| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer Keller, Lin Shen, Rowena G Gomez, Amy Garrett, H Brent Solvason, Allan Reiss, Alan F Schatzber. Hippocampal and amygdalar volumes in psychotic and nonpsychotic unipolar depression. The American journal of psychiatry. vol 165. issue 7. 2008-08-01. PMID:18450931. |
the purpose of the present study was to examine differences in hippocampal and amygdalar volumes in patients with depression subtypes relative to healthy comparison subjects. |
2008-08-01 |
2023-08-12 |
human |
| I G Sil'ki. The role of dopamine-dependent negative feedback in the hippocampus-basal ganglia-thalamus-hippocampus loop in the extinction of responses. Neuroscience and behavioral physiology. vol 38. issue 4. 2008-07-24. PMID:18401733. |
however, increases in dopamine levels and activation of d2 receptors on striopallidal cells, facilitating depression of hippocampal inputs, prevent disinhibition of dopaminergic neurons, such that their responses start to decline. |
2008-07-24 |
2023-08-12 |
Not clear |
| Ilse Smolders, Ralph Clinckers, Alfred Meurs, Dimitri De Bundel, Jeanelle Portelli, Guy Ebinger, Yvette Michott. Direct enhancement of hippocampal dopamine or serotonin levels as a pharmacodynamic measure of combined antidepressant-anticonvulsant action. Neuropharmacology. vol 54. issue 6. 2008-07-22. PMID:18378264. |
a key role for limbic monoamines in depression has been established and we recently showed the importance of hippocampal monoamines in limbic seizure control. |
2008-07-22 |
2023-08-12 |
mouse |
| R Silva, A R Mesquita, J Bessa, J C Sousa, I Sotiropoulos, P Leão, O F X Almeida, N Sous. Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3beta. Neuroscience. vol 152. issue 3. 2008-07-21. PMID:18291594. |
although the mechanisms implicated in the genesis of mood disorders are still unclear, stress is known to predispose to depression, and recently, studies have related hippocampal neurogenesis and apoptosis to depression. |
2008-07-21 |
2023-08-12 |
rat |
| Clotilde Lauro, Silvia Di Angelantonio, Raffaela Cipriani, Fabrizia Sobrero, Letizia Antonilli, Valentina Brusadin, Davide Ragozzino, Cristina Limatol. Activity of adenosine receptors type 1 Is required for CX3CL1-mediated neuroprotection and neuromodulation in hippocampal neurons. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 11. 2008-07-18. PMID:18490761. |
similarly, experiments from whole-cell patch-clamped hippocampal neurons in culture, obtained from cx(3)cr1(+/+) mice, show that cx(3)cl1-induced depression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid- (ampa-) type glu receptor-mediated current (ampa-current), is associated with ar(1) activity being blocked by dpcpx and mimicked by adenosine. |
2008-07-18 |
2023-08-12 |
mouse |
| Clotilde Lauro, Silvia Di Angelantonio, Raffaela Cipriani, Fabrizia Sobrero, Letizia Antonilli, Valentina Brusadin, Davide Ragozzino, Cristina Limatol. Activity of adenosine receptors type 1 Is required for CX3CL1-mediated neuroprotection and neuromodulation in hippocampal neurons. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 11. 2008-07-18. PMID:18490761. |
furthermore, bv2-st medium induced a similar ampa-current depression in cx(3)cr1(gfp/gfp) hippocampal neurons and this depression was again blocked by dpcpx. |
2008-07-18 |
2023-08-12 |
mouse |
| A-M Bao, G Meynen, D F Swaa. The stress system in depression and neurodegeneration: focus on the human hypothalamus. Brain research reviews. vol 57. issue 2. 2008-07-01. PMID:17524488. |
this 'glucocorticoid cascade hypothesis' of stress and hippocampal damage was proposed to be causally involved in age-related accumulation of hippocampal damage in disorders like alzheimer's disease and depression. |
2008-07-01 |
2023-08-12 |
human |
| Shao-hua Wang, Zhi-jun Zhang, Yi-jing Guo, Gao-jun Teng, Bao-an Che. Hippocampal neurogenesis and behavioural studies on adult ischemic rat response to chronic mild stress. Behavioural brain research. vol 189. issue 1. 2008-07-01. PMID:18258314. |
stress and antidepressants have been shown to influence hippocampal neurogenesis, which is hypothesized to be an etiological factor of depression. |
2008-07-01 |
2023-08-12 |
rat |
| Philip Gorwood, Emmanuelle Corruble, Bruno Falissard, Guy M Goodwi. Toxic effects of depression on brain function: impairment of delayed recall and the cumulative length of depressive disorder in a large sample of depressed outpatients. The American journal of psychiatry. vol 165. issue 6. 2008-06-25. PMID:18381906. |
an important current hypothesis suggests that the relationship between severe depression and the hippocampus is essentially toxic. |
2008-06-25 |
2023-08-12 |
Not clear |
