| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rick Jansen, Yuri Milaneschi, Daniela Schranner, Gabi Kastenmüller, Matthias Arnold, Xianlin Han, Boadie Dunlop, A Rush, Rima Kaddurah-Daouk, Brenda Pennin. The Metabolome-Wide Signature of Major Depressive Disorder. Research square. 2023-10-04. PMID:37790319. |
mr analyses showed that genetically-predicted higher levels of the lysophospholipid 1-linoleoyl-gpe (18:2) were associated with greater risk of depression. |
2023-10-04 |
2023-10-07 |
human |
| Naidan Zhang, Chunjiao Song, Chaixia Ji, Baibing Xie, Yao Shu, Chengliang Yua. Causality between depression and ankylosing spondylitis in a European population: Results from a Mendelian randomization analysis. Medicine. vol 102. issue 38. 2023-09-25. PMID:37746958. |
the aim of this study was to explore the application of mendelian randomization (mr) egger and inverse variance weighted (ivw) in a causal effect on depression and ankylosing spondylitis (as). |
2023-09-25 |
2023-10-07 |
Not clear |
| Naidan Zhang, Chunjiao Song, Chaixia Ji, Baibing Xie, Yao Shu, Chengliang Yua. Causality between depression and ankylosing spondylitis in a European population: Results from a Mendelian randomization analysis. Medicine. vol 102. issue 38. 2023-09-25. PMID:37746958. |
the 2-sample mr analysis was conducted by mr egger to test the causal effect between depression and as. |
2023-09-25 |
2023-10-07 |
Not clear |
| Naidan Zhang, Chunjiao Song, Chaixia Ji, Baibing Xie, Yao Shu, Chengliang Yua. Causality between depression and ankylosing spondylitis in a European population: Results from a Mendelian randomization analysis. Medicine. vol 102. issue 38. 2023-09-25. PMID:37746958. |
reverse mr analysis suggested that there was no causal effect between as and depression (p > .05). |
2023-09-25 |
2023-10-07 |
Not clear |
| Naidan Zhang, Chunjiao Song, Chaixia Ji, Baibing Xie, Yao Shu, Chengliang Yua. Causality between depression and ankylosing spondylitis in a European population: Results from a Mendelian randomization analysis. Medicine. vol 102. issue 38. 2023-09-25. PMID:37746958. |
depression may be one of the causes of as by mr analysis in a european population. |
2023-09-25 |
2023-10-07 |
Not clear |
| Vasilios Karageorgiou, Francesco Casanova, Jessica O'Loughlin, Harry Green, Trevelyan J McKinley, Jack Bowden, Jessica Tyrrel. Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study. BMC medicine. vol 21. issue 1. 2023-09-14. PMID:37710313. |
we aim to investigate inflammation, proxied by c-reactive protein (crp) levels, and body mass index (bmi) as putative causal risk factors for depression and subsequent treatment resistance, leveraging genetic information to avoid confounding via mendelian randomisation (mr). |
2023-09-14 |
2023-10-07 |
Not clear |
| Mengyang Chu, Shengxian Shen, Zhenlai Zhu, Zhiguo Li, Yaxing Bai, Jingyi Ma, Junfeng Hao, Lei Wang, Meng Fu, Erle Dang, Gang Wang, Shuai Sha. Association of psoriasis with depression, anxiety, and suicidality: A bidirectional two-sample Mendelian randomization study. The Journal of dermatology. 2023-09-12. PMID:37697936. |
to investigate the cause-effect relationships between psoriasis and mental disorders including depression, anxiety, and suicidality, we conducted a bidirectional two-sample mendelian randomization (mr) study utilizing summary statistics from the most comprehensive genome-wide association studies of psoriasis (n = 306 123), broad depression (n = 500 199), major depressive disorder (n = 173 005), anxiety (n = 17 310), and suicide attempts (n = 50 264). |
2023-09-12 |
2023-10-07 |
Not clear |
