| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Bourdeaux, P Pannetier, D Desor, P R Lehr, C Younos, B Capolagh. [Effect of fluoxetine treatment on serotonin and MHPG in 32 patients with major depressive disorder]. L'Encephale. vol 25. issue 1. 1999-06-17. PMID:10205732. |
considering the concept that depressive disorders were not only resulting from activity of one neurotransmitter, possible interactions between the noradrenergic system and a selective serotonin uptake inhibitor, fluoxetine, were investigated in order to test the hypothesis of noradrenergic or serotonergic involvement in depression. |
1999-06-17 |
2023-08-12 |
human |
| K J Holm, A Markha. Mirtazapine: a review of its use in major depression. Drugs. vol 57. issue 4. 1999-06-15. PMID:10235695. |
mirtazapine is a noradrenergic and specific serotonergic antidepressant (nassa) which has predominantly been evaluated in the treatment of major depression. |
1999-06-15 |
2023-08-12 |
Not clear |
| T J Connor, C Song, B E Leonard, H Anisman, Z Meral. Stressor-induced alterations in serotonergic activity in an animal model of depression. Neuroreport. vol 10. issue 3. 1999-06-10. PMID:10208583. |
stressor-induced alterations in serotonergic activity in an animal model of depression. |
1999-06-10 |
2023-08-12 |
rat |
| T J Connor, C Song, B E Leonard, H Anisman, Z Meral. Stressor-induced alterations in serotonergic activity in an animal model of depression. Neuroreport. vol 10. issue 3. 1999-06-10. PMID:10208583. |
on accumbal serotonergic neurotransmission in the olfactory bulbectomized (ob) rat model of depression. |
1999-06-10 |
2023-08-12 |
rat |
| J Neuger, A El Khoury, B F Kjellman, B Wahlund, A Aberg-Wistedt, R Stain-Malmgre. Platelet serotonin functions in untreated major depression. Psychiatry research. vol 85. issue 2. 1999-06-07. PMID:10220009. |
the results in the present study indicate that there may be a gender difference in serotonergic dysfunction in depression. |
1999-06-07 |
2023-08-12 |
human |
| E Smeraldi, F Benedetti, B Barbini, E Campori, C Colomb. Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression. A placebo-controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 20. issue 4. 1999-06-03. PMID:10088139. |
this results suggest a major role for serotonergic transmission in the mechanism of action of tsd, and makes tsd treatment more effective in the treatment of bipolar depression. |
1999-06-03 |
2023-08-12 |
Not clear |
| L W Maines, B J Keck, J E Smith, J M Lakosk. Corticosterone regulation of serotonin transporter and 5-HT1A receptor expression in the aging brain. Synapse (New York, N.Y.). vol 32. issue 1. 1999-06-01. PMID:10188639. |
as the serotonergic (5-hydroxytryptamine; 5-ht) system plays a major role in the etiology of depression, a loss of endocrine and neurotransmitter system interactions, including corticosterone regulation of 5-ht transporter (5-htt) and 5-ht receptor expression, may underlie age-related deficits in the regulation of the hypothalamic-pituitary-adrenal (hpa) axis and correlate with an increased incidence of depression with advancing age. |
1999-06-01 |
2023-08-12 |
rat |
| L W Maines, B J Keck, J E Smith, J M Lakosk. Corticosterone regulation of serotonin transporter and 5-HT1A receptor expression in the aging brain. Synapse (New York, N.Y.). vol 32. issue 1. 1999-06-01. PMID:10188639. |
overall, an age-associated deficit in the regulation of the hippocampal serotonergic system by varied corticosterone treatment was revealed in the present study, which may underlie the increased incidence of depression and hypercortisolemia found with advancing age. |
1999-06-01 |
2023-08-12 |
rat |
| H Joffe, L S Cohe. Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge? Biological psychiatry. vol 44. issue 9. 1999-05-04. PMID:9807636. |
the ability of estrogen to modulate serotonergic function, in particular, raises the possibility that sex steroids may play a role in the mechanisms associated with depression and its treatment. |
1999-05-04 |
2023-08-12 |
Not clear |
| M Vijayakumar, B L Met. Alterations in the levels of monoamines in discrete brain regions of clomipramine-induced animal model of endogenous depression. Neurochemical research. vol 24. issue 3. 1999-04-16. PMID:10215507. |
