| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chen-Xin Li, Ying Zheng, Hong Zhu, Cheng-Wu Li, Zhang He, Cong Wang, Jian-Hua Ding, Gang Hu, Ming L. β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression. Acta pharmacologica Sinica. vol 42. issue 5. 2021-09-27. PMID:33526871. |
fluoxetine is the first selective serotonin reuptake inhibitor developed and is approved for the clinical treatment of depression. |
2021-09-27 |
2023-08-13 |
mouse |
| Nadine M Melhem, Yongqi Zhong, Jeffrey M Miller, Francesca Zanderigo, R Todd Ogden, M Elizabeth Sublette, Madison Newell, Ainsley Burke, John G Keilp, Mohammad Lesanpezeshki, Elizabeth Bartlett, David A Brent, J John Man. Brain 5-HT1A Receptor PET Binding, Cortisol Responses to Stress, and the Familial Transmission of Suicidal Behavior. The international journal of neuropsychopharmacology. 2021-09-23. PMID:34555145. |
the serotonin 1a (5-ht1a) receptor has been implicated in depression and suicidal behavior. |
2021-09-23 |
2023-08-13 |
Not clear |
| Felipe Dalvi-Garcia, Luis L Fonseca, Ana Tereza R Vasconcelos, Cecilia Hedin-Pereira, Eberhard O Voi. A model of dopamine and serotonin-kynurenine metabolism in cortisolemia: Implications for depression. PLoS computational biology. vol 17. issue 5. 2021-09-17. PMID:33970902. |
further model analysis demonstrated that the inhibition of both serotonin transport and kynurenine-3-monooxygenase decreased the levels of dopal and 5-hial and the neurotoxic risk often associated with depression. |
2021-09-17 |
2023-08-13 |
Not clear |
| Si-Tong Feng, Xiao-Le Wang, Ya-Ting Wang, Yu-He Yuan, Zhi-Peng Li, Nai-Hong Chen, Zhen-Zhen Wang, Yi Zhan. Efficacy of Traditional Chinese Medicine Combined with Selective Serotonin Reuptake Inhibitors on the Treatment for Parkinson's Disease with Depression: A Systematic Review and Meta-Analysis. The American journal of Chinese medicine. vol 49. issue 3. 2021-09-14. PMID:33657988. |
efficacy of traditional chinese medicine combined with selective serotonin reuptake inhibitors on the treatment for parkinson's disease with depression: a systematic review and meta-analysis. |
2021-09-14 |
2023-08-13 |
human |
| Shubhadeep Sinha, Sreenivasa Chary, Pankaj Thakur, Leela Talluri, Mohan Reddy, Kamal K Verma, Pradeep Saha, Vijaya B Gupta, Kaja A Ramaiah, Siquafa Z Khanu. A Phase III Prospective Active and Placebo-Controlled Randomized Trial of Vilazodone in the Treatment of Major Depressive Disorder. Cureus. vol 13. issue 7. 2021-09-14. PMID:34513348. |
background depression is a leading cause of psychiatric morbidity in the modern world, and the introduction of selective serotonin reuptake inhibitors (ssris) is a revolution in the treatment of depression. |
2021-09-14 |
2023-08-13 |
human |
| Heungsun Hwang, Gyeongcheol Cho, Min Jin Jin, Ji Hoon Ryoo, Younyoung Choi, Seung Hwan Le. A knowledge-based multivariate statistical method for examining gene-brain-behavioral/cognitive relationships: Imaging genetics generalized structured component analysis. PloS one. vol 16. issue 3. 2021-09-09. PMID:33690643. |
our analysis shows that a dopamine receptor gene and an interaction between a serotonin transporter gene and the environment variable have statistically significant effects on a few brain regions' variations that have statistically significant negative impacts on depression severity. |
2021-09-09 |
2023-08-13 |
human |
