| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Burak Yuluğ, Erol Ozan, Ali Saffet Gönül, Ertugrul Kili. Brain-derived neurotrophic factor, stress and depression: a minireview. Brain research bulletin. vol 78. issue 6. 2009-03-13. PMID:19111910. |
considering the data that stress plays an important role by the development of depression which is characterized with prominent hippocampal cell death, as well as the well known neuroprotective effects of bdnf, we aimed to investigate the link between the bdnf, stress and depression. |
2009-03-13 |
2023-08-12 |
Not clear |
| Smita Thakker-Varia, Janet Alde. Neuropeptides in depression: role of VGF. Behavioural brain research. vol 197. issue 2. 2009-02-23. PMID:18983874. |
one class of genes regulated by both bdnf and serotonin (5-ht) are neuropeptides including vgf (non-acryonimic) which has a novel role in depression. |
2009-02-23 |
2023-08-12 |
Not clear |
| Smita Thakker-Varia, Janet Alde. Neuropeptides in depression: role of VGF. Behavioural brain research. vol 197. issue 2. 2009-02-23. PMID:18983874. |
we summarize experimental data describing the roles of bdnf, vgf and other neuropeptides in depression and how they may be acting through the generation of new neurons and altered synaptic activity. |
2009-02-23 |
2023-08-12 |
Not clear |
| Srijan Sen, Ronald Duman, Gerard Sanacor. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biological psychiatry. vol 64. issue 6. 2009-02-17. PMID:18571629. |
converging lines of evidence implicate the neurotrophin brain-derived neurotrophic factor (bdnf) in the pathophysiology of major depression. |
2009-02-17 |
2023-08-12 |
Not clear |
| Srijan Sen, Ronald Duman, Gerard Sanacor. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biological psychiatry. vol 64. issue 6. 2009-02-17. PMID:18571629. |
recent studies have begun to explore the relationship between serum bdnf and depression. |
2009-02-17 |
2023-08-12 |
Not clear |
| Teresa F Ackermann, Heide Hörtnagl, David P Wolfer, Giovanni Colacicco, Reinhard Sohr, Florian Lang, Rainer Hellweg, Undine E Lan. Phosphatidylinositide dependent kinase deficiency increases anxiety and decreases GABA and serotonin abundance in the amygdala. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 22. issue 5-6. 2009-02-10. PMID:19088455. |
conversely, anxiety disorders and depression may be reversed by brain-derived neurotrophic factor (bdnf). |
2009-02-10 |
2023-08-12 |
mouse |
| André Russowsky Brunoni, Mariana Lopes, Felipe Fregn. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18752720. |
a systematic review and meta-analysis of clinical studies on major depression and bdnf levels: implications for the role of neuroplasticity in depression. |
2009-01-26 |
2023-08-12 |
human |
| André Russowsky Brunoni, Mariana Lopes, Felipe Fregn. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18752720. |
several clinical studies on major depressive disorder (mdd) have shown that blood brain-derived neurotrophic factor (bdnf) - a factor used to index neuroplasticity - is associated with depression response; however, the results are mixed. |
2009-01-26 |
2023-08-12 |
human |
| André Russowsky Brunoni, Mariana Lopes, Felipe Fregn. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18752720. |
the purpose of our study was to evaluate whether bdnf levels are correlated with improvement of depression. |
2009-01-26 |
2023-08-12 |
human |
| André Russowsky Brunoni, Mariana Lopes, Felipe Fregn. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18752720. |
in addition, there was a significant correlation between changes in bdnf level and depression scores changes (p=0.02). |
2009-01-26 |
2023-08-12 |
human |
| André Russowsky Brunoni, Mariana Lopes, Felipe Fregn. A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. The international journal of neuropsychopharmacology. vol 11. issue 8. 2009-01-26. PMID:18752720. |
our results show that bdnf levels are associated with clinical changes in depression; supporting the notion that depression improvement is associated with neuroplastic changes. |
2009-01-26 |
2023-08-12 |
human |
| Chi-Un Pae, David M Marks, Changsu Han, Ashwin A Patkar, David Steffen. Does neurotropin-3 have a therapeutic implication in major depression? The International journal of neuroscience. vol 118. issue 11. 2009-01-16. PMID:18853330. |
