| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Viktorija Trajkovska, Lisbeth Kirkegaard, Gesa Krey, Anders B Marcussen, Morten S Thomsen, Sabine Chourbaji, Christiane Brandwein, Stephanie Ridder, Christer Halldin, Peter Gass, Gitte M Knudsen, Susana Azna. Activation of glucocorticoid receptors increases 5-HT2A receptor levels. Experimental neurology. vol 218. issue 1. 2009-07-07. PMID:19379741. |
major depression is associated with both dysregulation of the hypothalamic pituitary adrenal axis and serotonergic deficiency, not the least of the 5-ht2a receptor. |
2009-07-07 |
2023-08-12 |
mouse |
| E B Binder, H E Künzel, T Nickel, N Kern, A Pfennig, M Majer, M Uhr, M Ising, F Holsboe. HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients. Psychoneuroendocrinology. vol 34. issue 1. 2009-03-24. PMID:18829172. |
a concatenation of data implicates a hyperactivity of the hypothalamus pituitary adrenal (hpa)-axis in the pathogenesis of depression and its normalization as a necessary predecessor of clinical response to antidepressant drugs. |
2009-03-24 |
2023-08-12 |
Not clear |
| Burkhard Ludescher, Arif Najib, Sophia Baar, Juergen Machann, Fritz Schick, Gerhard Buchkremer, Claus D Claussen, Gerhard W Eschweile. Increase of visceral fat and adrenal gland volume in women with depression: preliminary results of a morphometric MRI study. International journal of psychiatry in medicine. vol 38. issue 3. 2009-01-23. PMID:19069569. |
depression is often accompanied by increased visceral adipose tissue (vat), stress, enlarged adrenal glands, and an increased risk of cardiovascular disease. |
2009-01-23 |
2023-08-12 |
Not clear |
| Daisuke Obinata, Kenya Yamaguchi, Daisaku Hirano, Toshio Yoshida, Masayoshi Soma, Satoru Takahash. Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances. International journal of urology : official journal of the Japanese Urological Association. vol 15. issue 4. 2008-06-04. PMID:18380829. |
a 56-year-old woman suffered from severe depression due to cushing's syndrome with right adrenal adenoma. |
2008-06-04 |
2023-08-12 |
Not clear |
| Michael R Irwi. Human psychoneuroimmunology: 20 years of discovery. Brain, behavior, and immunity. vol 22. issue 2. 2008-02-05. PMID:17911004. |
as such, this review provides a perspective from our laboratory over the last 20 years to define the inter-relationships between behavior and immunity; to identify the hypothalamic pituitary adrenal (hpa) and autonomic mechanisms that link the central nervous system and immune responses; to examine the clinical implications of immune alterations during depression or life stress on inflammatory and infectious disease risk; and to explore the reciprocal role of immune mediators on behavior in humans. |
2008-02-05 |
2023-08-12 |
human |
| Olfa Chehab, Mohamed Ouertani, Kamel Chaieb, Faouzi Haouala, Kacem Mahdouan. Hormonal status of cortisol and dehydroepiandrosterone sulfate in an elderly Tunisian population. Comptes rendus biologies. vol 330. issue 10. 2008-01-23. PMID:17905395. |
generally, the adrenal insufficiency marked by a cognitive impairment, immune disorders, sexual dysfunction, and scores for depression and anxiety can be corrected by a replacement of deficient dhea-s. |
2008-01-23 |
2023-08-12 |
Not clear |
| Perrie F O'Tierney, M Yat Tse, Stephen C Pan. Elevated renal norepinephrine in proANP gene-disrupted mice is associated with increased tyrosine hydroxylase expression in sympathetic ganglia. Regulatory peptides. vol 143. issue 1-3. 2007-11-06. PMID:17482290. |
anp's sympatholytic properties include the depression of ganglionic and adrenal th expression and catecholamine production. |
2007-11-06 |
2023-08-12 |
mouse |
| b' Ricard Navin\\xc3\\xa9s, Esther G\\xc3\\xb3mez-Gil, Roc\\xc3\\xado Mart\\xc3\\xadn-Santos, Mar\\xc3\\xada J Mart\\xc3\\xadnez de Osaba, Gin\\xc3\\xa9s Escolar, Crist\\xc3\\xb3bal Gast\\xc3\\xb. Hormonal response to buspirone is not impaired in major depression. Human psychopharmacology. vol 22. issue 6. 2007-10-23. PMID:17563921.' |
it has been suggested that interactions between hypothalamic pituitary adrenal (hpa) axis and serotonin-1a (5-ht(1a)) receptor system are involved in the pathophysiology of major depression. |
2007-10-23 |
2023-08-12 |
Not clear |
| Elizabeth A Young, Saulo C Ribeiro, Wen Y. Sex differences in ACTH pulsatility following metyrapone blockade in patients with major depression. Psychoneuroendocrinology. vol 32. issue 5. 2007-07-31. PMID:17462829. |
numerous studies suggest that increased central drive to the hypothalamic-pituitary adrenal (hpa) axis occurs in patients with major depression. |
2007-07-31 |
2023-08-12 |
human |
| Charles DeBattista, Joseph Belanoff, Steven Glass, Arif Khan, Robert L Horne, Christine Blasey, Linda L Carpenter, Gustavo Alv. Mifepristone versus placebo in the treatment of psychosis in patients with psychotic major depression. Biological psychiatry. vol 60. issue 12. 2007-01-23. PMID:16889757. |
