| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D A Collier, M J Arranz, P Sham, S Battersby, H Vallada, P Gill, K J Aitchison, M Sodhi, T Li, G W Roberts, B Smith, J Morton, R M Murray, D Smith, G Kiro. The serotonin transporter is a potential susceptibility factor for bipolar affective disorder. Neuroreport. vol 7. issue 10. 1997-02-12. PMID:8904780. |
we analysed a vntr in intron 2 of the human serotonin transporter gene (hsert) for allelic association with bipolar affective disorder, unipolar depression and schizophrenia. |
1997-02-12 |
2023-08-12 |
human |
| C A Glo. Recent advances in the pharmacotherapy of major depression. Archives of psychiatric nursing. vol 10. issue 6. 1997-02-12. PMID:8987206. |
this review highlights key features of several newer antidepressants: three selective serotonin reuptake inhibitors approved for major depression (fluoxetine [prozac, dista, indianapolis, in], sertraline [zoloft, roerig, new york, ny], and paroxetine [paxil, smithkline beecham, philadelphia, pa]), a serotonin-norepinephrine reuptake inhibitor venlafaxine (effexor, wyeth-ayerst, philadelphia, pa), and nefazodone (serzone, bristol-myers squibb, princeton, nj). |
1997-02-12 |
2023-08-12 |
Not clear |
| O Spreux-Varoquaux, J Gailledreau, B Vanier, D Bothua, J Plas, J F Chevalier, C Advenier, M Pays, S Brio. Initial increase of plasma serotonin: a biological predictor for the antidepressant response to clomipramine? Biological psychiatry. vol 40. issue 6. 1997-02-03. PMID:8879466. |
hypofunction of the serotonin (5-ht) system might be involved in depression. |
1997-02-03 |
2023-08-12 |
Not clear |
| S Yamawaki, A Kagaya, Y Okamoto, M Shimizu, A Nishida, Y Uchitom. Enhanced calcium response to serotonin in platelets from patients with affective disorders. Journal of psychiatry & neuroscience : JPN. vol 21. issue 5. 1997-02-03. PMID:8973051. |
in this report we have investigated the intracellular calcium (ca2+) mobilization mediated by serotonin 5-ht2a receptors in the platelets of 13 patients with bipolar disorder and 12 patients with major depression in comparison with 15 healthy control subjects. |
1997-02-03 |
2023-08-12 |
human |
| S Yamawaki, A Kagaya, Y Okamoto, M Shimizu, A Nishida, Y Uchitom. Enhanced calcium response to serotonin in platelets from patients with affective disorders. Journal of psychiatry & neuroscience : JPN. vol 21. issue 5. 1997-02-03. PMID:8973051. |
we found an enhanced intracellular ca2+ rise in response to 5-ht in platelets from both bipolar patients and patients with major depression. |
1997-02-03 |
2023-08-12 |
human |
| P Hertel, G G Nomikos, M Iurlo, T H Svensso. Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain. Psychopharmacology. vol 124. issue 1-2. 1997-01-29. PMID:8935802. |
the preferential activation of 5-ht release and metabolism in frontal cortical areas might be of particular relevance for the ameliorating effect of risperidone on negative symptoms in schizophrenia, especially when associated with depression. |
1997-01-29 |
2023-08-12 |
rat |
| K J Weis. Optimal management of anxiety in older patients. Drugs & aging. vol 9. issue 3. 1997-01-21. PMID:8877313. |
the selective serotonin reuptake inhibitors appear to be better suited to treating syndromes such as panic and obsessive-compulsive disorder, whereas nefazodone would be a better choice for generalised anxiety complicated by depression. |
1997-01-21 |
2023-08-12 |
Not clear |
| J R Brubacher, R S Hoffman, M J Luri. Serotonin syndrome from venlafaxine-tranylcypromine interaction. Veterinary and human toxicology. vol 38. issue 5. 1997-01-21. PMID:8888541. |
we report a venlafaxine-maoi interaction that resulted in the serotonin syndrome in a 23-y-old male who was taking tranylcypromine for depression. |
1997-01-21 |
2023-08-12 |
Not clear |
| D F Papolos, Y M Yu, E Rosenbaum, H M Lachma. Modulation of learned helplessness by 5-hydroxytryptamine2A receptor antisense oligodeoxynucleotides. Psychiatry research. vol 63. issue 2-3. 1997-01-16. PMID:8878316. |
to understand the significance of neuronal responses in depression and lh that are mediated by serotonin (5-hydroxytryptamine, 5ht) receptors, we used intracerebroventricular injections to introduce a unique antisense oligonucleotide (aso) to the 5ht2a receptor and determined its effect on lh behavior in sprague-dawley rats as determined by an escape-avoidance strategy. |
1997-01-16 |
2023-08-12 |
rat |
| D F Papolos, Y M Yu, E Rosenbaum, H M Lachma. Modulation of learned helplessness by 5-hydroxytryptamine2A receptor antisense oligodeoxynucleotides. Psychiatry research. vol 63. issue 2-3. 1997-01-16. PMID:8878316. |
