| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C A Stockmeier, G E Dilley, L A Shapiro, J C Overholser, P A Thompson, H Y Meltze. Serotonin receptors in suicide victims with major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 16. issue 2. 1997-04-15. PMID:9015799. |
serotonin receptors in suicide victims with major depression. |
1997-04-15 |
2023-08-12 |
human |
| I Karlsso. Treatment of non-cognitive symptoms in dementia. Acta neurologica Scandinavica. Supplementum. vol 168. 1997-04-09. PMID:8997427. |
specific serotonin re-uptake inhibitors (ssri) are efficient in the treatment of both depression and anxiety while tricyclic antidepressants have side effects including cognitive reduction. |
1997-04-09 |
2023-08-12 |
Not clear |
| S B Park, D J Williamson, P J Cowe. 5-HT neuroendocrine function in major depression: prolactin and cortisol responses to D-fenfluramine. Psychological medicine. vol 26. issue 6. 1997-04-08. PMID:8931165. |
5-ht neuroendocrine function in major depression: prolactin and cortisol responses to d-fenfluramine. |
1997-04-08 |
2023-08-12 |
Not clear |
| M Maes, E Vandoolaeghe, R Desnyde. Efficacy of treatment with trazodone in combination with pindolol or fluoxetine in major depression. Journal of affective disorders. vol 41. issue 3. 1997-04-02. PMID:8988452. |
fluoxetine, a selective serotonin (5-ht) reuptake inhibitor (ssri), and trazodone, a heterocyclic antidepressant, are effective in the treatment of major depression and treatment resistant depression (trd). |
1997-04-02 |
2023-08-12 |
Not clear |
| M Maes, E Vandoolaeghe, R Desnyde. Efficacy of treatment with trazodone in combination with pindolol or fluoxetine in major depression. Journal of affective disorders. vol 41. issue 3. 1997-04-02. PMID:8988452. |
it has been shown that pindolol, a serotonin (5-ht)1a-receptor antagonist, may shorten the latency of onset of ssris in depression. |
1997-04-02 |
2023-08-12 |
Not clear |
| T A Slotkin, E C McCook, J C Ritchie, B J Carroll, F J Seidle. Serotonin transporter expression in rat brain regions and blood platelets: aging and glucocorticoid effects. Biological psychiatry. vol 41. issue 2. 1997-04-02. PMID:9018387. |
the results suggest that there are basic biologic differences in the effects of glucocorticoids in aged vs. young brain that could contribute to lowered effectiveness to antidepressants in elderly depression; if transport capacity is already reduced by the effects of increased glucocorticoids, further inhibition of transport by antidepressants would have proportionally less impact on synaptic serotonin concentrations. |
1997-04-02 |
2023-08-12 |
rat |
| D Bakish, P Cavazzoni, J Chudzik, A Ravindran, P D Hrdin. Effects of selective serotonin reuptake inhibitors on platelet serotonin parameters in major depressive disorder. Biological psychiatry. vol 41. issue 2. 1997-04-02. PMID:9018388. |
the effects of treatment with serotonin (5-ht) reuptake inhibitors on platelet 5-ht2 receptors, 5-ht reuptake sites an 5-ht uptake were studied in a double-blind trial comparing two selective serotonin reuptake inhibitors (ssri), paroxetine, and fluoxetine, for the treatment of major depression. |
1997-04-02 |
2023-08-12 |
Not clear |
| D Bakish, P Cavazzoni, J Chudzik, A Ravindran, P D Hrdin. Effects of selective serotonin reuptake inhibitors on platelet serotonin parameters in major depressive disorder. Biological psychiatry. vol 41. issue 2. 1997-04-02. PMID:9018388. |
hamilton depression rating scale (ham-d) scores and platelet 5-ht parameters were determined in 21 depressed patients at baseline, after 4 and 8 weeks of treatment, and were compared to 21 healthy controls. |
1997-04-02 |
2023-08-12 |
Not clear |
| A Reipschläger, G E Nilsson, H O Pörtne. A role for adenosine in metabolic depression in the marine invertebrate Sipunculus nudus. The American journal of physiology. vol 272. issue 1 Pt 2. 1997-03-31. PMID:9039028. |
among amino acids (gamma-aminobutyric acid, glutamate, glycine, taurine, serine, and aspartate) and monoamines (serotonin, dopamine, and norepinephrine), some changes were significant, but none were consistent with metabolic depression under all experimental conditions applied. |
1997-03-31 |
2023-08-12 |
Not clear |
| G M Brow. Reduced serotonin responsivity in depression. The American journal of psychiatry. vol 154. issue 3. 1997-03-26. PMID:9054808. |
reduced serotonin responsivity in depression. |
1997-03-26 |
2023-08-12 |
Not clear |
| J E Menting, A Honig, F R Verhey, M Hartmans, N Rozendaal, H C de Vet, H M van Praa. Selective serotonin reuptake inhibitors (SSRIs) in the treatment of elderly depressed patients: a qualitative analysis of the literature on their efficacy and side-effects. International clinical psychopharmacology. vol 11. issue 3. 1997-03-19. PMID:8923095. |
