| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| William F C Baaré, Maj Vinberg, Gitte M Knudsen, Olaf B Paulson, Annika R Langkilde, Terry L Jernigan, Lars Vedel Kessin. Hippocampal volume changes in healthy subjects at risk of unipolar depression. Journal of psychiatric research. vol 44. issue 10. 2010-10-25. PMID:20096419. |
in conclusion, hippocampal volume reduction may index a predisposition to develop depression and thus may be predictive of future onset of the disorder. |
2010-10-25 |
2023-08-12 |
human |
| Eleni Païzanis, Thibault Renoir, Vincent Lelievre, Françoise Saurini, Maxette Melfort, Cecilia Gabriel, Nicholas Barden, Elisabeth Mocaër, Michel Hamon, Laurence Lanfume. Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice. The international journal of neuropsychopharmacology. vol 13. issue 6. 2010-09-29. PMID:19775499. |
major depression is associated with reduced hippocampal volume linked to stress and high glucocorticoid secretion. |
2010-09-29 |
2023-08-12 |
mouse |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Stefan Bren\\xc3\\xa. The antidepressant effects of running and escitalopram are associated with levels of hippocampal NPY and Y1 receptor but not cell proliferation in a rat model of depression. Hippocampus. vol 20. issue 7. 2010-09-28. PMID:19623606.' |
the antidepressant effects of running and escitalopram are associated with levels of hippocampal npy and y1 receptor but not cell proliferation in a rat model of depression. |
2010-09-28 |
2023-08-12 |
rat |
| b' Astrid Bj\\xc3\\xb8rnebekk, Aleksander A Math\\xc3\\xa9, Stefan Bren\\xc3\\xa. The antidepressant effects of running and escitalopram are associated with levels of hippocampal NPY and Y1 receptor but not cell proliferation in a rat model of depression. Hippocampus. vol 20. issue 7. 2010-09-28. PMID:19623606.' |
one hypothesis of depression is that it is caused by reduced neuronal plasticity including hippocampal neurogenesis. |
2010-09-28 |
2023-08-12 |
rat |
| S Brummelte, L A M Gale. Chronic high corticosterone reduces neurogenesis in the dentate gyrus of adult male and female rats. Neuroscience. vol 168. issue 3. 2010-09-21. PMID:20406669. |
adult neurogenesis in the dentate gyrus of the hippocampus is altered with stress exposure and has been implicated in depression. |
2010-09-21 |
2023-08-12 |
human |
| Darrick T Bal. Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of acute and chronic antidepressant treatments. Experimental and clinical psychopharmacology. vol 18. issue 1. 2010-09-20. PMID:20158296. |
adult hippocampal neurogenesis has been implicated in the pathophysiology of depression and in the therapeutic effects of antidepressant drugs. |
2010-09-20 |
2023-08-12 |
mouse |
| Hsiao Hua Wu, Sabrina Wan. Strain differences in the chronic mild stress animal model of depression. Behavioural brain research. vol 213. issue 1. 2010-09-13. PMID:20438768. |
in the present study, we used a chronic mild stress (cms) animal model of depression to examine the responses of three strains of rats that have different hpa axis responsiveness; and whether the behavioral changes observed are correlated with changes in hippocampal cell proliferation and survival. |
2010-09-13 |
2023-08-12 |
rat |
| Susana Aznar, Anders B Klein, Martin A Santini, Gitte M Knudsen, Fritz Henn, Peter Gass, Barbara Vollmay. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20222154. |
aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced bdnf levels in hippocampus of rats bred for learned helplessness. |
2010-09-08 |
2023-08-12 |
rat |
| Susana Aznar, Anders B Klein, Martin A Santini, Gitte M Knudsen, Fritz Henn, Peter Gass, Barbara Vollmay. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20222154. |
both reduced hippocampal serotonin neurotransmission and brain-derived neurotrophic factor (bdnf) levels have been associated with increased depression vulnerability and are also regulated during aging. |
2010-09-08 |
2023-08-12 |
rat |
| Vincent Villette, Frédérique Poindessous-Jazat, Axelle Simon, Clément Léna, Elodie Roullot, Brice Bellessort, Jacques Epelbaum, Patrick Dutar, Aline Stépha. Decreased rhythmic GABAergic septal activity and memory-associated theta oscillations after hippocampal amyloid-beta pathology in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 33. 2010-09-03. PMID:20720106. |
such results indicate that hippocampal abeta treatment leads to a specific functional depression of inhibitory projection neurons of the medial septum, resulting in the functional impairment of the temporal network. |
2010-09-03 |
2023-08-12 |
rat |
| Erik B Bloss, Richard G Hunte. Hippocampal kainate receptors. Vitamins and hormones. vol 82. 2010-08-20. PMID:20472138. |
here, we review the anatomical and functional characteristics of hippocampal kars, their role in synaptic plasticity, their regulation by certain hormones, and briefly review what is known about their involvement in disease states such as epilepsy and depression. |
