| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Xu, Bowen Zheng, Yanmei Ma, Xiaopeng Zhang, Jianhua Cheng, Jing Yang, Peng Li, Jianzhong Zhang, Li Jing, Fang X. PI3K-AKT-mTOR signaling pathway regulates autophagy of hippocampal neurons in diabetic rats with chronic unpredictable mild stress. Behavioural brain research. 2023-06-30. PMID:37390967. |
it is suggests that memory and cognitive impairment in rats with co-morbidities of diabetes and depression might be related with hippocampal neuronal damage and autophagy increase, which was involved in the pi3k-akt-mtor signaling pathway. |
2023-06-30 |
2023-08-14 |
rat |
| Omar Gammoh, Aseel Ibrahim, Esam Qnais, Abdelrahim Alqudah, Sara Altaber, Alaa A A Aljabali, Murtaza M Tambuwal. Vitamins C and D Exhibit Similar Antidepressant Effects to Escitalopram Mediated by NOx and FKBPL in a Stress-Induced Mice Model. Nutrients. vol 15. issue 12. 2023-06-28. PMID:37375593. |
future investigations should focus on examining these markers in specific brain regions, such as the hippocampus and prefrontal cortex, to gain a more comprehensive understanding of their potential implications for depression. |
2023-06-28 |
2023-08-14 |
mouse |
| Paola Brivio, Matteo Audano, Maria Teresa Gallo, Eleonora Miceli, Piotr Gruca, Magdalena Lason, Ewa Litwa, Fabio Fumagalli, Mariusz Papp, Nico Mitro, Francesca Calabres. Venlafaxine's effect on resilience to stress is associated with a shift in the balance between glucose and fatty acid utilization. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-06-28. PMID:37380799. |
the analyses were conducted in the ventral hippocampus (vhip) for its key role in the modulation of anhedonia, a core symptom of patients affected by depression. |
2023-06-28 |
2023-08-14 |
Not clear |
| Xin-Yuan Wu, Xiang Jin, Xiao-Ming Sheng, Yan Fan, Wei Gua. miR-204-5p plays a critical role in the pathogenesis of depression and anti-depression action of Venlafaxine in the hippocampus of mice. Current medicinal chemistry. 2023-06-26. PMID:37357509. |
mir-204-5p plays a critical role in the pathogenesis of depression and anti-depression action of venlafaxine in the hippocampus of mice. |
2023-06-26 |
2023-08-14 |
mouse |
| Qun Zhang, Xiwu Wang, Yuan Lin, Zhaoting Lv, Shuangda Miao, Yi Lu, Yiren Fan, Xiuchun Li, Yuanyuan Fang, Xuyi Pan, Zirun Chen, Hui Wang, Jia Li, Ying Wang, Jianliang Su. Virgin coconut oil attenuates lipopolysaccharide-induced depression-like behaviors: Integrating network pharmacology analysis and molecular mechanism evaluation. Neuroscience letters. 2023-06-16. PMID:37327854. |
we assessed the effects of vco on depression and the related mechanisms by performing network pharmacology analysis and evaluating depressive-like behaviors in rat model and found that vco-treatment alleviated the depressive-like behaviors, inhibited microglial and astrocytic activation and reduced neuronal loss in the hippocampus, possibly by decreasing neuronal apoptosis. |
2023-06-16 |
2023-08-14 |
rat |
| Natsuki Yoshimoto, Yoki Nakamura, Kazue Hisaoka-Nakashima, Norimitsu Moriok. Mitochondrial dysfunction and type I interferon signaling induce anxiodepressive-like behaviors in mice with neuropathic pain. Experimental neurology. 2023-06-16. PMID:37327964. |
improving mitochondrial dysfunction and inhibiting type i ifn signaling in the hippocampus might be a novel approach to reducing comorbidities associated with neuropathic pain, such as depression and anxiety. |
2023-06-16 |
2023-08-14 |
mouse |