| Mengyang Chu, Shengxian Shen, Zhenlai Zhu, Zhiguo Li, Yaxing Bai, Jingyi Ma, Junfeng Hao, Lei Wang, Meng Fu, Erle Dang, Gang Wang, Shuai Sha. Association of psoriasis with depression, anxiety, and suicidality: A bidirectional two-sample Mendelian randomization study. The Journal of dermatology. 2023-09-12. PMID:37697936. |
using the random-effects inverse-variance weighted method as primary method, the forward mr analyses indicated that psoriasis was significantly associated with higher odds of broad depression (odds ratio [or] 1.030, 95% confidence interval [ci] 1.010-1.051, p = 0.003) and suggestively associated with an increased risk of major depressive disorder (or 1.054, 95% ci 1.002-1.109, p = 0.040), but not with the risk of anxiety (p = 0.160) or suicide attempts (p = 0.648). |
2023-09-12 |
2023-10-07 |
Not clear |
| Mengyang Chu, Shengxian Shen, Zhenlai Zhu, Zhiguo Li, Yaxing Bai, Jingyi Ma, Junfeng Hao, Lei Wang, Meng Fu, Erle Dang, Gang Wang, Shuai Sha. Association of psoriasis with depression, anxiety, and suicidality: A bidirectional two-sample Mendelian randomization study. The Journal of dermatology. 2023-09-12. PMID:37697936. |
in reverse mr analyses, significant causal impact of broad depression (or 1.363, 95% ci 1.103-1.684, p = 0.004) and major depressive disorder (or 1.890, 95% ci 1.285-2.781, p = 0.001), but not anxiety (p = 0.787) and suicide attempts (p = 0.961) on psoriasis risk was observed. |
2023-09-12 |
2023-10-07 |
Not clear |
| Mengyang Chu, Shengxian Shen, Zhenlai Zhu, Zhiguo Li, Yaxing Bai, Jingyi Ma, Junfeng Hao, Lei Wang, Meng Fu, Erle Dang, Gang Wang, Shuai Sha. Association of psoriasis with depression, anxiety, and suicidality: A bidirectional two-sample Mendelian randomization study. The Journal of dermatology. 2023-09-12. PMID:37697936. |
in conclusion, this mr study indicates a bidirectional causal relationship between psoriasis and depression that was previously unrecognized, which highlights the significance of screening for depression in psoriasis patients and initiating appropriate interventions. |
2023-09-12 |
2023-10-07 |
Not clear |
| Haohao Zhu, Yifan Sun, Shuaiyi Guo, Qin Zhou, Ying Jiang, Yuan Shen, Zhenhe Zhou, Zhiqiang Du, Hongliang Zho. Causal relationship between sex hormone-binding globulin and major depression: A Mendelian randomization study. Acta psychiatrica Scandinavica. 2023-09-08. PMID:37681458. |
this study aimed to explore the causal relationship between sex hormone-binding globulin (shbg) and major depression using two-sample mendelian randomization (mr) studies. |
2023-09-08 |
2023-10-07 |
Not clear |
| Kristin Klaeske, Constantin Schreiber, Sandra Eifert, Tillmann Dieterlen, Khalil Jawad, Diyar Saeed, Sandra Semmig-Könze, Anna Lassia Meyer, Michael Andrew Borger, Maja-Theresa Dieterle. Health status analysis is comparable in HM3 patients with different preoperative grades of mitral regurgitation. Journal of patient-reported outcomes. vol 7. issue 1. 2023-08-24. PMID:37615830. |
we investigated different parameters of health status including exercise capacity, anxiety and depression after lvad implantation in patients with different preoperative grades of mitral regurgitation (mr). |
2023-08-24 |
2023-09-07 |
Not clear |
| Ni Sang, Bo-Han Li, Meng-Yao Zhang, Meng Wei, Ruo-Xuan Fang, Wen-Jing Liu, Li-E Huang, Jing Zhang, Guo-Cui W. Bidirectional causal relationship between depression and frailty: a univariate and multivariate Mendelian randomisation study. Age and ageing. vol 52. issue 7. 2023-07-02. PMID:37392400. |
therefore, this study used a bidirectional two-sample mendelian randomisation (mr) study to investigate the causal relationship between depression and frailty. |