a qualitative analysis of studies on the efficacy and side-effects of selective serotonin reuptake inhibitors (ssris) for the treatment of elderly people with depression is presented. |
1997-03-19 |
2023-08-12 |
Not clear |
| Y Lecrubier, Y Pletan, A Solles, A Tournoux, V Magn. Clinical efficacy of milnacipran: placebo-controlled trials. International clinical psychopharmacology. vol 11 Suppl 4. 1997-03-19. PMID:8923124. |
the clinical efficacy of milnacipran, a selective serotonin and noradrenaline reuptake inhibitor, was reviewed on the basis of three, multicentre, placebo-controlled trials in major depression. |
1997-03-19 |
2023-08-12 |
Not clear |
| J Lopez-Ibor, J D Guelfi, Y Pletan, A Tournoux, J F Pros. Milnacipran and selective serotonin reuptake inhibitors in major depression. International clinical psychopharmacology. vol 11 Suppl 4. 1997-03-19. PMID:8923126. |
milnacipran and selective serotonin reuptake inhibitors in major depression. |
1997-03-19 |
2023-08-12 |
Not clear |
| J Lopez-Ibor, J D Guelfi, Y Pletan, A Tournoux, J F Pros. Milnacipran and selective serotonin reuptake inhibitors in major depression. International clinical psychopharmacology. vol 11 Suppl 4. 1997-03-19. PMID:8923126. |
selectivity for the single neurotransmitter, serotonin, may explain why ssris tend to be less efficacious than the tcas, especially in more serious forms of depression. |
1997-03-19 |
2023-08-12 |
Not clear |
| S D Hor. Overcoming obstacles to effective treatment: use of clinical practice improvement methodology. The Journal of clinical psychiatry. vol 58 Suppl 1. 1997-03-19. PMID:9054904. |
among the findings were the following: (1) the majority of patients receiving psychiatric drugs do not have a specific psychiatric diagnosis; (2) a significant proportion of patients with a specific diagnosis of major depression do not receive antidepressant medication; (3) cost-containment strategies appeared to markedly limit psychiatric referral and frequency of visits and use of serotonin selective reuptake inhibitor treatment; and (4) severity of the primary illness in the study population was markedly increased in patients with a psychiatric diagnosis. |
1997-03-19 |
2023-08-12 |
Not clear |
| E Davids, K P Lesc. [The 5-HT1A receptor: a new effective principle in psychopharmacologic therapy?]. Fortschritte der Neurologie-Psychiatrie. vol 64. issue 11. 1997-03-18. PMID:9064274. |
preliminary results suggest that beta-adrenoceptor blockers may be useful as adjunctive medication in the treatment of depression by augmenting the antidepressant efficacy of selective serotonin reuptake inhibitors. |
1997-03-18 |
2023-08-12 |
Not clear |
| D D Walczak, J T Apter, J A Halikas, R L Borison, J S Carman, G L Post, R Patrick, J B Cohn, L A Cunningham, B Rittberg, S H Preskorn, J S Kang, C S Wilco. The oral dose-effect relationship for fluvoxamine: a fixed-dose comparison against placebo in depressed outpatients. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 8. issue 3. 1997-03-14. PMID:8899132. |
a 13-item subscore of the standard 21-item hamilton depression scale was used to minimize the possible contribution of known side effects from serotonin reuptake inhibitors to the overall ham-d score. |
1997-03-14 |
2023-08-12 |
Not clear |
| A Cappiello, R T Malison, C J McDougle, S J Vegso, D S Charney, G R Heninger, L H Pric. Seasonal variation in neuroendocrine and mood responses to i.v. L-tryptophan in depressed patients and healthy subjects. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 5. 1997-03-14. PMID:8914120. |
these data support previous evidence that 5-ht function is abnormal in depression and further suggest a seasonal variability of such abnormalities that is absent in healthy subjects. |
1997-03-14 |
2023-08-12 |
human |
| A Neumeister, N Praschak-Rieder, B Besselmann, M L Rao, J Glück, S Kaspe. Effects of tryptophan depletion on drug-free patients with seasonal affective disorder during a stable response to bright light therapy. Archives of general psychiatry. vol 54. issue 2. 1997-03-13. PMID:9040281. |
light therapy-induced remission from depression may be associated with changes in brain serotonin function. |
1997-03-13 |
2023-08-12 |
Not clear |
| A González-Pinto, J J López Ibor, J Sáiz, M Gutiérrez, J L Figuerido, M J García Godo. [The clomipramine test and subtypes of depression]. Actas luso-espanolas de neurologia, psiquiatria y ciencias afines. vol 24. issue 6. 1997-03-12. PMID:9054201. |
in this study, the neuroendocrine responses to acute intravenous administration of the serotonin (5-ht) reuptake inhibitor clomipramine were assessed in patients with major depression with melancholia (dmm) and matched subjects with major depression (dm) (without melancholia) and dysthimic disorder (td). |
1997-03-12 |
2023-08-12 |
human |