| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bartley G Hoebel, Nicole M Avena, Pedro Rad. Accumbens dopamine-acetylcholine balance in approach and avoidance. Current opinion in pharmacology. vol 7. issue 6. 2008-01-24. PMID:18023617. |
research on the neural organization and functions of the dorsal striatum in movement disorders, such as huntington's and parkinson's disease, can inform the study of the nucleus accumbens (nac) in motivational disorders, such as addiction and depression. |
2008-01-24 |
2023-08-12 |
Not clear |
| O Malkesman, M Shayit, R Genud, A Zangen, N Kinor, R Maayan, A Weizman, A Weller, G Yadi. Dehydroepiandrosterone in the nucleus accumbens is associated with early onset of depressive-behavior: a study in an animal model of childhood depression. Neuroscience. vol 149. issue 3. 2008-01-16. PMID:17919828. |
dehydroepiandrosterone in the nucleus accumbens is associated with early onset of depressive-behavior: a study in an animal model of childhood depression. |
2008-01-16 |
2023-08-12 |
rat |
| Elizabeth Silva, Luis Hernánde. [Extracellular aminoacids in the amygdala and nucleus accumbens in the rat during acute pain]. Investigacion clinica. vol 48. issue 2. 2007-08-30. PMID:17598644. |
these experiments suggest that rapid neurotransmitters changes observed in the nucleus accumbens and amygdala, are possibly related to immobility and emotional states such as anxiety, aversion and/or depression caused by pain. |
2007-08-30 |
2023-08-12 |
rat |
| Lucyna Antkiewicz-Michaluk, Jerzy Michaluk, Irena Romańska, Piotr Popik, Martyna Krawczyk, Irena Nalepa, Jerzy Vetulan. Nicotine potentiates imipramine-induced effects on catecholamine metabolism: possible relation to antidepressant activity. Pharmacological reports : PR. vol 58. issue 6. 2007-05-11. PMID:17220541. |
as revealed by hplc, dopamine metabolism in the nucleus accumbens was slightly decreased after 14 days of treatment with imipramine, and co-administration of nicotine resulted in a significant and much more pronounced depression of dopamine metabolism in all investigated dopaminergic structures. |
2007-05-11 |
2023-08-12 |
rat |
| W C Matowe, K V V Ananthalakshmi, S B Kombia. Role of protein kinase C in substance P-induced synaptic depression in the nucleus accumbens in vitro. Medical principles and practice : international journal of the Kuwait University, Health Science Centre. vol 16. issue 2. 2007-04-03. PMID:17303942. |
role of protein kinase c in substance p-induced synaptic depression in the nucleus accumbens in vitro. |
2007-04-03 |
2023-08-12 |
Not clear |
| W C Matowe, K V V Ananthalakshmi, S B Kombia. Role of protein kinase C in substance P-induced synaptic depression in the nucleus accumbens in vitro. Medical principles and practice : international journal of the Kuwait University, Health Science Centre. vol 16. issue 2. 2007-04-03. PMID:17303942. |
this study set out to determine the roles of protein kinase a (pka) and protein kinase c (pkc) signalling cascades in substance p- (sp-) mediated synaptic depression in the nucleus accumbens. |
2007-04-03 |
2023-08-12 |
Not clear |
| P Rada, C Colasante, M Skirzewski, L Hernandez, B Hoebe. Behavioral depression in the swim test causes a biphasic, long-lasting change in accumbens acetylcholine release, with partial compensation by acetylcholinesterase and muscarinic-1 receptors. Neuroscience. vol 141. issue 1. 2006-09-28. PMID:16677771. |
the nucleus accumbens may play a role in acquisition and expression of behavioral depression as measured using the inescapable swim test. |
2006-09-28 |
2023-08-12 |
rat |
| Eric J Nestler, William A Carlezo. The mesolimbic dopamine reward circuit in depression. Biological psychiatry. vol 59. issue 12. 2006-09-07. PMID:16566899. |
here we focus on the potential role of the nucleus accumbens (nac; ventral striatum) and its dopaminergic input from the ventral tegmental area (vta), which form the mesolimbic dopamine system, in depression. |
2006-09-07 |
2023-08-12 |
Not clear |
| Jun-ichi Karasawa, Takao Yoshimizu, Shigeyuki Chak. A metabotropic glutamate 2/3 receptor antagonist, MGS0039, increases extracellular dopamine levels in the nucleus accumbens shell. Neuroscience letters. vol 393. issue 2-3. 2006-03-14. PMID:16233956. |
in the present study, we examined the effect of mgs0039 on extracellular dopamine levels in the rat nucleus accumbens (nac) shell using in vivo microdialysis evaluation because accumbal dopamine has been implicated in depression. |
2006-03-14 |
2023-08-12 |
rat |
| K J Gill, A E Boyl. Genetic basis for the psychostimulant effects of nicotine: a quantitative trait locus analysis in AcB/BcA recombinant congenic mice. Genes, brain, and behavior. vol 4. issue 7. 2006-01-23. PMID:16176386. |
single-locus association analysis in the acb rcs identified quantitative trait loci (qtl) for the psychostimulant effects of nicotine on chromosomes 11, 12, 13, 14 and 17 and one qtl for nicotine-induced depression on chromosome 11. |
