| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hideho Arit. [The neuroscience of suicide]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 8. 2012-10-18. PMID:22868884. |
corticotropin-releasing factor (crf)-immunoreactive varicose fibers were detected in the drn of suicide victims, suggesting that crf neurons in the paraventricular nucleus of the hypothalamus and 5-ht neurons in the drn may form a circuit in stress-induced depression. |
2012-10-18 |
2023-08-12 |
Not clear |
| Kaustav Chakraborty, Ajit Avasthi, Sandeep Grover, Suresh Kuma. Functional somatic complaints in depression: An overview. Asian journal of psychiatry. vol 3. issue 3. 2012-10-12. PMID:23051564. |
neurobiological understanding implicates neurotransmitters serotonin and norepinephrine, resultantly serotonin norepinephrine reuptake inhibitors have been found to be effective in treating functional somatic complaints in depression. |
2012-10-12 |
2023-08-12 |
human |
| Madhuchhanda Banerjee, Shabana Siddique, Anindita Dutta, Bidisha Mukherjee, Manas Ranjan Ra. Cooking with biomass increases the risk of depression in pre-menopausal women in India. Social science & medicine (1982). vol 75. issue 3. 2012-10-11. PMID:22580071. |
compared with the control group, women who cooked with biomass had a higher prevalence of depression and depleted platelet serotonin, suggesting altered serotonergic activity in the brain. |
2012-10-11 |
2023-08-12 |
Not clear |
| Jae-Min Kim, Robert Stewart, Kyung-Yeol Bae, Sung-Wan Kim, Hee-Ju Kang, Il-Seon Shin, Joon-Tae Kim, Man-Seok Park, Myung-Kyu Kim, Sung-Woo Park, Young-Hoon Kim, Jong-Keun Kim, Ki-Hyun Cho, Jin-Sang Yoo. Serotonergic and BDNF genes and risk of depression after stroke. Journal of affective disorders. vol 136. issue 3. 2012-10-09. PMID:22014446. |
polymorphisms of serotonin transporter (5-htt) and brain-derived neurotrophic factor (bdnf) have been investigated as candidate genes for post-stroke depression (psd). |
2012-10-09 |
2023-08-12 |
Not clear |
| Michael Maes, Karl Ringel, Marta Kubera, Michael Berk, Janusz Rybakowsk. Increased autoimmune activity against 5-HT: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression. Journal of affective disorders. vol 136. issue 3. 2012-10-09. PMID:22166399. |
increased autoimmune activity against 5-ht: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression. |
2012-10-09 |
2023-08-12 |
Not clear |
| Michael Maes, Karl Ringel, Marta Kubera, Michael Berk, Janusz Rybakowsk. Increased autoimmune activity against 5-HT: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression. Journal of affective disorders. vol 136. issue 3. 2012-10-09. PMID:22166399. |
there is evidence that the inflammatory response in depression causes dysfunctions in the metabolism of 5-ht, e.g. |
2012-10-09 |
2023-08-12 |
Not clear |
| Hans Jörgen Grabe, Christian Schwahn, Jessie Mahler, Andrea Schulz, Carsten Spitzer, Kristin Fenske, Katja Appel, Sven Barnow, Matthias Nauck, Georg Schomerus, Reiner Biffar, Dieter Rosskopf, Ulrich John, Henry Völzke, Harald Jürgen Freyberge. Moderation of adult depression by the serotonin transporter promoter variant (5-HTTLPR), childhood abuse and adult traumatic events in a general population sample. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 159B. issue 3. 2012-10-05. PMID:22328412. |
moderation of adult depression by the serotonin transporter promoter variant (5-httlpr), childhood abuse and adult traumatic events in a general population sample. |
2012-10-05 |
2023-08-12 |
human |
| M H Pollack, P C Marzo. Pharmacotherapeutic options in the treatment of comorbid depression and anxiety. CNS spectrums. vol 5. issue 12. 2012-10-02. PMID:17545962. |
medications such as tricyclic antidepressants, selective serotonin reuptake inhibitors, nefazodone, venlafaxine xr (extended release) and mirtazapine, are highly effective in treating comorbid depression and anxiety. |
2012-10-02 |
2023-08-12 |
Not clear |
| J L Elmor. SSRI Reduction of Nonparaphilic Sexual Addiction. CNS spectrums. vol 5. issue 11. 2012-10-02. PMID:18188149. |
the author presents two cases of nonparaphilic sexual addiction (npsa) with comorbid depression and other psychiatric disorders in which symptoms were relieved during treatment with selective serotonin reuptake inhibitors. |
2012-10-02 |
2023-08-12 |
Not clear |
