| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M B Pavlova, D A Smagin, N N Kudryavtseva, N A Dyuzhnikov. [Changes in Expression of Genes Associated with Calcium Processes in the Hippocampus in Mice Exposed to Chronic Social Stress]. Molekuliarnaia biologiia. vol 57. issue 2. 2023-03-31. PMID:37000665. |
whole-transcriptome data were used to study the changes in expression of genes coding proteins involved in the calcium regulation processes in the hippocampus of male mice with symptoms of depression caused by chronic social defeat stress. |
2023-03-31 |
2023-08-14 |
mouse |
| Hong Zhang, Lian He, Songfei Li, Manhuayun Zhai, Siman Ma, Ge Jin, Minyan Li, Fan Zhou, Hua Tian, Tuohutanguli Nuerkaman, Qiruo Sun, Yu Zhang, Jincai Hou, Guoxiang Sun, Shiliang Yi. Cerebral iron deficiency may induce depression through downregulation of the hippocampal glucocorticoid-glucocorticoid receptor signaling pathway. Journal of affective disorders. 2023-03-31. PMID:37001697. |
cerebral iron deficiency may induce depression through downregulation of the hippocampal glucocorticoid-glucocorticoid receptor signaling pathway. |
2023-03-31 |
2023-08-14 |
human |
| Toshinori Yoshioka, Daisuke Yamada, Eri Segi-Nishida, Hiroshi Nagase, Akiyoshi Saito. KNT-127, a selective delta opioid receptor agonist, shows beneficial effects in the hippocampal dentate gyrus of a chronic vicarious social defeat stress mouse model. Neuropharmacology. 2023-03-31. PMID:37001727. |
the hypothalamic-pituitary-adrenal axis, adult hippocampal neurogenesis, and neuroinflammation are regarded as key pathophysiological factors in depression. |
2023-03-31 |
2023-08-14 |
mouse |
| Jinqiang Zhang, Qin Liu, Dapeng Su, Liangyuan Li, Chenghong Xiao, Hui He, Zili You, Tao Zho. Akebia saponin D acts via the PPAR-gamma pathway to reprogramme a pro-neurogenic microglia that can restore hippocampal neurogenesis in mice exposed to chronic mild stress. CNS neuroscience & therapeutics. 2023-03-29. PMID:36987659. |
akebia saponin d (asd) can cross the blood-brain barrier and exert anti-inflammatory and neuroprotective effects, so we wondered whether it might influence adult hippocampal neurogenesis to treat depression. |
2023-03-29 |
2023-08-14 |
mouse |
| Richard Baskerville, Thomas McGrath, Lindy Castel. The effects of physical activity on glutamate neurotransmission in neuropsychiatric disorders. Frontiers in sports and active living. vol 5. 2023-03-23. PMID:36949894. |
the hippocampus and pre-frontal cortex (pfc) containing predominantly glutamate neurotransmission, are the centres of changes seen in depression. |
2023-03-23 |
2023-08-14 |
Not clear |
| Richard Baskerville, Thomas McGrath, Lindy Castel. The effects of physical activity on glutamate neurotransmission in neuropsychiatric disorders. Frontiers in sports and active living. vol 5. 2023-03-23. PMID:36949894. |
a dynamic glutamate-based homeostatic model is suggested whereby stress, neuroinflammation and pa form counterbalancing influences on hippocampal cell functionality, which manifests as depression and other neuropsychiatric conditions when homeostasis is disrupted. |
2023-03-23 |
2023-08-14 |
Not clear |
| Chao Yu, Yiwen Ruan, Xiaobo Sun, Chen Chen, Ting Shen, Chunxin Liu, Wei Qiu, Zhengqi Lu, Sun On Chan, Liqing Wan. rTMS ameliorates depression/anxiety-like behaviors in experimental autoimmune encephalitis by inhibiting neurotoxic reactive astrocytes. Journal of affective disorders. 2023-03-23. PMID:36958487. |
the pathogenesis of depression in ms patients has been related to innate immune activation in certain regions of the brain such as hippocampus. |
2023-03-23 |
2023-08-14 |
mouse |
| Sofia Elisa Alzuri, Nicolás Matías Rosas, Natasa Hlavacova, Daniela Jezova, Beata Fuchsov. Role of miR-124-3p in regulatory mechanisms of Gpm6a expression in the hippocampus of chronically stressed rats. Journal of neurochemistry. 2023-03-21. PMID:36943192. |
decreased expression of gpm6a mrna is observed in the hippocampal tissue of suicide victims who suffered from depression and after chronic stress exposure in animals. |
2023-03-21 |
2023-08-14 |
rat |
| Ivan J Torres, Ruiyang Ge, Alexander McGirr, Fidel Vila-Rodriguez, Sharon Ahn, Jayasree Basivireddy, Nazlin Walji, Sophia Frangou, Raymond W Lam, Lakshmi N Yatha. Effects of intermittent theta-burst transcranial magnetic stimulation on cognition and hippocampal volumes in bipolar depression. Dialogues in clinical neuroscience. vol 25. issue 1. 2023-03-16. PMID:36924413. |
effects of intermittent theta-burst transcranial magnetic stimulation on cognition and hippocampal volumes in bipolar depression. |
2023-03-16 |
2023-08-14 |
Not clear |
| Ivan J Torres, Ruiyang Ge, Alexander McGirr, Fidel Vila-Rodriguez, Sharon Ahn, Jayasree Basivireddy, Nazlin Walji, Sophia Frangou, Raymond W Lam, Lakshmi N Yatha. Effects of intermittent theta-burst transcranial magnetic stimulation on cognition and hippocampal volumes in bipolar depression. Dialogues in clinical neuroscience. vol 25. issue 1. 2023-03-16. PMID:36924413. |
