| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dora Kanellopoulos, Faith M Gunning, Sarah S Morimoto, Matthew J Hoptman, Christopher F Murphy, Robert E Kelly, Charles Glatt, Kelvin O Lim, George S Alexopoulo. Hippocampal volumes and the brain-derived neurotrophic factor val66met polymorphism in geriatric major depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 19. issue 1. 2011-04-08. PMID:21218562. |
hippocampal volumes and the brain-derived neurotrophic factor val66met polymorphism in geriatric major depression. |
2011-04-08 |
2023-08-12 |
Not clear |
| Daisuke Okajima, Gen Kudo, Hiroshi Yokot. Antidepressant-like behavior in brain-specific angiogenesis inhibitor 2-deficient mice. The journal of physiological sciences : JPS. vol 61. issue 1. 2011-04-07. PMID:21110148. |
these results indicate that bai2 has an important role related to depression and influences the hippocampal neurogenesis. |
2011-04-07 |
2023-08-12 |
mouse |
| Marcella Bellani, Monica Baiano, Paolo Brambill. Brain anatomy of major depression I. Focus on hippocampus. Epidemiologia e psichiatria sociale. vol 19. issue 4. 2011-04-06. PMID:21322503. |
here we briefly summarize the most consistent structural mri studies on hippocampus in major depression and debate the effects of clinical variables on hippocampal morphology. |
2011-04-06 |
2023-08-12 |
Not clear |
| Philip van Eijndhoven, Guido van Wingen, Guillén Fernández, Mark Rijpkema, Robbert Jan Verkes, Jan Buitelaar, Indira Tendolka. Amygdala responsivity related to memory of emotionally neutral stimuli constitutes a trait factor for depression. NeuroImage. vol 54. issue 2. 2011-04-05. PMID:20800687. |
episodic memory impairment is considered to be a core cognitive deficit of major depressive disorder (mdd) and has motivated a line of research investigating the role of the amygdala and the hippocampus in depression. |
2011-04-05 |
2023-08-12 |
human |
| Francesca Galeffi, George G Somjen, Kelley A Foster, Dennis A Turne. Simultaneous monitoring of tissue PO2 and NADH fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 2. 2011-03-17. PMID:20736960. |
simultaneous monitoring of tissue po2 and nadh fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices. |
2011-03-17 |
2023-08-12 |
rat |
| Susanne Brummelte, Liisa A M Gale. Chronic corticosterone during pregnancy and postpartum affects maternal care, cell proliferation and depressive-like behavior in the dam. Hormones and behavior. vol 58. issue 5. 2011-03-08. PMID:20688070. |
thus prolonged treatment with high levels of cort postpartum reduced maternal care, hippocampal cell proliferation and induced depressive-like behavior in the dam and therefore might be considered an animal model of postpartum depression. |
2011-03-08 |
2023-08-12 |
Not clear |
| Fenghua Chen, Torsten M Madsen, Gregers Wegener, Jens R Nyengaar. Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression. Hippocampus. vol 20. issue 12. 2011-03-07. PMID:19921703. |
imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression. |
2011-03-07 |
2023-08-12 |
rat |
| Robbert G E Notenboom, Geert M J Ramakers, Amer Kamal, Berry M Spruijt, Pierre N E de Graa. Long-lasting modulation of synaptic plasticity in rat hippocampus after early-life complex febrile seizures. The European journal of neuroscience. vol 32. issue 5. 2011-03-01. PMID:20646062. |
we examined three specific measures of hippocampal plasticity in adult rats with a prior history of experimental febrile seizures: (i) activity-dependent synaptic plasticity (long-term potentiation and depression) by electrophysiological recordings of schaffer collateral/commissural-evoked field excitatory synaptic potentials in ca1 of acute hippocampal slices; (ii) morris water maze spatial learning and memory; and (iii) hippocampal mossy fiber plasticity by timm histochemistry and quantification of terminal sprouting in ca3 and the dentate gyrus. |
2011-03-01 |
2023-08-12 |
human |
| Wei Dai, Wei-Dong Li, Jun L. [Effect of electroacupuncture on hippocampal apoptosis and JNK signal pathway in chronic stress depression rats]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 5. 2011-02-24. PMID:21235059. |
[effect of electroacupuncture on hippocampal apoptosis and jnk signal pathway in chronic stress depression rats]. |
2011-02-24 |
2023-08-12 |
rat |
| Wei Dai, Wei-Dong Li, Jun L. [Effect of electroacupuncture on hippocampal apoptosis and JNK signal pathway in chronic stress depression rats]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 5. 2011-02-24. PMID:21235059. |
to observe the effect of electroacupuncture (ea) on hippocampal apoptosis and c-jun n-terminal kinase (jnk) signal pathway in chronic stress depression rats so as to study its mechanism underlying acupuncture-induced improvement of depression. |
2011-02-24 |
2023-08-12 |
rat |
| Zang-Hee Cho, Young-Bo Kim, Jae-Yong Han, Nam-Beom Kim, Seok-Il Hwang, Seog Ju Kim, Seong-Jin Ch. Altered T2* relaxation time of the hippocampus in major depressive disorder: implications of ultra-high field magnetic resonance imaging. Journal of psychiatric research. vol 44. issue 14. 2011-02-02. PMID:20338580. |
