| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B J Carroll, A Iranmanesh, D M Keenan, F Cassidy, W H Wilson, J D Veldhui. Pathophysiology of hypercortisolism in depression: pituitary and adrenal responses to low glucocorticoid feedback. Acta psychiatrica Scandinavica. vol 125. issue 6. 2012-09-06. PMID:22211368. |
pathophysiology of hypercortisolism in depression: pituitary and adrenal responses to low glucocorticoid feedback. |
2012-09-06 |
2023-08-12 |
Not clear |
| A E Kulle, M Welzel, P-M Holterhus, F G Riep. Principles and clinical applications of liquid chromatography - tandem mass spectrometry for the determination of adrenal and gonadal steroid hormones. Journal of endocrinological investigation. vol 34. issue 9. 2012-07-16. PMID:21738000. |
if these are available, lc-ms/ms can find application in congenital disorders of steroid metabolism, such as congenital adrenal hyperplasia, disorders of sex development and disorders of salt homeostasis, as well as in acquired disorders of steroid metabolism, such as primary aldosteronism, cushing's disease, addison's disease, and hyperandrogenemia, as well as in psychiatric disease states such as depression or anxiety disorders. |
2012-07-16 |
2023-08-12 |
Not clear |
| Susan S Girdler, Monica Lindgren, Patrizia Porcu, David R Rubinow, Jacqueline L Johnson, A Leslie Morro. A history of depression in women is associated with an altered GABAergic neuroactive steroid profile. Psychoneuroendocrinology. vol 37. issue 4. 2012-07-16. PMID:21890277. |
because serum neuroactive steroids are mainly synthesized in the adrenals, we hypothesize that histories of depression may be associated with persistent adrenal suppression. |
2012-07-16 |
2023-08-12 |
Not clear |
| K Sriram, Maria Rodriguez-Fernandez, Francis J Doyl. Modeling cortisol dynamics in the neuro-endocrine axis distinguishes normal, depression, and post-traumatic stress disorder (PTSD) in humans. PLoS computational biology. vol 8. issue 2. 2012-06-19. PMID:22359492. |
cortisol, secreted in the adrenal cortex in response to stress, is an informative biomarker that distinguishes anxiety disorders such as major depression and post-traumatic stress disorder (ptsd) from normal subjects. |
2012-06-19 |
2023-08-12 |
human |
| Wataru Iio, Noriko Matsukawa, Takamitsu Tsukahara, Daisuke Kohari, Atsushi Toyod. Effects of chronic social defeat stress on MAP kinase cascade. Neuroscience letters. vol 504. issue 3. 2012-03-15. PMID:21970968. |
altered body weight and enlarged adrenal glands are typical symptoms of human depression. |
2012-03-15 |
2023-08-12 |
human |
| Naoki Hiroi, Aya Yoshihara, Mariko Sue, Gen Yoshino, Mariko Hig. Central adrenal insufficiency and diabetes insipidus misdiagnosed as severe depression. Clinical medicine insights. Case reports. vol 3. 2011-11-10. PMID:21769255. |
central adrenal insufficiency and diabetes insipidus misdiagnosed as severe depression. |
2011-11-10 |
2023-08-12 |
Not clear |
| Naoki Hiroi, Aya Yoshihara, Mariko Sue, Gen Yoshino, Mariko Hig. Central adrenal insufficiency and diabetes insipidus misdiagnosed as severe depression. Clinical medicine insights. Case reports. vol 3. 2011-11-10. PMID:21769255. |
in conclusion, it is not particularly rare for adrenal insufficiency to be misdiagnosed as depression. |
2011-11-10 |
2023-08-12 |
Not clear |
| A K Jainer, M Sharma, J K Trivedt, C G Agarwal, S C Tiwar. Acth and the dexamethasone suppression test in depression. Indian journal of psychiatry. vol 34. issue 1. 2011-11-10. PMID:21776099. |
hypercortisolemia, as measured by baseline serum cortisol levels (carroll and mendels, 1976) and abnormal response to dexamethasone suppression test (dst) (carroll et at., 1981) is thought to characterize abnormal hypothalamic-pituitory- adrenal (hpa) axis functions in patients of depression. |
2011-11-10 |
2023-08-12 |
Not clear |
| Katja Wingenfeld, Detlev Nutzinger, Joachim Kauth, Dirk H Hellhammer, Stefan Lautenbache. Salivary cortisol release and hypothalamic pituitary adrenal axis feedback sensitivity in fibromyalgia is associated with depression but not with pain. The journal of pain. vol 11. issue 11. 2011-09-26. PMID:20627822. |
salivary cortisol release and hypothalamic pituitary adrenal axis feedback sensitivity in fibromyalgia is associated with depression but not with pain. |
2011-09-26 |
2023-08-12 |
human |
| Lars Vedel Kessing, Inge Stoel Willer, Ulla Knor. Volume of the adrenal and pituitary glands in depression. Psychoneuroendocrinology. vol 36. issue 1. 2011-03-31. PMID:20646833. |
volume of the adrenal and pituitary glands in depression. |
2011-03-31 |
2023-08-12 |
Not clear |
| Robert H Howlan. Use of endocrine hormones for treating depression. Journal of psychosocial nursing and mental health services. vol 48. issue 12. 2011-02-01. PMID:21117521. |