2010-08-20 |
2023-08-12 |
human |
| Li-hua Jiang, Ling-ling Wan. [Gene chips-aided analysis on the profiles of hippocampal whole-genome expression in depression rats following electroacupuncture treatment]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 2. 2010-08-17. PMID:20626138. |
[gene chips-aided analysis on the profiles of hippocampal whole-genome expression in depression rats following electroacupuncture treatment]. |
2010-08-17 |
2023-08-12 |
rat |
| Li-hua Jiang, Ling-ling Wan. [Gene chips-aided analysis on the profiles of hippocampal whole-genome expression in depression rats following electroacupuncture treatment]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 2. 2010-08-17. PMID:20626138. |
to observe the effect of electroacupuncture (ea) on the profiles of hippocampal whole-genome expression in depression rats so as to study its underlying mechanism in relieving depression. |
2010-08-17 |
2023-08-12 |
rat |
| Jayanthi Maniam, Margaret J Morri. Palatable cafeteria diet ameliorates anxiety and depression-like symptoms following an adverse early environment. Psychoneuroendocrinology. vol 35. issue 5. 2010-08-10. PMID:19939573. |
we assessed depression and anxiety-like behaviour with sucrose preference test (spt) and elevated plus maze (epm) respectively, and measured hypothalamic crh and hippocampal glucocorticoid receptor (gr) expression. |
2010-08-10 |
2023-08-12 |
rat |
| Ján Lehotský, Peter Racay, Martina Pavlíková, Zuzana Tatarková, Peter Urban, Mária Chomová, Mária Kovalská, Peter Kaplá. Cross-talk of intracellular calcium stores in the response to neuronal ischemia and ischemic tolerance. General physiology and biophysics. vol 28 Spec No Focus. 2010-08-10. PMID:20093720. |
ipc also incompletely suppresses lipo- and protein oxidation of hippocampal membranes and leads to partial recovery of the ischemic-induced depression of spca activity. |
2010-08-10 |
2023-08-12 |
Not clear |
| Eduardo Pineda, Don Shin, Raman Sankar, Andrey M Mazarat. Comorbidity between epilepsy and depression: experimental evidence for the involvement of serotonergic, glucocorticoid, and neuroinflammatory mechanisms. Epilepsia. vol 51 Suppl 3. 2010-08-03. PMID:20618414. |
pharmacologic studies have suggested that depressive impairments following se develop as a result of enhanced interleukin-1beta signaling in the hippocampus, which leads to depression via inducing perturbations in the hpa axis and subsequent deficit in the raphe-hippocampal serotonergic transmission. |
2010-08-03 |
2023-08-12 |
rat |
| Smita Thakker-Varia, Ying Y Jean, Payal Parikh, Caroline F Sizer, Jennifer Jernstedt Ayer, Ankit Parikh, Thomas M Hyde, Steven Buyske, Janet Alde. The neuropeptide VGF is reduced in human bipolar postmortem brain and contributes to some of the behavioral and molecular effects of lithium. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 28. 2010-07-30. PMID:20631166. |
recent studies demonstrate that the neuropeptide vgf (nonacronymic) is regulated in the hippocampus by antidepressant therapies and animal models of depression and that acute vgf treatment has antidepressant-like activity in animal paradigms. |
2010-07-30 |
2023-08-12 |
mouse |
| Gregers Wegener, Brian H Harvey, Birgit Bonefeld, Heidi K Müller, Vallo Volke, David H Overstreet, Betina Elfvin. Increased stress-evoked nitric oxide signalling in the Flinders sensitive line (FSL) rat: a genetic animal model of depression. The international journal of neuropsychopharmacology. vol 13. issue 4. 2010-07-14. PMID:19627650. |
stress engenders the precipitation and progression of affective disorders, while stress-related release of excitatory mediators is implicated in the degenerative pathology observed especially in the hippocampus of patients with severe depression. |
2010-07-14 |
2023-08-12 |
rat |
| Lei Chen, Haofei Wang, Zhuo Zhang, Zhen Li, Danjun He, Masahiro Sokabe, Ling Che. DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-) ) injected mice through preventing the dysfunction of alpha7 nicotinic receptor. Journal of neuroscience research. vol 88. issue 8. 2010-07-12. PMID:20127813. |
importantly, the treatment with dmxb (1 mg/kg) perfectly prevented abeta(25-35)-induced depression of alpha7nachr response, which was associated with improving the probability of presynaptic glutamate release and the induction of high-frequency stimulation (hfs)-dependent long-term potentiation (ltp) in hippocampal schaffer collaterale-ca1 synapse. |
2010-07-12 |
2023-08-12 |
mouse |
| Shiro Suda, Genichi Sugihara, Rie Suyama, Norio Mori, Nori Take. Donepezil and concurrent sertraline treatment is associated with increased hippocampal volume in a patient with depression. The Journal of clinical psychiatry. vol 71. issue 6. 2010-07-12. PMID:20573331. |
donepezil and concurrent sertraline treatment is associated with increased hippocampal volume in a patient with depression. |
2010-07-12 |
2023-08-12 |
Not clear |