| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Mitschelen, H Yan, J A Farley, J P Warrington, S Han, C B Hereñú, A Csiszar, Z Ungvari, L C Bailey-Downs, C E Bass, W E Sonnta. Long-term deficiency of circulating and hippocampal insulin-like growth factor I induces depressive behavior in adult mice: a potential model of geriatric depression. Neuroscience. vol 185. 2011-09-19. PMID:21524689. |
long-term deficiency of circulating and hippocampal insulin-like growth factor i induces depressive behavior in adult mice: a potential model of geriatric depression. |
2011-09-19 |
2023-08-12 |
mouse |
| Jennifer L Sanderson, Mark L Dell'Acqu. AKAP signaling complexes in regulation of excitatory synaptic plasticity. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 17. issue 3. 2011-09-12. PMID:21498812. |
long-term potentiation (ltp) and depression (ltd) in the hippocampal region of the brain are two forms of synaptic plasticity that increase or decrease, respectively, the strength of synaptic transmission by postsynaptic ampa-type glutamate receptors. |
2011-09-12 |
2023-08-12 |
human |
| Girstautė Dagytė, Johan A Den Boer, Andrea Trentan. The cholinergic system and depression. Behavioural brain research. vol 221. issue 2. 2011-09-09. PMID:20170685. |
changes in hippocampal neurogenesis, often associated with chronic stress in animal models, may be in part mediated by cholinergic dysfunction, which in turn could underlie the cognitive disturbances observed in depression. |
2011-09-09 |
2023-08-12 |
Not clear |
| Maki Kasahara, Lucianne Groenink, Berend Olivier, Zoltan Sarnya. Corticotropin-releasing factor (CRF) over-expression down-regulates hippocampal dopamine receptor protein expression and CREB activation in mice. Neuro endocrinology letters. vol 32. issue 2. 2011-09-08. PMID:21552199. |
stress results in hyperactivity of the hypothalamic-pituitary-adrenal (hpa) axis, characterized by increased central crf activity, elevated circulating glucocorticoid levels, impaired glucocorticoid-mediated negative feedback and abnormal hippocampal functions, possibly contributing to the development of behavioral pathologies, such as depression. |
2011-09-08 |
2023-08-12 |
mouse |
| Y A Khadrawy, K A I El-Shamy, S I Mohame. Nicotine restores monoamine neurotransmitter changes in the cortex and hippocampus of reserpinized rats as a model of depression. European review for medical and pharmacological sciences. vol 15. issue 8. 2011-09-06. PMID:21845795. |
nicotine restores monoamine neurotransmitter changes in the cortex and hippocampus of reserpinized rats as a model of depression. |
2011-09-06 |
2023-08-12 |
rat |
| Y A Khadrawy, K A I El-Shamy, S I Mohame. Nicotine restores monoamine neurotransmitter changes in the cortex and hippocampus of reserpinized rats as a model of depression. European review for medical and pharmacological sciences. vol 15. issue 8. 2011-09-06. PMID:21845795. |
the aim of the present study is to elucidate the neurochemical effect of nicotine on monoamine levels in the cerebral cortex and hippocampus of reserpinized rats as a model of depression. |
2011-09-06 |
2023-08-12 |
rat |
| Nobuko Yamada, Goro Katsuura, Yukari Ochi, Ken Ebihara, Toru Kusakabe, Kiminori Hosoda, Kazuwa Naka. Impaired CNS leptin action is implicated in depression associated with obesity. Endocrinology. vol 152. issue 7. 2011-09-02. PMID:21521746. |
thus, depression associated with obesity is due, at least in part, to impaired leptin activity in the hippocampus. |
2011-09-02 |
2023-08-12 |
mouse |
| Sâmia Regiane L Joca, Cláudia Maria Padovan, Francisco Silveira Guimarãe. [Stress, depression and the hippocampus]. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). vol 25 Suppl 2. 2011-08-15. PMID:14978587. |
[stress, depression and the hippocampus]. |
2011-08-15 |
2023-08-12 |
rat |
| Sâmia Regiane L Joca, Cláudia Maria Padovan, Francisco Silveira Guimarãe. [Stress, depression and the hippocampus]. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). vol 25 Suppl 2. 2011-08-15. PMID:14978587. |
antidepressive drugs attenuate these effects, probably by increasing the expression of neurotrophic factors; 2. facilitation of serotonergic neurotransmission in the hippocampus attenuates behavioral consequences of stress and produce antidepressive-like effects in several animal models; 3. antagonism of glutamate, the main excitatory neurotransmitter of the hippocampus, also induce antidepressive-like effects; 4. increased hippocampal activity has been described in genetically selected rats that are more sensitive to depression models. |
2011-08-15 |
2023-08-12 |
rat |
| Mia Thompson Ray, Cynthia Shannon Weickert, Eugene Wyatt, Maree J Webste. Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders. Journal of psychiatry & neuroscience : JPN. vol 36. issue 3. 2011-08-15. PMID:21223646. |
to determine whether this reduction extends to other brain regions, we measured the expression levels of bdnf, trkb-tk+ and gad67 mrna in regions of the hippocampus, including the dentate gyrus (dg), cornu ammonis subfields (ca1-4), subiculum and entorhinal cortex (ec) of individuals with schizophrenia, bipolar disorder, major depression and unaffected controls. |
