| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dong Hoon Oh, Yong Chon Park, Seok Hyeon Ki. Increased glycogen synthase kinase-3β mRNA level in the hippocampus of patients with major depression: a study using the stanley neuropathology consortium integrative database. Psychiatry investigation. vol 7. issue 3. 2011-07-14. PMID:20927309. |
increased glycogen synthase kinase-3β mrna level in the hippocampus of patients with major depression: a study using the stanley neuropathology consortium integrative database. |
2011-07-14 |
2023-08-12 |
Not clear |
| Dong Hoon Oh, Yong Chon Park, Seok Hyeon Ki. Increased glycogen synthase kinase-3β mRNA level in the hippocampus of patients with major depression: a study using the stanley neuropathology consortium integrative database. Psychiatry investigation. vol 7. issue 3. 2011-07-14. PMID:20927309. |
a recent animal study reported increased gsk-3β messenger ribonucleic acid (mrna) level in the hippocampus of those with depression. |
2011-07-14 |
2023-08-12 |
Not clear |
| Chittaranjan Andrade, N Sanjay Kumar Ra. How antidepressant drugs act: A primer on neuroplasticity as the eventual mediator of antidepressant efficacy. Indian journal of psychiatry. vol 52. issue 4. 2011-07-14. PMID:21267376. |
pathological stress and depression are associated with changes such as loss of dendritic spines, shrinkage of the dendritic tree and loss of synapses in the hippocampus and prefrontal cortex. |
2011-07-14 |
2023-08-12 |
human |
| Harmen J Krugers, Paul J Lucassen, Henk Karst, Marian Joël. Chronic stress effects on hippocampal structure and synaptic function: relevance for depression and normalization by anti-glucocorticoid treatment. Frontiers in synaptic neuroscience. vol 2. 2011-07-14. PMID:21423510. |
chronic stress effects on hippocampal structure and synaptic function: relevance for depression and normalization by anti-glucocorticoid treatment. |
2011-07-14 |
2023-08-12 |
Not clear |
| Joseph Goveas, Chunming Xie, Zhilin Wu, B Douglas Ward, Wenjun Li, Malgorzata B Franczak, Jennifer L Jones, Piero G Antuono, Zheng Yang, Shi-Jiang L. Neural correlates of the interactive relationship between memory deficits and depressive symptoms in nondemented elderly: resting fMRI study. Behavioural brain research. vol 219. issue 2. 2011-07-13. PMID:21238490. |
voxelwise linear regression analysis was performed to correlate hippocampal network strength with the rey auditory verbal learning test delayed recall and the geriatric depression scale scores, after adjusting for age and group effects. |
2011-07-13 |
2023-08-12 |
human |
| Orla Watters, Mark Pickering, John J O'Conno. Preconditioning effects of tumor necrosis factor-α and glutamate on calcium dynamics in rat organotypic hippocampal cultures. Journal of neuroimmunology. vol 234. issue 1-2. 2011-07-11. PMID:21402417. |
both tnf-α and glutamate also resulted in the reduction of the proportion (p) of responsive cells within the ca region of the hippocampus (control; p=0.459, 0.451 ≤ x ≥ 0.467, n=14,968 cells, tnf-α; p=0.40, 0.392 ≤ x ≥ 0.407, n=15,218; glutamate; p=0.388, 0.303 ≤ x ≥ 0.396, n=13,919 cells), and in the depression of the frequency of spontaneous ca(2+) events (vs. control: tnf-α: p>0.00001, d=0.0454; glutamate: p>0.0001, d=0.0534). |
2011-07-11 |
2023-08-12 |
rat |
| Talley J Lambert, Daniel R Storm, Jane M Sulliva. MicroRNA132 modulates short-term synaptic plasticity but not basal release probability in hippocampal neurons. PloS one. vol 5. issue 12. 2011-07-05. PMID:21206919. |
here we show that overexpression of mir132 increases the paired-pulse ratio and decreases synaptic depression in cultured mouse hippocampal neurons without affecting the initial probability of neurotransmitter release, the calcium sensitivity of release, the amplitude of excitatory postsynaptic currents or the size of the readily releasable pool of synaptic vesicles. |
2011-07-05 |
2023-08-12 |
mouse |
| Heike Tost, Andreas Meyer-Lindenber. A new, blue gene highlights glutamate and hippocampus in depression. Neuron. vol 70. issue 2. 2011-07-01. PMID:21521605. |
a new, blue gene highlights glutamate and hippocampus in depression. |
2011-07-01 |
2023-08-12 |
Not clear |
| Heike Tost, Andreas Meyer-Lindenber. A new, blue gene highlights glutamate and hippocampus in depression. Neuron. vol 70. issue 2. 2011-07-01. PMID:21521605. |
(2011) reports a novel genome-wide supported risk variant for depression that affects hippocampal gene expression, anatomy, and biochemistry. |
2011-07-01 |
2023-08-12 |
Not clear |
| V Bhagya, B N Srikumar, T R Raju, B S Shankaranarayana Ra. Chronic escitalopram treatment restores spatial learning, monoamine levels, and hippocampal long-term potentiation in an animal model of depression. Psychopharmacology. vol 214. issue 2. 2011-06-28. PMID:21052984. |
