| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Akira Sakurai, Naïm R Darghouth, Robert J Butera, Paul S Kat. Serotonergic enhancement of a 4-AP-sensitive current mediates the synaptic depression phase of spike timing-dependent neuromodulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 7. 2006-04-24. PMID:16481434. |
serotonergic enhancement of a 4-ap-sensitive current mediates the synaptic depression phase of spike timing-dependent neuromodulation. |
2006-04-24 |
2023-08-12 |
Not clear |
| Akira Sakurai, Naïm R Darghouth, Robert J Butera, Paul S Kat. Serotonergic enhancement of a 4-AP-sensitive current mediates the synaptic depression phase of spike timing-dependent neuromodulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 7. 2006-04-24. PMID:16481434. |
the serotonergic dorsal swim interneurons (dsis) dynamically modulated the synaptic output of ventral swim interneuron b (vsi); immediately after dsi stimulation, there was a potentiation of vsi synaptic strength followed by a longer-lasting synaptic depression. |
2006-04-24 |
2023-08-12 |
Not clear |
| Kellie J White, Crystal C Walline, Eric L Barke. Serotonin transporters: implications for antidepressant drug development. The AAPS journal. vol 7. issue 2. 2006-04-06. PMID:16353921. |
the monoamine theory of depression suggests that disruptions in the serotonergic and noradrenergic systems result in depressive symptoms. |
2006-04-06 |
2023-08-12 |
Not clear |
| Victor B Fenik, Richard O Davies, Leszek Kubi. Noradrenergic, serotonergic and GABAergic antagonists injected together into the XII nucleus abolish the REM sleep-like depression of hypoglossal motoneuronal activity. Journal of sleep research. vol 14. issue 4. 2006-03-30. PMID:16364143. |
noradrenergic, serotonergic and gabaergic antagonists injected together into the xii nucleus abolish the rem sleep-like depression of hypoglossal motoneuronal activity. |
2006-03-30 |
2023-08-12 |
rat |
| Manoela Fonseca, Jair C Soares, John P Hatch, Aida P Santin, Flavio Kapczinsk. An open trial of adjunctive escitalopram in bipolar depression. The Journal of clinical psychiatry. vol 67. issue 1. 2006-03-28. PMID:16426092. |
this study was designed to evaluate the efficacy and safety of a highly potent and selective serotonergic antidepressant, escitalopram, in the treatment of bipolar depression. |
2006-03-28 |
2023-08-12 |
Not clear |
| Viktor Roman, Irene Walstra, Paul G M Luiten, Peter Meerl. Too little sleep gradually desensitizes the serotonin 1A receptor system. Sleep. vol 28. issue 12. 2006-03-21. PMID:16408408. |
one of the proposed neurobiological mechanisms underlying depression is a disturbance in the brain's serotonergic neurotransmission, particularly a desensitization of the serotonin (5-ht)1a receptor system. |
2006-03-21 |
2023-08-12 |
Not clear |
| B E Leonar. The HPA and immune axes in stress: the involvement of the serotonergic system. European psychiatry : the journal of the Association of European Psychiatrists. vol 20 Suppl 3. 2006-03-21. PMID:16459240. |
while crf would appear to play a pivotal role, evidence is provided that simultaneous changes in the serotonergic and noradrenergic systems, combined with the activation of peripheral and central macrophages that increase the pro-inflammatory cytokine concentrations in the brain and blood, also play a critical role in predisposing to anxiety and depression. |
2006-03-21 |
2023-08-12 |
Not clear |
| Catalina Lopez de Lara, Alexandre Dumais, Guy Rouleau, Alain Lesage, Mimi Dumont, Nadia Chawky, Martin Alda, Chawki Benkelfat, Gustavo Tureck. STin2 variant and family history of suicide as significant predictors of suicide completion in major depression. Biological psychiatry. vol 59. issue 2. 2006-03-09. PMID:16125146. |
serotonergic alterations have been observed in suicide and depression and impulsive-aggressive behaviors. |
2006-03-09 |
2023-08-12 |
Not clear |
| Nobuaki Egashira, Katsunori Iwasaki, Akihiko Takashima, Takuya Watanabe, Hideyuki Kawabe, Tomomi Matsuda, Kenichi Mishima, Shozo Chidori, Ryoji Nishimura, Michihiro Fujiwar. Altered depression-related behavior and neurochemical changes in serotonergic neurons in mutant R406W human tau transgenic mice. Brain research. vol 1059. issue 1. 2006-02-24. PMID:16182262. |
these results suggest that r406w tg mice exhibit changes in depression-related behavior involving serotonergic neurons and provide an animal model for investigating ad with depression. |
2006-02-24 |
2023-08-12 |
mouse |
| Leith C R Meyer, Andrea Fuller, Duncan Mitchel. Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 290. issue 2. 2006-02-23. PMID:16166206. |
neurophysiological studies have shown that serotonergic ligands that bind to 5-ht1a, 5-ht7, and 5-ht4 serotonin receptors in brain stem have beneficial effects on respiratory neurons during opioid-induced respiratory depression. |