2023-07-02 |
2023-08-14 |
Not clear |
| Mengyu Pan, James M Roe, Ron Nudel, Andrew J Schork, Olena Iakunchykova, Anders M Fjell, Kristine B Walhovd, Thomas Werge, Chi-Hua Chen, Michael E Benros, Yunpeng Wan. Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study. Translational psychiatry. vol 13. issue 1. 2023-05-24. PMID:37225692. |
we applied two-sample mendelian randomization (mr) on the association statistics from genome-wide association studies (gwas) for circulating s100b levels measured 5-7 days after birth (the ipsych sample) and in an older adult sample (mean age, 72.5 years; the lothian sample), upon those derived from major depression disorder (mdd), schizophrenia (scz), bipolar disorder (bip), autism spectral disorder (asd), alzheimer's disease (ad), and parkinson's disease (pd). |
2023-05-24 |
2023-08-14 |
Not clear |
| Ole-Jørgen Bekkevold, Jan Kristian Damås, Ben Michael Brumpton, Bjørn Olav Åsvol. The causal role of C-reactive protein and interleukin-6 on anxiety and depression symptoms and life satisfaction: Mendelian randomisation analyses in the HUNT study. Psychological medicine. 2023-05-22. PMID:37217205. |
a recent mendelian randomisation (mr) study suggested that crp may decrease and il-6 may increase anxiety and depression symptoms. |
2023-05-22 |
2023-08-14 |
Not clear |
| Xixian Ruan, Jie Chen, Yuhao Sun, Yao Zhang, Jianhui Zhao, Xiaoyan Wang, Xue Li, Shuai Yuan, Susanna C Larsso. Depression and 24 gastrointestinal diseases: a Mendelian randomization study. Translational psychiatry. vol 13. issue 1. 2023-05-04. PMID:37142593. |
we conducted mendelian randomization (mr) analyses to systematically explore the associations of depression with 24 gastrointestinal diseases. |
2023-05-04 |
2023-08-14 |
Not clear |
| Xixian Ruan, Jie Chen, Yuhao Sun, Yao Zhang, Jianhui Zhao, Xiaoyan Wang, Xue Li, Shuai Yuan, Susanna C Larsso. Depression and 24 gastrointestinal diseases: a Mendelian randomization study. Translational psychiatry. vol 13. issue 1. 2023-05-04. PMID:37142593. |
this mr study suggests that depression may play a causal role in many gastrointestinal diseases. |
2023-05-04 |
2023-08-14 |
Not clear |
| Jiayue-Clara Jiang, Chenwen Hu, Andrew M McIntosh, Sonia Sha. Investigating the potential anti-depressive mechanisms of statins: a transcriptomic and Mendelian randomization analysis. Translational psychiatry. vol 13. issue 1. 2023-04-04. PMID:37015906. |
mr analysis did not identify any significant associations between statin exposure and depression risk or symptoms after multiple testing correction. |
2023-04-04 |
2023-08-14 |
human |
| Xianjie Wan, Jiale Xie, Mingyi Yang, Hui Yu, Weikun Hou, Ke Xu, Jiachen Wang, Peng X. Does Having Rheumatoid Arthritis Increase the Dose of Depression Medications? A Mendelian Randomization Study. Journal of clinical medicine. vol 12. issue 4. 2023-02-25. PMID:36835939. |
therefore, in this study, we used two-sample mendelian randomization (mr) to explore whether ra increases the dose of depression medications and gain a more comprehensive understanding of the relationship between ra and depression. |
2023-02-25 |
2023-08-14 |
Not clear |
| Lingsi Zeng, Honggang Lv, Xubo Wang, Ranran Xue, Cong Zhou, Xia Liu, Hao Y. Causal effects of fatty acids on depression: Mendelian randomization study. Frontiers in nutrition. vol 9. 2022-12-23. PMID:36562041. |
we aimed to investigate the potential causal relationship between fa [saturated fatty acids (sfa), mono-unsaturated fatty acids (mufa), and polyunsaturated fatty acids (pufa)] and the risk of depression using mendelian randomization (mr) analysis. |
2022-12-23 |
2023-08-14 |
Not clear |