| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miriam A Schiele, Leonie Kollert, Klaus-Peter Lesch, Volker Arolt, Peter Zwanzger, Jürgen Deckert, Christiane Ziegler, Katharina Domschk. Hypermethylation of the serotonin transporter gene promoter in panic disorder-Epigenetic imprint of comorbid depression? European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 10. 2020-07-14. PMID:31353282. |
hypermethylation of the serotonin transporter gene promoter in panic disorder-epigenetic imprint of comorbid depression? |
2020-07-14 |
2023-08-13 |
Not clear |
| Hélène Party, Cléo Dujarrier, Marie Hébert, Sophie Lenoir, Sara Martinez de Lizarrondo, Raphaël Delépée, Claudine Fauchon, Marie-Christine Bouton, Pauline Obiang, Olivier Godefroy, Etienne Save, Laurent Lecardeur, Joëlle Chabry, Denis Vivien, Véronique Agi. Plasminogen Activator Inhibitor-1 (PAI-1) deficiency predisposes to depression and resistance to treatments. Acta neuropathologica communications. vol 7. issue 1. 2020-07-13. PMID:31610810. |
we demonstrate here that pai-1 plays a key role in depression by a mechanism independent of the tissue-type plasminogen activator (tpa) - brain-derived neurotrophic factor (bdnf) axis, but associated with impaired metabolisms of serotonin and dopamine. |
2020-07-13 |
2023-08-13 |
mouse |
| Zsombor Szoke-Kovacs, Csaba More, Rita Szoke-Kovacs, Endre Mathe, Ede Frecsk. Selective Inhibition of the Serotonin Transporter in the Treatment of Depression: Sertraline, Fluoxetine and Citalopram. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 22. issue 1. 2020-07-09. PMID:32329748. |
selective inhibition of the serotonin transporter in the treatment of depression: sertraline, fluoxetine and citalopram. |
2020-07-09 |
2023-08-13 |
human |
| Giuseppe Caruso, Claudia G Fresta, Margherita Grasso, Rosa Santangelo, Giuseppe Lazzarino, Susan M Lunte, Filippo Carac. Inflammation as the Common Biological Link Between Depression and Cardiovascular Diseases: Can Carnosine Exert a Protective Role? Current medicinal chemistry. vol 27. issue 11. 2020-07-08. PMID:31296155. |
pro-inflammatory cytokines interfere with many of the pathophysiological mechanisms relevant to depression by upregulating the rate-limiting enzymes in the metabolic pathway of tryptophan and altering serotonin metabolism. |
2020-07-08 |
2023-08-13 |
Not clear |
| Manesh Gopaldas, Francesca Zanderigo, Serena Zhan, R Todd Ogden, Jeffrey M Miller, Harry Rubin-Falcone, Thomas B Cooper, Maria A Oquendo, Gregory Sullivan, J John Mann, M Elizabeth Sublett. Brain serotonin transporter binding, plasma arachidonic acid and depression severity: A positron emission tomography study of major depression. Journal of affective disorders. vol 257. 2020-07-07. PMID:31319341. |
brain serotonin transporter binding, plasma arachidonic acid and depression severity: a positron emission tomography study of major depression. |
2020-07-07 |
2023-08-13 |
Not clear |
| Hatice Aygu. The effect of fluoxetine on penicillin-induced epileptiform activity. Epilepsy & behavior : E&B. vol 95. 2020-07-06. PMID:31026788. |
fluoxetine is the most widely used selective serotonin reuptake inhibitor (ssri) in depression. |
2020-07-06 |
2023-08-13 |
Not clear |
| Daniel Worms, Barbara Maertens, Jan Kubicek, Udaya Kumar Tiruttani Subhramanyam, Jörg Labah. Expression, purification and stabilization of human serotonin transporter from E. coli. Protein expression and purification. vol 164. 2020-07-06. PMID:31442583. |
the serotonin transporter belongs to the family of sodium-chloride coupled neurotransmitter transporter and is related to depression in humans. |
2020-07-06 |
2023-08-13 |
human |
| Xue Zhang, Scott A Huettel, O'Dhaniel A Mullette-Gillman, Hua Guo, Lihong Wan. Exploring common changes after acute mental stress and acute tryptophan depletion: Resting-state fMRI studies. Journal of psychiatric research. vol 113. 2020-07-01. PMID:30959228. |
stress and low serotonin levels are important biological factors in depression and anxiety etiologies. |
2020-07-01 |
2023-08-13 |
Not clear |
| Emily Durham, Yuhua Zhang, Amanda LaRue, Amy Bradshaw, James Cra. Selective serotonin reuptake inhibitors (SSRI) affect murine bone lineage cells. Life sciences. vol 255. 2020-06-29. PMID:32450170. |
data suggest pharmacological treatment of depression with selective serotonin reuptake inhibitors (ssri) may impair bone health. |
2020-06-29 |
2023-08-13 |
Not clear |
| Louisa J. Steinberg, Mark D. Underwood, Mihran J. Bakalian, Suham A. Kassir, J. John Mann, Victoria Arang. 5-HT1A receptor, 5-HT2A receptor and serotonin transporter binding in the human auditory cortex in depression Journal of psychiatry & neuroscience : JPN. vol 44. issue 5. 2020-06-22. PMID:31120232. |
5-ht1a receptor, 5-ht2a receptor and serotonin transporter binding in the human auditory cortex in depression serotonergic system abnormalities are implicated in many psychiatric disorders, including major depression. |
