| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Johanna Steinke, Christian Gaser, Kerstin Langbein, Maren Dietzek, Alexander Gussew, J\\xc3\\xbcrgen R Reichenbach, Stefan Smesny, Heinrich Sauer, Igor Nenadi\\xc4\\x8. Hippocampal metabolism and prefrontal brain structure: A combined 1H-MR spectroscopy, neuropsychological, and voxel-based morphometry (VBM) study. Brain research. vol 1677. 2018-06-11. PMID:28899759.' |
our studies demonstrate a structure-function correlation that might underlie the interaction of the hippocampus with prefrontal cortex and cerebellum, which might be central to several neurological and psychiatric disorders, including schizophrenia or depression. |
2018-06-11 |
2023-08-13 |
human |
| Ming-Ming Tang, Wen-Juan Lin, Jun-Tao Zhang, Ya-Wei Zhao, Ying-Cong L. Exogenous FGF2 reverses depressive-like behaviors and restores the suppressed FGF2-ERK1/2 signaling and the impaired hippocampal neurogenesis induced by neuroinflammation. Brain, behavior, and immunity. vol 66. 2018-06-06. PMID:28529071. |
these findings suggest that hippocampal neurogenesis might be one of biological mechanisms underlying depression induced by neuroinflammation and targeting neurogenesis might lead to new therapeutic strategies for the treatment of depression. |
2018-06-06 |
2023-08-13 |
rat |
| Ming-Ming Tang, Wen-Juan Lin, Jun-Tao Zhang, Ya-Wei Zhao, Ying-Cong L. Exogenous FGF2 reverses depressive-like behaviors and restores the suppressed FGF2-ERK1/2 signaling and the impaired hippocampal neurogenesis induced by neuroinflammation. Brain, behavior, and immunity. vol 66. 2018-06-06. PMID:28529071. |
in this study, we manipulated adult hippocampal neurogenesis using fibroblast growth factor 2 (fgf2), one crucial molecule modulating cell proliferation and survival in central nervous system, and investigate the involvement and the potential therapeutic effects of fgf2 on neuroinflammation-induced depression. |
2018-06-06 |
2023-08-13 |
rat |
| Jinqiang Zhang, Xiaofang Xie, Mingming Tang, Jing Zhang, Boyang Zhang, Qiuying Zhao, Yue Han, Wan Yan, Cheng Peng, Zili Yo. Salvianolic acid B promotes microglial M2-polarization and rescues neurogenesis in stress-exposed mice. Brain, behavior, and immunity. vol 66. 2018-06-06. PMID:28736034. |
these findings suggest a possible antidepressive mechanism for anti-inflammatory agents that is correlated with microglial polarization and hippocampal neurogenesis and which may provide a new microglia-targeted strategy for depression therapy. |
2018-06-06 |
2023-08-13 |
mouse |
| Ho-Hyun Seong, Jong-Min Park, Youn-Jung Ki. Antidepressive Effects of Environmental Enrichment in Chronic Stress-Induced Depression in Rats. Biological research for nursing. vol 20. issue 1. 2018-06-04. PMID:28931312. |
chronic stress-induced depression has detrimental effects on hippocampal integrity. |
2018-06-04 |
2023-08-13 |
rat |
| Giulia Ida Perini, Tommaso Toffanin, Giorgio Pigato, Giovanni Ferri, Halima Follador, Filippo Zonta, Carlo Pastorelli, Giulia Piazzon, Luca Denaro, Giuseppe Rolma, Mario Ermani, Domenico DʼAvell. Hippocampal Gray Volumes Increase in Treatment-Resistant Depression Responding to Vagus Nerve Stimulation. The journal of ECT. vol 33. issue 3. 2018-05-30. PMID:28658013. |
hippocampal gray volumes increase in treatment-resistant depression responding to vagus nerve stimulation. |
2018-05-30 |
2023-08-13 |
Not clear |
| Johan-Till Pougnet, Benjamin Compans, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabo. P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons. Scientific reports. vol 6. 2018-05-22. PMID:27624155. |
p2x-mediated ampa receptor internalization and synaptic depression is controlled by two camkii phosphorylation sites on glua1 in hippocampal neurons. |
2018-05-22 |
2023-08-13 |
xenopus_laevis |
| Johan-Till Pougnet, Benjamin Compans, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabo. P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons. Scientific reports. vol 6. 2018-05-22. PMID:27624155. |
atp- and lnmda-induced depression in the ca1 region of the hippocampus are additive, suggesting distinct molecular pathways. |
2018-05-22 |
2023-08-13 |
xenopus_laevis |
| Johan-Till Pougnet, Benjamin Compans, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabo. P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons. Scientific reports. vol 6. 2018-05-22. PMID:27624155. |
finally, using phosphorylation site-specific antibodies, we show that p2x-induced depression in hippocampal slices produces a dephosphorylation of the glua1 subunit at s567, contrary to nmdar-mediated ltd. |
2018-05-22 |
2023-08-13 |
xenopus_laevis |
| Anna Pink, Scott A Przybelski, Janina Krell-Roesch, Gorazd B Stokin, Rosebud O Roberts, Michelle M Mielke, David S Knopman, Clifford R Jack, Ronald C Petersen, Yonas E Ged. Cortical Thickness and Depressive Symptoms in Cognitively Normal Individuals: The Mayo Clinic Study of Aging. Journal of Alzheimer's disease : JAD. vol 58. issue 4. 2018-05-22. PMID:28550256. |
furthermore, reduced hippocampal volume has been reported in late-life depression. |
2018-05-22 |