| Shami Kanekar, Robert Ettaro, Michael D Hoffman, Hendrik J Ombach, Jadeda Brown, Cayla Lynch, Chandni S Sheth, Perry F Rensha. Sex-Based Impact of Creatine Supplementation on Depressive Symptoms, Brain Serotonin and SSRI Efficacy in an Animal Model of Treatment-Resistant Depression. International journal of molecular sciences. vol 22. issue 15. 2021-09-08. PMID:34360959. |
sex-based impact of creatine supplementation on depressive symptoms, brain serotonin and ssri efficacy in an animal model of treatment-resistant depression. |
2021-09-08 |
2023-08-13 |
rat |
| Huan Zhang, Huanji Xu, Qiulin Tang, Feng B. The selective serotonin reuptake inhibitors enhance the cytotoxicity of sorafenib in hepatocellular carcinoma cells. Anti-cancer drugs. vol 32. issue 8. 2021-09-07. PMID:33675613. |
sertraline and fluoxetine are the two most commonly used selective serotonin reuptake inhibitors (ssris) in the treatment of depression. |
2021-09-07 |
2023-08-13 |
mouse |
| Anna U Odland, Jesper L Kristensen, Jesper T Andrease. The selective 5-HT2A receptor agonist 25CN-NBOH does not affect reversal learning in mice. Behavioural pharmacology. vol 32. issue 5. 2021-09-06. PMID:33595957. |
psychedelic 5-hydroxytryptamine 2a receptor (5-ht2ar) agonists are showing promise in the treatment of psychiatric disorders, such as treatment-resistant depression and anxiety. |
2021-09-06 |
2023-08-13 |
mouse |
| Y P Sivolap, E M Krupitsky, V D Mendelevich, K V Rybakova, M A Vinnikova, A Y Egorov, G M Uso. [Dual diagnosis: depression and alcohol use disorder]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 121. issue 7. 2021-09-06. PMID:34460170. |
the first-line antidepressants in the treatment of patients with a comorbid combination of depression and alcohol use disorder, as in other clinical situations implying use of antidepressants, are selective serotonin reuptake inhibitors (ssris). |
2021-09-06 |
2023-08-13 |
Not clear |
| Natalia Sánchez, Jesús Juárez-Balarezo, Marcia Olhaberry, Humberto González-Oneto, Antonia Muzard, María Jesús Mardonez, Pamela Franco, Felipe Barrera, Marcia Gaet. Depression and Antidepressants During Pregnancy: Craniofacial Defects Due to Stem/Progenitor Cell Deregulation Mediated by Serotonin. Frontiers in cell and developmental biology. vol 9. 2021-09-04. PMID:34476233. |
depression and antidepressants during pregnancy: craniofacial defects due to stem/progenitor cell deregulation mediated by serotonin. |
2021-09-04 |
2023-08-13 |
Not clear |
| Natalia Sánchez, Jesús Juárez-Balarezo, Marcia Olhaberry, Humberto González-Oneto, Antonia Muzard, María Jesús Mardonez, Pamela Franco, Felipe Barrera, Marcia Gaet. Depression and Antidepressants During Pregnancy: Craniofacial Defects Due to Stem/Progenitor Cell Deregulation Mediated by Serotonin. Frontiers in cell and developmental biology. vol 9. 2021-09-04. PMID:34476233. |
depression has been related to a downregulation in serotonin levels in the brain. |
2021-09-04 |
2023-08-13 |
Not clear |
| Gabriela César Falcão Vieira, Bruna Rachel de Oliveira Rodrigues, Carlos Eduardo Ximenes da Cunha, Gabriella Bento de Morais, Luiz Henrique Ribeiro de Moraes Ferreira, Marina Viegas Moura Rezende Ribeir. Depression and dry eye: a narrative review. Revista da Associacao Medica Brasileira (1992). vol 67. issue 3. 2021-09-03. PMID:34468615. |
also, the treatment of depression with selective inhibitors of serotonin receptors causes inflammatory cytokine secretion with subsequent inflammation and apoptosis of cells on the ocular surface. |
