enriched with tryptophan, the precursor of both serotonin and melatonin, may help in the reconsolidation of the sleep/wake cycle and counteract depression and anxiety in 35 middle-aged/elderly (aged 55-75 year) volunteers in a simple blind assay. |
2013-10-17 |
2023-08-12 |
human |
| Steven L Dubovsk. Pharmacokinetic evaluation of olanzapine + fluoxetine for the treatment of bipolar depression. Expert opinion on drug metabolism & toxicology. vol 9. issue 2. 2013-10-17. PMID:23294052. |
a proprietary combination of the atypical antipsychotic drug olanzapine and the serotonin reuptake inhibitor fluoxetine (ofc, symbyax) was approved for the treatment of bipolar depression based on a double-blind, placebo-controlled comparison of olanzapine, ofc, and placebo. |
2013-10-17 |
2023-08-12 |
Not clear |
| W J Xu, Y Zhao, F Q Huo, J Q Du, J S Tan. Involvement of ventrolateral orbital cortex 5-HT 1-7 receptors in 5-HT induced depression of spared nerve injury allodynia. Neuroscience. vol 238. 2013-10-17. PMID:23485814. |
involvement of ventrolateral orbital cortex 5-ht 1-7 receptors in 5-ht induced depression of spared nerve injury allodynia. |
2013-10-17 |
2023-08-12 |
rat |
| W J Xu, Y Zhao, F Q Huo, J Q Du, J S Tan. Involvement of ventrolateral orbital cortex 5-HT 1-7 receptors in 5-HT induced depression of spared nerve injury allodynia. Neuroscience. vol 238. 2013-10-17. PMID:23485814. |
these results suggest that although 5-ht1-7 receptor subtypes in the vlo do not have a tonic modulatory action on the allodynia induced by sni, they are involved in mediating the depression of the sni allodynia produced by injection of 5ht into vlo. |
2013-10-17 |
2023-08-12 |
rat |
| Whitney M Weikum, Ursula Brain, Cecil M Y Chau, Ruth E Grunau, W Thomas Boyce, Adele Diamond, Tim F Oberlande. Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age. Frontiers in cellular neuroscience. vol 7. 2013-10-16. PMID:24130516. |
prenatal exposure to serotonin reuptake inhibitor (sri) antidepressants and maternal depression may affect prefrontal cognitive skills (executive functions; efs) including self-control, working memory and cognitive flexibility. |
2013-10-16 |
2023-08-12 |
Not clear |
| Shima Sahraian, Mohammad Babashams, Pouria Reza-Soltani, Hossein Najmabadi, Kimia Kahrizi, Sahel Hemmati Gorgan. Serotonin Transporter Polymorphism (5-HTTLPR) and Citalopram Effectiveness in Iranian Patients with Major Depressive Disorder. Iranian journal of psychiatry. vol 8. issue 2. 2013-10-16. PMID:24130607. |
several studies have implicated the 5-httlpr polymorphism in treatment outcomes of selective serotonin re-uptake inhibitors in patients with major depression. |
2013-10-16 |
2023-08-12 |
Not clear |
| Wen-Hui Wu, R L Coope. Physiological separation of vesicle pools in low- and high-output nerve terminals. Neuroscience research. vol 75. issue 4. 2013-09-30. PMID:23396244. |
the working model is that upon depression of the tonic terminal, serotonin (5-ht) has a large rp to act on in order to recruit vesicles to the rrp; whereas, the phasic terminal, 5-ht can recruit rp vesicles to the rrp prior to synaptic depression but not after depression. |
2013-09-30 |
2023-08-12 |
Not clear |