| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lintao Qu, L Stan Leun. Mechanisms of hyperthermia-induced depression of GABAergic synaptic transmission in the immature rat hippocampus. Journal of neurochemistry. vol 106. issue 5. 2008-11-03. PMID:18643787. |
mechanisms of hyperthermia-induced depression of gabaergic synaptic transmission in the immature rat hippocampus. |
2008-11-03 |
2023-08-12 |
rat |
| Lintao Qu, L Stan Leun. Mechanisms of hyperthermia-induced depression of GABAergic synaptic transmission in the immature rat hippocampus. Journal of neurochemistry. vol 106. issue 5. 2008-11-03. PMID:18643787. |
we previously demonstrated that hyperthermia produced a depression of gabaergic neurotransmission in the hippocampus of immature rats in vitro. |
2008-11-03 |
2023-08-12 |
rat |
| Wei Wang, Zhi Zhang, Jing Shang, Zhen-Zhou Jiang, Shu Wang, Yong Liu, Lu-Yong Zhan. Activation of group I metabotropic glutamate receptors induces long-term depression in the hippocampal CA1 region of adult rats in vitro. Neuroscience research. vol 62. issue 1. 2008-10-24. PMID:18602428. |
however, this synaptic depression could be completely abolished by application of metabotropic glutamate receptor (mglur) antagonist (s)-amethyl-4-carboxyphenylglycine (mcpg) which had no effect on that induced by the same protocol in the 16-day-old rat hippocampus. |
2008-10-24 |
2023-08-12 |
rat |
| Stephen Michael Taylo. Electroconvulsive therapy, brain-derived neurotrophic factor, and possible neurorestorative benefit of the clinical application of electroconvulsive therapy. The journal of ECT. vol 24. issue 2. 2008-10-21. PMID:18580563. |
hippocampal volumes are correlated with decreased expression of neurotrophic factors (most notably, brain-derived neurotrophic factor [bdnf]), and decreased expression of bdnf correlates with the presence of depression. |
2008-10-21 |
2023-08-12 |
Not clear |
| Zeng-You Ye, Ke-Qing Zhou, Tian-Le Xu, Jiang-Ning Zho. Fluoxetine potentiates GABAergic IPSCs in rat hippocampal neurons. Neuroscience letters. vol 442. issue 1. 2008-10-14. PMID:18606211. |
this potentiation by fluoxetine may normalize the hippocampal gaba deficit during depression and in part exert its antidepressant activity. |
2008-10-14 |
2023-08-12 |
rat |
| I G Sil'ki. [Characteristics of the hippocampal formation functioning during wakefulness and paradoxical sleep]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 58. issue 3. 2008-10-10. PMID:18689238. |
in view of the available published data concerning various concentration of neuromodulators in the brain during paradoxical sleep and wakefulness and the evidence for the influences of neuromodulators on efficiency of synaptic inputs to hippocampal neurons it is concluded that during paradoxical sleep, increase in concentrations of acetylcholine, cortisol, and dopamine and simultaneous decrease in serotonin and noradrenaline levels could synergistically lead to essential depression of efficacy of synaptic transmission in the polysynaptic pathway through the hippocampus (i.e. |
2008-10-10 |
2023-08-12 |
Not clear |
| Benedikt Römer, Alexander Sartorius, Dragos Inta, Barbara Vollmayr, Peter Gas. Imaging new neurons in vivo: a pioneering tool to study the cellular biology of depression? BioEssays : news and reviews in molecular, cellular and developmental biology. vol 30. issue 9. 2008-10-09. PMID:18693259. |
hippocampal neurogenesis has been implicated in the pathogenesis of and recovery from depression. |
2008-10-09 |
2023-08-12 |
human |
| Christine Heim, D Jeffrey Newport, Tanja Mletzko, Andrew H Miller, Charles B Nemerof. The link between childhood trauma and depression: insights from HPA axis studies in humans. Psychoneuroendocrinology. vol 33. issue 6. 2008-10-08. PMID:18602762. |
we here summarize results from a series of clinical studies suggesting that childhood trauma in humans is associated with sensitization of the neuroendocrine stress response, glucocorticoid resistance, increased central corticotropin-releasing factor (crf) activity, immune activation, and reduced hippocampal volume, closely paralleling several of the neuroendocrine features of depression. |
2008-10-08 |
2023-08-12 |
Not clear |
| Natalie C Tronson, Christina Schrick, Andre Fischer, Farahnaz Sananbenesi, Gilles Pagès, Jacques Pouysségur, Jelena Radulovi. Regulatory mechanisms of fear extinction and depression-like behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 7. 2008-09-24. PMID:17712345. |
both behaviors were reversed by inhibition of mek, however the extinction phenotype depended on hippocampal, whereas the depression phenotype predominantly involved extrahippocampal mek. |
2008-09-24 |
2023-08-12 |
mouse |