2011-08-15 |
2023-08-12 |
Not clear |
| Barbara Nowak, Monika Zadrożna, Grażyna Ossowska, Magdalena Sowa-Kućma, Piotr Gruca, Mariusz Papp, Małgorzata Dybała, Andrzej Pilc, Gabriel Nowa. Alterations in hippocampal calcium-binding neurons induced by stress models of depression: a preliminary assessment. Pharmacological reports : PR. vol 62. issue 6. 2011-08-10. PMID:21273679. |
alterations in hippocampal calcium-binding neurons induced by stress models of depression: a preliminary assessment. |
2011-08-10 |
2023-08-12 |
rat |
| Jeffrey Burgdorf, Xiao-lei Zhang, Craig Weiss, Elizabeth Matthews, John F Disterhoft, Patric K Stanton, Joseph R Moska. The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging rats. Neurobiology of aging. vol 32. issue 4. 2011-08-08. PMID:19446371. |
examination of the induction of long-term potentiation (ltp) and depression (ltd) at schaffer collateral-ca1 synapses in hippocampal slices showed that aged rats showed marked, selective impairment in the magnitude of ltp evoked by a sub-maximal tetanus, and that glyx-13 significantly enhanced the magnitude of ltp in slices from both young adult and aged rats without affecting ltd. |
2011-08-08 |
2023-08-12 |
rat |
| Francesco Matrisciano, Carla L Busceti, Domenico Bucci, Rosamaria Orlando, Alessandra Caruso, Gemma Molinaro, Irene Cappuccio, Barbara Riozzi, Roberto Gradini, Marta Motolese, Filippo Caraci, Agata Copani, Sergio Scaccianoce, Daniela Melchiorri, Valeria Bruno, Giuseppe Battaglia, Ferdinando Nicolett. Induction of the Wnt antagonist Dickkopf-1 is involved in stress-induced hippocampal damage. PloS one. vol 6. issue 1. 2011-08-02. PMID:21304589. |
drugs that rescue the canonical wnt pathway may attenuate hippocampal damage in major depression and other stress-related disorders. |
2011-08-02 |
2023-08-12 |
mouse |
| Miyoung Yang, Joong-Sun Kim, Juhwan Kim, Sung-Ho Kim, Jong-Choon Kim, Jinwook Kim, Hongbing Wang, Taekyun Shin, Changjong Moo. Neurotoxicity of methotrexate to hippocampal cells in vivo and in vitro. Biochemical pharmacology. vol 82. issue 1. 2011-08-01. PMID:21459079. |
results of this study suggest that the neurotoxic effect of mtx inhibits the proliferation of hippocampal progenitor cells and can cause hippocampal dysfunction, such as depression and cognitive impairment. |
2011-08-01 |
2023-08-12 |
mouse |
| Emmanuelle Corruble, Bruno Falissard, Philip Gorwoo. DSM bereavement exclusion for major depression and objective cognitive impairment. Journal of affective disorders. vol 130. issue 1-2. 2011-07-29. PMID:21059473. |
this study aimed at assessing objective cognitive impairment, reflecting hippocampal function, in patients excluded from the diagnosis of major depression because of the bereavement exclusion. |
2011-07-29 |
2023-08-12 |
Not clear |
| O Bozdagi, X B Wang, G P Martinelli, G Prell, V L Friedrich, G W Huntley, G R Holstei. Imidazoleacetic acid-ribotide induces depression of synaptic responses in hippocampus through activation of imidazoline receptors. Journal of neurophysiology. vol 105. issue 3. 2011-07-22. PMID:21228308. |
imidazoleacetic acid-ribotide induces depression of synaptic responses in hippocampus through activation of imidazoline receptors. |
2011-07-22 |
2023-08-12 |
rat |
| Pawel Lisowski, Grzegorz R Juszczak, Joanna Goscik, Marek Wieczorek, Lech Zwierzchowski, Artur H Swiergie. Effect of chronic mild stress on hippocampal transcriptome in mice selected for high and low stress-induced analgesia and displaying different emotional behaviors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21. issue 1. 2011-07-20. PMID:20961740. |
stress-induced hippocampal plasticity has been implicated in depression. |
2011-07-20 |
2023-08-12 |
mouse |
| K Printha, S R Hulathduwa, K Samarasinghe, Y H Suh, K R D De Silv. Apoptosis in subicular neurons: A comparison between suicide and Addison's disease. Indian journal of psychiatry. vol 51. issue 4. 2011-07-14. PMID:20048453. |
stress and depression shows possible links to neuronal death in hippocampus. |
2011-07-14 |
2023-08-12 |
Not clear |
| Waldo Cerpa, Ginny G Farías, Juan A Godoy, Marco Fuenzalida, Christian Bonansco, Nibaldo C Inestros. Wnt-5a occludes Abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons. Molecular neurodegeneration. vol 5. 2011-07-14. PMID:20205789. |
wnt-5a occludes abeta oligomer-induced depression of glutamatergic transmission in hippocampal neurons. |
2011-07-14 |
2023-08-12 |
Not clear |
| Friederike Klempin, Harish Babu, Davide De Pietri Tonelli, Edson Alarcon, Klaus Fabel, Gerd Kemperman. Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis. Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20721314. |
serotonin (5-ht) appears to play a major role in controlling adult hippocampal neurogenesis and thereby it is relevant for theories linking failing adult neurogenesis to the pathogenesis of major depression and the mechanisms of action of antidepressants. |
2011-07-14 |
2023-08-12 |
Not clear |