| Jing Liu, Fantao Meng, Wentao Wang, Min Wu, Yu Zhang, Minghu Cui, Changyun Qiu, Fengai Hu, Di Zhao, Dan Wang, Cuilan Liu, Dunjiang Liu, Zhicheng Xu, Yameng Wang, Wei Li, Chen L. Medial prefrontal cortical PPM1F alters depression-related behaviors by modifying p300 activity via the AMPK signaling pathway. CNS neuroscience & therapeutics. 2023-06-13. PMID:37309288. |
protein phosphatase mg2+/mn2+-dependent 1f (ppm1f) is a serine/threonine phosphatase, and its dysfunction in depression in the hippocampal dentate gyrus has been previously identified. |
2023-06-13 |
2023-08-14 |
Not clear |
| Jakob Emil Schreiner, Ute Kessler, Ketil Joachim Oedegaard, Kent-Andre Mardal, Leif Olteda. Exploring New Electroencephalogram Parameters in Electroconvulsive Therapy. The journal of ECT. 2023-06-13. PMID:37310067. |
this pilot study aims to evaluate a novel metric based on the power spectrum of the eeg recordings from ect-induced seizures-its association to volume changes in the hippocampus after ect and improvement in depression rating scores. |
2023-06-13 |
2023-08-14 |
Not clear |
| Xuemei Li, Teng Teng, Wei Yan, Li Fan, Xueer Liu, Gerard Clarke, Dan Zhu, Yuanliang Jiang, Yajie Xiang, Ying Yu, Yuqing Zhang, Bangmin Yin, Lin Lu, Xinyu Zhou, Peng Xi. AKT and MAPK signaling pathways in hippocampus reveals the pathogenesis of depression in four stress-induced models. Translational psychiatry. vol 13. issue 1. 2023-06-12. PMID:37308476. |
akt and mapk signaling pathways in hippocampus reveals the pathogenesis of depression in four stress-induced models. |
2023-06-12 |
2023-08-14 |
rat |
| Manuela Dicarlo, Patrizia Pignataro, Roberta Zerlotin, Clelia Suriano, Chiara Zecca, Maria Teresa Dell'Abate, Giuseppina Storlino, Angela Oranger, Lorenzo Sanesi, Giorgio Mori, Maria Grano, Graziana Colaianni, Silvia Colucc. Short-Term Irisin Treatment Enhanced Neurotrophin Expression Differently in the Hippocampus and the Prefrontal Cortex of Young Mice. International journal of molecular sciences. vol 24. issue 11. 2023-06-11. PMID:37298063. |
to understand which molecular mechanisms might be involved in such effect, we here studied, in a group of mice previously submitted to a behavioral test of depression, the gene expression of neurotrophins and cytokines in the hippocampus and prefrontal cortex (pfc), two brain areas frequently investigated in the depression pathogenesis. |
2023-06-11 |
2023-08-14 |
mouse |
| Qiaoqi Zheng, Shusheng Wang, Xinyun Tian, Wen Liu, Pengfei Ga. Fecal microbiota transplantation confirmed that 919 Syrup reduced the ratio of erucamide to 5-AVAB in hippocampus to alleviate postpartum depression by regulating gut microbes. Frontiers in immunology. vol 14. 2023-06-09. PMID:37292211. |
fecal microbiota transplantation confirmed that 919 syrup reduced the ratio of erucamide to 5-avab in hippocampus to alleviate postpartum depression by regulating gut microbes. |
2023-06-09 |
2023-08-14 |
Not clear |
| Mate Abraham, Kirsten Schmerder, Malin Hedtstück, Kimberly Bösing, Annakarina Mundorf, Nadja Freun. Maternal separation and its developmental consequences on anxiety and parvalbumin interneurons in the amygdala. Journal of neural transmission (Vienna, Austria : 1996). 2023-06-09. PMID:37294327. |
altered gabaergic activity in the hippocampus and the amygdala have been identified in humans diagnosed with depression or anxiety disorders, as well as in respective animal models. |
2023-06-09 |
2023-08-14 |
rat |
| Zhaosong Chu, Lijin Yuan, Mengxin He, Yuqi Cheng, Yi Lu, Xiufeng Xu, Zonglin She. Atrophy of bilateral nucleus accumbens in melancholic depression. Neuroreport. vol 34. issue 10. 2023-06-04. PMID:37270840. |
however, few studies have investigated the structural alterations of the nac, hippocampus, and amygdala in depression with anhedonia as the main clinical manifestation. |