bdnf has been consistently implicated in the pathogenesis of depression and the therapeutic mechanism of antidepressants. |
2009-01-16 |
2023-08-12 |
Not clear |
| Shih-Jen Tsai, Chen-Jee Hong, Ying-Jay Lio. Brain-derived neurotrophic factor and antidepressant action: another piece of evidence from pharmacogenetics. Pharmacogenomics. vol 9. issue 9. 2009-01-12. PMID:18781861. |
the neurotrophin hypothesis of depression and antidepressant drug action postulates that reduced activity of neurotrophic factors, particularly brain-derived neurotrophic factor (bdnf), plays an important role in the pathogenesis of major depression, and that its restoration may represent a critical mechanism underlying antidepressant therapeutic effect. |
2009-01-12 |
2023-08-12 |
Not clear |
| Shih-Jen Tsai, Chen-Jee Hong, Ying-Jay Lio. Brain-derived neurotrophic factor and antidepressant action: another piece of evidence from pharmacogenetics. Pharmacogenomics. vol 9. issue 9. 2009-01-12. PMID:18781861. |
first, the study included not only major depression but also bipolar disorder patients; second, various antidepressants were used in this study, which could affect patients' responses; third, the frequency of the haplotype associated with treatment response is rare; and fourth, previous studies of the effects of single bdnf polymorphisms on antidepressant action have reported conflicting findings. |
2009-01-12 |
2023-08-12 |
Not clear |
| Hwa-Young Lee, Yong-Ku Ki. Plasma brain-derived neurotrophic factor as a peripheral marker for the action mechanism of antidepressants. Neuropsychobiology. vol 57. issue 4. 2008-12-30. PMID:18679038. |
numerous studies have demonstrated that depression is associated with a decreased expression of brain-derived neurotrophic factor (bdnf). |
2008-12-30 |
2023-08-12 |
human |
| Hwa-Young Lee, Yong-Ku Ki. Plasma brain-derived neurotrophic factor as a peripheral marker for the action mechanism of antidepressants. Neuropsychobiology. vol 57. issue 4. 2008-12-30. PMID:18679038. |
plasma bdnf levels and hamilton depression rating scales were measured at baseline and 6 weeks after antidepressant administration. |
2008-12-30 |
2023-08-12 |
human |
| Christian Montag, Martin Reuter, Beate Newport, Christian Elger, Bernd Webe. The BDNF Val66Met polymorphism affects amygdala activity in response to emotional stimuli: evidence from a genetic imaging study. NeuroImage. vol 42. issue 4. 2008-12-29. PMID:18603005. |
due to its potential involvement in psychiatric diseases like depression and anxiety disorders bdnf lately became a major target in research. |
2008-12-29 |
2023-08-12 |
human |
| Lina Chen, Debbie A Lawlor, Sarah J Lewis, Wei Yuan, Mohammad R Abdollahi, Nicholas J Timpson, Ian N M Day, Shah Ebrahim, George Davey Smith, Yin Y Shugar. Genetic association study of BDNF in depression: finding from two cohort studies and a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18205169. |
genetic association study of bdnf in depression: finding from two cohort studies and a meta-analysis. |
2008-12-04 |
2023-08-12 |
human |
| Lina Chen, Debbie A Lawlor, Sarah J Lewis, Wei Yuan, Mohammad R Abdollahi, Nicholas J Timpson, Ian N M Day, Shah Ebrahim, George Davey Smith, Yin Y Shugar. Genetic association study of BDNF in depression: finding from two cohort studies and a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18205169. |
population-based genetic studies have examined the association between bdnf and a variety of depression outcomes, but the results have not clearly established the role of bdnf in the development of this complex disorder. |
2008-12-04 |
2023-08-12 |
human |
| Lina Chen, Debbie A Lawlor, Sarah J Lewis, Wei Yuan, Mohammad R Abdollahi, Nicholas J Timpson, Ian N M Day, Shah Ebrahim, George Davey Smith, Yin Y Shugar. Genetic association study of BDNF in depression: finding from two cohort studies and a meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 6. 2008-12-04. PMID:18205169. |
the aim of this study was to test for associations between two genetic variants in bdnf, val66met (rs6265) and -270 c > t, and depression measured in two independent samples. |
2008-12-04 |
2023-08-12 |
human |