| H M Pettinati, D Oslin, K Decke. Role of serotonin and serotonin-selective pharmacotherapy in alcohol dependence. CNS spectrums. vol 5. issue 2. 2012-10-02. PMID:18296997. |
the thinking is that these medications should be most useful in alcohol-dependent individuals who have more clearly delineated suggestive signs of 5-ht dysfunction, such as concomitant depression or anxiety. |
2012-10-02 |
2023-08-12 |
Not clear |
| J Donoghu. Selective serotonin reuptake inhibitor use in primary care: a 5-year naturalistic study. Clinical drug investigation. vol 16. issue 6. 2012-10-02. PMID:18370560. |
to investigate prescribing trends of selective serotonin reuptake inhibitors (ssris) during the course of the defeat depression campaign (1992 to 1996). |
2012-10-02 |
2023-08-12 |
Not clear |
| R S Lesser, J L Walters, R Khan, R Pebenito, S Kle. Improvement of Neuropsychiatric Lupus with Addition of SSRI Antidepressant/Antipsychotic Therapy. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. vol 3. issue 5. 2012-10-02. PMID:19078206. |
within 7 to 10 days of initiation of paroxetine, a selective serotonin reuptake inhibitor (ssri) and fluphenazine, an antipsychotic agent, the patient's neurovegetative symptoms of depression improved and suicidality remitted. |
2012-10-02 |
2023-08-12 |
Not clear |
| Chikako Kiyohara, Kouichi Yoshimas. Molecular epidemiology of major depressive disorder. Environmental health and preventive medicine. vol 14. issue 2. 2012-10-02. PMID:19568851. |
the serotonin system provides a logical source of susceptibility genes for depression, because this system is the target of selective serotonin reuptake-inhibitor drugs that are effective in treating depression. |
2012-10-02 |
2023-08-12 |
Not clear |
| H van Praa. Serotonin-related, anxiety/aggression-driven, stressor-precipitated depression. A psycho-biological hypothesis. European psychiatry : the journal of the Association of European Psychiatrists. vol 11. issue 2. 2012-10-02. PMID:19698426. |
the concept of a 5-ht related, anxiety and/or aggression-driven, stressor-precipitated depression is formulated and discussed. |
2012-10-02 |
2023-08-12 |
Not clear |
| H van Praa. Serotonin-related, anxiety/aggression-driven, stressor-precipitated depression. A psycho-biological hypothesis. European psychiatry : the journal of the Association of European Psychiatrists. vol 11. issue 2. 2012-10-02. PMID:19698426. |
in this type of depression - called 5-ht related depression - dysregulation of anxiety and/or aggression are primordial and mood lowering is a derivative phenomenon. |
2012-10-02 |
2023-08-12 |
Not clear |
| H van Praa. Serotonin-related, anxiety/aggression-driven, stressor-precipitated depression. A psycho-biological hypothesis. European psychiatry : the journal of the Association of European Psychiatrists. vol 11. issue 2. 2012-10-02. PMID:19698426. |
the 5-ht ergic impairment in certain types of depression is a trait-phenomenon, ie, persists during remission. |
2012-10-02 |
2023-08-12 |
Not clear |
| H van Praa. Serotonin-related, anxiety/aggression-driven, stressor-precipitated depression. A psycho-biological hypothesis. European psychiatry : the journal of the Association of European Psychiatrists. vol 11. issue 2. 2012-10-02. PMID:19698426. |
the exact nature of the 5-ht ergic impairment in 5-ht related depression has yet to be elucidated. |
2012-10-02 |
2023-08-12 |
Not clear |
| J Mendlewic. The broad spectrum of comorbid depression: implications for treatment. European psychiatry : the journal of the Association of European Psychiatrists. vol 13. issue 1. 2012-10-02. PMID:19698592. |
generally, the greater safety and tolerability of the selective serotonin reuptake inhibitors provides improved options for the treatment of depression in the medically and psychiatrically ill. |
2012-10-02 |
2023-08-12 |
Not clear |
| J Deaki. The role of serotonin in depression and anxiety. European psychiatry : the journal of the Association of European Psychiatrists. vol 13 Suppl 2. 2012-10-02. PMID:19698674. |
the role of serotonin in depression and anxiety. |
2012-10-02 |
2023-08-12 |
Not clear |
| J Deaki. The role of serotonin in depression and anxiety. European psychiatry : the journal of the Association of European Psychiatrists. vol 13 Suppl 2. 2012-10-02. PMID:19698674. |
there is good evidence that 5ht(1a) function breaks down in depression and causes the depressed state. |
2012-10-02 |
2023-08-12 |
Not clear |