2023-06-04 |
2023-08-14 |
human |
| Zhaosong Chu, Lijin Yuan, Mengxin He, Yuqi Cheng, Yi Lu, Xiufeng Xu, Zonglin She. Atrophy of bilateral nucleus accumbens in melancholic depression. Neuroreport. vol 34. issue 10. 2023-06-04. PMID:37270840. |
thus, the current study aimed to explore the structural changes of the subcortical regions among melancholic depression (md) patients, especially in the nac, hippocampus, and amygdala, to provide a theoretical basis for understanding the pathological mechanisms of md. |
2023-06-04 |
2023-08-14 |
human |
| Pablo Martínez San Segundo, Beatrice Terni, Artur Llobe. Multivesicular release favors short term synaptic depression in hippocampal autapses. Frontiers in cellular neuroscience. vol 17. 2023-06-02. PMID:37265578. |
multivesicular release favors short term synaptic depression in hippocampal autapses. |
2023-06-02 |
2023-08-14 |
Not clear |
| Shufang Xia, Gusonghan Maitiniyazi, Yuan Liu, Yue Chen, Mengting Guo, Jianyun He, Wei Tao, Ziyuan L. Whey protein isolate attenuates depression-like behavior developed in a mouse model of breast tumor. Food research international (Ottawa, Ont.). vol 169. 2023-05-31. PMID:37254425. |
our results suggest that wpi exhibits a potent antidepressant-like effect via the regulation of hippocampal trp metabolism and alteration of gm composition and function, and it may be an effective prevention for cancer-related depression. |
2023-05-31 |
2023-08-14 |
mouse |
| Meng Zhang, Li-Yuan Liu, Yong Xu, Wen-Zhi Wang, Nian-Zhuang Qiu, Fang-Fang Zhang, Feng Zhang, Xiao-Dan Wang, Wei Chen, Xiao-Yan Xu, Yong-Feng Gao, Mei-Hua Chen, Yu-Qin Li, Han-Ting Zhang, Hao Wan. Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease. Metabolic brain disease. 2023-05-31. PMID:37256468. |
high-performance liquid chromatography coupled to tandem mass spectrometry (hplc-ms/ms) was used to detect the level of neurotransmitters related to depression in the hippocampus of mice. |
2023-05-31 |
2023-08-14 |
mouse |
| Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li, Lingdong Kon. Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression. Acta pharmaceutica Sinica. B. vol 13. issue 5. 2023-05-30. PMID:37250149. |
neuron stem cell nlrp6 sustains hippocampal neurogenesis to resist stress-induced depression. |
2023-05-30 |
2023-08-14 |
mouse |
| Dimple Shet, Nayanatara Arun Kumar, Megha Gokul, Rekha Durgadas Kini, Aradhana Marathe, Sowndarya Kollampare, Vandana Blosso. Protective role of cod liver oil on hippocampal oxidative damage and neuronal count in Wistar rat model of comorbid depression. Open veterinary journal. vol 13. issue 4. 2023-05-30. PMID:37251260. |
protective role of cod liver oil on hippocampal oxidative damage and neuronal count in wistar rat model of comorbid depression. |
2023-05-30 |
2023-08-14 |
rat |
| Xiao Qiu, Pengcheng Lu, Xinyu Zeng, Shengjie Jin, Xianghe Che. Study on the Mechanism for SIRT1 during the Process of Exercise Improving Depression. Brain sciences. vol 13. issue 5. 2023-05-27. PMID:37239191. |
silent information regulator 1 (sirt1) is a key player in regulating energy metabolism, and it can regulate depression by mediating the inflammatory response (e.g., nuclear factor-kappa b (nf-κb), tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β)), gene expression in the nucleus accumben (nac) and ca1 region of the hippocampus (e.g., nescient helix-loop-helix2 (nhlh2), monoamine oxidase (mao-a), and 5-hydroxyindole-3-acetic acid (5-hiaa)), and neuronal regeneration in the ca3 region of the hippocampus. |
2023-05-27 |
2023-08-14 |
Not clear |