| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alastair H Maclenna. Evidence-based review of therapies at the menopause. International journal of evidence-based healthcare. vol 7. issue 2. 2012-10-02. PMID:21631851. |
selective serotonin and noradrenaline re-uptake inhibitors ameliorate vasomotor symptoms and sometimes menopausal depression better than placebo. |
2012-10-02 |
2023-08-12 |
Not clear |
| C A Marsden, P Tyrer, P Casey, N Seivewrigh. Changes in human whole blood 5-hydroxytryptamine (5-HT) and platelet 5-HT uptake during treatment with paroxetine, a selective 5-HT uptake inhibitor. Journal of psychopharmacology (Oxford, England). vol 1. issue 4. 2012-10-02. PMID:22159137. |
the effects of the specific 5-hydroxytryptamine (5-ht) reuptake inhibitor parox etine on whole blood 5-ht and the uptake of (3)h-5-ht by platelets was determined in 17 patients with resistant depression. |
2012-10-02 |
2023-08-12 |
human |
| C A Marsden, P Tyrer, P Casey, N Seivewrigh. Changes in human whole blood 5-hydroxytryptamine (5-HT) and platelet 5-HT uptake during treatment with paroxetine, a selective 5-HT uptake inhibitor. Journal of psychopharmacology (Oxford, England). vol 1. issue 4. 2012-10-02. PMID:22159137. |
the results confirm that inhibition of 5-ht uptake mech anisms are associated with decreased whole blood 5-ht but that changes in whole blood 5- ht do not necessarily reflect the clinical efficacy of 5-ht uptake blocking drugs in the treatment of depression. |
2012-10-02 |
2023-08-12 |
human |
| P Tyrer, C A Marsden, P Casey, N Seivewrigh. Clinical efficacy of paroxetine in resistant depression. Journal of psychopharmacology (Oxford, England). vol 1. issue 4. 2012-10-02. PMID:22159138. |
the antidepressant effects of a specific reuptake inhibitor of 5-hydroxytryptamine (5-ht), paroxetine, were tested in 24 patients with resistant depression who had failed to respond to conventional antidepressants after at least 4 weeks of treatment. |
2012-10-02 |
2023-08-12 |
Not clear |
| M Yates, I N Ferrie. 5-HT1A Receptors in major depression. Journal of psychopharmacology (Oxford, England). vol 4. issue 2. 2012-10-02. PMID:22282930. |
the 5-ht(1a) receptor has been studied using quantitative tritium film auto radiography in post-mortem frontal cortex of 15 cases suffering from major depression and controls matched for age, sex, post-mortem delay and storage time. |
2012-10-02 |
2023-08-12 |
Not clear |
| J F Deaki. A review of clinical efficacy of 5-HT 1A agonists in anxiety and depression. Journal of psychopharmacology (Oxford, England). vol 7. issue 3. 2012-10-02. PMID:22290843. |
a review of clinical efficacy of 5-ht 1a agonists in anxiety and depression. |
2012-10-02 |
2023-08-12 |
Not clear |
| R Lane, D Baldwin, S Preskor. The SSRIs: advantages, disadvantages and differences. Journal of psychopharmacology (Oxford, England). vol 9. issue 2 Suppl. 2012-10-02. PMID:22297235. |
the highly specific mechanism of action of the selective serotonin re-uptake inhibitors (ssris) confers advantages on this group, relative to other classes of antidepressant, and thus represents a significant advance in the pharmacotherapy of depression. |
2012-10-02 |
2023-08-12 |
Not clear |
| S Montgomer. Serotonin, sertraline and depression. Journal of psychopharmacology (Oxford, England). vol 9. issue 2 Suppl. 2012-10-02. PMID:22297236. |
serotonin, sertraline and depression. |
2012-10-02 |
2023-08-12 |
Not clear |
| S Montgomer. Serotonin, sertraline and depression. Journal of psychopharmacology (Oxford, England). vol 9. issue 2 Suppl. 2012-10-02. PMID:22297236. |
sertraline is a highly selective serotonin re-uptake inhibitor (ssri) whose efficacy in depression has been established in a number of large placebo-controlled studies in patients with moderate to severe major depressive episodes (dsm-iii). |
2012-10-02 |
2023-08-12 |
Not clear |
| R Lan. The long-term management of depression. Journal of psychopharmacology (Oxford, England). vol 9. issue 2 Suppl. 2012-10-02. PMID:22297238. |
the selective serotonin re-uptake inhibitors (ssris) have been studied extensively and may be the most suitable long-term treatment for depression. |
2012-10-02 |
2023-08-12 |
Not clear |
| I M Anderson, B M Tomenso. The efficacy of selective serotonin re-uptake inhibitors in depression: a meta-analysis of studies against tricyclic antidepressants. Journal of psychopharmacology (Oxford, England). vol 8. issue 4. 2012-10-02. PMID:22298630. |