it has been hypothesized that the dysfunction of the serotonergic and catecholaminergic neurotransmission is involved in the pathogenesis of depression. |
1999-04-16 |
2023-08-12 |
human |
| M Vijayakumar, B L Met. Alterations in the levels of monoamines in discrete brain regions of clomipramine-induced animal model of endogenous depression. Neurochemical research. vol 24. issue 3. 1999-04-16. PMID:10215507. |
our results demonstrate the dysfunction of serotonergic and noradrenergic neurotransmission, with lesser involvement of dopaminergic neurotransmission in the clomipramine induced experimental model of depression. |
1999-04-16 |
2023-08-12 |
human |
| b' M Maes, A H Lin, R Verkerk, L Delmeire, A Van Gastel, M Van der Planken, S Scharp\\xc3\\xa. Serotonergic and noradrenergic markers of post-traumatic stress disorder with and without major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 20. issue 2. 1999-03-29. PMID:9885798.' |
serotonergic and noradrenergic markers of post-traumatic stress disorder with and without major depression. |
1999-03-29 |
2023-08-12 |
human |
| K A Stolp-Smith, M C Wainber. Antidepressant exacerbation of spasticity. Archives of physical medicine and rehabilitation. vol 80. issue 3. 1999-03-29. PMID:10084445. |
understanding the relationship between serotonergic systems and spasticity can be important in treating depression in patients with spasticity. |
1999-03-29 |
2023-08-12 |
Not clear |
| M J Moore, P B Moore, P J Sha. Mood disturbances in motor neurone disease. Journal of the neurological sciences. vol 160 Suppl 1. 1999-03-18. PMID:9851650. |
depression is believed to result from underactivity of the serotonergic neurotransmitter system. |
1999-03-18 |
2023-08-12 |
Not clear |
| F K Goodwi. Anticonvulsant therapy and suicide risk in affective disorders. The Journal of clinical psychiatry. vol 60 Suppl 2. 1999-03-18. PMID:10073394. |
established risk factors for completed suicide in affective disorders include acute depression (with turmoil, hopelessness, global insomnia, anhedonia, anxiety and/or panic), mixed episodes, rapid cycling, substance abuse, aggression and/or impulsivity, low serotonergic activity, and hypothalamic-pituitary-adrenal axis activation. |
1999-03-18 |
2023-08-12 |
Not clear |
| H Ito, C Halldin, L Fard. Localization of 5-HT1A receptors in the living human brain using [carbonyl-11C]WAY-100635: PET with anatomic standardization technique. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 40. issue 1. 1999-02-25. PMID:9935065. |
serotonergic 5-hydroxytryptamine-1a (5-ht1a) receptors are of interest in the pathophysiology of several neuropsychiatric disorders such as anxiety, depression and schizophrenia. |
1999-02-25 |
2023-08-12 |
human |
| H M van Praa. Anxiety and increased aggression as pacemakers of depression. Acta psychiatrica Scandinavica. Supplementum. vol 393. 1999-01-14. PMID:9777052. |
the author submits that the serotonergic impairment in certain types of depression is a trait phenomenon, i.e. |
1999-01-14 |
2023-08-12 |
Not clear |
| H M van Praa. Anxiety and increased aggression as pacemakers of depression. Acta psychiatrica Scandinavica. Supplementum. vol 393. 1999-01-14. PMID:9777052. |
the exact nature of the serotonergic impairment in 5-ht-related depression has yet to be elucidated. |
1999-01-14 |
2023-08-12 |
Not clear |
| J K Staley, R T Malison, R B Inni. Imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression. Biological psychiatry. vol 44. issue 7. 1999-01-06. PMID:9787877. |
imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression. |
1999-01-06 |
2023-08-12 |
human |
| J K Staley, R T Malison, R B Inni. Imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression. Biological psychiatry. vol 44. issue 7. 1999-01-06. PMID:9787877. |
for nearly three decades, evidence supporting a role for aberrant serotonergic function in the pathogenesis of depression has accumulated; however, only recently have methodologies and radiotracers suitable for in vivo clinical assessment of depression become available. |
1999-01-06 |
2023-08-12 |
human |