2006-02-23 |
2023-08-12 |
Not clear |
| Leith C R Meyer, Andrea Fuller, Duncan Mitchel. Zacopride and 8-OH-DPAT reverse opioid-induced respiratory depression and hypoxia but not catatonic immobilization in goats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 290. issue 2. 2006-02-23. PMID:16166206. |
we conclude that serotonergic drugs that act on 5-ht1a, 5-ht7, and 5-ht4 receptors reverse opioid-induced respiratory depression and hypoxia without reversing catatonic immobilization. |
2006-02-23 |
2023-08-12 |
Not clear |
| S Mata, M Urbina, E Manzano, T Ortiz, L Lim. Noradrenaline transporter and its turnover rate are decreased in blood lymphocytes of patients with major depression. Journal of neuroimmunology. vol 170. issue 1-2. 2006-02-14. PMID:16242784. |
noradrenergic and serotonergic turnover is decreased in blood peripheral lymphocytes of major depression patients; the reduction in noradrenaline transporter could be related to changes in intracellular levels, and these modifications could result in functional changes of the immune system. |
2006-02-14 |
2023-08-12 |
Not clear |
| Jan Jaracz, Janusz Rybakowsk. [Depression and pain: novel clinical, neurobiological and psychopharmacological data]. Psychiatria polska. vol 39. issue 5. 2006-01-12. PMID:16358593. |
in the pathogenesis of both depression and pain symptoms, an important role has been attributed to disturbances of serotonergic and noradrenergic neurotransmission as well as to neuropeptides such as opioids and substance p. in mood regulation as well as in the perception and emotional dimension of pain stimuli, such brain structures as the amygdala, anterior cingulate cortex and prefrontal cortex are of main significance. |
2006-01-12 |
2023-08-12 |
Not clear |
| A Bickel, J Kornhuber, C Maihöfner, A Ropoh. Exacerbation of migraine attacks during treatment with the selective serotonin reuptake inhibitor sertraline. A case report. Pharmacopsychiatry. vol 38. issue 6. 2006-01-05. PMID:16342007. |
abnormal signal transmission in central serotonergic pathways is supposed to play an important role in the pathogenesis of migraine and major depression. |
2006-01-05 |
2023-08-12 |
Not clear |
| C Dalla, K Antoniou, G Drossopoulou, M Xagoraris, N Kokras, A Sfikakis, Z Papadopoulou-Daifot. Chronic mild stress impact: are females more vulnerable? Neuroscience. vol 135. issue 3. 2005-12-22. PMID:16125862. |
sex differences regarding the association of behavioral parameters with serotonergic and hypothalamic-pituitary-adrenal axis activities were investigated in the chronic mild stress model of depression. |
2005-12-22 |
2023-08-12 |
rat |
| Nitesh Painuly, Pratap Sharan, Surendra K Matto. Relationship of anger and anger attacks with depression: a brief review. European archives of psychiatry and clinical neuroscience. vol 255. issue 4. 2005-11-30. PMID:16133740. |
serotonergic dysfunction may characterize this distinct subtype of depression - depression with anger attacks. |
2005-11-30 |
2023-08-12 |
Not clear |
| A Broock. [Physical training in the treatment of psychological disorders]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. vol 48. issue 8. 2005-11-03. PMID:16086203. |
for instance, there is experimental evidence that regular exercise induces a downregulation of certain central serotonergic receptors, which play an important role in the pathogenesis of anxiety and depression. |
2005-11-03 |
2023-08-12 |
human |
| Shu Hasegawa, Arata Watanabe, Khanh Q Nguyen, Guy Debonnel, Mirko Diksi. Chronic administration of citalopram in olfactory bulbectomy rats restores brain 5-HT synthesis rates: an autoradiographic study. Psychopharmacology. vol 179. issue 4. 2005-09-15. PMID:15619103. |
the olfactory bulbectomized (obx) rat model is widely accepted as an animal model of depression with a proposed serotonergic imbalance in the brain. |
2005-09-15 |
2023-08-12 |
rat |
| Yaprak Engin-Ustün, Yusuf Ustün, Hakan Gürdal, Mete Güngö. Serotonergic activity and the Beck Depression Inventory in the premenstrual syndrome. The Journal of reproductive medicine. vol 50. issue 5. 2005-09-13. PMID:15971481. |
serotonergic activity and the beck depression inventory in the premenstrual syndrome. |
2005-09-13 |
2023-08-12 |
Not clear |
| A Syed, M Chatfield, F Matthews, P Harrison, C Brayne, M M Esir. Depression in the elderly: pathological study of raphe and locus ceruleus. Neuropathology and applied neurobiology. vol 31. issue 4. 2005-09-06. PMID:16008824. |
we found no relationship between depression and (1) mean counts of serotonergic or total rn neuronal profiles (2) noradrenergic or total lc neuronal profiles (3) counts of neurofibrillary tangles in these nuclei, or (4) size of neurones in the rn. |
2005-09-06 |
2023-08-12 |
human |