| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jian Liu, Han-Xiao Zhu, Wan-Li Fu, Xin-Wei Xu, Jun-Zhe Yang, Dan Dai, Yun L. Downregulated hippocampal expression of brain derived neurotrophic factor and tyrosine kinase B in a rat model of comorbid epilepsy and depression. Neurological research. vol 41. issue 5. 2019-04-18. PMID:30741614. |
to investigate the expression of brain-derived neurotrophic factor(bdnf) and tyrosine kinase b (trkb) protein in the hippocampus of model rats of comorbid epilepsy and depression. |
2019-04-18 |
2023-08-13 |
rat |
| Cai Zhang, Yong-Ping Zhang, Yu-Yu Li, Bai-Ping Liu, Hao-Yin Wang, Kang-Wei Li, Shannon Zhao, Cai Son. Minocycline ameliorates depressive behaviors and neuro-immune dysfunction induced by chronic unpredictable mild stress in the rat. Behavioural brain research. vol 356. 2019-04-16. PMID:30003978. |
hence, the chronic unpredictable mild stress (cums)-induced depression model was chosen to study depression- and anxiety-like behaviors, the concentration of corticosterone and relevant hippocampal cytokines, mrna and protein expressions of microglial and astrocyte markers. |
2019-04-16 |
2023-08-13 |
rat |
| Yong-Ku Kim, Byung-Joo Ham, Kyu-Man Ha. Interactive effects of genetic polymorphisms and childhood adversity on brain morphologic changes in depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 91. 2019-04-15. PMID:29535036. |
the s allele of 5-httlpr combined with exposure to childhood adversity or a poorer parenting environment was associated with a smaller hippocampal volume and subsequent onset of depression. |
2019-04-15 |
2023-08-13 |
Not clear |
| Qin Dai, Xuntao Yin, Hong Li, Zhengzhi Fen. Orbito-frontal cortex mechanism of inhibition of return in current and remitted depression. Human brain mapping. vol 39. issue 7. 2019-04-15. PMID:29575563. |
moreover, the hippocampus, a less-known cortex in ior, showed a contrary model, that is, lower activation in depression remission and higher task- and resting-state activation in depressive episodes. |
2019-04-15 |
2023-08-13 |
Not clear |
| Qin Dai, Xuntao Yin, Hong Li, Zhengzhi Fen. Orbito-frontal cortex mechanism of inhibition of return in current and remitted depression. Human brain mapping. vol 39. issue 7. 2019-04-15. PMID:29575563. |
the results suggest the ofc mechanism of the ior effect in remitted depression and the hippocampus mechanism of the ior effect in depressive episodes, which offer potential biomarkers for the clinical treatment of depression. |
2019-04-15 |
2023-08-13 |
Not clear |
| Hanjie Yu, Dan Lv, Mengxin Shen, Yanhua Zhang, Dongsheng Zhou, Zhongming Chen, Chuang Wan. BDNF mediates the protective effects of scopolamine in reserpine-induced depression-like behaviors via up-regulation of 5-HTT and TPH1. Psychiatry research. vol 271. 2019-04-15. PMID:30529315. |
our study provides evidence that scopolamine rapidly attenuates reserpine-induced depression in mice partially by regulating 5-htt, bdnf and tph1 in the hippocampus and pfc of mice. |
2019-04-15 |
2023-08-13 |
mouse |
| Sha Dong, Hui-Li Jiang, Yu Wang, Jun Lu, Lei Chang, Peng Zhang, Sui-Cheng Xin, Ya T. [Effect of Acupuncture on Expression of Glial Fibrillary Acidic Protein in Hippocampus and Prefrontal Cortex and Serum Interleukin-10 in Chronic Restraint Stress Depression Rats]. Zhen ci yan jiu = Acupuncture research. vol 43. issue 4. 2019-04-03. PMID:29888572. |
[effect of acupuncture on expression of glial fibrillary acidic protein in hippocampus and prefrontal cortex and serum interleukin-10 in chronic restraint stress depression rats]. |
2019-04-03 |
2023-08-13 |
rat |
