| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Edyta Możdżeń, Agnieszka Wąsik, Irena Romańska, Jerzy Michaluk, Lucyna Antkiewicz-Michalu. Antidepressant-like effect of 1,2,3,4-tetrahydroisoquinoline and its methyl derivative in animal models of depression. Pharmacological reports : PR. vol 69. issue 3. 2020-06-03. PMID:31994087. |
most of the currently used antidepressant drugs are monoamine-based compounds, acting by the inhibition of re-uptake or metabolism of noradrenaline (na) and/or serotonin (5-ht), because these neurotransmitters play a key role in the pathophysiology of depression. |
2020-06-03 |
2023-08-13 |
Not clear |
| Yea-Hyun Leem, Jee-Hun Jang, Jin-Sun Park, Hee-Sun Ki. Exercise exerts an anxiolytic effect against repeated restraint stress through 5-HT Psychoneuroendocrinology. vol 108. 2020-06-01. PMID:31248747. |
exercise exerts an anxiolytic effect against repeated restraint stress through 5-ht repeated or chronic stressful stimuli induce emotion- and mood-related abnormalities, such as anxiety and depression. |
2020-06-01 |
2023-08-13 |
mouse |
| Kevin J Cummings, Matthew R Hodge. The serotonergic system and the control of breathing during development. Respiratory physiology & neurobiology. vol 270. 2020-06-01. PMID:31362064. |
it was in these early years that some of the first demonstrations were made regarding a role for brain 5-ht in neurological function and behavior, including data implicating reduced brain levels of 5-ht in clinical depression. |
2020-06-01 |
2023-08-13 |
human |
| Koji Ohira, Hideo Hagihara, Miki Miwa, Katsuki Nakamura, Tsuyoshi Miyakaw. Fluoxetine-induced dematuration of hippocampal neurons and adult cortical neurogenesis in the common marmoset. Molecular brain. vol 12. issue 1. 2020-06-01. PMID:31383032. |
the selective serotonin reuptake inhibitor fluoxetine (flx) is widely used to treat depression and anxiety disorders. |
2020-06-01 |
2023-08-13 |
marmoset |
| Andre R Brunoni, Angel Carracedo, Olalla M Amigo, Ana L Pellicer, Leda Talib, Andre F Carvalho, Paulo A Lotufo, Isabela M Benseñor, Wagner Gattaz, Carolina Capp. Association of BDNF, HTR2A, TPH1, SLC6A4, and COMT polymorphisms with tDCS and escitalopram efficacy: ancillary analysis of a double-blind, placebo-controlled trial. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). vol 42. issue 2. 2020-05-26. PMID:31721892. |
we investigated whether single nucleotide polymorphisms (snps) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (bdnf, rs6265), the serotonin transporter (slc6a4, rs25531), the tryptophan hydroxylase 1 (tph1, rs1800532), the 5-hydroxytryptamine receptor 2a (htr2a, rs6311, rs6313, rs7997012), and the catechol-o-methyltransferase (comt, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tdcs) in major depression. |
2020-05-26 |
2023-08-13 |
Not clear |
| Chuan-Guo Guo, Ka Shing Cheung, Feifei Zhang, Esther W Chan, Lijia Chen, Ian C K Wong, Wai K Leun. Risks of hospitalization for upper gastrointestinal bleeding in users of selective serotonin reuptake inhibitors after Helicobacter pylori eradication therapy: a propensity score matching analysis. Alimentary pharmacology & therapeutics. vol 50. issue 9. 2020-05-25. PMID:31583734. |
selective serotonin reuptake inhibitors (ssris) are the first-line treatment for depression but there is a concern about the risk of upper gastrointestinal bleeding (ugib). |
2020-05-25 |
2023-08-13 |
Not clear |
| Coralie Berthoux, Alexander Barre, Joël Bockaert, Philippe Marin, Carine Bécame. Sustained Activation of Postsynaptic 5-HT2A Receptors Gates Plasticity at Prefrontal Cortex Synapses. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 4. 2020-05-22. PMID:29917056. |
here, we show that a 20-min exposure of mouse pfc slices to serotonin or the 5-ht2a receptor agonist 2,5-dimethoxy-4-iodoamphetamine (doi) produces a long-lasting depression of evoked ampa excitatory postsynaptic currents in layer v pyramidal neurons. |
2020-05-22 |
2023-08-13 |
mouse |
| Trevor W Robbin. Pharmacological treatment of cognitive deficits in nondementing mental health disorders
. Dialogues in clinical neuroscience. vol 21. issue 3. 2020-05-20. PMID:31749654. |
the possibility of treating cognitive deficits in depression via antidepressant medication (eg, selective serotonin reuptake inhibitors) and by adjunctive drug treatment has only recently received attention because of confounding, or possibly interactive, effects on mood. |
2020-05-20 |
2023-08-13 |
Not clear |
| Yi-Ting Lin, Tsui-Shan Lu, Richard A Hansen, Chi-Chuan Wan. Selective Serotonin Reuptake Inhibitor Use and Risk of Arrhythmia: A Nationwide, Population-Based Cohort Study. Clinical therapeutics. vol 41. issue 6. 2020-05-18. PMID:31178037. |
this study compares the risks of arrhythmia among patients with depression receiving selective serotonin reuptake inhibitors (ssris) and those receiving other classes of antidepressants and among patients with depression receiving citalopram-escitalopram and those receiving other ssris. |
2020-05-18 |
2023-08-13 |
Not clear |
