| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yang Li, Jing Liu, Xu Liu, Cun-Jin Su, Qi-Lin Zhang, Zhi-Hong Wang, Lei-Fang Cao, Xue-Yan Guo, Ya Huang, Weifeng Luo, Tong Li. Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain. Neuroscience bulletin. vol 35. issue 4. 2020-02-18. PMID:30900142. |
collectively, these results demonstrated that bont/a treatment has anti-depressant-like activity in mice, and this is associated with increased 5-ht levels and the activation of bdnf/erk/creb pathways in the hippocampus, supporting further investigation of bont/a therapy in depression. |
2020-02-18 |
2023-08-13 |
mouse |
| Shaojiong Zhou, Shuo Liu, Xiaoqiang Liu, Weiduan Zhuan. Selective serotonin reuptake inhibitors for functional independence and depression prevention in early stage of post-stroke: A meta-analysis. Medicine. vol 99. issue 6. 2020-02-17. PMID:32028426. |
selective serotonin reuptake inhibitors for functional independence and depression prevention in early stage of post-stroke: a meta-analysis. |
2020-02-17 |
2023-08-13 |
Not clear |
| Shaojiong Zhou, Shuo Liu, Xiaoqiang Liu, Weiduan Zhuan. Selective serotonin reuptake inhibitors for functional independence and depression prevention in early stage of post-stroke: A meta-analysis. Medicine. vol 99. issue 6. 2020-02-17. PMID:32028426. |
the efficacy and safety of selective serotonin reuptake inhibitors (ssris) for functional independence and depression prevention in early stage of post-stroke (within 1 month after stroke onset) are still unclear. |
2020-02-17 |
2023-08-13 |
Not clear |
| Chi-Wei Lee, Yi-Ju Chen, Han-Fang Wu, Yueh-Jung Chung, Yi-Chao Lee, Cheng-Ta Li, Hui-Ching Li. Ketamine ameliorates severe traumatic event-induced antidepressant-resistant depression in a rat model through ERK activation. Progress in neuro-psychopharmacology & biological psychiatry. vol 93. 2020-02-14. PMID:30940482. |
the present study focused on selective serotonin reuptake inhibitor (ssri) resistance, and aimed to investigate whether higher levels of traumatic stress caused by greater numbers of foot-shocks may lead to severe depression and to examine the feasibility of this as an animal model of ssri-resistant depression. |
2020-02-14 |
2023-08-13 |
rat |
| Elham Sharafi, Arsia Taghva, Mohammad Arbabi, Afsaneh Dadarkhah, Jamshid Ghader. Transcranial Direct Current Stimulation for Treatment-Resistant Major Depression: A Double-Blind Randomized Sham-Controlled Trial. Clinical EEG and neuroscience. vol 50. issue 6. 2020-02-14. PMID:31304775. |
individuals with less than 50% decrease in the intensity of depression after 8 weeks of treatment with selective serotonin reuptake inhibitors were recruited. |
2020-02-14 |
2023-08-13 |
Not clear |
| Aniruddha Basu, R K Chadda, Mamta Sood, Harpreet Kaur, Ritushree Kukret. A preliminary association study between serotonin transporter (5-HTTLPR), receptor polymorphisms (5-HTR1A, 5-HTR2A) and depression symptom-clusters in a north Indian population suffering from Major Depressive Disorder (MDD). Asian journal of psychiatry. vol 43. 2020-02-11. PMID:31228794. |
a preliminary association study between serotonin transporter (5-httlpr), receptor polymorphisms (5-htr1a, 5-htr2a) and depression symptom-clusters in a north indian population suffering from major depressive disorder (mdd). |
2020-02-11 |
2023-08-13 |
Not clear |
| Gary Tin, Tarek Mohamed, Arash Shakeri, Amy Trinh Pham, Praveen P N Ra. Interactions of Selective Serotonin Reuptake Inhibitors with β-Amyloid. ACS chemical neuroscience. vol 10. issue 1. 2020-02-06. PMID:30157623. |
selective serotonin reuptake inhibitors (ssris) are a known class of united states food and drug administration approved drugs used in the treatment of depression. |
2020-02-06 |
2023-08-13 |
Not clear |
| Jennifer Kott, Susanne Brummelt. Trick or treat? Evaluating contributing factors and sex-differences for developmental effects of maternal depression and its treatment. Hormones and behavior. vol 111. 2020-02-03. PMID:30658054. |
maternal depression and treatment with selective serotonin reuptake inhibitors (ssris), the most common form of pharmaceutical intervention, can both have an impact on infant development. |
2020-02-03 |
2023-08-13 |
human |
| Aruna Sharma, Rudy J Castellani, Mark A Smith, Dafin Fior Muresanu, Prasanta Kumar Dey, Hari Shanker Sharm. 5-Hydroxytryptophan: A precursor of serotonin influences regional blood-brain barrier breakdown, cerebral blood flow, brain edema formation, and neuropathology. International review of neurobiology. vol 146. 2020-02-03. PMID:31349924. |
5-hydroxytryptophan (5-htp), a precursor of serotonin, is therapeutically used for several psychiatric disorders such as anxiety and depression in the clinic. |
2020-02-03 |
2023-08-13 |
rat |
| Naama Rotem-Kohavi, Lynne J Williams, Angela M Muller, Hervé Abdi, Naznin Virji-Babul, Bruce H Bjornson, Ursula Brain, Janet F Werker, Ruth E Grunau, Steven P Miller, Tim F Oberlande. Hub distribution of the brain functional networks of newborns prenatally exposed to maternal depression and SSRI antidepressants. Depression and anxiety. vol 36. issue 8. 2020-01-31. PMID:31066992. |
prenatal maternal depression (pmd) and selective serotonin reuptake inhibitor (ssri) antidepressants are associated with increased developmental risk in infants. |
