Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K Mahati, V Bhagya, T Christofer, A Sneha, B S Shankaranarayana Ra. Enriched environment ameliorates depression-induced cognitive deficits and restores abnormal hippocampal synaptic plasticity. Neurobiology of learning and memory. vol 134 Pt B. 2018-02-09. PMID:27555234. |
severe depression compromises structural and functional integrity of the brain and results in impaired learning and memory, maladaptive synaptic plasticity as well as degenerative changes in the hippocampus and amygdala. |
2018-02-09 |
2023-08-13 |
rat |
R Kimura, D MacTavish, J Yang, D Westaway, Jack H Jhamanda. Pramlintide Antagonizes Beta Amyloid (Aβ)- and Human Amylin-Induced Depression of Hippocampal Long-Term Potentiation. Molecular neurobiology. vol 54. issue 1. 2018-02-08. PMID:26768593. |
pramlintide antagonizes beta amyloid (aβ)- and human amylin-induced depression of hippocampal long-term potentiation. |
2018-02-08 |
2023-08-13 |
mouse |
Rieko Watanabe, Shingo Kakeda, Keita Watanabe, Xiaodan Liu, Asuka Katsuki, Wakako Umeno-Nakano, Hikaru Hori, Osamu Abe, Reiji Yoshimura, Yukunori Korog. Relationship between the hippocampal shape abnormality and serum cortisol levels in first-episode and drug-naïve major depressive disorder patients. Depression and anxiety. vol 34. issue 5. 2018-02-06. PMID:28129464. |
we aimed to investigate the relationship between the hippocampal shape deformations and the serum cortisol levels in first-episode and drug-naïve major depression disorder (mdd) patients. |
2018-02-06 |
2023-08-13 |
Not clear |
Niels R Reinders, Yvonne Pao, Maria C Renner, Carla M da Silva-Matos, Tessa R Lodder, Roberto Malinow, Helmut W Kessel. Amyloid-β effects on synapses and memory require AMPA receptor subunit GluA3. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 42. 2018-01-30. PMID:27708157. |
hippocampal neurons that lack glua3 were resistant against aβ-mediated synaptic depression and spine loss. |
2018-01-30 |
2023-08-13 |
mouse |
Bojana Stefanovic, Natasa Spasojevic, Predrag Jovanovic, Nebojsa Jasnic, Jelena Djordjevic, Sladjana Dronja. Melatonin mediated antidepressant-like effect in the hippocampus of chronic stress-induced depression rats: Regulating vesicular monoamine transporter 2 and monoamine oxidase A levels. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 10. 2018-01-29. PMID:27499503. |
melatonin mediated antidepressant-like effect in the hippocampus of chronic stress-induced depression rats: regulating vesicular monoamine transporter 2 and monoamine oxidase a levels. |
2018-01-29 |
2023-08-13 |
rat |
Emma L Elcombe, Jim Lagopoulos, Loren Mowszowski, Keri Diamond, Matthew Paradise, Ian B Hickie, Simon J G Lewis, Sharon L Naismit. Clinical and Cognitive Correlates of Structural Hippocampal Change in "At-Risk" Older Adults. Journal of geriatric psychiatry and neurology. vol 27. issue 2. 2018-01-26. PMID:24196661. |
conversely, depression and disability were associated with decreases in hippocampal volume. |
2018-01-26 |
2023-08-12 |
Not clear |
Emma L Elcombe, Jim Lagopoulos, Loren Mowszowski, Keri Diamond, Matthew Paradise, Ian B Hickie, Simon J G Lewis, Sharon L Naismit. Clinical and Cognitive Correlates of Structural Hippocampal Change in "At-Risk" Older Adults. Journal of geriatric psychiatry and neurology. vol 27. issue 2. 2018-01-26. PMID:24196661. |
these findings suggest that factors associated with cognitive reserve, cognition and depression may play an integral pathophysiological role in determining hippocampal volumes in "at-risk" older adults. |