2021-09-03 |
2023-08-13 |
human |
| Aurora E Serralde-Zúñiga, Alejandro G Gonzalez Garay, Yanelli Rodríguez-Carmona, Guillermo Melende. Fluoxetine for adults who are overweight or obese. The Cochrane database of systematic reviews. vol 10. 2021-09-03. PMID:31613390. |
fluoxetine is a serotonin reuptake inhibitor indicated for major depression. |
2021-09-03 |
2023-08-13 |
Not clear |
| Minxue Shen, Duling Cao, Yi Xiao, Yehong Kuang, Danrong Jing, Yajia Li, Panpan Liu, Xiang Chen, Wu Zh. Serum 5-Hydroxytryptamine is Related to Psoriasis Severity in Patients with Comorbid Anxiety or Depression. Acta dermato-venereologica. vol 101. issue 8. 2021-09-02. PMID:34184067. |
serum 5-hydroxytryptamine is related to psoriasis severity in patients with comorbid anxiety or depression. |
2021-09-02 |
2023-08-13 |
Not clear |
| Patryk Kubiszewski, Lansing Sugita, Christina Kourkoulis, Zora DiPucchio, Kristin Schwab, Christopher D Anderson, M Edip Gurol, Steven M Greenberg, Anand Viswanathan, Jonathan Rosand, Alessandro Biff. Association of Selective Serotonin Reuptake Inhibitor Use After Intracerebral Hemorrhage With Hemorrhage Recurrence and Depression Severity. JAMA neurology. 2021-09-01. PMID:32865558. |
association of selective serotonin reuptake inhibitor use after intracerebral hemorrhage with hemorrhage recurrence and depression severity. |
2021-09-01 |
2023-08-13 |
Not clear |
| Patryk Kubiszewski, Lansing Sugita, Christina Kourkoulis, Zora DiPucchio, Kristin Schwab, Christopher D Anderson, M Edip Gurol, Steven M Greenberg, Anand Viswanathan, Jonathan Rosand, Alessandro Biff. Association of Selective Serotonin Reuptake Inhibitor Use After Intracerebral Hemorrhage With Hemorrhage Recurrence and Depression Severity. JAMA neurology. 2021-09-01. PMID:32865558. |
selective serotonin reuptake inhibitors (ssris) are widely used to treat poststroke depression but are associated with increased incidence of first-ever intracerebral hemorrhage (ich) in the general population. |
2021-09-01 |
2023-08-13 |
Not clear |
| Stephanie M Mueller, Martin Grunwal. Effects, Side Effects and Contraindications of Relaxation Massage during Pregnancy: A Systematic Review of Randomized Controlled Trials. Journal of clinical medicine. vol 10. issue 16. 2021-08-31. PMID:34441781. |
the main benefits of massage during pregnancy were: reduced stress, back and leg pain, depression and anxiety; increased immune response; increased serotonin and dopamine levels; higher fetal birth weight and reduced risk of preterm delivery. |
2021-08-31 |
2023-08-13 |
Not clear |
| Naama Rotem-Kohavi, Lynne J Williams, Tim F Oberlande. Advanced neuroimaging: A window into the neural correlates of fetal programming related to prenatal exposure to maternal depression and SSRIs. Seminars in perinatology. vol 44. issue 3. 2021-08-30. PMID:32122645. |
maternal depression and treatment with selective serotonin reuptake inhibitor (ssri) antidepressants during pregnancy are common prenatal exposures that affect critical early life developmental programming processes. |
2021-08-30 |
2023-08-13 |
Not clear |
| P Brancaleone, O Descamps, M Piquet, G Detry, M Mignon, B Weynan. [Sertraline-induced chronic eosinophilic pneumonia]. Revue des maladies respiratoires. vol 38. issue 2. 2021-08-30. PMID:33581985. |
sertraline is a selective serotonin reuptake inhibitor which is often used as first-line treatment for depression. |
2021-08-30 |
2023-08-13 |
Not clear |