this study evaluated whether itbs leads to cognitive improvements and associated increased hippocampal volumes in bipolar depression. |
2023-03-16 |
2023-08-14 |
Not clear |
| Zita Dósa, Jose Luis Nieto-Gonzalez, Betina Elfving, Karin Sørig Hougaard, Mai Marie Holm, Gregers Wegener, Kimmo Jense. Reduction in hippocampal GABAergic transmission in a low birth weight rat model of depression. Acta neuropsychiatrica. 2023-03-10. PMID:36896595. |
reduction in hippocampal gabaergic transmission in a low birth weight rat model of depression. |
2023-03-10 |
2023-08-14 |
rat |
| Alzbeta Idunkova, Lubica Lacinova, Lucia Dubiel-Hoppanov. Stress, depression, and hippocampus: from biochemistry to electrophysiology. General physiology and biophysics. vol 42. issue 2. 2023-03-10. PMID:36896941. |
an important role in the pathology of depression is the hippocampus as a center for cognition and memory. |
2023-03-10 |
2023-08-14 |
Not clear |
| Bin Xi, Jieping Fu, Dengfeng Wan, Zhiping Xi. Ginsenoside Rg1 attenuation of neurogenesis disorder and neuronal apoptosis in the rat hippocampus after spinal cord injury may involve brain-derived neurotrophic factor/extracellular signal-regulated kinase signaling. Neuroreport. vol 34. issue 5. 2023-03-07. PMID:36881751. |
we previously demonstrated that spinal cord injury (sci) induced hippocampus injury and depression in rodents. |
2023-03-07 |
2023-08-14 |
rat |
| Bao Gong, Can-Hong Wang, Yu-Lan Wu, Yang-Yang Liu, Jian-He We. [Anxiolytic and antidepressant effects of agarwood inhalation and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 4. 2023-03-05. PMID:36872273. |
at the same time, the aeo, afp, and ali groups all increased the protein expression levels of glur1 and vglut1 in the hippocampus of the rat models of anxiety and depression(p<0.05). |
2023-03-05 |
2023-08-14 |
rat |
| Yi Chung, Jia-Ling Wu, Wen-Ching Huan. Effects of prebiotics on intestinal physiology, neuropsychological function, and exercise capacity of mice with sleep deprivation. Food research international (Ottawa, Ont.). vol 165. 2023-03-04. PMID:36869551. |
in hypothalamus and hippocampus, clock (bmal1 and clock) and tight junction (ocln and tjp2) genes were improved by prebiotics, and corticotropin-releasing hormone receptor genes, crf1 and crf2, were also significantly regulated for mitigation of depression and anxiety caused by sleep deprivation. |
2023-03-04 |
2023-08-14 |
mouse |
| Dimitar Bakalov, Petar Iliev, Zafer Sabit, Radka Tafradjiiska-Hadjiolova, Georgeta Bochev. Attenuation of Hypothyroidism-Induced Cognitive Impairment by Modulating Serotonin Mediation. Veterinary sciences. vol 10. issue 2. 2023-02-28. PMID:36851426. |
a staggering amount of research is suggesting that the common denominators in the pathophysiology of depression and the behavior changes in hypothyroidism are the hippocampal complex and the distorted serotonin metabolism. |
2023-02-28 |
2023-08-14 |
rat |
| Shi Yan, Chang Xu, Mengli Yang, Huiqiang Zhang, Ye Cheng, Zeping Xue, Zecong He, Tiantian Wang, Shangying Bai, Gang Wang, Jianping Wu, Zhiqian Tong, Xiang Ca. The expression of agmatinase manipulates the affective state of rats subjected to chronic restraint stress. Neuropharmacology. 2023-02-27. PMID:36849038. |
in this study, we observed that agmat expression increased in the ventral hippocampus rather than in the medial prefrontal cortex in the chronic restraint stress (crs) animal model of depression. |
2023-02-27 |
2023-08-14 |
rat |
| Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Ryo Yamamoto, Takafumi Furuyama, Yasuhito Ishigaki, Nobuo Kato, Hideto Yonekura, Takayuki Iked. Transthyretin Is Commonly Upregulated in the Hippocampus of Two Stress-Induced Depression Mouse Models. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835151. |
transthyretin is commonly upregulated in the hippocampus of two stress-induced depression mouse models. |
2023-02-25 |
2023-08-14 |
mouse |
| Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Ryo Yamamoto, Takafumi Furuyama, Yasuhito Ishigaki, Nobuo Kato, Hideto Yonekura, Takayuki Iked. Transthyretin Is Commonly Upregulated in the Hippocampus of Two Stress-Induced Depression Mouse Models. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835151. |
chronic stress can affect gene expression in the hippocampus, which alters neural and cerebrovascular functions, thereby contributing to the development of mental disorders such as depression. |
2023-02-25 |
2023-08-14 |
mouse |
| Hidehito Saito-Takatsuji, Yasuo Yoshitomi, Ryo Yamamoto, Takafumi Furuyama, Yasuhito Ishigaki, Nobuo Kato, Hideto Yonekura, Takayuki Iked. Transthyretin Is Commonly Upregulated in the Hippocampus of Two Stress-Induced Depression Mouse Models. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835151. |
therefore, this study examines hippocampal gene expression in two mouse models of depression induced by forced swim stress (fss) and repeated social defeat stress (r-sds). |
2023-02-25 |
2023-08-14 |
mouse |