| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Merete Osler, Lauge Sørensen, Maarten Rozing, Oriol Puig Calvo, Mads Nielsen, Egill Rostru. Subclinical depressive symptoms during late midlife and structural brain alterations: A longitudinal study of Danish men born in 1953. Human brain mapping. vol 39. issue 4. 2018-12-17. PMID:29322596. |
amygdala and hippocampal textures might be the early markers for brain alterations associated with depression in midlife. |
2018-12-17 |
2023-08-13 |
Not clear |
| M G Gottschalk, P Mortas, M Haman, S Ozcan, B Biemans, S Bah. Fluoxetine, not donepezil, reverses anhedonia, cognitive dysfunctions and hippocampal proteome changes during repeated social defeat exposure. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 28. issue 1. 2018-12-11. PMID:29174946. |
we evaluated the behavioural and molecular effects of a selective serotonin re-uptake inhibitor (ssri, fluoxetine) and an acetylcholinesterase inhibitor (achei, donepezil) on emotional-cognitive endophenotypes of depression and the hippocampal proteome. |
2018-12-11 |
2023-08-13 |
Not clear |
| Fabian Dammann, Timo Kirschstein, Xiati Guli, Steffen Müller, Katrin Porath, Marco Rohde, Tursonjan Tokay, Rüdiger Köhlin. Bidirectional shift of group III metabotropic glutamate receptor-mediated synaptic depression in the epileptic hippocampus. Epilepsy research. vol 139. 2018-12-11. PMID:29224956. |
bidirectional shift of group iii metabotropic glutamate receptor-mediated synaptic depression in the epileptic hippocampus. |
2018-12-11 |
2023-08-13 |
rat |
| Yuqing Zhang, Shuai Yuan, Juncai Pu, Lining Yang, Xinyu Zhou, Lanxiang Liu, Xiaofeng Jiang, Hanping Zhang, Teng Teng, Lu Tian, Peng Xi. Integrated Metabolomics and Proteomics Analysis of Hippocampus in a Rat Model of Depression. Neuroscience. vol 371. 2018-12-11. PMID:29237567. |
integrated metabolomics and proteomics analysis of hippocampus in a rat model of depression. |
2018-12-11 |
2023-08-13 |
rat |
| Yuqing Zhang, Shuai Yuan, Juncai Pu, Lining Yang, Xinyu Zhou, Lanxiang Liu, Xiaofeng Jiang, Hanping Zhang, Teng Teng, Lu Tian, Peng Xi. Integrated Metabolomics and Proteomics Analysis of Hippocampus in a Rat Model of Depression. Neuroscience. vol 371. 2018-12-11. PMID:29237567. |
in this study, we applied an integrated analysis of gas chromatography/mass spectrometry (gc-ms)-based metabolomics and isobaric tags for relative and absolute quantitation (itraq)-based proteomics to investigate changes in the hippocampus in the chronic unpredictable mild stress (cums) rat model of depression. |
2018-12-11 |
2023-08-13 |
rat |
| Martin H Teicher, Carl M Anderson, Kyoko Ohashi, Alaptagin Khan, Cynthia E McGreenery, Elizabeth A Bolger, Michael L Rohan, Gordana D Vitalian. Differential effects of childhood neglect and abuse during sensitive exposure periods on male and female hippocampus. NeuroImage. vol 169. 2018-12-11. PMID:29288867. |
the hippocampus is a highly stress susceptible structure and hippocampal abnormalities have been reported in a host of psychiatric disorders including major depression and post-traumatic stress disorder (ptsd). |
2018-12-11 |
2023-08-13 |
human |
| Ece Durmusoglu, Onur Ugurlu, Sebnem Akan, Fatma Simsek, Gozde Kizilates, Omer Kitis, Burcu Aksoy Ozkul, Cagdas Eker, Kerry L Coburn, Ali Saffet Gonu. Hippocampal shape alterations in healthy young women with familial risk for unipolar depression. Comprehensive psychiatry. vol 82. 2018-12-11. PMID:29367060. |
hippocampal shape alterations in healthy young women with familial risk for unipolar depression. |
2018-12-11 |
2023-08-13 |
human |
| Ece Durmusoglu, Onur Ugurlu, Sebnem Akan, Fatma Simsek, Gozde Kizilates, Omer Kitis, Burcu Aksoy Ozkul, Cagdas Eker, Kerry L Coburn, Ali Saffet Gonu. Hippocampal shape alterations in healthy young women with familial risk for unipolar depression. Comprehensive psychiatry. vol 82. 2018-12-11. PMID:29367060. |
the aim of the present study was to understand the anatomical status of the hippocampus prior to the clinical symptoms in subjects with high familial risk for depression. |
2018-12-11 |
2023-08-13 |
human |
| Oliver von Bohlen Und Halbach, Viola von Bohlen Und Halbac. BDNF effects on dendritic spine morphology and hippocampal function. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29450725. |
specific changes in dendritic spines as well as in adult hippocampal neurogenesis can be seen in the context of several forms of learning and memory, and it is known that depression is accompanied by declines in the rate of adult neurogenesis and in spine densities. |
2018-12-11 |
2023-08-13 |
Not clear |
| Elke Edelmann, Volkmar Lessman. Dopaminergic innervation and modulation of hippocampal networks. Cell and tissue research. vol 373. issue 3. 2018-12-11. PMID:29470647. |
in this chapter of the special issue "hippocampal structure and function," we will discuss the current understanding of dopaminergic modulation of basal synaptic transmission and long-lasting, activity-dependent potentiation or depression. |
2018-12-11 |
2023-08-13 |
Not clear |
