| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xianjie Wan, Jiale Xie, Mingyi Yang, Hui Yu, Weikun Hou, Ke Xu, Jiachen Wang, Peng X. Does Having Rheumatoid Arthritis Increase the Dose of Depression Medications? A Mendelian Randomization Study. Journal of clinical medicine. vol 12. issue 4. 2023-02-25. PMID:36835939. |
therefore, in this study, we used two-sample mendelian randomization (mr) to explore whether ra increases the dose of depression medications and gain a more comprehensive understanding of the relationship between ra and depression. |
2023-02-25 |
2023-08-14 |
Not clear |
| Lingsi Zeng, Honggang Lv, Xubo Wang, Ranran Xue, Cong Zhou, Xia Liu, Hao Y. Causal effects of fatty acids on depression: Mendelian randomization study. Frontiers in nutrition. vol 9. 2022-12-23. PMID:36562041. |
we aimed to investigate the potential causal relationship between fa [saturated fatty acids (sfa), mono-unsaturated fatty acids (mufa), and polyunsaturated fatty acids (pufa)] and the risk of depression using mendelian randomization (mr) analysis. |
2022-12-23 |
2023-08-14 |
Not clear |
| Harald Murck, Lisa Lehr, Daniela Jezov. A viewpoint on aldosterone and BMI related brain morphology in relation to treatment outcome in patients with major depression. Journal of neuroendocrinology. 2022-12-21. PMID:36539978. |
this review focuses on the importance of the adrenocortical stress hormone aldosterone, which is released by adrenocorticotropic hormone and angiotensin, and the mineralocorticoid receptor (mr) in depression. |
2022-12-21 |
2023-08-14 |
human |
| Christian Adolf, Harald Murck, Anna-Lina Sarkis, Holger Schneider, Daniel A Heinrich, Tracy Ann Williams, Martin Reincke, Heike Künze. Differential central regulatory mineralocorticoidreceptor systems for anxiety and depression - Could KCNJ5 be an interesting target for further investigations in major depression? Journal of psychiatric research. vol 156. 2022-10-15. PMID:36242946. |
the mineralocorticoid receptor (mr) is suggested to play a role in the pathophysiology of depression and anxiety. |
2022-10-15 |
2023-08-14 |
Not clear |
| Christian Adolf, Harald Murck, Anna-Lina Sarkis, Holger Schneider, Daniel A Heinrich, Tracy Ann Williams, Martin Reincke, Heike Künze. Differential central regulatory mineralocorticoidreceptor systems for anxiety and depression - Could KCNJ5 be an interesting target for further investigations in major depression? Journal of psychiatric research. vol 156. 2022-10-15. PMID:36242946. |
main support comes from studies in patients with primary aldosteronism (pa) which suggested different central pathways for depression and anxiety mediated via the mr and gender differences. |
2022-10-15 |
2023-08-14 |
Not clear |
| Christian Adolf, Harald Murck, Anna-Lina Sarkis, Holger Schneider, Daniel A Heinrich, Tracy Ann Williams, Martin Reincke, Heike Künze. Differential central regulatory mineralocorticoidreceptor systems for anxiety and depression - Could KCNJ5 be an interesting target for further investigations in major depression? Journal of psychiatric research. vol 156. 2022-10-15. PMID:36242946. |
we investigated 118 patients with pa over 3 years using self-rating questionnaires for anxiety (gad-7) and depression (phqd) at baseline and once a year under specific treatment with adrenalectomy (adx; n = 48) or a mr antagonist (mra; n = 70). |
2022-10-15 |
2023-08-14 |
Not clear |
| Christian Adolf, Harald Murck, Anna-Lina Sarkis, Holger Schneider, Daniel A Heinrich, Tracy Ann Williams, Martin Reincke, Heike Künze. Differential central regulatory mineralocorticoidreceptor systems for anxiety and depression - Could KCNJ5 be an interesting target for further investigations in major depression? Journal of psychiatric research. vol 156. 2022-10-15. PMID:36242946. |
these data support a differentiated regulation of depression and anxiety by the mr. |
2022-10-15 |
2023-08-14 |
Not clear |
| Evangelos Handakas, Yiwen Xu, Alexa Blair Segal, Maria Carmen Huerta, Kirsty Bowman, Laura D Howe, Franco Sassi, Oliver Robinso. Molecular mediators of the association between child obesity and mental health. Frontiers in genetics. vol 13. 2022-09-19. PMID:36118877. |
two-sample mendelian randomization (mr) analyses were additionally applied to test causal associations of metabolites with depression in independent adult samples. |
2022-09-19 |
2023-08-14 |
Not clear |
| Evangelos Handakas, Yiwen Xu, Alexa Blair Segal, Maria Carmen Huerta, Kirsty Bowman, Laura D Howe, Franco Sassi, Oliver Robinso. Molecular mediators of the association between child obesity and mental health. Frontiers in genetics. vol 13. 2022-09-19. PMID:36118877. |
in mr analysis, one unit increase in tyrosine was associated with 0.13 higher log odds of depression ( |
2022-09-19 |
2023-08-14 |
Not clear |
| Bastian Bruns, Ricarda Daub, Thomas Schmitz, Maria Hamze-Sinno, Sebastian Spaich, Matthias Dewenter, Chrysovalandis Schwale, Peter Gass, Miriam Vogt, Hugo Katus, Wolfgang Herzog, Hans-Christoph Friederich, Norbert Frey, Jobst-Hendrik Schultz, Johannes Back. Forebrain corticosteroid receptors promote post-myocardial infarction depression and mortality. Basic research in cardiology. vol 117. issue 1. 2022-09-06. PMID:36068417. |
