| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Pertz, S El. In-vitro pharmacology of sarpogrelate and the enantiomers of its major metabolite: 5-HT2A receptor specificity, stereoselectivity and modulation of ritanserin-induced depression of 5-HT contractions in rat tail artery. The Journal of pharmacy and pharmacology. vol 47. issue 4. 1995-07-27. PMID:7791029. |
in-vitro pharmacology of sarpogrelate and the enantiomers of its major metabolite: 5-ht2a receptor specificity, stereoselectivity and modulation of ritanserin-induced depression of 5-ht contractions in rat tail artery. |
1995-07-27 |
2023-08-12 |
rat |
| E Le Poul, L Lima, A M Laporte, C Even, E Doucet, C M Fattaccini, N Laaris, M Hamon, L Lanfume. [Central serotonin receptors and chronic treatment with selective serotonin reuptake inhibitors in the rat: comparative effects of fluoxetine and paroxetine]. L'Encephale. vol 21. issue 2. 1995-07-20. PMID:7781583. |
the hypothesis that a dysfunction of serotonergic neurotransmission is implicated in depression is supported by the clinical efficiency of selective serotonin (5-hydroxytryptamine, 5-ht) reuptake inhibitors (ssris) in the treatment of depressive disorders. |
1995-07-20 |
2023-08-12 |
rat |
| G Andersen, K Vestergaard, L U Lauritze. [Effective treatment of depression following apoplexy with citalopram]. Ugeskrift for laeger. vol 157. issue 14. 1995-06-05. PMID:7740639. |
the aim of the study was to investigate the efficacy and safety of the selective serotonin reuptake inhibitor citalopram in treating post-stroke depression. |
1995-06-05 |
2023-08-12 |
Not clear |
| G Andersen, K Vestergaard, L U Lauritze. [Effective treatment of depression following apoplexy with citalopram]. Ugeskrift for laeger. vol 157. issue 14. 1995-06-05. PMID:7740639. |
the trial demonstrates that the selective serotonin reuptake inhibitor citalopram offers an advantageous new treatment of post-stroke depression that is both safe and effective. |
1995-06-05 |
2023-08-12 |
Not clear |
| E G Hantouche, S Lancrenon, J M Chigno. [Effect of antidepressant treatment on sense of dyscontrol: preliminary studies]. L'Encephale. vol 21. issue 1. 1995-05-25. PMID:7720623. |
cumulative data in the field of phenomenology, neurobiology and psychopharmacology indicate "discontrol" as a dimension probably linked to serotonin central activity and frequently observed in major depression and other related disorders. |
1995-05-25 |
2023-08-12 |
Not clear |
| K P Lesch, J Gross, E Franzek, B L Wolozin, P Riederer, D L Murph. Primary structure of the serotonin transporter in unipolar depression and bipolar disorder. Biological psychiatry. vol 37. issue 4. 1995-05-18. PMID:7711157. |
primary structure of the serotonin transporter in unipolar depression and bipolar disorder. |
1995-05-18 |
2023-08-12 |
Not clear |
| K P Lesch, J Gross, E Franzek, B L Wolozin, P Riederer, D L Murph. Primary structure of the serotonin transporter in unipolar depression and bipolar disorder. Biological psychiatry. vol 37. issue 4. 1995-05-18. PMID:7711157. |
decreased platelet serotonin (5-ht) transport and reduced binding of imipramine or paroxetine to brain and platelet 5-ht uptake sites/transporters in patients with depression and suicide victims define the 5-ht transporter (5-htt) as a candidate gene. |
1995-05-18 |
2023-08-12 |
Not clear |
| J Penttine. Hypothesis: low serum cholesterol, suicide, and interleukin-2. American journal of epidemiology. vol 141. issue 8. 1995-05-09. PMID:7709913. |
it has been suggested that low cholesterol is associated with depression by modifying the serotonin metabolism. |
1995-05-09 |
2023-08-12 |
Not clear |
| M Mae. Evidence for an immune response in major depression: a review and hypothesis. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 1. 1995-05-05. PMID:7708925. |
it is hypothesized that increased monocytic production of interleukins (il-1 beta and il-6) in severe depression may constitute key phenomena underlying the various aspects of the immune and "acute" phase response, while contributing to hypothalamic-pituitary-adrenal-axis hyperactivity, disorders in serotonin metabolism, and to the vegetative symptoms (i.e. |
1995-05-05 |
2023-08-12 |