| Min Lin, Gonglin Hou, Ying Zhao, Ti-Fei Yua. Recovery of Chronic Stress-Triggered Changes of Hippocampal Glutamatergic Transmission. Neural plasticity. vol 2018. 2018-11-26. PMID:29666637. |
the hippocampus has been one major focus in studying the stress responsivity and neural mechanisms underlying depression. |
2018-11-26 |
2023-08-13 |
Not clear |
| Rose M De Guzman, Angela I Saulsbery, Joanna L Workma. High nursing demand reduces depression-like behavior despite increasing glucocorticoid concentrations and reducing hippocampal neurogenesis in late postpartum rats. Behavioural brain research. vol 353. 2018-11-26. PMID:30031882. |
because the hippocampus changes structurally in depression and with maternal experience, we investigated cell proliferation using ki-67 and hippocampal neurogenesis and immature neuron development using doublecortin (dcx) immunohistochemistry. |
2018-11-26 |
2023-08-13 |
rat |
| Juhee Lim, Yeojin Bang, Hyun Jin Cho. Abnormal hippocampal neurogenesis in Parkinson's disease: relevance to a new therapeutic target for depression with Parkinson's disease. Archives of pharmacal research. vol 41. issue 10. 2018-11-21. PMID:30136247. |
abnormal hippocampal neurogenesis in parkinson's disease: relevance to a new therapeutic target for depression with parkinson's disease. |
2018-11-21 |
2023-08-13 |
human |
| Juhee Lim, Yeojin Bang, Hyun Jin Cho. Abnormal hippocampal neurogenesis in Parkinson's disease: relevance to a new therapeutic target for depression with Parkinson's disease. Archives of pharmacal research. vol 41. issue 10. 2018-11-21. PMID:30136247. |
altered adult hippocampal neurogenesis is considered crucial for the development and treatment of depression. |
2018-11-21 |
2023-08-13 |
human |
| Juhee Lim, Yeojin Bang, Hyun Jin Cho. Abnormal hippocampal neurogenesis in Parkinson's disease: relevance to a new therapeutic target for depression with Parkinson's disease. Archives of pharmacal research. vol 41. issue 10. 2018-11-21. PMID:30136247. |
we present a novel framework for targeting adult hippocampal neurogenesis, which could provide a promising treatment for pd-associated depression. |
2018-11-21 |
2023-08-13 |
human |
| Slavianka Moyanova, Antonio De Fusco, Ines Santolini, Roberta Celli, Domenico Bucci, Federica Mastroiacovo, Giuseppe Battaglia, Ferdinando Nicoletti, Jane Tchekalarov. Abnormal Hippocampal Melatoninergic System: A Potential Link between Absence Epilepsy and Depression-Like Behavior in WAG/Rij Rats? International journal of molecular sciences. vol 19. issue 7. 2018-11-15. PMID:29986414. |
these findings suggest that a defect of hippocampal melatoninergic system may be one of the mechanisms underlying the depression-like phenotype in wag/rij rats and that activation of melatonin receptors might represent a valuable strategy in the treatment of depression associated with absence epilepsy. |
2018-11-15 |
2023-08-13 |
rat |
| Yong He, Wei Li, Yu Tian, Xi Chen, Ke Cheng, Ke Xu, Chenmeng Li, Haiyang Wang, Chaohua Qu, Chunlian Wang, Pengfei Li, Huanxin Chen, Peng Xi. iTRAQ-based proteomics suggests LRP6, NPY and NPY2R perturbation in the hippocampus involved in CSDS may induce resilience and susceptibility. Life sciences. vol 211. 2018-11-15. PMID:30201296. |
although decades of research have revealed numerous molecular abnormalities in the hippocampus associated with depression, the different mechanisms involved in the susceptibility and resilience of mice to chronic social defeat stress (csds)-induced depression remain poorly understand. |
2018-11-15 |
2023-08-13 |
mouse |
| Ahmad Raza Khan, Brian Hansen, Ove Wiborg, Christopher D Kroenke, Sune Nørhøj Jesperse. Diffusion MRI and MR spectroscopy reveal microstructural and metabolic brain alterations in chronic mild stress exposed rats: A CMS recovery study. NeuroImage. vol 167. 2018-11-08. PMID:29196269. |
cms exposure induces significant metabolic and microstructural alterations in the hippocampus (hp), prefrontal cortex (pfc), caudate-putamen (cp) and amygdala (am), however, recovery from these maladaptive changes are limited and this may provide negative effects on the therapeutic treatment and management of depression. |
2018-11-08 |
2023-08-13 |
rat |
| Ahmad Raza Khan, Brian Hansen, Ove Wiborg, Christopher D Kroenke, Sune Nørhøj Jesperse. Diffusion MRI and MR spectroscopy reveal microstructural and metabolic brain alterations in chronic mild stress exposed rats: A CMS recovery study. NeuroImage. vol 167. 2018-11-08. PMID:29196269. |
the present study utilized anhedonic rats from the unpredictable cms model of depression to study metabolic recovery in the ventral hippocampus (vhp) and microstructural recovery in the hp, am, cp, and pfc. |
2018-11-08 |
2023-08-13 |
rat |
| Shenglan Gong, Jin Zhang, Zhouke Guo, Wenjun F. Senkyunolide A protects neural cells against corticosterone-induced apoptosis by modulating protein phosphatase 2A and α-synuclein signaling. Drug design, development and therapy. vol 12. 2018-10-31. PMID:29983543. |
depression is characterized by a pathological injury to the hippocampal neurons. |
2018-10-31 |
2023-08-13 |
Not clear |