these data support the view that central 5ht, mediated by the 5ht2a receptor, participates in regulating behaviors that are affected by inescapable stress, and that the induction of behavioral depression may be specifically regulated via serotonergic pathways that terminate in this hippocampal subfield. |
1997-01-16 |
2023-08-12 |
rat |
| G E Ruof. Depression in the patient with chronic pain. The Journal of family practice. vol 43. issue 6 Suppl. 1997-01-15. PMID:8969710. |
regardless of their etiology, evidence exists to suggest that depression and chronic pain share common biologic pathways, namely, the serotonergic (5-ht) and noradrenergic systems. |
1997-01-15 |
2023-08-12 |
Not clear |
| G E Ruof. Depression in the patient with chronic pain. The Journal of family practice. vol 43. issue 6 Suppl. 1997-01-15. PMID:8969710. |
the newer antidepressants, including the selective serotonin reuptake inhibitors venlafaxine and nefazodone, are therapeutic options for the treatment of depression in the patient with chronic pain. |
1997-01-15 |
2023-08-12 |
Not clear |
| P J Perr. Pharmacotherapy for major depression with melancholic features: relative efficacy of tricyclic versus selective serotonin reuptake inhibitor antidepressants. Journal of affective disorders. vol 39. issue 1. 1997-01-14. PMID:8835647. |
pharmacotherapy for major depression with melancholic features: relative efficacy of tricyclic versus selective serotonin reuptake inhibitor antidepressants. |
1997-01-14 |
2023-08-12 |
Not clear |
| P J Perr. Pharmacotherapy for major depression with melancholic features: relative efficacy of tricyclic versus selective serotonin reuptake inhibitor antidepressants. Journal of affective disorders. vol 39. issue 1. 1997-01-14. PMID:8835647. |
the effectiveness of tricyclic antidepressants (tcas) and selective serotonin reuptake inhibitors (ssris) were contrasted in endogenous/melancholic depression. |
1997-01-14 |
2023-08-12 |
Not clear |
| D Mück-Seler, M Jakovljević, N Piva. Platelet 5-HT concentrations and suicidal behaviour in recurrent major depression. Journal of affective disorders. vol 39. issue 1. 1997-01-14. PMID:8835656. |
platelet 5-ht concentrations and suicidal behaviour in recurrent major depression. |
1997-01-14 |
2023-08-12 |
Not clear |
| J Tiihonen, M Kuoppamäki, K Någren, J Bergman, E Eronen, E Syvälahti, J Hietal. Serotonergic modulation of striatal D2 dopamine receptor binding in humans measured with positron emission tomography. Psychopharmacology. vol 126. issue 4. 1997-01-10. PMID:8878342. |
citalopram is a selective serotonin reuptake inhibitor widely used in the treatment of depression (20-40 mg/day). |
1997-01-10 |
2023-08-12 |
human |
| A Suwalska, J Rybakowsk. [Biological mechanisms of drug-resistant depression]. Psychiatria polska. vol 30. issue 5. 1997-01-08. PMID:8984513. |
efficacy of therapeutic strategies enhancing serotonergic function such as potentiation of tricyclic antidepressants with lithium or fluoxetine as well as effectiveness of selective serotonin reuptake inhibitors in drug-resistant depression may support this hypothesis. |
1997-01-08 |
2023-08-12 |
Not clear |
| L J Albers, C Reist, D Helmeste, R Vu, S W Tan. Paroxetine shifts imipramine metabolism. Psychiatry research. vol 59. issue 3. 1997-01-02. PMID:8930024. |
the combination of selective serotonin reuptake inhibitors with tricyclic antidepressants has proven useful in treatment-resistant depression but has the potential for adverse drug-drug interactions. |
1997-01-02 |
2023-08-12 |
Not clear |
| G R Heninger, P L Delgado, D S Charne. The revised monoamine theory of depression: a modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans. Pharmacopsychiatry. vol 29. issue 1. 1996-12-23. PMID:8852528. |
in order to test this hypothesis and more fully characterize the role of serotonin and catecholamines in the pathophysiology of depression and the mechanism of action of antidepressant treatments, our research group has conducted a series of studies evaluating monoamine depletion induced brief clinical relapse following different types of antidepressant treatment of depressed patients. |
1996-12-23 |
2023-08-12 |
Not clear |
| M E Bradley, E F Foote, E N Lee, L Merkl. Sertraline-associated syndrome of inappropriate antidiuretic hormone: case report and review of the literature. Pharmacotherapy. vol 16. issue 4. 1996-12-19. PMID:8840376. |
selective serotonin reuptake inhibitors have gained widespread use in the treatment of depression. |
1996-12-19 |
2023-08-12 |
Not clear |