2018-01-26 |
2023-08-12 |
Not clear |
Aldo Córdova-Palomera, Marcel A de Reus, Mar Fatjó-Vilas, Carles Falcón, Nuria Bargalló, Martijn P van den Heuvel, Lourdes Fañaná. FKBP5 modulates the hippocampal connectivity deficits in depression: a study in twins. Brain imaging and behavior. vol 11. issue 1. 2018-01-25. PMID:26801675. |
fkbp5 modulates the hippocampal connectivity deficits in depression: a study in twins. |
2018-01-25 |
2023-08-13 |
Not clear |
Aldo Córdova-Palomera, Marcel A de Reus, Mar Fatjó-Vilas, Carles Falcón, Nuria Bargalló, Martijn P van den Heuvel, Lourdes Fañaná. FKBP5 modulates the hippocampal connectivity deficits in depression: a study in twins. Brain imaging and behavior. vol 11. issue 1. 2018-01-25. PMID:26801675. |
the putative genetic or environmental roots of the association between depression and structural connectivity alterations of the hippocampus were evaluated combining diffusion weighted imaging with both a quantitative genetics approach and molecular information on the rs1360780 single nucleotide polymorphism, in a sample of 54 informative monozygotic twins (27 pairs). |
2018-01-25 |
2023-08-13 |
Not clear |
Aldo Córdova-Palomera, Marcel A de Reus, Mar Fatjó-Vilas, Carles Falcón, Nuria Bargalló, Martijn P van den Heuvel, Lourdes Fañaná. FKBP5 modulates the hippocampal connectivity deficits in depression: a study in twins. Brain imaging and behavior. vol 11. issue 1. 2018-01-25. PMID:26801675. |
first, graph-theoretical measures of hippocampal connectivity were altered in depression. |
2018-01-25 |
2023-08-13 |
Not clear |
Aldo Córdova-Palomera, Marcel A de Reus, Mar Fatjó-Vilas, Carles Falcón, Nuria Bargalló, Martijn P van den Heuvel, Lourdes Fañaná. FKBP5 modulates the hippocampal connectivity deficits in depression: a study in twins. Brain imaging and behavior. vol 11. issue 1. 2018-01-25. PMID:26801675. |
third, there is an additive interaction effect between fkbp5's rs1360780 variant and the graph-theoretical metrics of hippocampal connectivity to influence depression risk. |
2018-01-25 |
2023-08-13 |
Not clear |
Ke Cheng, Juan Li, Deyu Yang, Yongtao Yang, Chenglong Rao, Shuxiao Zhang, Wei Wang, Hua Guo, Liang Fang, Dan Zhu, Yu Han, Peng Xi. 2D-gel based proteomics unravels neurogenesis and energetic metabolism dysfunction of the olfactory bulb in CUMS rat model. Behavioural brain research. vol 313. 2018-01-25. PMID:27340088. |
we previously interrogated the mechanism of decreasing hippocampus neurogenesis in cums rat model of depression. |
2018-01-25 |
2023-08-13 |
rat |
T Wise, J Radua, E Via, N Cardoner, O Abe, T M Adams, F Amico, Y Cheng, J H Cole, C de Azevedo Marques Périco, D P Dickstein, T F D Farrow, T Frodl, G Wagner, I H Gotlib, O Gruber, B J Ham, D E Job, M J Kempton, M J Kim, P C M P Koolschijn, G S Malhi, D Mataix-Cols, A M McIntosh, A C Nugent, J T O'Brien, S Pezzoli, M L Phillips, P S Sachdev, G Salvadore, S Selvaraj, A C Stanfield, A J Thomas, M J van Tol, N J A van der Wee, D J Veltman, A H Young, C H Fu, A J Cleare, D Arnon. Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis. Molecular psychiatry. vol 22. issue 10. 2018-01-19. PMID:27217146. |
group comparisons indicated that findings of smaller grey-matter volumes relative to controls in the right dorsolateral prefrontal cortex and left hippocampus, along with cerebellar, temporal and parietal regions were more substantial in major depression. |