2023-08-13 |
human |
| Maryam Ardalan, Gregers Wegener, Ali H Rafati, Jens R Nyengaar. S-Ketamine Rapidly Reverses Synaptic and Vascular Deficits of Hippocampus in Genetic Animal Model of Depression. The international journal of neuropsychopharmacology. vol 20. issue 3. 2018-05-21. PMID:27815416. |
s-ketamine rapidly reverses synaptic and vascular deficits of hippocampus in genetic animal model of depression. |
2018-05-21 |
2023-08-13 |
rat |
| Maryam Ardalan, Gregers Wegener, Ali H Rafati, Jens R Nyengaar. S-Ketamine Rapidly Reverses Synaptic and Vascular Deficits of Hippocampus in Genetic Animal Model of Depression. The international journal of neuropsychopharmacology. vol 20. issue 3. 2018-05-21. PMID:27815416. |
the neurovascular plasticity of hippocampus is an important theory underlying major depression. |
2018-05-21 |
2023-08-13 |
rat |
| Shu Liu, Tingfu Du, Zeyue Liu, Yan Shen, Jianbo Xiu, Qi X. Inverse changes in L1 retrotransposons between blood and brain in major depressive disorder. Scientific reports. vol 6. 2018-05-18. PMID:27874048. |
furthermore, l1 copy number in peripheral blood and five brain regions (prefrontal cortex, hippocampus, amygdala, nucleus accumbens and paraventricular hypothalamic nucleus) was measured in the chronic unpredictable mild stress (cums) model of depression in mice. |
2018-05-18 |
2023-08-13 |
mouse |
| Gonzalo García-Rojo, Cristóbal Fresno, Natalia Vilches, Gabriela Díaz-Véliz, Sergio Mora, Felipe Aguayo, Aníbal Pacheco, Nicolás Parra-Fiedler, Claudio S Parra, Paulina S Rojas, Macarena Tejos, Esteban Aliaga, Jenny L Fiedle. The ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat Hippocampus. The international journal of neuropsychopharmacology. vol 20. issue 4. 2018-05-18. PMID:27927737. |
dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. |
2018-05-18 |
2023-08-13 |
rat |
| Miroslav Adzic, Milos Mitic, Marija Radojci. Mitochondrial estrogen receptors as a vulnerability factor of chronic stress and mediator of fluoxetine treatment in female and male rat hippocampus. Brain research. vol 1671. 2018-05-17. PMID:28716632. |
in this study, we examined the effects of antidepressant (ad) fluoxetine (flu) treatment on the mitochondrial er alpha (erα), er beta (total and phospho-perβ) and their association with cytochrome c (cyt c) oxidase activity and apoptotic bcl2/bax-molecules in the hippocampal mitochondria of chronically isolated (cpsi) female and male rats depicting depression. |
2018-05-17 |
2023-08-13 |
rat |
| Xiang Cheng, Dong-Mei Wang, Xin Chen, Wo Wang, Chuan Liu, Tao He, Ling He, Qi-Zhong Qi. [Health Qigong Wuqinxi improves hydrogen proton magnetic resonance spectra in prefrontal cortex and hippocampus in college students with mild depression]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 36. issue 11. 2018-05-10. PMID:27881335. |
[health qigong wuqinxi improves hydrogen proton magnetic resonance spectra in prefrontal cortex and hippocampus in college students with mild depression]. |
2018-05-10 |
2023-08-13 |
Not clear |
| Canan Yurttas, Christoph Schmitz, Mehmet Turgut, Tatyana Strekalova, Harry W M Steinbusc. The olfactory bulbectomized rat model is not an appropriate model for studying depression based on morphological/stereological studies of the hippocampus. Brain research bulletin. vol 134. 2018-05-07. PMID:28734903. |
the olfactory bulbectomized rat model is not an appropriate model for studying depression based on morphological/stereological studies of the hippocampus. |
2018-05-07 |
2023-08-13 |
rat |
| Yu Wang, Huili Jiang, Hong Meng, Jun Lu, Jing Li, Xuhui Zhang, Xinjing Yang, Bingcong Zhao, Yang Sun, Tuya Ba. Genome-wide transcriptome analysis of hippocampus in rats indicated that TLR/NLR signaling pathway was involved in the pathogenisis of depressive disorder induced by chronic restraint stress. Brain research bulletin. vol 134. 2018-05-07. PMID:28780410. |
to elucidate the potential effects of acupuncture for depression on the hippocampal genome-wide transcriptome at the molecular level, we evaluated the transcriptomic profile of depression rats under treatment of acupuncture, and fluoxetine. |
2018-05-07 |
2023-08-13 |
rat |
| Hiroaki Norimoto, Kenichi Makino, Mengxuan Gao, Yu Shikano, Kazuki Okamoto, Tomoe Ishikawa, Takuya Sasaki, Hiroyuki Hioki, Shigeyoshi Fujisawa, Yuji Ikegay. Hippocampal ripples down-regulate synapses. Science (New York, N.Y.). vol 359. issue 6383. 2018-05-03. PMID:29439023. |
we report that mouse hippocampal sharp-wave ripple oscillations serve as intrinsic events that trigger long-lasting synaptic depression. |
2018-05-03 |
2023-08-13 |
mouse |
| Oliver Kaut, Amit Sharma, Ina Schmitt, René Hurlemann, Ullrich Wüllne. DNA methylation of DLG4 and GJA-1 of human hippocampus and prefrontal cortex in major depression is unchanged in comparison to healthy individuals. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 43. 2018-05-01. PMID:28645745. |
dna methylation of dlg4 and gja-1 of human hippocampus and prefrontal cortex in major depression is unchanged in comparison to healthy individuals. |
2018-05-01 |
2023-08-13 |
human |