these findings suggest that region-specific hippocampal damage may be occurring in recurrent depression. |
2011-02-02 |
2023-08-12 |
human |
| Y C Ho, S Wan. Adult neurogenesis is reduced in the dorsal hippocampus of rats displaying learned helplessness behavior. Neuroscience. vol 171. issue 1. 2011-02-02. PMID:20816923. |
clinical and preclinical studies suggest that the hippocampus has a role in the pathophysiology of major depression. |
2011-02-02 |
2023-08-12 |
rat |
| Y C Ho, S Wan. Adult neurogenesis is reduced in the dorsal hippocampus of rats displaying learned helplessness behavior. Neuroscience. vol 171. issue 1. 2011-02-02. PMID:20816923. |
in the learned helplessness (lh) animal model of depression after inescapable shocks (iss) animals that display lh behavior have reduced cell proliferation in the hippocampus; this effect can be reversed by antidepressant treatment. |
2011-02-02 |
2023-08-12 |
rat |
| Betina Elfving, Pia Høgh Plougmann, Heidi Kaastrup Müller, Aleksander A Mathé, Raben Rosenberg, Gregers Wegene. Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796445. |
in investigations between flinders sensitive line (fsl) and flinders resistant line (frl) rats, a genetic rat model of depression, no differences were found in bdnf levels in the frontal cortex and hippocampus, areas believed to be core brain regions in depression. |
2011-01-25 |
2023-08-12 |
human |
| Betina Elfving, Pia Høgh Plougmann, Heidi Kaastrup Müller, Aleksander A Mathé, Raben Rosenberg, Gregers Wegene. Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796445. |
the differential regulation of the bdnf levels in hippocampus, serum, and whole blood in fsl/frl rats adds to the hypothesis that neurotrophic factors are related to the pathophysiology of depression. |
2011-01-25 |
2023-08-12 |
human |
| Hua-Cheng Yan, Hong-Da Qu, Li-Rong Sun, Shu-Ji Li, Xiong Cao, Ying-Ying Fang, Wei Jie, Jonathan C Bean, Wei-Kang Wu, Xin-Hong Zhu, Tian-Ming Ga. Fuzi polysaccharide-1 produces antidepressant-like effects in mice. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796446. |
finally, acute treatment with fps had no effect on brain monoamine levels in frontal cortex but significantly increases bdnf in the hippocampus, while the antidepressant effect and enhancement of cell proliferation induced by fps administration were totally blocked by k252a, an inhibitor of trkb in a chronic social defeat depression model, suggesting that the neurogenic and antidepressant effects of fps may involve bdnf signalling. |
2011-01-25 |
2023-08-12 |
mouse |
| Astrid Zobel, Anna Schuhmacher, Frank Jessen, Susanne Höfels, Olrik von Widdern, Martin Metten, Ute Pfeiffer, Claudia Hanses, Tim Becker, Marcella Rietschel, Lukas Scheef, Wolfgang Block, Hans H Schild, Wolfgang Maier, Sibylle G Schwa. DNA sequence variants of the FKBP5 gene are associated with unipolar depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:20047716. |
in addition, we explored association with treatment response by (a) the hamilton depression rating scale and (b) the dexamethasone/corticotrophin-releasing hormone (dex/crh) test, as well as association with hippocampal volumes in a subpopulation of 110 patients. |
2011-01-25 |
2023-08-12 |
Not clear |
| K A Baranova, E A Rybnikova, V I Mironova, M O Samoilo. Effects of hypoxic preconditioning on expression of transcription factor NGFI-A in the rat brain after unavoidable stress in the "learned helplessness" model. Neuroscience and behavioral physiology. vol 40. issue 6. 2011-01-24. PMID:20535567. |
in rats subjected to three sessions of preconditioning consisting of moderate hypobaric hypoxia (360 mmhg, 2 h, with intervals of 24 h), which did not form depression in these circumstances, there were significant changes in the dynamics of immunoreactive protein content in the hippocampus, with a stable increase in expression in the ventral hippocampus and only transient and delayed (by five days) expression in field ca1. |
2011-01-24 |
2023-08-12 |
rat |
| Denis J David, Jingwen Wang, Benjamin Adam Samuels, Quentin Rainer, Indira David, Alain M Gardier, René He. Implications of the functional integration of adult-born hippocampal neurons in anxiety-depression disorders. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 16. issue 5. 2011-01-21. PMID:20889967. |
adult neurogenesis in the dentate gyrus of the hippocampus has gained considerable attention as a cellular substrate for both the pathophysiology and treatment of depression. |
2011-01-21 |
2023-08-12 |
mouse |
| Denis J David, Jingwen Wang, Benjamin Adam Samuels, Quentin Rainer, Indira David, Alain M Gardier, René He. Implications of the functional integration of adult-born hippocampal neurons in anxiety-depression disorders. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 16. issue 5. 2011-01-21. PMID:20889967. |
we also discuss how adult hippocampal neurogenesis could be involved in affective state disorders such as depression and anxiety. |
2011-01-21 |
2023-08-12 |
mouse |