| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lane G Chen, Justin D Tubbs, Zipeng Liu, Thuan-Quoc Thach, Pak C Sha. Mendelian randomization: causal inference leveraging genetic data. Psychological medicine. 2024-04-19. PMID:38639006. |
we showcase the practical use of mr in psychiatry through three illustrative examples - the connection between cannabis use and psychosis, the link between intelligence and schizophrenia, and the search for modifiable risk factors for depression. |
2024-04-19 |
2024-04-21 |
human |
| Shaobo Guo, Wenhui Zhu, Likai Yu, Lishi Jie, Di Tian, Tianci Zhao, Biqing Zhao, Biao Zhan. The potential causal relationship between various lifestyles and depression: a univariable and multivariable Mendelian randomization study. Frontiers in psychiatry. vol 15. 2024-03-15. PMID:38487581. |
thus, the aim of this study was to examine the causality between multiple lifestyles and depression by mendelian randomization (mr) analysis. |
2024-03-15 |
2024-03-17 |
Not clear |
| Xiao Wang, Shaoming Song, Na Dong, Renjun Lv, Yao He, Yan Zhao, Hongmei Yu. The causal relationship between depression and obstructive sleep apnea: A bidirectional Mendelian randomization study. Journal of psychosomatic research. vol 179. 2024-03-02. PMID:38430795. |
this study aimed to identify the genetic causal relationship between depression and osa using mendelian randomization (mr). |
2024-03-02 |
2024-03-06 |
Not clear |
| Yong Wu, Chu-Yi Zhang, Xiaolan Liu, Lu Wang, Ming Li, Yi Li, Xiao Xia. Shared genetic architecture and causal relationship between sleep behaviors and lifespan. Translational psychiatry. vol 14. issue 1. 2024-02-22. PMID:38388528. |
we found that genetically predicted short sleep duration was causally and negatively associated with lifespan in univariable and multivariable mr analyses, and this effect was partially mediated by coronary artery disease (cad), type 2 diabetes (t2d) and depression. |
2024-02-22 |
2024-02-25 |
Not clear |
| Luxin Zong, Maohong Ge, Jiamiao Wang, Dan Kuang, Hongkai Wei, Zhongbao Wang, Zerui Hu, Chaoben Zhao, Qingmin Jin, Minghui Chen, Chenghui Wan. Causal association between kynurenine and depression investigated using two-sample mendelian randomization. Scientific reports. vol 14. issue 1. 2024-01-20. PMID:38245609. |
therefore, we propose employing a two-sample mendelian randomization (mr) approach to further elucidate the relationship between kyn and depression. |
2024-01-20 |
2024-01-23 |
Not clear |
| Luxin Zong, Maohong Ge, Jiamiao Wang, Dan Kuang, Hongkai Wei, Zhongbao Wang, Zerui Hu, Chaoben Zhao, Qingmin Jin, Minghui Chen, Chenghui Wan. Causal association between kynurenine and depression investigated using two-sample mendelian randomization. Scientific reports. vol 14. issue 1. 2024-01-20. PMID:38245609. |
we utilized extensive data from large-scale genome-wide association studies to identify single nucleotide polymorphisms that act as instrumental variables for kynurenine and depression in european ancestry populations, ensuring compliance with mr assumptions. |
2024-01-20 |
2024-01-23 |
Not clear |
| Luxin Zong, Maohong Ge, Jiamiao Wang, Dan Kuang, Hongkai Wei, Zhongbao Wang, Zerui Hu, Chaoben Zhao, Qingmin Jin, Minghui Chen, Chenghui Wan. Causal association between kynurenine and depression investigated using two-sample mendelian randomization. Scientific reports. vol 14. issue 1. 2024-01-20. PMID:38245609. |
sensitivity tests were conducted using cochran's q test, mr-egger intercept test, mr pleiotropy residual sum and outlier, and leave-one-out analysis.the ivw analysis revealed that each standard deviation increase in kynurenine corresponded to a 1.4-fold increase in the risk of depression (or = 1.351, 95% ci 1.110-1.645, p = 0.003). |
2024-01-20 |
2024-01-23 |
Not clear |
| Zhaoqi Yan, Yifeng Xu, Keke Li, Liangji Li. Increased fruit intake is associated with reduced risk of depression: evidence from cross-sectional and Mendelian randomization analyses. Frontiers in public health. vol 11. 2023-12-29. PMID:38155897. |
this study aimed to investigate the role of fruit intake in the risk of depression using data from the national health and nutrition examination survey (nhanes) and mendelian randomization (mr) analysis, and further explore the causal relationship between them. |
2023-12-29 |
2023-12-31 |
Not clear |
| Xiao Shen, Dongyan Qiao, Yixiao Wang, Nathan Obore, Yuchen Tao, Hong Y. Causal associations of Insomnia and postpartum depression: a two-sample mendelian randomization study. Archives of gynecology and obstetrics. 2023-12-19. PMID:38112721. |
in this study, we evaluate the causal importance of insomnia on postpartum depression using mendelian randomization (mr). |
2023-12-19 |
2023-12-23 |
Not clear |