| Sha Dong, Hui-Li Jiang, Yu Wang, Jun Lu, Lei Chang, Peng Zhang, Sui-Cheng Xin, Ya T. [Effect of Acupuncture on Expression of Glial Fibrillary Acidic Protein in Hippocampus and Prefrontal Cortex and Serum Interleukin-10 in Chronic Restraint Stress Depression Rats]. Zhen ci yan jiu = Acupuncture research. vol 43. issue 4. 2019-04-03. PMID:29888572. |
to observe the effect of acupuncture on the expression of glial fibrillary acidic protein (gfap) in hippocampus and prefrontal cortex and the level of serum interleukin 10 (il-10) in rats with depression, so as to explore its mechanism underlying improvement of depression. |
2019-04-03 |
2023-08-13 |
rat |
| Ruyi Zhang, Zhongxuan Ma, Kaili Liu, Yawei Li, Dongni Liu, Lixing Xu, Xueyang Deng, Rong Qu, Zhanqiang Ma, Shiping M. Baicalin exerts antidepressant effects through Akt/FOXG1 pathway promoting neuronal differentiation and survival. Life sciences. vol 221. 2019-04-03. PMID:30794828. |
impaired neurogenesis in hippocampus may contribute to a variety of neurological diseases, such as alzheimer's disease and depression. |
2019-04-03 |
2023-08-13 |
Not clear |
| Rebeca Vidal, Emilio Garro-Martínez, Álvaro Díaz, Elena Castro, Eva Florensa-Zanuy, Makoto M Taketo, Ángel Pazos, Fuencisla Pilar-Cuélla. Targeting β-Catenin in GLAST-Expressing Cells: Impact on Anxiety and Depression-Related Behavior and Hippocampal Proliferation. Molecular neurobiology. vol 56. issue 1. 2019-04-01. PMID:29737454. |
to further understand the role of β-catenin in depression and anxiety, we generated two conditional transgenic mice in which β-catenin was either inactivated or stabilized in cells expressing creert under the control of the astrocyte-specific glutamate transporter (glast) promoter inducible by tamoxifen, which presents high expression levels on the subgranular zone of the hippocampus. |
2019-04-01 |
2023-08-13 |
mouse |
| Patrick Dutar, Virginie Tolle, Myriam Kervern, Carole Carcenac, Valeria Carola, Cornelius Gross, Marc Savasta, Michèle Darmon, Justine Masso. GLS1 Mutant Mice Display Moderate Alterations of Hippocampal Glutamatergic Neurotransmission Associated with Specific Adaptive Behavioral Changes. Neuroscience. vol 396. 2019-04-01. PMID:30472430. |
as cognitive deficits such as hippocampus-memory process were observed in mdd, we investigated in a mild hypoglutamatergic model behaviors related to depression and memory, synaptic transmission parameters and glutamatergic state specifically in the hippocampus. |
2019-04-01 |
2023-08-13 |
mouse |
| Lina Jia, Zuoli Sun, Dandan Shi, Min Wang, Jun Jia, Yi He, Fenqin Xue, Yanping Ren, Jian Yang, Xin M. Effects of different patterns of electric stimulation of the ventromedial prefrontal cortex on hippocampal-prefrontal coherence in a rat model of depression. Behavioural brain research. vol 356. 2019-03-22. PMID:30179639. |
neuronal communication between the hippocampus and ventral medial prefrontal cortex (vmpfc) may play an important role in emotional processes relevant to depression. |
2019-03-22 |
2023-08-13 |
rat |
| Connor Thelen, Emily Flaherty, Joseph Saurine, Jonathon Sens, Sara Mohamed, Pothitos M Pitychouti. Sex Differences in the Temporal Neuromolecular and Synaptogenic Effects of the Rapid-acting Antidepressant Drug Ketamine in the Mouse Brain. Neuroscience. vol 398. 2019-03-18. PMID:30537521. |
preclinical evidence suggests that ketamine's rapid and sustained antidepressant actions are due to the induction of synaptogenesis in the medial prefrontal cortex (mpfc) and the hippocampus (hipp), two brain regions implicated in the pathophysiology of major depression. |
2019-03-18 |
2023-08-13 |
mouse |