impaired central mineralocorticoid (mr) and glucocorticoid receptor (gr) equilibrium has been suggested as a key mechanism in the pathogenesis of human depression. |
2022-09-06 |
2023-08-14 |
mouse |
| D Galan, B I Perry, V Warrier, C C Davidson, O Stupart, D Easton, G M Khandaker, G K Murra. Applying Mendelian randomization to appraise causality in relationships between smoking, depression and inflammation. Scientific reports. vol 12. issue 1. 2022-09-03. PMID:36057695. |
we performed inverse variance weighted mendelian randomization (mr) analyses using recently published summary-level gwas data for lifetime smoking index, crp levels, and depression. |
2022-09-03 |
2023-08-14 |
Not clear |
| E Wu, Jun-Tao Ni, Tian Xie, Lin Ta. Noncausal effects of genetic predicted depression and colorectal cancer risk: A Mendelian randomization study. Medicine. vol 101. issue 34. 2022-08-31. PMID:36042675. |
this study aimed to evaluate the potential causal association between genetic variants related to depression and the risk of crc using mendelian randomization (mr). |
2022-08-31 |
2023-08-14 |
Not clear |
| E Wu, Jun-Tao Ni, Tian Xie, Lin Ta. Noncausal effects of genetic predicted depression and colorectal cancer risk: A Mendelian randomization study. Medicine. vol 101. issue 34. 2022-08-31. PMID:36042675. |
two-sample mr analysis using summary data was performed to examine whether depression was causally associated with crc risk. |
2022-08-31 |
2023-08-14 |
Not clear |
| E Wu, Jun-Tao Ni, Tian Xie, Lin Ta. Noncausal effects of genetic predicted depression and colorectal cancer risk: A Mendelian randomization study. Medicine. vol 101. issue 34. 2022-08-31. PMID:36042675. |
based on the results of mr using inverse-variance weighted method, we found that genetically determined major depressive disorder (odds ratio = 1.06, 95% confidence interval = 0.77-1.45) or major depression (odds ratio = 0.77, 95% confidence interval = 0.57-1.04) did not causally increase crc risk. |
2022-08-31 |
2023-08-14 |
Not clear |
| E Wu, Jun-Tao Ni, Tian Xie, Lin Ta. Noncausal effects of genetic predicted depression and colorectal cancer risk: A Mendelian randomization study. Medicine. vol 101. issue 34. 2022-08-31. PMID:36042675. |
the two-sample mr analysis showed that depression is not causally associated with crc risk. |
2022-08-31 |
2023-08-14 |
Not clear |
| Jiahao Zhu, Nini Wang, Houpu Liu, Han Jiang, Bingyue Cai, Dingwan Chen, Yingjun L. Multisite chronic pain as a causal risk factor for coronary artery disease: findings from Mendelian randomization. Pain. 2022-08-02. PMID:35916731. |
we then conducted mr mediation analyses to establish whether body mass index (bmi), smoking, and depression causally mediate any association. |
2022-08-02 |
2023-08-14 |
Not clear |
| Jiahao Zhu, Nini Wang, Houpu Liu, Han Jiang, Bingyue Cai, Dingwan Chen, Yingjun L. Multisite chronic pain as a causal risk factor for coronary artery disease: findings from Mendelian randomization. Pain. 2022-08-02. PMID:35916731. |
in multivariable mr analyses, the excess risk of coronary artery disease was attenuated after adjusting for bmi (or 1.43, 95% ci 1.05 to 1.93), smoking (or 1.49, 95% ci 1.11 to 2.00), depression (or 1.44, 95% ci 1.03 to 2.01), and three risk factors combined (or 1.34, 95% ci 0.88 to 2.05). |
2022-08-02 |
2023-08-14 |
Not clear |
| Shi Yao, Meng Zhang, Shan-Shan Dong, Jia-Hao Wang, Kun Zhang, Jing Guo, Yan Guo, Tie-Lin Yan. Bidirectional two-sample Mendelian randomization analysis identifies causal associations between relative carbohydrate intake and depression. Nature human behaviour. 2022-07-19. PMID:35851841. |
mr evidence suggested a causal relationship between higher relative carbohydrate intake and lower depression risk (odds ratio, 0.42 for depression per one-standard-deviation increment in relative carbohydrate intake; 95% confidence interval, 0.28 to 0.62; p = 1.49 × 10 |
2022-07-19 |
2023-08-14 |
Not clear |
| Frances M K Williams, Elizaveta E Elgaeva, Maxim B Freidin, Olga O Zaytseva, Yurii S Aulchenko, Yakov A Tsepilov, Pradeep Sur. Causal effects of psychosocial factors on chronic back pain: a bidirectional Mendelian randomisation study. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2022-06-06. PMID:35662366. |
we conducted a bi-directional mendelian randomisation (mr) study to examine the causal effects of risk factors (education, smoking, alcohol consumption, physical activity, sleep and depression) on cbp and the causal effect of cbp on the same risk factors. |
2022-06-06 |
2023-08-14 |
Not clear |
| Michela Michielli, Brian Cohe. Cortisol Receptor Sensitivity as a Risk Factor for Depression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560510. |
analysis of the data yielded no significant correlation between snps relating to gr or mr and depression as scored by the beck depression inventory (bdi). |
2022-05-13 |
2023-08-13 |
Not clear |