| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Maria Pugliese, Elisabetta Coppi, Rosaria Volpini, Gloria Cristalli, Renato Corradetti, Lak Shin Jeong, Kenneth A Jacobson, Felicita Pedat. Role of adenosine A3 receptors on CA1 hippocampal neurotransmission during oxygen-glucose deprivation episodes of different duration. Biochemical pharmacology. vol 74. issue 5. 2008-04-22. PMID:17626785. |
the novel, selective a3 antagonist lj1251 ((2r,3r,4s)-2-(2-chloro-6-(3-iodobenzylamino)-9h-purin-9-yl)tetrahydrothiophene-3,4-diol, 0.1-10 nm) protected hippocampal slices from irreversible fepsp depression induced by severe ogd and prevented or delayed the appearance of anoxic depolarization. |
2008-04-22 |
2023-08-12 |
rat |
| E M Wexler, D H Geschwind, T D Palme. Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation. Molecular psychiatry. vol 13. issue 3. 2008-04-17. PMID:17968353. |
neural stem cells give rise to new hippocampal neurons throughout adulthood, and defects in neurogenesis may predispose an individual to mood disorders, such as major depression. |
2008-04-17 |
2023-08-12 |
Not clear |
| Pavan K Shetty, Freesia L Huang, Kuo-Ping Huan. Ischemia-elicited oxidative modulation of Ca2+/calmodulin-dependent protein kinase II. The Journal of biological chemistry. vol 283. issue 9. 2008-04-15. PMID:18174165. |
short term ischemia (10 min) caused a depression of basal synaptic response of the hippocampal slices, and re-oxygenation (after 10 min) reversed the depression. |
2008-04-15 |
2023-08-12 |
mouse |
| Shannon N Lenze, Chengjie Xiong, Yvette I Shelin. Childhood adversity predicts earlier onset of major depression but not reduced hippocampal volume. Psychiatry research. vol 162. issue 1. 2008-04-08. PMID:18068956. |
childhood adversity predicts earlier onset of major depression but not reduced hippocampal volume. |
2008-04-08 |
2023-08-12 |
Not clear |
| Shannon N Lenze, Chengjie Xiong, Yvette I Shelin. Childhood adversity predicts earlier onset of major depression but not reduced hippocampal volume. Psychiatry research. vol 162. issue 1. 2008-04-08. PMID:18068956. |
this study examined the relationship between childhood adversity, hippocampal volumes and clinical characteristics in women who were recruited for depression history rather than abuse experiences. |
2008-04-08 |
2023-08-12 |
Not clear |
| Shannon N Lenze, Chengjie Xiong, Yvette I Shelin. Childhood adversity predicts earlier onset of major depression but not reduced hippocampal volume. Psychiatry research. vol 162. issue 1. 2008-04-08. PMID:18068956. |
further research is needed to more fully understand the interrelationships among childhood adversity, hippocampal morphology, neuroendocrine regulation, and other genetic and environmental factors influencing vulnerability to depression. |
2008-04-08 |
2023-08-12 |
Not clear |
| Megumi Adachi, Michel Barrot, Anita E Autry, David Theobald, Lisa M Monteggi. Selective loss of brain-derived neurotrophic factor in the dentate gyrus attenuates antidepressant efficacy. Biological psychiatry. vol 63. issue 7. 2008-04-03. PMID:17981266. |
the neurotrophic hypothesis of depression suggests that loss of bdnf from the hippocampus contributes to an increased vulnerability for depression, whereas upregulation of bdnf in the hippocampus is suggested to mediate antidepressant efficacy. |
2008-04-03 |
2023-08-12 |
Not clear |
| Y S Mineur, C Belzung, W E Crusi. Functional implications of decreases in neurogenesis following chronic mild stress in mice. Neuroscience. vol 150. issue 2. 2008-04-03. PMID:17981399. |
numerous data from human and animal studies suggest that hippocampal plasticity might be a key element in depression. |
2008-04-03 |
2023-08-12 |
mouse |
| Martina Ballmaier, Katherine L Narr, Arthur W Toga, Virginia Elderkin-Thompson, Paul M Thompson, Liberty Hamilton, Ebrahim Haroon, Daniel Pham, Andreas Heinz, Anand Kuma. Hippocampal morphology and distinguishing late-onset from early-onset elderly depression. The American journal of psychiatry. vol 165. issue 2. 2008-03-24. PMID:17986679. |
hippocampal morphology and distinguishing late-onset from early-onset elderly depression. |
2008-03-24 |
2023-08-12 |
Not clear |
| Martina Ballmaier, Katherine L Narr, Arthur W Toga, Virginia Elderkin-Thompson, Paul M Thompson, Liberty Hamilton, Ebrahim Haroon, Daniel Pham, Andreas Heinz, Anand Kuma. Hippocampal morphology and distinguishing late-onset from early-onset elderly depression. The American journal of psychiatry. vol 165. issue 2. 2008-03-24. PMID:17986679. |
this study used three-dimensional mapping techniques to identify regional hippocampal abnormalities in early- and late-onset depression. |
2008-03-24 |
2023-08-12 |
Not clear |
| Tyson B Brust, Francisco S Cayabyab, Brian A MacVica. C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:17967469. |
c-jun n-terminal kinase regulates adenosine a1 receptor-mediated synaptic depression in the rat hippocampus. |