| Mateusz Kucharczyk, Anna Kurek, Bartosz Pomierny, Jan Detka, Mariusz Papp, Katarzyna Tota, Bogusława Budziszewsk. The reduced level of growth factors in an animal model of depression is accompanied by regulated necrosis in the frontal cortex but not in the hippocampus. Psychoneuroendocrinology. vol 94. 2019-03-15. PMID:29775875. |
the reduced level of growth factors in an animal model of depression is accompanied by regulated necrosis in the frontal cortex but not in the hippocampus. |
2019-03-15 |
2023-08-13 |
rat |
| Xuke Han, Huangan Wu, Ping Yin, Zeqin Chen, Xiaohua Cao, Yanhong Duan, Jian Xu, Lixing Lao, Shifen X. Electroacupuncture restores hippocampal synaptic plasticity via modulation of 5-HT receptors in a rat model of depression. Brain research bulletin. vol 139. 2019-03-12. PMID:29524471. |
electroacupuncture restores hippocampal synaptic plasticity via modulation of 5-ht receptors in a rat model of depression. |
2019-03-12 |
2023-08-13 |
rat |
| Lin Zhao, Huicong Ren, Shina Gu, Xiaodan Li, Cuihong Jiang, Juan Li, Mengmeng Zhang, Junlin Mu, Wenqiang Li, Wensheng Wang, Zhaohui Zhang, Jinggui Son. rTMS ameliorated depressive-like behaviors by restoring HPA axis balance and prohibiting hippocampal neuron apoptosis in a rat model of depression. Psychiatry research. vol 269. 2019-03-11. PMID:30145293. |
rtms ameliorated depressive-like behaviors by restoring hpa axis balance and prohibiting hippocampal neuron apoptosis in a rat model of depression. |
2019-03-11 |
2023-08-13 |
rat |
| Lin Zhao, Huicong Ren, Shina Gu, Xiaodan Li, Cuihong Jiang, Juan Li, Mengmeng Zhang, Junlin Mu, Wenqiang Li, Wensheng Wang, Zhaohui Zhang, Jinggui Son. rTMS ameliorated depressive-like behaviors by restoring HPA axis balance and prohibiting hippocampal neuron apoptosis in a rat model of depression. Psychiatry research. vol 269. 2019-03-11. PMID:30145293. |
thus, rtms abrogates the loss of hippocampal neurons and restores the balance of the hpa axis in the treatment of depression. |
2019-03-11 |
2023-08-13 |
rat |
| Maria Pina Serra, Laura Poddighe, Marianna Boi, Francesco Sanna, Maria Antonietta Piludu, Fabrizio Sanna, Maria G Corda, Osvaldo Giorgi, Marina Quart. Effect of Acute Stress on the Expression of BDNF, trkB, and PSA-NCAM in the Hippocampus of the Roman Rats: A Genetic Model of Vulnerability/Resistance to Stress-Induced Depression. International journal of molecular sciences. vol 19. issue 12. 2019-03-08. PMID:30477252. |
effect of acute stress on the expression of bdnf, trkb, and psa-ncam in the hippocampus of the roman rats: a genetic model of vulnerability/resistance to stress-induced depression. |
2019-03-08 |
2023-08-13 |
rat |
| Joshua C Gray, Max M Owens, Courtland S Hyatt, Joshua D Mille. No evidence for morphometric associations of the amygdala and hippocampus with the five-factor model personality traits in relatively healthy young adults. PloS one. vol 13. issue 9. 2019-03-05. PMID:30235257. |
despite some previous positive findings of whole amygdala and hippocampus with personality traits and related psychopathology (e.g., depression), the current results indicated no relationships between the any of the brain regions and the ffm personality traits. |
2019-03-05 |
2023-08-13 |
human |
| Mehrdad Salmasi, Alex Loebel, Stefan Glasauer, Martin Stemmle. Short-term synaptic depression can increase the rate of information transfer at a release site. PLoS computational biology. vol 15. issue 1. 2019-02-28. PMID:30601804. |
in hippocampal autaptic synapses, the persistence of asynchronous release during depression cannot compensate for the reduction of synchronous release, so that the rate of information transmission declines with synaptic depression. |
2019-02-28 |
2023-08-13 |
Not clear |