| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Baeta-Corral, M De la Fuente, Gimenez-LlortL Giménez-Llor. Sex-dependent worsening of NMDA-induced responses, anxiety, hypercortisolemia, and organometry of early peripheral immunoendocrine impairment in adult 3xTg-AD mice and their long-lasting ontogenic modulation by neonatal handling. Behavioural brain research. 2022-11-07. PMID:36343697. |
the behavioral patterns elicited by the direct exposure to an open field, and the motor depression response evoked by nmda (25mg/kg, i.p) were found correlated to the organometry of peripheral immune-endocrine organs (thymus involution, splenomegaly, and adrenal glands' hypertrophy) and increased corticosterone levels, suggesting their potential value for diagnostic and biomonitoring.the nmda-induced immediate and depressant motor activity and endocrine (corticosterone) responses were sensitive to sex and ad-genotype, suggesting worse endogenous susceptibility/neuroprotective response to glutamatergic excitotoxicity in males and in the ad-genotype. |
2022-11-07 |
2023-08-14 |
mouse |
| Catherine B Stroud, Frances R Chen, Rachel Y Levin, Morgan M Richman, Erin Lamberth, Leah D Doan. Individual differences in latent trait cortisol (LTC): Implications for the onset and course of future depressive symptoms. Psychoneuroendocrinology. vol 146. 2022-09-27. PMID:36155317. |
research suggests that various indicators of hypothalamic pituitary adrenal (hpa) axis activity prospectively predict depression, but few studies have evaluated whether trait indicators of hpa axis activity are related to depression. |
2022-09-27 |
2023-08-14 |
Not clear |
| Raphael Hirtz, Lars Libuda, Anke Hinney, Manuel Föcker, Judith Bühlmeier, Paul-Martin Holterhus, Alexandra Kulle, Cordula Kiewert, Berthold P Hauffa, Johannes Hebebrand, Corinna Graseman. The adrenal steroid profile in adolescent depression: a valuable bio-readout? Translational psychiatry. vol 12. issue 1. 2022-06-18. PMID:35717450. |
the adrenal steroid profile in adolescent depression: a valuable bio-readout? |
2022-06-18 |
2023-08-14 |
Not clear |
| Amalia Dávila-Hernández, Roberto González-González, Sonia Guzmán-Velázquez, Olivia Tania Hernández Hernández, Sergio R Zamudio, Lucía Martínez-Mot. Antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal BDNF expression in male rats. Brain research bulletin. vol 173. 2021-12-09. PMID:33991609. |
post-weaning social isolated rodents exhibit pathophysiological changes associated with depression including adrenal axis hyperactivity, gonadal hormone level disturbances, molecular alterations in hippocampus, and immobility behavior in the forced swimming test (fst). |
2021-12-09 |
2023-08-13 |
rat |
| Long Chen, Xiaokun Wang, Yunpeng Zhang, Hequan Zhong, Cuiting Wang, Pengfei Gao, Bing L. Daidzein Alleviates Hypothalamic-Pituitary-Adrenal Axis Hyperactivity, Ameliorates Depression-Like Behavior, and Partly Rectifies Circulating Cytokine Imbalance in Two Rodent Models of Depression. Frontiers in behavioral neuroscience. vol 15. 2021-11-05. PMID:34733143. |
recent studies have provided strong evidence that depression may be accompanied by immune activation, secondary inflammatory reaction, and hyperactivity of the hypothalamic pituitary adrenal (hpa) axis. |
2021-11-05 |
2023-08-13 |
Not clear |
| Briana Nc Chronister, Eduardo Gonzalez, Dolores Lopez-Paredes, Jose Suarez-Torres, Sheila Gahagan, Danilo Martinez, Janeth Barros, David R Jacobs, Harvey Checkoway, Jose R Suarez-Lope. Testosterone, estradiol, DHEA and cortisol in relation to anxiety and depression scores in adolescents. Journal of affective disorders. vol 294. 2021-10-29. PMID:34375211. |
background adrenal and sex hormone dysregulation have been independently associated with increased depression and anxiety. |
2021-10-29 |
2023-08-13 |
human |