2018-01-19 |
2023-08-13 |
Not clear |
Vera Chesnokova, Robert N Pechnick, Kolja Wawrowsk. Chronic peripheral inflammation, hippocampal neurogenesis, and behavior. Brain, behavior, and immunity. vol 58. 2018-01-17. PMID:26802985. |
adult hippocampal neurogenesis is involved in memory and learning, and disrupted neurogenesis is implicated in cognitive impairment and mood disorders, including anxiety and depression. |
2018-01-17 |
2023-08-13 |
human |
Vera Chesnokova, Robert N Pechnick, Kolja Wawrowsk. Chronic peripheral inflammation, hippocampal neurogenesis, and behavior. Brain, behavior, and immunity. vol 58. 2018-01-17. PMID:26802985. |
these conditions are associated with behavioral disturbances linked to disrupted adult hippocampal neurogenesis, such as cognitive impairment, deficits in learning and memory, and depression and anxiety. |
2018-01-17 |
2023-08-13 |
human |
Tobias Buchborn, Helmut Schröder, Volker Höllt, Gisela Grecksc. Repeated lysergic acid diethylamide in an animal model of depression: Normalisation of learning behaviour and hippocampal serotonin 5-HT2 signalling. Journal of psychopharmacology (Oxford, England). vol 28. issue 6. 2018-01-16. PMID:24785760. |
repeated lysergic acid diethylamide in an animal model of depression: normalisation of learning behaviour and hippocampal serotonin 5-ht2 signalling. |
2018-01-16 |
2023-08-13 |
rat |
Junghee Jin, Seung-Nam Kim, Xuqing Liu, Haijun Zhang, Chao Zhang, Ji-Seon Seo, Yong Kim, Tao Su. miR-17-92 Cluster Regulates Adult Hippocampal Neurogenesis, Anxiety, and Depression. Cell reports. vol 16. issue 6. 2018-01-16. PMID:27477270. |
mir-17-92 cluster regulates adult hippocampal neurogenesis, anxiety, and depression. |
2018-01-16 |
2023-08-13 |
mouse |
Liang Liu, Qin Zhang, Yulong Cai, Dayu Sun, Xie He, Lian Wang, Dan Yu, Xin Li, Xiaoyi Xiong, Haiwei Xu, Qingwu Yang, Xiaotang Fa. Resveratrol counteracts lipopolysaccharide-induced depressive-like behaviors via enhanced hippocampal neurogenesis. Oncotarget. vol 7. issue 35. 2018-01-16. PMID:27517628. |
radial glial-like cells (rgls) in the adult dentate gyrus (dg) function as progenitor cells for adult hippocampal neurogenesis, a process involved in the stress-related pathophysiology and treatment efficiency of depression. |
2018-01-16 |
2023-08-13 |
mouse |
Yuki Tomiga, Saki Yoshimura, Ai Ito, Shihoko Nakashima, Kentaro Kawanaka, Yoshinari Uehara, Hiroaki Tanaka, Yasuki Higak. Exercise training rescues high fat diet-induced neuronal nitric oxide synthase expression in the hippocampus and cerebral cortex of mice. Nitric oxide : biology and chemistry. vol 66. 2018-01-16. PMID:28302517. |
our results suggest that hfd-induced brain dysfunction may be regulated by hippocampal and/or cortical nnos, and that exercise may have therapeutic potential for the treatment of hfd-induced depression and anxiety via the nnos/no pathway. |
2018-01-16 |
2023-08-13 |
mouse |
I G Silkis, V A Makechi. Possible Mechanisms of Influence of Various Concentrations of Acetylcholine on Hippocampal Functioning. Uspekhi fiziologicheskikh nauk. vol 47. issue 4. 2018-01-16. PMID:29283235. |
it follows from the proposed mechanism that a lowing concentration of acetylcholine in the hippocampus, a decrease in density of М1/ М3 and a4p2 receptors, and augmenting binding of М2 receptors must lead to a depression of responses of pyramidal neurons in СА3 and СА1 fields to signals from the entorhinal cortex. |
2018-01-16 |
2023-08-13 |
Not clear |