2020-06-22 |
2023-08-13 |
human |
| Won-Jun Jang, Sung Keun Jung, Tam Thuy Lu Vo, Chul-Ho Jeon. Anticancer activity of paroxetine in human colon cancer cells: Involvement of MET and ERBB3. Journal of cellular and molecular medicine. vol 23. issue 2. 2020-06-17. PMID:30421568. |
paroxetine, one of the selective serotonin reuptake inhibitors (ssris), has been widely prescribed for the treatment of depression and anxiety disorders. |
2020-06-17 |
2023-08-13 |
mouse |
| Anna Sophie Thue Hvilsom, Thea P Lillethorup, Peter Iversen, Doris J Doudet, Gregers Wegener, Anne M Landa. Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 4. 2020-06-17. PMID:30826156. |
cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli. |
2020-06-17 |
2023-08-13 |
rat |
| Anna Sophie Thue Hvilsom, Thea P Lillethorup, Peter Iversen, Doris J Doudet, Gregers Wegener, Anne M Landa. Cortical and striatal serotonin transporter binding in a genetic rat model of depression and in response to electroconvulsive stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 29. issue 4. 2020-06-17. PMID:30826156. |
the serotonergic system plays an important role in depression and alterations in the serotonin transporter (sert) are seen both in depression and response to antidepressant pharmacotherapies. |
2020-06-17 |
2023-08-13 |
rat |
| Juliane Zemdegs, Hugo Martin, Hiranya Pintana, Sebastien Bullich, Stella Manta, Marie A Marqués, Cédric Moro, Sophie Layé, Fabien Ducrocq, Nipon Chattipakorn, Siriporn C Chattipakorn, Claire Rampon, Luc Pénicaud, Xavier Fioramonti, Bruno P Guiar. Metformin Promotes Anxiolytic and Antidepressant-Like Responses in Insulin-Resistant Mice by Decreasing Circulating Branched-Chain Amino Acids. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 30. 2020-06-17. PMID:31160539. |
our results indicated that hfd-fed mice displayed impairment in the electrical activity of dorsal raphe 5-ht neurons, attenuated hippocampal extracellular 5-ht concentrations and anxiety, one of the most visible and early symptoms of depression. |
2020-06-17 |
2023-08-13 |
mouse |
| Susann Matthes, Valentina Mosienko, Elena Popova, Marion Rivalan, Michael Bader, Natalia Alenin. Targeted Manipulation of Brain Serotonin: RNAi-Mediated Knockdown of Tryptophan Hydroxylase 2 in Rats. ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:30977636. |
neuronal 5-ht is a key regulator of mood and behavior and its deficiency has been implicated in a variety of neuropsychiatric disorders, e.g., depression and anxiety. |
2020-06-11 |
2023-08-13 |
rat |
| Jens H van Dalfsen, C Rob Marku. The involvement of sleep in the relationship between the serotonin transporter gene-linked polymorphic region (5-HTTLPR) and depression: A systematic review. Journal of affective disorders. vol 256. 2020-06-11. PMID:31181376. |
the involvement of sleep in the relationship between the serotonin transporter gene-linked polymorphic region (5-httlpr) and depression: a systematic review. |
2020-06-11 |
2023-08-13 |
Not clear |
| Xavier López-Gil, Laura Jiménez-Sánchez, Leticia Campa, Elena Castro, Clara Frago, Albert Adel. Role of Serotonin and Noradrenaline in the Rapid Antidepressant Action of Ketamine. ACS chemical neuroscience. vol 10. issue 7. 2020-06-11. PMID:31244055. |
there is data suggesting that deficits in serotonin neurotransmission can contribute to the development of depression. |
2020-06-11 |
2023-08-13 |
human |
| Dawid Gawliński, Irena Smaga, Magdalena Zaniewska, Kinga Gawlińska, Agata Faron-Górecka, Małgorzata Fili. Adaptive mechanisms following antidepressant drugs: Focus on serotonin 5-HT Pharmacological reports : PR. vol 71. issue 6. 2020-06-11. PMID:31546158. |
adaptive mechanisms following antidepressant drugs: focus on serotonin 5-ht there is a strong support for the role of serotonin (5-ht) neurotransmission in depression and in the mechanism of action of antidepressants. |
2020-06-11 |
2023-08-13 |
Not clear |
| Paul R. Albert, Brice Le François, Faranak Vahid-Ansar. Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigm Journal of psychiatry & neuroscience : JPN. vol 44. issue 3. 2020-06-09. PMID:30807072. |
genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-ht1a receptor gene as a paradigm major depression and anxiety are highly prevalent and involve chronic dysregulation of serotonin, but they remain poorly understood. |
2020-06-09 |
2023-08-13 |
human |
| P G Grieve, W P Fifer, N P Cousy, C E Monk, R I Stark, J A Gingrich, M M Myer. Neonatal infant EEG bursts are altered by prenatal maternal depression and serotonin selective reuptake inhibitor use. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 130. issue 11. 2020-06-08. PMID:31539768. |
neonatal infant eeg bursts are altered by prenatal maternal depression and serotonin selective reuptake inhibitor use. |
2020-06-08 |
2023-08-13 |
Not clear |