| Briana Nc Chronister, Eduardo Gonzalez, Dolores Lopez-Paredes, Jose Suarez-Torres, Sheila Gahagan, Danilo Martinez, Janeth Barros, David R Jacobs, Harvey Checkoway, Jose R Suarez-Lope. Testosterone, estradiol, DHEA and cortisol in relation to anxiety and depression scores in adolescents. Journal of affective disorders. vol 294. 2021-10-29. PMID:34375211. |
this study evaluated associations and interplay of sex and adrenal hormones with depression and anxiety. |
2021-10-29 |
2023-08-13 |
human |
| Aarthi Ethirajulu, Almothana Alkasabera, Chike B Onyali, Comfort Anim-Koranteng, Hira E Shah, Nitin Bhawnani, Jihan A Mostaf. Insulin Resistance, Hyperandrogenism, and Its Associated Symptoms Are the Precipitating Factors for Depression in Women With Polycystic Ovarian Syndrome. Cureus. vol 13. issue 9. 2021-10-22. PMID:34667688. |
the various pathophysiological mechanisms that lead to depression are insulin resistance, disturbance in the hypothalamic pituitary adrenal (hpa) axis, hyperandrogenism and its clinical presentation, obesity, and infertility. |
2021-10-22 |
2023-08-13 |
Not clear |
| Tanveer Singh, Rajesh Kumar Goe. Epilepsy Associated Depression: An Update on Current Scenario, Suggested Mechanisms, and Opportunities. Neurochemical research. vol 46. issue 6. 2021-10-12. PMID:33665775. |
we should also move beyond ads, and therefore, we reviewed common pathological mechanisms such as neuroinflammation, dysregulated hypothalamus pituitary adrenal (hpa) axis, altered neurogenesis, and altered tryptophan metabolism responsible for coexistent relationship of epilepsy and depression. |
2021-10-12 |
2023-08-13 |
Not clear |
| Marie-Claude Mokrani, Fabrice Duval, Alexis Erb, Felix Gonzalez Lopera, Vlad Danil. Are the thyroid and adrenal system alterations linked in depression? Psychoneuroendocrinology. vol 122. 2021-08-30. PMID:33068950. |
are the thyroid and adrenal system alterations linked in depression? |
2021-08-30 |
2023-08-13 |
Not clear |
| b' A S \\xc5\\xa0ojat, B Dunji\\xc4\\x87-Kosti\\xc4\\x87, L V Marina, M Ivovi\\xc4\\x87, N V Radonji\\xc4\\x87, A Kendere\\xc5\\xa1ki, A \\xc4\\x86irkovi\\xc4\\x87, M Tan\\xc4\\x8di\\xc4\\x87-Gaji\\xc4\\x87, Z Arizanovi\\xc4\\x87, S Mihajlovi\\xc4\\x87, S Vujovi\\xc4\\x8. Depression: another cortisol-related comorbidity in patients with adrenal incidentalomas and (possible) autonomous cortisol secretion. Journal of endocrinological investigation. vol 44. issue 9. 2021-08-12. PMID:33528757.' |
depression: another cortisol-related comorbidity in patients with adrenal incidentalomas and (possible) autonomous cortisol secretion. |
2021-08-12 |
2023-08-13 |
Not clear |
| b' A S \\xc5\\xa0ojat, B Dunji\\xc4\\x87-Kosti\\xc4\\x87, L V Marina, M Ivovi\\xc4\\x87, N V Radonji\\xc4\\x87, A Kendere\\xc5\\xa1ki, A \\xc4\\x86irkovi\\xc4\\x87, M Tan\\xc4\\x8di\\xc4\\x87-Gaji\\xc4\\x87, Z Arizanovi\\xc4\\x87, S Mihajlovi\\xc4\\x87, S Vujovi\\xc4\\x8. Depression: another cortisol-related comorbidity in patients with adrenal incidentalomas and (possible) autonomous cortisol secretion. Journal of endocrinological investigation. vol 44. issue 9. 2021-08-12. PMID:33528757.' |
according to the available literature, studies examining the depression risk in patients with adrenal incidentalomas (ai), nonfunctioning and the ones with (possible) autonomous cortisol secretion ((p)acs) are scarce. |
2021-08-12 |
2023-08-13 |
Not clear |
| b' A S \\xc5\\xa0ojat, B Dunji\\xc4\\x87-Kosti\\xc4\\x87, L V Marina, M Ivovi\\xc4\\x87, N V Radonji\\xc4\\x87, A Kendere\\xc5\\xa1ki, A \\xc4\\x86irkovi\\xc4\\x87, M Tan\\xc4\\x8di\\xc4\\x87-Gaji\\xc4\\x87, Z Arizanovi\\xc4\\x87, S Mihajlovi\\xc4\\x87, S Vujovi\\xc4\\x8. Depression: another cortisol-related comorbidity in patients with adrenal incidentalomas and (possible) autonomous cortisol secretion. Journal of endocrinological investigation. vol 44. issue 9. 2021-08-12. PMID:33528757.' |