| b' M P\\xc3\\xa1v, H Kov\\xc3\\xa1\\xc5\\x99\\xc5\\xaf, A Fi\\xc5\\xa1erov\\xc3\\xa1, E Havrdov\\xc3\\xa1, V Lis\\xc3\\xa. Neurobiological aspects of depressive disorder and antidepressant treatment: role of glia. Physiological research. vol 57. issue 2. 2008-09-17. PMID:17465696.' |
depression is a complex disorder related to chronic inflammatory processes, chronic stress changes and a hippocampal response. |
2008-09-17 |
2023-08-12 |
Not clear |
| Natalia Onishchenko, Nina Karpova, Farideh Sabri, Eero Castrén, Sandra Ceccatell. Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18485098. |
our study shows that developmental exposure to low levels of mehg predisposes mice to depression and induces epigenetic suppression of bdnf gene expression in the hippocampus. |
2008-09-15 |
2023-08-12 |
mouse |
| Klaus-Thomas Kronmüller, Johannes Pantel, Sebastian Köhler, Daniela Victor, Frederik Giesel, Vincent A Magnotta, Christoph Mundt, Marco Essig, Johannes Schröde. Hippocampal volume and 2-year outcome in depression. The British journal of psychiatry : the journal of mental science. vol 192. issue 6. 2008-09-15. PMID:18515903. |
hippocampal volume and 2-year outcome in depression. |
2008-09-15 |
2023-08-12 |
Not clear |
| Klaus-Thomas Kronmüller, Johannes Pantel, Sebastian Köhler, Daniela Victor, Frederik Giesel, Vincent A Magnotta, Christoph Mundt, Marco Essig, Johannes Schröde. Hippocampal volume and 2-year outcome in depression. The British journal of psychiatry : the journal of mental science. vol 192. issue 6. 2008-09-15. PMID:18515903. |
we investigated hippocampal volume (using high-resolution magnetic resonance imaging) and 2-year outcome in 57 patients with major depression. |
2008-09-15 |
2023-08-12 |
Not clear |
| Klaus-Thomas Kronmüller, Johannes Pantel, Sebastian Köhler, Daniela Victor, Frederik Giesel, Vincent A Magnotta, Christoph Mundt, Marco Essig, Johannes Schröde. Hippocampal volume and 2-year outcome in depression. The British journal of psychiatry : the journal of mental science. vol 192. issue 6. 2008-09-15. PMID:18515903. |
the left and right hippocampal volumes of patients with a depression relapse were significantly smaller than those of healthy controls. |
2008-09-15 |
2023-08-12 |
Not clear |
| Klaus-Thomas Kronmüller, Johannes Pantel, Sebastian Köhler, Daniela Victor, Frederik Giesel, Vincent A Magnotta, Christoph Mundt, Marco Essig, Johannes Schröde. Hippocampal volume and 2-year outcome in depression. The British journal of psychiatry : the journal of mental science. vol 192. issue 6. 2008-09-15. PMID:18515903. |
our results support the hypothesis that the hippocampus is crucial in the outcome of depression. |
2008-09-15 |
2023-08-12 |
Not clear |
| D D Luo, S C An, X Zhan. Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress. Brain research bulletin. vol 77. issue 1. 2008-09-11. PMID:18579108. |
involvement of hippocampal serotonin and neuropeptide y in depression induced by chronic unpredicted mild stress. |
2008-09-11 |
2023-08-12 |
rat |
| D D Luo, S C An, X Zhan. Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress. Brain research bulletin. vol 77. issue 1. 2008-09-11. PMID:18579108. |
accumulated evidence indicates a role of the hippocampal 5-hydroxy-tryptamine (5-ht) and neuropeptide y (npy) in the response to stress and modulation of depression, but it is unclear whether and how the hippocampal 5-ht and npy systems make contributions to chronic unpredicted mild stress (cums)-induced depression. |
2008-09-11 |
2023-08-12 |
rat |
| D D Luo, S C An, X Zhan. Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress. Brain research bulletin. vol 77. issue 1. 2008-09-11. PMID:18579108. |
these data suggest a critical role of reduced hippocampal 5-ht and npy neurotransmission in cums-induced depression. |
2008-09-11 |
2023-08-12 |
rat |
| Ilan Halperin, Amos D Korczy. [Depression precedes development of dementia]. Harefuah. vol 147. issue 4. 2008-09-04. PMID:18686817. |
dementia and depression show many common biologic features such as white matter changes in the brain, reduction of hippocampus volume, changes in the serotonergic and noradrenalinergic systems and abnormalities in the hypothalamic-pituitary-adrenal axis. |
2008-09-04 |
2023-08-12 |
Not clear |
| Analía Reinés, Marina Cereseto, Alejandro Ferrero, Laura Sifonios, Maria Fernanda Podestá, Silvia Wikinsk. Maintenance treatment with fluoxetine is necessary to sustain normal levels of synaptic markers in an experimental model of depression: correlation with behavioral response. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 8. 2008-09-02. PMID:17955054. |
dysfunction of hippocampal plasticity has been proposed to play a critical role in the pathophysiology of depression. |
2008-09-02 |
2023-08-12 |
Not clear |