| Philip Gorwood, Emmanuelle Corruble, Bruno Falissard, Guy M Goodwi. Toxic effects of depression on brain function: impairment of delayed recall and the cumulative length of depressive disorder in a large sample of depressed outpatients. The American journal of psychiatry. vol 165. issue 6. 2008-06-25. PMID:18381906. |
the purpose of this study was to assess the generalizability of the impact of depression on hippocampal function. |
2008-06-25 |
2023-08-12 |
Not clear |
| Hideki Miura, Norio Ozaki, Makoto Sawada, Kenichi Isobe, Tatsuro Ohta, Toshiharu Nagats. A link between stress and depression: shifts in the balance between the kynurenine and serotonin pathways of tryptophan metabolism and the etiology and pathophysiology of depression. Stress (Amsterdam, Netherlands). vol 11. issue 3. 2008-06-19. PMID:18465467. |
the hippocampal atrophy that appears in chronic depression may be associated with imbalances in neurotoxic/neuroprotective activities. |
2008-06-19 |
2023-08-12 |
Not clear |
| Elizabeth Garcia-Perez, John F Wesselin. Augmentation controls the fast rebound from depression at excitatory hippocampal synapses. Journal of neurophysiology. vol 99. issue 4. 2008-06-17. PMID:18199812. |
augmentation controls the fast rebound from depression at excitatory hippocampal synapses. |
2008-06-17 |
2023-08-12 |
Not clear |
| Dan Wang, Shu Cheng An, Xia Zhan. Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor. Neuroscience letters. vol 433. issue 1. 2008-06-02. PMID:18248896. |
thus, inhibition of hippocampal inos may prevent the development of cums model of depression. |
2008-06-02 |
2023-08-12 |
Not clear |
| Fraser Murray, David W Smith, Peter H Hutso. Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice. European journal of pharmacology. vol 583. issue 1. 2008-05-27. PMID:18289522. |
chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice. |
2008-05-27 |
2023-08-12 |
mouse |
| Fraser Murray, David W Smith, Peter H Hutso. Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice. European journal of pharmacology. vol 583. issue 1. 2008-05-27. PMID:18289522. |
we have compared the effects of chronic and acute corticosterone administration on hippocampal cell proliferation (as measured by brdu immunohistochemistry), hippocampal volume and the appearance of anxiety (light dark box) and depression (forced swim test) like behaviours in cd1 mice. |
2008-05-27 |
2023-08-12 |
mouse |
| Michael A Rapp, Michal Schnaider-Beeri, Dushyant P Purohit, Daniel P Perl, Vahram Haroutunian, Mary San. Increased neurofibrillary tangles in patients with Alzheimer disease with comorbid depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 16. issue 2. 2008-05-14. PMID:18239198. |
recent evidence suggests that a history of major depression may lead to increases in hippocampal neuropathology in alzheimer disease (ad). |
2008-05-14 |
2023-08-12 |
Not clear |
| Fan Lu, Hong-mei Zhu, Jun-jie Xie, Hai-hong Zhou, Yan-ling Chen, Ji-yuan H. [Effects of electroacupuncture on behavior, plasma COR and expressions of PKA and PKC in hippocampus of the depression model rat]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 28. issue 3. 2008-05-13. PMID:18447224. |
[effects of electroacupuncture on behavior, plasma cor and expressions of pka and pkc in hippocampus of the depression model rat]. |
2008-05-13 |
2023-08-12 |
rat |
| Vladyslav V Vyazovskiy, Chiara Cirelli, Martha Pfister-Genskow, Ugo Faraguna, Giulio Tonon. Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep. Nature neuroscience. vol 11. issue 2. 2008-05-08. PMID:18204445. |
we show that, in rat cortex and hippocampus, glur1-containing ampa receptor (ampar) levels are high during wakefulness and low during sleep, and changes in the phosphorylation states of ampars, camkii and gsk3beta are consistent with synaptic potentiation during wakefulness and depression during sleep. |
2008-05-08 |
2023-08-12 |
rat |
| Hiroki Yasuda, Yan Huang, Tadaharu Tsumot. Regulation of excitability and plasticity by endocannabinoids and PKA in developing hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 8. 2008-04-29. PMID:18287074. |
in the hippocampus older than p6 (p > 6), however, ltp is protected from ecb-mediated depression by pka activated at presynaptic sites by high-frequency stimulation, serving to highlight pka-mediated ltp by weakening inactive synapses even in adjacent cells. |
2008-04-29 |
2023-08-12 |
Not clear |
| Long-Hua Zhang, Neng Gong, Da Fei, Lin Xu, Tian-Le X. Glycine uptake regulates hippocampal network activity via glycine receptor-mediated tonic inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 3. 2008-04-23. PMID:17522628. |
these results indicate an essential role of glyts in fine-tuning tonic activation of glyrs and suggest a potential role of glyr-dependent epsp-spike depression in hippocampal network stability. |
2008-04-23 |
2023-08-12 |
Not clear |