the aim of this observational, case-control study was to screen patients with nonfunctioning adrenal incidentalomas (nai) and the ones with (p)acs for depression and to assess their qol. |
2021-08-12 |
2023-08-13 |
Not clear |
| Ronald B Brow. Stress, inflammation, depression, and dementia associated with phosphate toxicity. Molecular biology reports. vol 47. issue 12. 2021-07-12. PMID:33226563. |
in a reciprocal interaction, phosphate toxicity is capable of harming adrenal gland function, possibly leading to adrenal insufficiency and depression. |
2021-07-12 |
2023-08-13 |
Not clear |
| Jose R Suarez-Lopez, Andrew Nguyen, Joel Klas, Sheila Gahagan, Harvey Checkoway, Dolores Lopez-Paredes, Madison Nobl. Associations of acetylcholinesterase inhibition between pesticide spray seasons with depression and anxiety symptoms in adolescents, and the role of sex and adrenal hormones on gender moderation. Exposure and health. vol 13. issue 1. 2021-03-24. PMID:33748533. |
associations of acetylcholinesterase inhibition between pesticide spray seasons with depression and anxiety symptoms in adolescents, and the role of sex and adrenal hormones on gender moderation. |
2021-03-24 |
2023-08-13 |
Not clear |
| Birsen Şentürk Pilan, Burcu Özbaran, Didem Çelik, Tuğçe Özcan, Samim Özen, Damla Gökşen, İbrahim Ulman, Ali Avanoğlu, Sibel Tiryaki, Hüseyin Onay, Özgür Çoğulu, Ferda Özkınay, Şükran Darca. Psychiatric view for disorders of sex development: a 12-year experience of a multidisciplinary team in a university hospital. Journal of pediatric endocrinology & metabolism : JPEM. vol 33. issue 5. 2021-03-22. PMID:32238607. |
adhd was most common in congenital adrenal hyperplasia (n = 4, 22.4%) and androgen synthesis defects (asd) (n = 4, 22.4%); depression was most common in complete gonadal dysgenesis and asd (n = 3, 23.1%); and mental retardation was most common in asd (n = 3, 37.5%). |
2021-03-22 |
2023-08-13 |
Not clear |
| Kyoko Konishi, Sara Cherkerzian, Emily G Jacobs, Christine Richards, Anne Remington, Harlyn Aizley, Madhusmita Misra, Bill L Lasley, Jill M Goldstei. Impact of adrenal hormones, reproductive aging, and major depression on memory circuitry decline in early midlife. Brain research. vol 1721. 2020-10-01. PMID:31279842. |
impact of adrenal hormones, reproductive aging, and major depression on memory circuitry decline in early midlife. |
2020-10-01 |
2023-08-13 |
human |
| Andrei Costache, Anca-Lelia Riza, Mihai Ioana, Daniela Gabriela Glavan, Mihaela-Eugenia Dinca, Ionela-Mihaela Vladu, Mihaela Popescu, Ion Udristoi. Circulating Cortisol in a Cohort of Depressive Patients. Current health sciences journal. vol 46. issue 1. 2020-09-28. PMID:32637160. |
it has long been suspected that the hypothalamic pituitary adrenal (hpa) axis plays a role in the pathophysiology of depression. |
2020-09-28 |
2023-08-13 |
human |
| Jianguo Li, Jing Chen, Na Ma, Deping Yan, Ying Wang, Xin Zhao, Yu Zhang, Ce Zhan. Effects of corticosterone on the expression of mature brain-derived neurotrophic factor (mBDNF) and proBDNF in the hippocampal dentate gyrus. Behavioural brain research. vol 365. 2020-03-09. PMID:30851317. |
chronic stressor induces the release of glucocorticoid from the adrenal glands, the subsequent decrease of hippocampal volume, and the development of depression. |
2020-03-09 |
2023-08-13 |
rat |
| Ajeet Kumar, Shalini Dogra, Chandan Sona, Deepmala Umrao, Mamunur Rashid, Sandeep K Singh, Muhammad Wahajuddin, Prem N Yada. Chronic histamine 3 receptor antagonism alleviates depression like conditions in mice via modulation of brain-derived neurotrophic factor and hypothalamus-pituitary adrenal axis. Psychoneuroendocrinology. vol 101. 2020-03-03. PMID:30458370. |
chronic histamine 3 receptor antagonism alleviates depression like conditions in mice via modulation of brain-derived neurotrophic factor and hypothalamus-pituitary adrenal axis. |
2020-03-03 |
2023-08-13 |
mouse |