| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Magda M Santana, Joana Rosmaninho-Salgado, Vera Cortez, Frederico C Pereira, Manuella P Kaster, Célia A Aveleira, Marisa Ferreira, Ana Rita Álvaro, Cláudia Cavada. Impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 10. 2016-07-12. PMID:26187454. |
impaired adrenal medullary function in a mouse model of depression induced by unpredictable chronic stress. |
2016-07-12 |
2023-08-13 |
mouse |
| Rivka Ben Dor, Christine E Marx, Lawrence J Shampine, David R Rubinow, Peter J Schmid. DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action. Psychopharmacology. vol 232. issue 18. 2016-03-17. PMID:26105109. |
in a previous study, the adrenal androgen dhea, a precursor of the neurosteroid androsterone, produced antidepressant and libido-enhancing effects in patients with midlife depression. |
2016-03-17 |
2023-08-13 |
Not clear |
| Emine Eren Koçak, Aygün Ertuğru. Psychiatric disorders and epigenetics. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 23. issue 2. 2016-02-01. PMID:22648875. |
studies that investigated the role of epigenetic modifications in stress and depression focused on the proteins involved in the regulation of the hypothalamo-pituitary adrenal (hpa) axis, whereas epigenetic studies of schizophrenia primarily focused on changes in the gabaergic system. |
2016-02-01 |
2023-08-12 |
Not clear |
| Keith Sudheimer, Jennifer Keller, Rowena Gomez, Lakshika Tennakoon, Allan Reiss, Amy Garrett, Heather Kenna, Ruth O'Hara, Alan F Schatzber. Decreased hypothalamic functional connectivity with subgenual cortex in psychotic major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25292261. |
dysregulation of the hypothalamic pituitary adrenal axis and hyperactivity of the subgenual cortex are both frequently observed in depression. |
2016-01-05 |
2023-08-13 |
human |
| Mario F Juruen. Early-life stress and HPA axis trigger recurrent adulthood depression. Epilepsy & behavior : E&B. vol 38. 2015-09-03. PMID:24269030. |
a significant percentage of patients with major depression have been shown to exhibit increased concentrations of cortisol, an exaggerated cortisol response to adrenocorticotropic hormone, and an enlargement of both the pituitary and adrenal glands. |
2015-09-03 |
2023-08-12 |
Not clear |
| b' Urszula Kukla, Krzysztof \\xc5\\x81abuzek, Justyna Chronowska, Marek Krzystanek, Bogus\\xc5\\x81aw Okopie\\xc5\\x8. [Mental disorders in digestive system diseases - internist\'s and psychiatrist\'s insight]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 38. issue 227. 2015-07-02. PMID:26039016.' |
the dominant mental disease mentioned in this article is depression which because of its effect on a hypothalamuspituitary- adrenal axis and on an autonomic nervous system, not only aggravates the symptoms of inflammatory bowel diseases but may accelerate their onset in genetically predisposed patients. |
2015-07-02 |
2023-08-13 |
Not clear |
| D Luppens, C Piette, R P Radermecker, G Scantamburlo, M Ansseau, W Pitcho. [Depression and type 2 diabetes: etiopathogenic analysis of a frequent comorbidity]. Revue medicale de Liege. vol 69. issue 11. 2015-04-24. PMID:25796774. |
recent advances in the neurobiology of depression have underlined the importance of markers of inflammation, neurotrophins, and hypothalamo-pituitary adrenal (hpa) axis dysfunction in the development of this pathology. |
2015-04-24 |
2023-08-13 |
Not clear |
| Clayton Peixoto, Julio Nelson Devicari Cheda, Antonio Egidio Nardi, Andre Barciela Veras, Adriana Cardos. The effects of dehydroepiandrosterone (DHEA) in the treatment of depression and depressive symptoms in other psychiatric and medical illnesses: a systematic review. Current drug targets. vol 15. issue 9. 2015-04-15. PMID:25039497. |
significant improvements related to the use of dhea in patients with depression were observed, in addition to improvements in depressive symptoms in patients with schizophrenia, anorexia nervosa, hiv and adrenal insufficiency. |
2015-04-15 |
2023-08-13 |
human |
| S C Mueller, E M Grissom, G P Dohanic. Assessing gonadal hormone contributions to affective psychopathologies across humans and animal models. Psychoneuroendocrinology. vol 46. 2015-01-06. PMID:24882164. |
to this aim, the literature was surveyed for studies that assess conditions with suspected underlying hormonal imbalances in otherwise healthy participants (e.g., premenstrual dysphoric disorder, postmenopausal depression) as well as conditions linked to congenital endocrine abnormalities (e.g., turner syndrome, klinefelter syndrome, polycystic ovary syndrome, congenital adrenal hyperplasia, familial male precocious puberty, androgen insensitivity syndrome). |
2015-01-06 |
2023-08-13 |
human |
| Cerith S Waters, Dale F Hay, Jessica R Simmonds, Stephanie H M van Gooze. Antenatal depression and children's developmental outcomes: potential mechanisms and treatment options. European child & adolescent psychiatry. vol 23. issue 10. 2014-12-05. PMID:25037152. |
biological mechanisms hypothesised to account for an association between antenatal depression and adverse offspring outcomes are first identified including the functioning of the prenatal hypothalamic pituitary adrenal (hpa) axis and epigenetic processes. |