chronic escitalopram treatment restores spatial learning, monoamine levels, and hippocampal long-term potentiation in an animal model of depression. |
2011-06-28 |
2023-08-12 |
Not clear |
| Benjamin A Samuels, René He. Neurogenesis and affective disorders. The European journal of neuroscience. vol 33. issue 6. 2011-06-24. PMID:21395859. |
the neurogenesis hypothesis of depression was originally formed upon the demonstration that stress impacts levels of adult neurogenesis in the hippocampus. |
2011-06-24 |
2023-08-12 |
Not clear |
| Charlotte A Oomen, Heleen Soeters, Nathalie Audureau, Lisa Vermunt, Felisa N van Hasselt, Erik M M Manders, Marian Joëls, Harm Krugers, Paul J Lucasse. Early maternal deprivation affects dentate gyrus structure and emotional learning in adult female rats. Psychopharmacology. vol 214. issue 1. 2011-06-20. PMID:20589492. |
patients suffering from depression show a reduced hippocampal volume, and in women, this occurs more often when depression is preceded by childhood trauma. |
2011-06-20 |
2023-08-12 |
rat |
| Diana M Mathis, Jennifer L Furman, Christopher M Norri. Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology. Journal of visualized experiments : JoVE. issue 49. 2011-06-15. PMID:21490565. |
changes in the induction of long-term potentiation and depression (ltp and ltd) of synaptic efficacy in hippocampal slices (or lack thereof) are frequently used to describe the neurologic phenotype of cognitively-impaired animals and/or to evaluate the mechanism of action of nootropic compounds. |
2011-06-15 |
2023-08-12 |
mouse |
| Yan Gu, Stephen Janoschka, Shaoyu G. Studying the integration of adult-born neurons. Journal of visualized experiments : JoVE. issue 49. 2011-06-15. PMID:21490569. |
previous reports have shown that adult hippocampal neurogenesis is associated with diverse brain disorders, including epilepsy, schizophrenia, depression and anxiety (1). |
2011-06-15 |
2023-08-12 |
Not clear |
| Andrea Saros. Neurocognition and psychogenetic vulnerability in depression. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 13. issue 1. 2011-06-14. PMID:21451189. |
relative to controls, patients with depression showed significant impairment on most neurocognitive tasks, but not in tasks measuring visuo-spatial function, which may suggest intact hippocampal function in depression. |
2011-06-14 |
2023-08-12 |
Not clear |
| Katharina Eikermann-Haerter, Izumi Yuzawa, Tao Qin, Yumei Wang, Kwangyeol Baek, Young Ro Kim, Ulrike Hoffmann, Ergin Dilekoz, Christian Waeber, Michel D Ferrari, Arn M J M van den Maagdenberg, Michael A Moskowitz, Cenk Ayat. Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 15. 2011-06-13. PMID:21490217. |
altogether, these data show that spreading depression propagates between cortex, basal ganglia, diencephalon, and hippocampus in genetically susceptible brains, which could explain the prolonged hemiplegia, coma, and seizure phenotype in this variant of migraine with aura. |
2011-06-13 |
2023-08-12 |
mouse |
| Brigitte A Apfel, Jessica Ross, Jennifer Hlavin, Dieter J Meyerhoff, Thomas J Metzler, Charles R Marmar, Michael W Weiner, Norbert Schuff, Thomas C Neyla. Hippocampal volume differences in Gulf War veterans with current versus lifetime posttraumatic stress disorder symptoms. Biological psychiatry. vol 69. issue 6. 2011-06-10. PMID:21094937. |
decreased hippocampal volume is described in posttraumatic stress disorder (ptsd) and depression. |
2011-06-10 |
2023-08-12 |
Not clear |
| G MacQueen, T Frod. The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research? Molecular psychiatry. vol 16. issue 3. 2011-06-03. PMID:20661246. |
the hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research? |
2011-06-03 |
2023-08-12 |
Not clear |
| G MacQueen, T Frod. The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research? Molecular psychiatry. vol 16. issue 3. 2011-06-03. PMID:20661246. |
the pathways through which stress may be linked to mdd, the emergence of chronicity or treatment resistance in mdd and the association between mdd and memory problems may be at least partially understood by dissecting the association with depression and changes in the hippocampus. |
2011-06-03 |
2023-08-12 |
Not clear |
| Joanna L Workman, Randy J Nelso. Potential animal models of seasonal affective disorder. Neuroscience and biobehavioral reviews. vol 35. issue 3. 2011-06-01. PMID:20800614. |
current research in depression and animal models of depression suggests that hippocampal plasticity may underlie the symptoms of depression and depressive-like behaviors, respectively. |
2011-06-01 |
2023-08-12 |
human |