open-label and controlled studies of various drugs that directly suppress or inhibit adrenal axis function have shown some benefit for the treatment of major depression, including treatment-resistant depression. |
2011-02-01 |
2023-08-12 |
Not clear |
| Peter J Schoonheim, Antonia Chatzopoulou, Marcel J M Schaa. The zebrafish as an in vivo model system for glucocorticoid resistance. Steroids. vol 75. issue 12. 2010-12-08. PMID:20493895. |
glucocorticoid resistance also contributes to the pathogenesis of other diseases, like major depression because of the decreased negative feedback on the hypothalamic pituitary adrenal axis. |
2010-12-08 |
2023-08-12 |
zebrafish |
| Georgios Paslakis, Peter Luppa, Maria Gilles, Daniel Kopf, Bettina Hamann-Weber, Florian Lederbogen, Michael Deuschl. Venlafaxine and mirtazapine treatment lowers serum concentrations of dehydroepiandrosterone-sulfate in depressed patients remitting during the course of treatment. Journal of psychiatric research. vol 44. issue 8. 2010-08-12. PMID:20022345. |
the adrenal androgen dehydroepiandrosterone-sulfate (dhea-s) seems to be involved in the pathophysiology of depression, although its precise role in the etiology and remission of depression remains unclear. |
2010-08-12 |
2023-08-12 |
Not clear |
| George Townsend Taylor, Susan Maloney, Joshua Dearborn, Juergen Weis. Hormones in the mentally disturbed brain: steroids and peptides in the development and treatment of psychopathology. Central nervous system agents in medicinal chemistry. vol 9. issue 4. 2010-04-27. PMID:20021365. |
a story is unfolding that points to critical roles played by hypothalamic - pituitary - gonadal (hpg) and hypothalamic - pituitary - adrenal (hpa) axes on a startling array of mental disorders, from depression to dementia. |
2010-04-27 |
2023-08-12 |
Not clear |
| J GIAJA, X CHAHOVITC. Beneficial effect of barometric depression in adrenal hyperthermia. Comptes rendus hebdomadaires des seances de l'Academie des sciences. vol 224. issue 1. 2010-03-18. PMID:20255996. |
beneficial effect of barometric depression in adrenal hyperthermia. |
2010-03-18 |
2023-08-12 |
Not clear |
| Oscar D Bruno, Lea Juárez-Allen, María Alicia Rossi, Vanesa Longobard. In what clinical settings should Cushing's syndrome be suspected? Medicina. vol 69. issue 6. 2010-03-01. PMID:20053613. |
from an epidemiological point of view, cushing's syndrome is to be suspected and consequently searched for among patients with uncontrolled high blood pressure or diabetes mellitus, metabolic syndrome, polycystic ovarian syndrome, osteoporosis, depression or adrenal incidentaloma. |
2010-03-01 |
2023-08-12 |
Not clear |
| Shannon L Gourley, Jane R Taylo. Recapitulation and reversal of a persistent depression-like syndrome in rodents. Current protocols in neuroscience. vol Chapter 9. 2010-01-08. PMID:19802817. |
this unit presents rat and mouse models of depression that involve chronic oral exposure to the stress-associated adrenal hormone, corticosterone (cort), resulting in anhedonic- and helplessness-like behaviors that are persistent yet reversible by chronic antidepressant treatment. |
2010-01-08 |
2023-08-12 |
mouse |
| Julie Espallergues, Laurent Givalois, Jamal Temsamani, Claude Laruelle, Tangui Mauric. The 3beta-hydroxysteroid dehydrogenase inhibitor trilostane shows antidepressant properties in mice. Psychoneuroendocrinology. vol 34. issue 5. 2009-08-25. PMID:19117688. |
the antidepressant-like effect of trilostane was effective after a repeated treatment (2.5-20mg/kgsc twice-a-day during 7 days) or in mice submitted to a restraint stress during 21 days and showing several behavioral and physiological parameters of depression (decreased body weight, increased adrenal glands weight and anhaedonia). |
2009-08-25 |
2023-08-12 |
mouse |
| Michael C Chen, Jutta Joormann, Joachim Hallmayer, Ian H Gotli. Serotonin transporter polymorphism predicts waking cortisol in young girls. Psychoneuroendocrinology. vol 34. issue 5. 2009-08-25. PMID:19128885. |
the hypothalamic pituitary adrenal (hpa)-axis, which regulates the hormonal response to stress, has been found to be disrupted in depression. |
2009-08-25 |
2023-08-12 |
Not clear |
| Viktorija Trajkovska, Lisbeth Kirkegaard, Gesa Krey, Anders B Marcussen, Morten S Thomsen, Sabine Chourbaji, Christiane Brandwein, Stephanie Ridder, Christer Halldin, Peter Gass, Gitte M Knudsen, Susana Azna. Activation of glucocorticoid receptors increases 5-HT2A receptor levels. Experimental neurology. vol 218. issue 1. 2009-07-07. PMID:19379741. |
major depression is associated with both dysregulation of the hypothalamic pituitary adrenal axis and serotonergic deficiency, not the least of the 5-ht2a receptor. |
2009-07-07 |
2023-08-12 |
mouse |