2014-12-05 |
2023-08-13 |
Not clear |
| A F Schatzberg, J Keller, L Tennakoon, A Lembke, G Williams, F B Kraemer, J E Sarginson, L C Lazzeroni, G M Murph. HPA axis genetic variation, cortisol and psychosis in major depression. Molecular psychiatry. vol 19. issue 2. 2014-10-01. PMID:24166410. |
genetic variation underlying hypothalamic pituitary adrenal (hpa) axis overactivity in healthy controls (hcs) and patients with severe forms of major depression has not been well explored, but could explain risk for cortisol dysregulation. |
2014-10-01 |
2023-08-12 |
human |
| Angelo Compare, Cristina Zarbo, Edo Shonin, William Van Gordon, Chiara Marcon. Emotional Regulation and Depression: A Potential Mediator between Heart and Mind. Cardiovascular psychiatry and neurology. vol 2014. 2014-07-22. PMID:25050177. |
more specifically, the evidence suggests that depression and rumination affect both cognitive (e.g., impaired ability to process negative information) and neurobiological mechanisms (e.g., hypothalamic pituitary adrenal axis overactivation and higher rates of cortisol production). |
2014-07-22 |
2023-08-13 |
Not clear |
| Laura M Glynn, Elysia Poggi Davis, Curt A Sandma. New insights into the role of perinatal HPA-axis dysregulation in postpartum depression. Neuropeptides. vol 47. issue 6. 2014-07-10. PMID:24210135. |
secondary or tertiary adrenal insufficiencies of a more extreme nature, which emerge during the prenatal period, may be predictive of an extended or more pronounced postpartum hypothalamic-pituitary-adrenal refractory period, which in turn represents a risk factor for development of postpartum depression. |
2014-07-10 |
2023-08-12 |
Not clear |
| Mihaela Aldea, Lucian Craciun, Ciprian Tomuleasa, Carmen Crivi. The role of depression and neuroimmune axis in the prognosis of cancer patients. Journal of B.U.ON. : official journal of the Balkan Union of Oncology. vol 19. issue 1. 2014-05-15. PMID:24659636. |
conversely, depression supports a chronic activated hypothalamopituitary-adrenal axis (hpa) and further determines cortisol and adrenal disturbances, as well as immune dysfunction and increased cytokine production. |
2014-05-15 |
2023-08-12 |
Not clear |
| Sophie A Vreeburg, Witte J G Hoogendijk, Roel H DeRijk, Richard van Dyck, Johannes H Smit, Frans G Zitman, Brenda W J H Pennin. Salivary cortisol levels and the 2-year course of depressive and anxiety disorders. Psychoneuroendocrinology. vol 38. issue 9. 2014-05-14. PMID:23313277. |
depression and anxiety disorders have been associated with hyperactivity of the hypothalamic-pituitary adrenal (hpa) axis. |
2014-05-14 |
2023-08-12 |
Not clear |
| Tulio E Bertorini, Angel Pere. Neurologic complications of disorders of the adrenal glands. Handbook of clinical neurology. vol 120. 2014-04-22. PMID:24365350. |
excessive corticosteroid secretions in primary or secondary cushing's syndrome causes muscle weakness and behavioral disturbances, such as emotional lability and sometimes depression, while adrenal insufficiency may cause fatigue, weakness, and depression. |
2014-04-22 |
2023-08-12 |
Not clear |
| Andreas Muth, Charles Taft, Lilian Hammarstedt, Lena Björneld, Mikael Hellström, Bo Wängber. Patient-reported impacts of a conservative management programme for the clinically inapparent adrenal mass. Endocrine. vol 44. issue 1. 2014-03-31. PMID:23250632. |
to evaluate patient-reported impacts and hrql, an eight-item adrenal incidentaloma impact questionnaire was used retrospectively, together with the hospital anxiety and depression scale, and the short form-36. |
2014-03-31 |
2023-08-12 |
Not clear |
| Neelam Engineer, Lucy Darwin, Deole Nishigandh, Kandala Ngianga-Bakwin, Steve C Smith, Dimitris K Grammatopoulo. Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum. Journal of psychiatric research. vol 47. issue 9. 2014-02-14. PMID:23726670. |
women with postnatal depression (pnd) appear to have abnormal hypothalamic pituitary adrenal (hpa) axis responses to stress, which might involve a genetic variability component. |
2014-02-14 |
2023-08-12 |
Not clear |
| Sergio Rueda Alfaro, Mateu Serra-Prat, Elisabet Palomera, Immaculada Falcón, Immaculada Cadenas, Xavier Boquet, Emili Burdoy, Josep Mussoll, Pere Serra, Manuel Puig Doming. Hormonal determinants of depression and cognitive function in independently-living elders. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion. vol 55. issue 9. 2013-07-04. PMID:22974452. |
to study the potential associations among circulating insulinlike growth factor 1 (igf-1) and adrenal and gonadal steroids with cognitive status and depression in a group of independently-living elders. |
2013-07-04 |
2023-08-12 |
Not clear |
| Mi-Sook Lee, Wan-Soon Park, Young Han Kim, Seung-Hae Kwon, Yu-Jung Jang, Daeseok Han, Kyoji Morita, Song He. Antidepressant-like effects of Cortex Mori Radicis extract via bidirectional phosphorylation of glucocorticoid receptors in the hippocampus. Behavioural brain research. vol 236. issue 1. 2013-04-23. PMID:22940457. |
excessive and prolonged secretion of adrenal glucocorticoids leads to a wide range of pathophysiological processes, including depression. |
2013-04-23 |
2023-08-12 |
rat |