abnormalities in the hypothalamic pituitary adrenal axis have been implicated in the pathophysiology of psychotic major depression (pmd). |
2007-01-23 |
2023-08-12 |
Not clear |
| Toshiharu Shimazaki, Takao Yoshimizu, Shigeyuki Chak. Melanin-concentrating hormone MCH1 receptor antagonists: a potential new approach to the treatment of depression and anxiety disorders. CNS drugs. vol 20. issue 10. 2007-01-12. PMID:16999451. |
moreover, mch may decrease reward activity while increasing hypothalamus-pituitary adrenal axis activity, both of which may underlie the neurochemical mechanisms of the depression and anxiety-like effects induced by mch. |
2007-01-12 |
2023-08-12 |
Not clear |
| M Kammerer, A Taylor, V Glove. The HPA axis and perinatal depression: a hypothesis. Archives of women's mental health. vol 9. issue 4. 2006-12-07. PMID:16708167. |
levels of all these hormones drop rapidly on parturition.we here suggest that the symptoms of antenatal and postnatal depression may be different, and linked in part with differences in the function of the hypothalamic pituitary adrenal (hpa) axis. |
2006-12-07 |
2023-08-12 |
Not clear |
| Margaret Altemu. Sex differences in depression and anxiety disorders: potential biological determinants. Hormones and behavior. vol 50. issue 4. 2006-11-22. PMID:16920114. |
abnormalities in the regulation of the hypothalamic-pituitary adrenal axis and the sympathoadrenomedullary system have been identified in depression and anxiety disorders, and these disorders are clearly precipitated and exacerbated by stress. |
2006-11-22 |
2023-08-12 |
human |
| Robert T Rubin, Thomas H Miller, Michael E Rhodes, R Kenneth Czambe. Adrenal cortical responses to low- and high-dose ACTH(1-24) administration in major depressives vs. matched controls. Psychiatry research. vol 143. issue 1. 2006-11-09. PMID:16707164. |
these findings do not indicate increased adrenal cortical responsiveness in patients with major depression. |
2006-11-09 |
2023-08-12 |
human |
| Trevor R Norma. Prospects for the treatment of depression. The Australian and New Zealand journal of psychiatry. vol 40. issue 5. 2006-10-26. PMID:16683964. |
compounds based on the hypothalamic pituitary adrenal axis, substance p antagonism and other neuropeptides have potential application for the treatment of depression but require further development before that potential is realized. |
2006-10-26 |
2023-08-12 |
Not clear |
| Glen Davison, Michael Gleeso. The effect of 2 weeks vitamin C supplementation on immunoendocrine responses to 2.5 h cycling exercise in man. European journal of applied physiology. vol 97. issue 4. 2006-09-22. PMID:16685547. |
an increased systemic concentration of stress hormones (of the hypothalamic-pituitary adrenal axis) and some cytokines may contribute to the depression of immune cell function typically observed after prolonged exercise. |
2006-09-22 |
2023-08-12 |
human |
| Timothy G Dinan, Lucinda V Scot. Anatomy of melancholia: focus on hypothalamic-pituitary-adrenal axis overactivity and the role of vasopressin. Journal of anatomy. vol 207. issue 3. 2006-08-21. PMID:16185250. |
overactivity of the hypothalamic-pituitary-adrenal (hpa) axis characterized by hypercortisolism, adrenal hyperplasia and abnormalities in negative feedback is the most consistently described biological abnormality in melancholic depression. |
2006-08-21 |
2023-08-12 |
Not clear |
| Flavia Magri, Luca Cravello, Luca Barili, Serena Sarra, Wilma Cinchetti, Fabrizio Salmoiraghi, Giuliana Micale, Ettore Ferrar. Stress and dementia: the role of the hypothalamicpituitary-adrenal axis. Aging clinical and experimental research. vol 18. issue 2. 2006-07-20. PMID:16702789. |
indeed, adrenal steroids modulate hippocampal plasticity, acting on excitability and long term potentiation or depression. |
2006-07-20 |
2023-08-12 |
human |
| Kai G Kahl, Susanne Bens, Kristin Ziegler, Sebastian Rudolf, Leif Dibbelt, Andreas Kordon, Ulrich Schweige. Cortisol, the cortisol-dehydroepiandrosterone ratio, and pro-inflammatory cytokines in patients with current major depressive disorder comorbid with borderline personality disorder. Biological psychiatry. vol 59. issue 7. 2006-05-09. PMID:16199015. |
major depression in young women is often comorbid with borderline personality disorder (bpd); however, adrenal steroids and pro-inflammatory cytokines in patients with comorbid current major depressive disorder and bpd (mdd/bpd) have not been systematically examined. |
2006-05-09 |
2023-08-12 |
Not clear |
| Maciej Owecki, Izabela Warmuz-Stangierska, Katarzyna Anna Majewska, Elzbieta Nikisch, Jerzy Sowińsk. [Depression and anxiety in patients with adrenal tumor incidentally found on abdominal imaging performed for other indications]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 19. issue 110. 2006-02-23. PMID:16245424. |
[depression and anxiety in patients with adrenal tumor incidentally found on abdominal imaging performed for other indications]. |
2006-02-23 |
2023-08-12 |
Not clear |