| Christie Sylvester, Marie Menke, Priya Gopala. Selective Serotonin Reuptake Inhibitors and Fertility: Considerations for Couples Trying to Conceive. Harvard review of psychiatry. vol 27. issue 2. 2020-05-12. PMID:30676405. |
depression and anxiety are prevalent disorders and are often treated with selective serotonin reuptake inhibitors (ssris). |
2020-05-12 |
2023-08-13 |
Not clear |
| Jodi L Pawluski, Ursula Brain, Geoffrey L Hammond, Tim F Oberlande. Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression. Archives of women's mental health. vol 22. issue 3. 2020-05-11. PMID:30506371. |
selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression. |
2020-05-11 |
2023-08-13 |
Not clear |
| Andrew Del Colle, Narek Israelyan, Kara Gross Margoli. Novel aspects of enteric serotonergic signaling in health and brain-gut disease. American journal of physiology. Gastrointestinal and liver physiology. vol 318. issue 1. 2020-05-04. PMID:31682158. |
this review summarizes the current data focusing on the important roles that serotonin plays in ens development and motility, with a focus on novel aspects of serotonergic signaling in medical conditions in which cns and ens co-morbidities are common, including autism spectrum disorders and depression. |
2020-05-04 |
2023-08-13 |
Not clear |
| Marlene S Williams, Roy C Ziegelstein, Una D McCann, Neda F Gould, Tamara Ashvetiya, Dhananjay Vaidy. Platelet Serotonin Signaling in Patients With Cardiovascular Disease and Comorbid Depression. Psychosomatic medicine. vol 81. issue 4. 2020-04-30. PMID:30855555. |
platelet serotonin signaling in patients with cardiovascular disease and comorbid depression. |
2020-04-30 |
2023-08-13 |
Not clear |
| Marlene S Williams, Roy C Ziegelstein, Una D McCann, Neda F Gould, Tamara Ashvetiya, Dhananjay Vaidy. Platelet Serotonin Signaling in Patients With Cardiovascular Disease and Comorbid Depression. Psychosomatic medicine. vol 81. issue 4. 2020-04-30. PMID:30855555. |
the aim of the study was to examine platelet serotonin signaling in a group of patients with coronary artery disease (cad) and comorbid depression to define the relationship between platelet serotonin signaling and cardiovascular complications. |
2020-04-30 |
2023-08-13 |
Not clear |
| Lynn A Legg, Russel Tilney, Cheng-Fang Hsieh, Simiao Wu, Erik Lundström, Ann-Sofie Rudberg, Mansur A Kutlubaev, Martin Dennis, Babak Soleimani, Amanda Barugh, Maree L Hackett, Graeme J Hankey, Gillian E Mea. Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. The Cochrane database of systematic reviews. vol 2019. issue 11. 2020-04-23. PMID:31769878. |
selective serotonin reuptake inhibitors (ssris) have been used for many years to manage depression and other mood disorders after stroke. |
2020-04-23 |
2023-08-13 |
Not clear |
| M Dimitriadis, R H S van den Brink, H C Comijs, R C Oude Voshaa. Prognostic effect of serum BDNF levels in late-life depression: Moderated by childhood trauma and SSRI usage? Psychoneuroendocrinology. vol 103. 2020-04-23. PMID:30771710. |
we hypothesize that the predictive value of serum bdnf levels in late-life depression is moderated by selective serotonin reuptake inhibitors (ssri) usage and early traumatization. |
2020-04-23 |
2023-08-13 |
Not clear |
| Le Wang, Yanming Zhang, Xia Du, Teng Ding, Weiling Gong, Feng Li. Review of antidepressants in clinic and active ingredients of traditional Chinese medicine targeting 5-HT1A receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 120. 2020-04-21. PMID:31541883. |
depression is a complex disease that involves numerous factors, increasing evidences have showed that the level of 5-ht was lower in depressed patients and the administration of some selective serotonin re-uptake inhibitors exhibited antidepressant effects. |
2020-04-21 |
2023-08-13 |
Not clear |
| Naghmeh Zabolinejad, Sara Molkara, Behnoosh Bakhshodeh, Haniyeh Ghaffari-Nazari, Maryam Khoshkhu. The expression of serotonin transporter protein in the skin of patients with chronic spontaneous urticaria and its relation with depression and anxiety. Archives of dermatological research. vol 311. issue 10. 2020-04-20. PMID:31520274. |
the expression of serotonin transporter protein in the skin of patients with chronic spontaneous urticaria and its relation with depression and anxiety. |
2020-04-20 |
2023-08-13 |
Not clear |
| J John Mann, Allison V Metts, R Todd Ogden, Chester A Mathis, Harry Rubin-Falcone, Zhiqun Gong, Wayne C Drevets, Jamie Zelazny, David A Bren. Quantification of 5-HT Archives of suicide research : official journal of the International Academy for Suicide Research. vol 23. issue 1. 2020-04-16. PMID:29281590. |
quantification of 5-ht to determine serotonin system abnormalities related to major depression or previous suicidal behavior. |
2020-04-16 |
2023-08-13 |
Not clear |
| Veni Bharti, Hua Tan, Jaspreet Deol, Zijian Wu, Jun-Feng Wan. Upregulation of antioxidant thioredoxin by antidepressants fluoxetine and venlafaxine. Psychopharmacology. vol 237. issue 1. 2020-04-10. PMID:31473777. |
selective serotonin reuptake inhibitors (ssris) and serotonin-norepinephrine reuptake inhibitors (snris) are the most commonly used drugs for the treatment of depression. |
2020-04-10 |
2023-08-13 |
Not clear |