the efficacy of selective serotonin re-uptake inhibitors in depression: a meta-analysis of studies against tricyclic antidepressants. |
2012-10-02 |
2023-08-12 |
Not clear |
| A M Weinstein, D J Nut. A cognitive dysfunction in anxiety and its amelioration by effective treatment with SSRIs. Journal of psychopharmacology (Oxford, England). vol 9. issue 2. 2012-10-02. PMID:22298733. |
we assessed the processing of emotional cognitions of physical anxiety, psycho-social fears, depression and positive affect in a cohort of 15 patients with active anxiety disorder (mostly panic) in comparison with a group of 15 depressed patients and 15 recovered panic patients after treatment with antidepressants (all selective serotonin re-uptake inhibitors) and an age- and sex-matched normal control group. |
2012-10-02 |
2023-08-12 |
Not clear |
| J E Bailey, J Potokar, N Coupland, D J Nut. The 5-HT3 antagonist ondansetron reduces gastrointestinal side effects induced by a specific serotonin re-uptake inhibitor in man. Journal of psychopharmacology (Oxford, England). vol 9. issue 2. 2012-10-02. PMID:22298739. |
the selective serotonin re-uptake inhibitors (ssris) are increasingly being used to treat depression and anxiety disorders. |
2012-10-02 |
2023-08-12 |
human |
| Ej McCarty, Ww Dinsmor. Dapoxetine: an evidence-based review of its effectiveness in treatment of premature ejaculation. Core evidence. vol 7. 2012-10-02. PMID:22315582. |
historically, it has been treated with cognitive therapy, behavioral methods, and off-label use of selective serotonin reuptake inhibitors usually used to treat depression and other psychological disorders. |
2012-10-02 |
2023-08-12 |
Not clear |
| b' Rune Jonassen, Tor Endestad, Alexander Neumeister, Kari B Foss Haug, Jens P Berg, Nils I Landr\\xc3\\xb. The effects of the serotonin transporter polymorphism and age on frontal white matter integrity in healthy adult women. Frontiers in human neuroscience. vol 6. 2012-10-02. PMID:22347858.' |
the polymorphic region (5-httlpr) in the serotonin transporter gene (slc6a4) has been associated with major depression (mdd) (caspi et al., 2003). |
2012-10-02 |
2023-08-12 |
human |
| Yan Li, Letha Couch, Masahiro Higuchi, Jia-Long Fang, Lei Gu. Mitochondrial dysfunction induced by sertraline, an antidepressant agent. Toxicological sciences : an official journal of the Society of Toxicology. vol 127. issue 2. 2012-09-24. PMID:22387747. |
sertraline, a selective serotonin reuptake inhibitor, has been used for the treatment of depression. |
2012-09-24 |
2023-08-12 |
rat |
| Silvia Ravera, Johannes G Ramaekers, Lolkje T W de Jong-van den Berg, Johan J de Gie. Are selective serotonin reuptake inhibitors safe for drivers? What is the evidence? Clinical therapeutics. vol 34. issue 5. 2012-09-24. PMID:22554974. |
selective serotonin reuptake inhibitors (ssris) are widely used medications to treat several psychiatric diseases and, above all, depression. |
2012-09-24 |
2023-08-12 |
Not clear |
| P M Pitychoutis, C Dalla, A C Sideris, P A Tsonis, Z Papadopoulou-Daifot. 5-HT(1A), 5-HT(2A), and 5-HT(2C) receptor mRNA modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed. Neuroscience. vol 210. 2012-09-21. PMID:22441040. |
5-ht(1a), 5-ht(2a), and 5-ht(2c) receptor mrna modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed. |
2012-09-21 |
2023-08-12 |
rat |
| P M Pitychoutis, C Dalla, A C Sideris, P A Tsonis, Z Papadopoulou-Daifot. 5-HT(1A), 5-HT(2A), and 5-HT(2C) receptor mRNA modulation by antidepressant treatment in the chronic mild stress model of depression: sex differences exposed. Neuroscience. vol 210. 2012-09-21. PMID:22441040. |
cms and clomipramine's effects on 5-ht(1a)r, 5-ht(2a)r, and 5-ht(2c)r mrna expression were assessed by in situ hybridization histochemistry in selected subfields of the hippocampus and in the lateral orbitofrontal cortex (ofc), two regions implicated in the pathophysiology of major depression. |
2012-09-21 |
2023-08-12 |
rat |
| Andrea Cipriani, Marianna Purgato, Toshi A Furukawa, Carlotta Trespidi, Giuseppe Imperadore, Alessandra Signoretti, Rachel Churchill, Norio Watanabe, Corrado Barbu. Citalopram versus other anti-depressive agents for depression. The Cochrane database of systematic reviews. issue 7. 2012-09-21. PMID:22786497. |
citalopram, one of the first selective serotonin reuptake inhibitors (ssri) introduced in the market, is one of these antidepressant drugs that clinicians use for routine depression care. |
2012-09-21 |
2023-08-12 |
Not clear |