Not clear |
| J Karle, F Bjørnda. [Serotonergic syndrome--in combination therapy with lithium and fluoxetine]. Ugeskrift for laeger. vol 157. issue 9. 1995-05-03. PMID:7701669. |
serotonin syndrome is expected to occur more frequently with the increased use of specific serotonin reuptake inhibitors in the treatment of depression. |
1995-05-03 |
2023-08-12 |
Not clear |
| R M Salomon, P L Delgado, J Licinio, J H Krystal, G R Heninger, D S Charne. Effects of sleep deprivation on serotonin function in depression. Biological psychiatry. vol 36. issue 12. 1995-04-26. PMID:7893848. |
effects of sleep deprivation on serotonin function in depression. |
1995-04-26 |
2023-08-12 |
Not clear |
| I M Anderson, K Scott, G Harborn. Serotonin and depression in frontal lobe dementia. The American journal of psychiatry. vol 152. issue 4. 1995-04-25. PMID:7694920. |
serotonin and depression in frontal lobe dementia. |
1995-04-25 |
2023-08-12 |
Not clear |
| M Maes, H Y Meltzer, P D'Hondt, P Cosyns, P Block. Effects of serotonin precursors on the negative feedback effects of glucocorticoids on hypothalamic-pituitary-adrenal axis function in depression. Psychoneuroendocrinology. vol 20. issue 2. 1995-04-25. PMID:7899535. |
effects of serotonin precursors on the negative feedback effects of glucocorticoids on hypothalamic-pituitary-adrenal axis function in depression. |
1995-04-25 |
2023-08-12 |
human |
| G Kh Bozhko, V I Tsaritsinskiĭ, L S Kostiukovskaia, V M Kulabukho. [The effect of an increased intensity of light on changes in the serotonin and melatonin content in patients with depression]. Likars'ka sprava. issue 7-8. 1995-04-24. PMID:7900366. |
[the effect of an increased intensity of light on changes in the serotonin and melatonin content in patients with depression]. |
1995-04-24 |
2023-08-12 |
Not clear |
| D B Montgomery, A Roberts, M Green, T Bullock, D Baldwin, S A Montgomer. Lack of efficacy of fluoxetine in recurrent brief depression and suicidal attempts. European archives of psychiatry and clinical neuroscience. vol 244. issue 4. 1995-04-20. PMID:7888419. |
the possibility that antidepressants with selective action on the reuptake of serotonin might be effective in preventing recurrences of brief depression has been investigated. |
1995-04-20 |
2023-08-12 |
Not clear |
| D C Manoli. The perils of Prozac. Minnesota medicine. vol 78. issue 1. 1995-03-31. PMID:7794331. |
prozac and the other selective serotonin re-uptake inhibitors have been determined to be safe and effective treatment for depression. |
1995-03-31 |
2023-08-12 |
Not clear |
| K M Lawrence, J Falkowski, R R Jacobson, R W Horto. Platelet 5-HT uptake sites in depression: three concurrent measures using [3H] imipramine and [3H] paroxetine. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870891. |
platelet 5-ht uptake sites in depression: three concurrent measures using [3h] imipramine and [3h] paroxetine. |
1995-03-29 |
2023-08-12 |
human |
| K M Lawrence, J Falkowski, R R Jacobson, R W Horto. Platelet 5-HT uptake sites in depression: three concurrent measures using [3H] imipramine and [3H] paroxetine. Psychopharmacology. vol 110. issue 1-2. 1995-03-29. PMID:7870891. |
this study provides no support for the view that the number of platelet 5-ht uptake sites are reduced in depression. |
1995-03-29 |
2023-08-12 |
human |
| P D Hrdina, D Bakish, J Chudzik, A Ravindran, Y D Lapierr. Serotonergic markers in platelets of patients with major depression: upregulation of 5-HT2 receptors. Journal of psychiatry & neuroscience : JPN. vol 20. issue 1. 1995-03-27. PMID:7865496. |
the uptake of [3h]5-ht and the density (bmax) as well as affinity (kd) of 5-ht uptake sites labelled with [3h]paroxetine and of 5-ht2 receptors labelled by [3h]lsd were determined in platelets from 25 medication-free patients with major depression and 20 normal controls. |
1995-03-27 |
2023-08-12 |
human |
| R C Shelto. The role of sertraline in the management of depression. Clinical therapeutics. vol 16. issue 5. 1995-03-21. PMID:7859236. |
this serotonin reuptake inhibitor shows promise as an important therapeutic and prophylactic alternative in the pharmacologic management of depression. |
1995-03-21 |
2023-08-12 |
Not clear |