2006-01-23 |
2023-08-12 |
mouse |
| L Yavich, A Yline. Spreading depression in the cortex differently modulates dopamine release in rat mesolimbic and nigrostriatal terminal fields. Experimental neurology. vol 196. issue 1. 2005-11-22. PMID:16084513. |
the effects of cortical spreading depression (sd) on evoked dopamine release in mesolimbic (nucleus accumbens) and nigrostriatal (nucleus caudatus) terminal fields were studied by in vivo voltammetry in anesthetized rats. |
2005-11-22 |
2023-08-12 |
human |
| L Yavich, A Yline. Spreading depression in the cortex differently modulates dopamine release in rat mesolimbic and nigrostriatal terminal fields. Experimental neurology. vol 196. issue 1. 2005-11-22. PMID:16084513. |
this cortical depression increased stimulated dopamine release in the nucleus accumbens and decreased dopamine release in the nucleus caudatus. |
2005-11-22 |
2023-08-12 |
human |
| L Yavich, A Yline. Spreading depression in the cortex differently modulates dopamine release in rat mesolimbic and nigrostriatal terminal fields. Experimental neurology. vol 196. issue 1. 2005-11-22. PMID:16084513. |
it is proposed that depression and activation of evoked dopamine release in the nucleus caudatus and nucleus accumbens following sd are indicative of tonic activation of the nigrostriatal and tonic inhibition of the mesolimbic dopaminergic terminals by cortex in normal conditions. |
2005-11-22 |
2023-08-12 |
human |
| Mark J Hunt, Karima Kessal, Rene Garci. Ketamine induces dopamine-dependent depression of evoked hippocampal activity in the nucleus accumbens in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 2. 2005-08-17. PMID:15647498. |
ketamine induces dopamine-dependent depression of evoked hippocampal activity in the nucleus accumbens in freely moving rats. |
2005-08-17 |
2023-08-12 |
rat |
| Mark J Hunt, Karima Kessal, Rene Garci. Ketamine induces dopamine-dependent depression of evoked hippocampal activity in the nucleus accumbens in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 2. 2005-08-17. PMID:15647498. |
notably, the depression of field potentials recorded in the nucleus accumbens was markedly reduced after a focal 6-hydroxydopamine lesioning procedure in the nucleus accumbens. |
2005-08-17 |
2023-08-12 |
rat |
| Mark J Hunt, Karima Kessal, Rene Garci. Ketamine induces dopamine-dependent depression of evoked hippocampal activity in the nucleus accumbens in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 2. 2005-08-17. PMID:15647498. |
more specifically, pretreatment with the d2/d4 antagonist haloperidol, but not the d1 antagonist sch23390 blocked ketamine-induced depression of nucleus accumbens responses. |
2005-08-17 |
2023-08-12 |
rat |
| Robert H Paul, Adam M Brickman, Bradford Navia, Charles Hinkin, Paul F Malloy, Angela L Jefferson, Ronald A Cohen, David F Tate, Timothy P Flaniga. Apathy is associated with volume of the nucleus accumbens in patients infected with HIV. The Journal of neuropsychiatry and clinical neurosciences. vol 17. issue 2. 2005-06-27. PMID:15939969. |
by contrast, ratings of depression were unrelated to either apathy or nucleus accumbens volume. |
2005-06-27 |
2023-08-12 |
human |
| Eliyahu Dremencov, Michael E Newman, Noa Kinor, Gitit Blatman-Jan, Cheryl J Schindler, David H Overstreet, Gal Yadi. Hyperfunctionality of serotonin-2C receptor-mediated inhibition of accumbal dopamine release in an animal model of depression is reversed by antidepressant treatment. Neuropharmacology. vol 48. issue 1. 2005-04-28. PMID:15617725. |
dopamine release in the nucleus accumbens mediates motivation and reward, making it a likely candidate to be involved in anhedonia, one of the major symptoms of depression. |
2005-04-28 |
2023-08-12 |
rat |
| D F Avgustinovich, O V Alekseenko, I V Bakshtanovskaia, L A Koriakina, T V Lipina, M V Tenditnik, N P Bondar', I L Kovalenko, N N Kudriavtsev. [Dynamic changes of brain serotonergic and dopaminergic activities during development of anxious depression: experimental study]. Uspekhi fiziologicheskikh nauk. vol 35. issue 4. 2005-03-31. PMID:15573884. |
decreased 5-hiaa levels in the hippocampus, amygdala and nucleus accumbens were discovered at the stage of forming depression (10 days of social stress). |
2005-03-31 |
2023-08-12 |
mouse |
| David W Self, Kwang-Ho Choi, Diana Simmons, John R Walker, Cynthia S Smagul. Extinction training regulates neuroadaptive responses to withdrawal from chronic cocaine self-administration. Learning & memory (Cold Spring Harbor, N.Y.). vol 11. issue 5. 2005-01-06. PMID:15466321. |
extinction training normalizes tyrosine hydroxylase levels in the nucleus accumbens (nac) shell, an effect that could help ameliorate dysphoria and depression associated with withdrawal from chronic cocaine use. |
2005-01-06 |
2023-08-12 |
rat |