2020-01-31 |
2023-08-13 |
Not clear |
| Ana Gheorghe, Wansu Qiu, Liisa A M Gale. Hormonal Regulation of Hippocampal Neurogenesis: Implications for Depression and Exercise. Current topics in behavioral neurosciences. vol 43. 2020-01-28. PMID:30414016. |
we examine the possible role of neurogenesis in the etiology of depression and influencing treatment by examining the influence of both pharmacological (selective serotonin reuptake inhibitors, tricyclic antidepressants) treatments and non-pharmacological (exercise) remedies. |
2020-01-28 |
2023-08-13 |
Not clear |
| Muhammad Adnan Bashir, Arif-Ullah Khan, Haroon Badshah, Edson Rodrigues-Filho, Zia Ud Din, Aslam Kha. Synthesis, characterization, molecular docking evaluation, antidepressant, and anti-Alzheimer effects of dibenzylidene ketone derivatives. Drug development research. vol 80. issue 5. 2020-01-27. PMID:30964563. |
both a1k1 and a2k2 showed high binding affinities against various proteins involved in depression and alzheimer's mechanisms like monoamine oxidase b, acetylcholinesterase, norepinephrine transporter 2, serotonin transporter, dopamine receptor, serotonin receptor modulator, and beta-amyloid targets. |
2020-01-27 |
2023-08-13 |
mouse |
| Faruk Ugu. Short-Term Safety of Paroxetine Plus Low-Dose Mirtazapine During Lactation. Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine. vol 14. issue 2. 2020-01-15. PMID:30489153. |
selective serotonin reuptake inhibitors (ssris), especially sertraline and paroxetine, are first-line antidepressants in the treatment of postpartum depression in breastfeeding women as these drugs are well tolerated by most breastfed infants. |
2020-01-15 |
2023-08-13 |
Not clear |
| Meiyan Liu, Jianyang Liu, Lijun Zhang, Qingshan Geng, Yingbin G. Antidepressant-like effects of ginseng fruit saponin in myocardial infarction mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 115. 2020-01-14. PMID:31054510. |
recently, the development of cardiovascular disease (cvd) has been proved to be closely associated with depression in which 5-ht plays a crucial role. |
2020-01-14 |
2023-08-13 |
mouse |
| Andrée-Anne Hudon Thibeault, Yossef López de Los Santos, Nicolas Doucet, J Thomas Sanderson, Cathy Vaillancour. Serotonin and serotonin reuptake inhibitors alter placental aromatase. The Journal of steroid biochemistry and molecular biology. vol 195. 2020-01-14. PMID:31509772. |
serotonin reuptake inhibitors (sris) are currently the main molecules prescribed to pregnant women that suffer from depression. |
2020-01-14 |
2023-08-13 |
Not clear |
| Naama Rotem-Kohavi, Lynne J Williams, Naznin Virji-Babul, Bruce H Bjornson, Ursula Brain, Janet F Werker, Ruth E Grunau, Steven P Miller, Tim F Oberlande. Alterations in Resting-State Networks Following In Utero Selective Serotonin Reuptake Inhibitor Exposure in the Neonatal Brain. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 4. issue 1. 2020-01-06. PMID:30292808. |
selective serotonin reuptake inhibitors (ssris) are commonly used to treat depression during pregnancy. |
2020-01-06 |
2023-08-13 |
Not clear |
| N A Trusova, O S Levi. [Clinical significance and possibilities of therapy of post-stroke depression]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 119. issue 9. Vyp. 2. 2020-01-03. PMID:31825392. |
the action of antidepressants, in particular selective serotonin reuptake inhibitors (ssris), can be directed to the main pathophysiological processes of post-stroke depression. |
2020-01-03 |
2023-08-13 |
Not clear |
| Susannah E Murphy, Catherine J Harme. Tracking the Brain: White Matter Structure Is Associated With Selective Serotonin Reuptake Inhibitor Treatment Response in Depression. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 4. issue 10. 2019-12-30. PMID:31590723. |
tracking the brain: white matter structure is associated with selective serotonin reuptake inhibitor treatment response in depression. |
2019-12-30 |
2023-08-13 |
Not clear |
| Hadeer Emam, David C Steffens, Godfrey D Pearlson, Lihong Wan. Increased ventromedial prefrontal cortex activity and connectivity predict poor sertraline treatment outcome in late-life depression. International journal of geriatric psychiatry. vol 34. issue 5. 2019-12-20. PMID:30761621. |
previous studies of imaging predictors on acute treatment response in late-life depression (lld) demonstrated that poor response to selective serotonin reuptake inhibitors (ssris) is associated with pre-treatment low functional connectivity (fc) within executive control network and high fc within default-mode network including the ventromedial prefrontal cortex (vmpfc). |
2019-12-20 |
2023-08-13 |
Not clear |
| YongHwan Kim, Young Sook Lee, Myeong Gyu Kim, Yun-Kyoung Song, Youngwon Kim, Hayoung Jang, Jae Hyun Kim, Nayoung Han, Eunhee Ji, In-Wha Kim, Jung Mi O. The effect of selective serotonin reuptake inhibitors on major adverse cardiovascular events: a meta-analysis of randomized-controlled studies in depression. International clinical psychopharmacology. vol 34. issue 1. 2019-12-19. PMID:30096056. |
the effect of selective serotonin reuptake inhibitors on major adverse cardiovascular events: a meta-analysis of randomized-controlled studies in depression. |
2019-12-19 |
2023-08-13 |
Not clear |