| Jiajia Wen, Wamei Zhou, Yin Li. Relationship Between the Ovarian Cyst and Depression: A Two-Sample Mendelian Randomization Study. International journal of women's health. vol 15. 2023-12-01. PMID:38020935. |
explore the causal relationship between the ovarian cyst and depression using a two-sample mendelian randomization approach (mr). |
2023-12-01 |
2023-12-07 |
Not clear |
| Jiajia Wen, Wamei Zhou, Yin Li. Relationship Between the Ovarian Cyst and Depression: A Two-Sample Mendelian Randomization Study. International journal of women's health. vol 15. 2023-12-01. PMID:38020935. |
explore the causal relationship between the ovarian cyst and depression using a two-sample mendelian randomization approach (mr). |
2023-11-29 |
2023-12-07 |
Not clear |
| Guang-Hua Deng, Yong-Kang We. The causal relationship between depression and frozen shoulder: A two-sample Mendelian randomization. Medicine. vol 102. issue 44. 2023-11-07. PMID:37933078. |
to investigate the causal relationship between depression and frozen shoulder using a mendelian randomization (mr) approach. |
2023-11-07 |
2023-11-08 |
Not clear |
| Guang-Hua Deng, Yong-Kang We. The causal relationship between depression and frozen shoulder: A two-sample Mendelian randomization. Medicine. vol 102. issue 44. 2023-11-07. PMID:37933078. |
in this study, genetic data were analyzed and explored using a two-sample mr analysis, and the results showed no causal relationship between depression and the occurrence of frozen shoulder, requiring the inclusion of a larger sample for the study. |
2023-11-07 |
2023-11-08 |
Not clear |
| Rick Jansen, Yuri Milaneschi, Daniela Schranner, Gabi Kastenmüller, Matthias Arnold, Xianlin Han, Boadie Dunlop, A Rush, Rima Kaddurah-Daouk, Brenda Pennin. The Metabolome-Wide Signature of Major Depressive Disorder. Research square. 2023-10-04. PMID:37790319. |
metabolites consistently associated with mdd status or depression severity on both occasions were examined in mendelian randomization (mr) analysis using metabolite (n=14,000) and mdd (n=800,000) gwas results. |
2023-10-04 |
2023-10-07 |
human |
| Rick Jansen, Yuri Milaneschi, Daniela Schranner, Gabi Kastenmüller, Matthias Arnold, Xianlin Han, Boadie Dunlop, A Rush, Rima Kaddurah-Daouk, Brenda Pennin. The Metabolome-Wide Signature of Major Depressive Disorder. Research square. 2023-10-04. PMID:37790319. |
mr analyses showed that genetically-predicted higher levels of the lysophospholipid 1-linoleoyl-gpe (18:2) were associated with greater risk of depression. |
2023-10-04 |
2023-10-07 |
human |
| Naidan Zhang, Chunjiao Song, Chaixia Ji, Baibing Xie, Yao Shu, Chengliang Yua. Causality between depression and ankylosing spondylitis in a European population: Results from a Mendelian randomization analysis. Medicine. vol 102. issue 38. 2023-09-25. PMID:37746958. |
the aim of this study was to explore the application of mendelian randomization (mr) egger and inverse variance weighted (ivw) in a causal effect on depression and ankylosing spondylitis (as). |
2023-09-25 |
2023-10-07 |
Not clear |
| Naidan Zhang, Chunjiao Song, Chaixia Ji, Baibing Xie, Yao Shu, Chengliang Yua. Causality between depression and ankylosing spondylitis in a European population: Results from a Mendelian randomization analysis. Medicine. vol 102. issue 38. 2023-09-25. PMID:37746958. |
the 2-sample mr analysis was conducted by mr egger to test the causal effect between depression and as. |
2023-09-25 |
2023-10-07 |
Not clear |
| Naidan Zhang, Chunjiao Song, Chaixia Ji, Baibing Xie, Yao Shu, Chengliang Yua. Causality between depression and ankylosing spondylitis in a European population: Results from a Mendelian randomization analysis. Medicine. vol 102. issue 38. 2023-09-25. PMID:37746958. |
reverse mr analysis suggested that there was no causal effect between as and depression (p > .05). |
2023-09-25 |
2023-10-07 |
Not clear |
| Naidan Zhang, Chunjiao Song, Chaixia Ji, Baibing Xie, Yao Shu, Chengliang Yua. Causality between depression and ankylosing spondylitis in a European population: Results from a Mendelian randomization analysis. Medicine. vol 102. issue 38. 2023-09-25. PMID:37746958. |
depression may be one of the causes of as by mr analysis in a european population. |
2023-09-25 |
2023-10-07 |
Not clear |
| Vasilios Karageorgiou, Francesco Casanova, Jessica O'Loughlin, Harry Green, Trevelyan J McKinley, Jack Bowden, Jessica Tyrrel. Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study. BMC medicine. vol 21. issue 1. 2023-09-14. PMID:37710313. |
we aim to investigate inflammation, proxied by c-reactive protein (crp) levels, and body mass index (bmi) as putative causal risk factors for depression and subsequent treatment resistance, leveraging genetic information to avoid confounding via mendelian randomisation (mr). |
2023-09-14 |
2023-10-07 |
Not clear |