2008-03-21 |
2023-08-12 |
rat |
| Tyson B Brust, Francisco S Cayabyab, Brian A MacVica. C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus. Neuropharmacology. vol 53. issue 8. 2008-03-21. PMID:17967469. |
we tested the contribution of c-jun n-terminal kinase (jnk) to adenosine a1 receptor-mediated depression of field excitatory postsynaptic potentials (fepsps) in area ca1 of the rat hippocampus. |
2008-03-21 |
2023-08-12 |
rat |
| Alexander Kulla, Denise Manahan-Vaugha. Modulation by group 1 metabotropic glutamate receptors of depotentiation in the dentate gyrus of freely moving rats. Hippocampus. vol 18. issue 1. 2008-03-18. PMID:17924526. |
in the hippocampus, synaptic depression of potentiated synapses in the form of depotentiation, or of naive synapses in the form of long-term depression (ltd) is mediated by distinct molecular mechanisms. |
2008-03-18 |
2023-08-12 |
rat |
| Clive R Bramha. Control of synaptic consolidation in the dentate gyrus: mechanisms, functions, and therapeutic implications. Progress in brain research. vol 163. 2008-03-14. PMID:17765733. |
this chapter focuses on the mechanisms and functions of synaptic consolidation in the dentate gyrus, a critical structure not only in hippocampal memory function, but also in regulation of stress responses and cognitive aspects of depression. |
2008-03-14 |
2023-08-12 |
rat |
| Amar Sahay, Michael R Drew, Rene He. Dentate gyrus neurogenesis and depression. Progress in brain research. vol 163. 2008-03-14. PMID:17765746. |
while an involvement of neurogenesis in the etiology of depression remains highly speculative, preclinical studies have revealed a novel and previously unrecognized role for hippocampal neurogenesis in mediating some of the behavioral effects of antidepressants. |
2008-03-14 |
2023-08-12 |
Not clear |
| J V Negrete-Díaz, T S Sihra, J M Delgado-García, A Rodríguez-Moren. Kainate receptor-mediated presynaptic inhibition converges with presynaptic inhibition mediated by Group II mGluRs and long-term depression at the hippocampal mossy fiber-CA3 synapse. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 11. 2008-03-11. PMID:17510730. |
kainate receptors (kars) effect depression of glutamate release at hippocampal mossy fiber-ca3 (mf-ca3) synapses by a metabotropic action involving adenylyl cyclase (ac) inhibition, camp reduction, and diminished protein kinase a (pka) activation. |
2008-03-11 |
2023-08-12 |
Not clear |
| J V Negrete-Díaz, T S Sihra, J M Delgado-García, A Rodríguez-Moren. Kainate receptor-mediated presynaptic inhibition converges with presynaptic inhibition mediated by Group II mGluRs and long-term depression at the hippocampal mossy fiber-CA3 synapse. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 11. 2008-03-11. PMID:17510730. |
using hippocampal slices, we show here that kar activation interferes with the depression of glutamate release produced by group ii metabotropic glutamate receptor stimulation and low frequency stimulation (lfs)-induced long-term depression (ltd), also expressed through presynaptic ac/camp/pka at mf-ca3 synapses. |
2008-03-11 |
2023-08-12 |
Not clear |
| A B Marcussen, P Flagstad, P E G Kristjansen, F F Johansen, U Englun. Increase in neurogenesis and behavioural benefit after chronic fluoxetine treatment in Wistar rats. Acta neurologica Scandinavica. vol 117. issue 2. 2008-03-03. PMID:18184344. |
disturbances in hippocampal neurogenesis may be involved in the pathophysiology of depression and it has been argued that an increase in the generation of new nerve cells in the hippocampus is involved in the mechanism of action of antidepressants. |
2008-03-03 |
2023-08-12 |
rat |
| My Andersson, Fredrik Blomstrand, Eric Hans. Astrocytes play a critical role in transient heterosynaptic depression in the rat hippocampal CA1 region. The Journal of physiology. vol 585. issue Pt 3. 2008-02-25. PMID:17962333. |
in the present study we have examined the developmental profile and astrocytic involvement in a transient heterosynaptic depression (thesd) in the ca1 region of the rat hippocampal slice preparation. |
2008-02-25 |
2023-08-12 |
rat |
| Robert Wöhrl, Sven Eisenach, Denise Manahan-Vaughan, Uwe Heinemann, Dorothea von Haeble. Acute and long-term effects of MK-801 on direct cortical input evoked homosynaptic and heterosynaptic plasticity in the CA1 region of the female rat. The European journal of neuroscience. vol 26. issue 10. 2008-02-25. PMID:18001284. |
we analysed acute and long-term effects of the n-methyl-d-aspartate receptor antagonist mk-801 on long-term heterosynaptic population spike depression (lthpsd) evoked by high-frequency stimulation of the direct cortical input in female rat hippocampal slices to understand disturbances in cognitive functions associated with an acute phencyclidine-induced psychosis. |
2008-02-25 |
2023-08-12 |
rat |